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1. 发明申请

WO2013130576A1 A NUTRACUETICAL COMPOUNDING SYSTEM AND METHOD THEREFORE 审中-公开
标题翻译：一种营养化合物系统及其方法
公开(公告)号：WO2013130576A1
公开(公告)日：2013-09-06
申请号：PCT/US2013/027982
申请日：2013-02-27
申请人： PURPOD HOLDINGS, LLC , OCHOA, Gian-Carlo , DUFFY, Brendan , TAYLOR, Jon , VAN DEURSEN, Gary
发明人： OCHOA, Gian-Carlo , DUFFY, Brendan , TAYLOR, Jon , VAN DEURSEN, Gary
IPC分类号： A47J31/00
CPC分类号： A47J31/407 , A23L2/52 , A23L29/00 , A23L33/10 , A23V2002/00 , A47J31/401 , A47J31/4492 , B01F3/12 , B01F3/1271 , B01F7/00008 , B01F15/00123 , B01F15/00305 , B01F15/00311 , B01F15/0206 , B01F2215/0032 , G07F13/065
摘要： The present invention relates to a system and process for a nutracuetical beverage compounding system and methods for the same. Provided is a customizable supplement beverage system and method for personalizing and operating the same to a particular user and optionally for operative tracking. Proposed additionally is an operative system for receiving and individually identifying a concentrate or supplement combinations, for mixing the same prior to a use, and for dispensing the same for use, and for tracking control factors relating to the same,
摘要翻译：本发明涉及营养饮料复合系统的系统和方法及其方法。提供了一种可定制的补充饮料系统和方法，用于将其个性化并且操作到特定用户并且可选地用于操作跟踪。还提出了一种操作系统，用于接收和单独地识别浓缩物或补充剂组合，用于在使用之前混合浓缩物或补充剂组合，并用于分配其使用，并用于跟踪与其相关的控制因素，

2. 发明申请

WO2003059520A1 GRANULATING MIXERS 审中-公开
标题翻译：造粒机
公开(公告)号：WO2003059520A1
公开(公告)日：2003-07-24
申请号：PCT/EP2003/000881
申请日：2003-01-09
申请人： DOW CORNING CORPORATION , DESCAMPS, Pierre , MICHEL, Bertrand , THIBAUT, Marc
发明人： DESCAMPS, Pierre , MICHEL, Bertrand , THIBAUT, Marc
IPC分类号： B02C18/08
CPC分类号： B01F7/00316 , B01F7/00008 , B01F7/00425 , B01F7/04 , B02C18/08 , B02C18/18
摘要： A mixer blade which is adapted to be mounted on the shaft of a vertical continuous granulating mixer, characterised in that an inner portion of the leading edge of the blade is bevelled upwards and an outer portion of the leading edge of the blade is substantially vertical or is bevelled downwards. A vertical continuous granulating mixer which comprises a shaft fitted with blades rotating within a tubular housing and having an inlet for solid particles and a spray inlet for liquid to contact the solid particles above the blades, characterised in that an inner portion of at least one of the blades is angled forwards and upwards over at least part of its area so that particles hitting the angled portion of the blade acquire an upwards velocity component.
摘要翻译：一种适于安装在垂直连续造粒混合器的轴上的混合器叶片，其特征在于，叶片前缘的内部部分向上倾斜并且叶片的前缘的外部部分基本垂直或向下倾斜。一种垂直连续造粒混合器，其包括装配有在管状壳体内旋转并具有用于固体颗粒的入口的叶片的轴和用于液体接触固体颗粒在叶片上方的喷雾入口，其特征在于，至少一个叶片在其区域的至少一部分上向前和向上成角度，使得撞击叶片的成角度部分的颗粒获得向上的速度分量。

3. 发明申请

WO1997017840A1 SCREW FEEDERS WITH PERFECTED PROFILE FOR CUTTER-MIXER-FEEDER WAGON FOR FODDER AND GRASS OR STRAW SILAGE 审中-公开
标题翻译：螺丝供料器，用于切割机 - 搅拌机喂料器，具有良好的配方，适用于炉子和草或泥土
公开(公告)号：WO1997017840A1
公开(公告)日：1997-05-22
申请号：PCT/EP1996000934
申请日：1996-03-06
申请人： SEKO S.P.A. , LOPPOLI, Giuseppe
发明人： SEKO S.P.A.
IPC分类号： A01K05/00
CPC分类号： B01F7/00008 , A01F29/005 , A01K5/002 , B01F7/02 , B01F7/088 , B01F13/0035 , B01F13/004 , B01F2215/0008 , Y10S241/605
摘要： The invention is a cutter-mixer-feeder wagon for fodder and grass or straw silage, comprising at least two rotary screw feeders (7), housed inside a compartment (75) with curved section obtained on the bottom (76) of the container (2) itself, each one provided with at least one pair of spirals (9, 10), on which peripheral cutters (13) are fixed, one of said spirals being wound clockwise (10) and the other anticlockwise (9), starting from the ends of the screw feeder and such as to convey the processed material towards the area where said right and left spirals converge. Each one of said spirals (9, 10) is provided, on its end facing the other spiral, with two or more discharge openings obtained on its profile (91, 92, 93; 101, 102, 103), each one of said openings being carried out by removing a portion of the spiral, where each discharge opening is formed by a substantially radial segment and by an arc-shaped part that are substantially orthogonal to each other, while said right and left spirals are interrupted at about 180 DEG from each other, until they touch an ideal plane that intersects the longitudinal axis of the screw feeders.
摘要翻译：本发明是一种用于饲料和草料或秸秆青贮饲料的切割机 - 搅拌机 - 进料车，包括至少两个旋转螺旋给料器（7），容纳在具有在容器底部（76）上获得的弯曲部分的隔室（75）内 2）本身，每一个设置有至少一对螺旋（9,10），周边刀具（13）固定在其上，所述螺旋中的一个沿顺时针（10）和另一个逆时针方向（9）缠绕，从螺旋进料器的端部，并且将经处理的材料输送到所述左右螺旋会聚的区域。所述螺旋（9,10）中的每一个在其面向另一个螺旋的端部上设置有在其轮廓（91,92,93; 101,102,103）上获得的两个或更多个排出开口，每个所述开口通过去除螺旋的一部分进行，其中每个排出口由基本上径向的部分和基本上彼此正交的弧形部分形成，而所述左右螺旋在约180° 直到它们接触到与螺旋给料器的纵向轴线相交的理想平面。

4. 发明申请

WO2012110570A1 DEVICE AND METHOD FOR PRODUCTION AND ANALYSIS OF PRIONS 审中-公开
标题翻译：用于生产和分析的设备和方法
公开(公告)号：WO2012110570A1
公开(公告)日：2012-08-23
申请号：PCT/EP2012/052634
申请日：2012-02-15
申请人： HELMHOLTZ-ZENTRUM FÜR INFEKTIONSFORSCHUNG GMBH , LÜHRS, Thorsten , DELUWEIT, Frank
发明人： LÜHRS, Thorsten , DELUWEIT, Frank
IPC分类号： B01F7/28 , C07K14/47
CPC分类号： B01F11/0225 , B01F7/00008 , B01F7/00541 , B01F7/008 , B01F11/0258 , B01F13/0836 , B01F13/0845 , B01F15/00006 , B01F15/00389 , B01F15/00707 , B01F15/0072 , B01F2215/0073 , B01F2215/0427 , B01F2215/0431 , B01F2215/0454 , B01F2215/0477 , B01F2215/0481 , C07K14/47
摘要： The invention provides a method for producing prion protein having an aggregated conformation by contacting native conformation prion protein with aggregated conformation prion protein in a liquid preparation and subjecting this to at least one cycle or to a number of cycles of application of shear-force for fragmenting aggregates of prion protein, wherein the shear-force applied is precisely controlled. In addition to this process for amplification of aggregated state prion protein from native conformation prion protein, the invention relates to the aggregated state prion protein obtained by the amplification process, which aggregated state prion protein has one conformation, which is e.g. identical within one batch and reproducible between batches, e.g. as detectable by proteinase resistance in a Western blot.
摘要翻译：本发明提供了通过使天然构象朊病毒蛋白与聚集的构象朊病毒蛋白在液体制剂中接触而制备具有聚集构象的朊病毒蛋白的方法，并且对其进行至少一个循环或多个施加剪切力以循环的循环朊病毒蛋白的聚集体，其中施加的剪切力被精确地控制。本发明涉及通过扩增方法获得的聚合状态朊病毒蛋白，该聚合状态朊病毒蛋白具有一个构象。在一批内相同，并且在批次之间可再现。在Western印迹中可通过蛋白酶抗性检测。

5. 发明申请

WO02074426A8 DYNAMIC MIXER 审中-公开
标题翻译：动态混合器
公开(公告)号：WO02074426A8
公开(公告)日：2005-03-10
申请号：PCT/EP0202481
申请日：2002-03-06
申请人： 3M ESPE AG , PAUSER HELMUT , WAGNER INGO
发明人： PAUSER HELMUT , WAGNER INGO
IPC分类号： B01F3/10 , B01F7/00 , B01F7/16 , B01F13/00 , B01F15/00 , B01F15/02
CPC分类号： B01F7/00008 , B01F7/00 , B01F13/002 , B01F15/0201 , B01F2215/0027 , B01F2215/0039 , B05C17/00516
摘要： The invention relates to a dynamic mixer for mixing at least two paste components of different volume proportions. Said mixer comprises a housing with at least two inlet openings and at least one outlet opening, a mixer element being rotatably mounted in a mixing chamber of said housing. The housing has at least one delay chamber comprising a limiting wall that blocks the paste stream in the direction of flow and at least one opening that opens into the mixing chamber, said opening(s) being set back in relation to the limiting wall. The mixer is particularly suitable for mixing paste components with a relatively high viscosity of, for example, greater than 800 Pas.
摘要翻译：本发明涉及一种动力混合器，用于混合具有不同体积分数至少两个浆料组分，其包含具有至少两个入口开口和至少一个出口开口，其中，混合元件可旋转地安装在混合室的壳体，其中所述壳体的至少一个具有膏当前延迟室具有流动停止边界壁和通向混合室的至少一个开口的方向上，该至少一个开口的边界壁是凹陷的。混合是特别适合于浆料组分混合具有相对高的粘度，例如大于800个PAS更大。

6. 发明申请

WO1997017841A1 CUTTER-MIXER-FEEDER WAGON FOR FODDER AND GRASS OR STRAW SILAGE, PROVIDED WITH PROFILED PLATE TO CONVEY THE MATERIAL TO BE PROCESSED 审中-公开
标题翻译：切割机 - 送料机WAGON FOR FODDER和GRASS或STRILS SILAGE，提供与配置板输送要处理的材料
公开(公告)号：WO1997017841A1
公开(公告)日：1997-05-22
申请号：PCT/EP1996000935
申请日：1996-03-06
申请人： SEKO S.P.A. , LOPPOLI, Giuseppe
发明人： SEKO S.P.A.
IPC分类号： A01K05/00
CPC分类号： B01F7/00008 , A01F29/005 , A01K5/002 , B01F7/02 , B01F7/088 , B01F13/0035 , B01F13/004 , B01F2215/0008
摘要： The invention is a cutter-mixer-feeder wagon for fodder and grass or straw silage, comprising at least one rotary screw feeder (7), housed inside a compartment (75) with curved section obtained on the bottom (76) of the container (2) itself and provided with at least one pair of spirals (9, 10), on which peripheral cutters (13) are fixed, one of said spirals being wound clockwise (10) and the other anticlockwise (9), starting from the ends of the screw feeder and such as to convey the processed material towards the area where said right and left spirals converge. Said wagon is provided with profiled plates (30, 31, 32) that convey the material to be processed into the wagon and are positioned on each longitudinal wall (25, 26) of the wagon itself, near the compartments in which the screw feeders (7) are housed, and shaped in such a way as to reduce the space between the screw feeder and the longitudinal wall of the wagon, said conveying plate closing the space between the screw feeder (7) and the side wall of the wagon, so as to convey the material along the longitudinal axis of the screw feeder, towards the unloading door for the processed material.
摘要翻译：本发明是一种用于饲料和草料或秸秆青贮饲料的切割机 - 混合器 - 饲料机，包括至少一个旋转螺旋给料器（7），容纳在具有在容器的底部（76）上获得的弯曲部分的隔室（75）内 2）本身并且设置有至少一对螺旋（9,10），其上固定有周边切割器（13），所述螺旋中的一个沿着顺时针（10）和另一个逆时针方向（9）从端部并且将所处理的材料输送到所述左右螺旋会聚的区域。所述货车设置有成型板（30,31,32），其将要加工的材料输送到货车中并且位于货车本身的每个纵向壁（25,26）上，靠近其中螺旋送料器 7）被容纳和成形以减小螺旋进料器与货车的纵向壁之间的空间，所述输送板关闭螺旋进料器（7）和货车侧壁之间的空间，因此以沿着螺旋给料器的纵向轴线将材料输送到处理材料的卸载门。

7. 发明申请

WO2014053276A1 RÜHREREINBAUHILFE UND VERFAHREN ZUM EINBAU EINES RÜHRORGANS IN EINEN BIOREAKTOR 审中-公开
标题翻译： RÜHREREINBAUHILFEAND METHOD FOR安装的搅拌元件的注入生物反应器
公开(公告)号：WO2014053276A1
公开(公告)日：2014-04-10
申请号：PCT/EP2013/067928
申请日：2013-08-29
申请人： SARTORIUS STEDIM BIOTECH GMBH
发明人： DREHER, Thomas , SCHEIBE, Oliver , GRELLER, Gerhard , HUSEMANN, Ute , REIF, Oscar-Werner
IPC分类号： C12M1/06
CPC分类号： B01F15/00 , B01F7/00008 , B01F15/00922 , C12M27/02 , Y10T29/49316
摘要： Verwendung einer Hülse, die einen zwischen ihren axialen Enden verlaufenden, von gegenüberliegenden Flanken der Wandung begrenzten Schlitz aufweist, als entfernbare Rührereinbauhilfe zum Positionieren eines Rührorgans an einer Rührerwelle eines Bioreaktors. Verfahren zum Einbau eines Rührorgans an einer in einem Bioreaktor angeordneten Rührerwelle, wobei die folgenden Schritte durchgeführt werden: a) Aufstecken einer in ihrer axialen Längsrichtung über ihre gesamte Hülsenlänge geschlitzte Hülse, die eine Rührereinbauhilfe bildet, auf die Rührerwelle, b) Aufstecken des Rührorgans auf das freie Ende der Rührerwelle bis es an das benachbarte Ende der Hülse aufschlägt, c) Fixieren des Rührorgans an der Rührerwelle, und d) Entfernen der Rührereinbauhilfe. Bioreaktor mit einer von einem Antrieb antreibbaren Rührerwelle auf der ein Rührorgan positioniert ist, wobei die Position des Rührorgans von einer Rührereinbauhilfe bestimmt ist, an deren freies Ende das Rührorgan mit einer Anschlagfläche anschlägt, dass die Rührereinbauhilfe als eine Hülse ausgebildet ist, die einen zwischen ihren axialen Enden verlaufenden, von gegenüberliegenden Flanken der Wandung begrenzten Schlitz aufweist und auf die Rührerwelle aufgesteckt ist, und dass die Rührereinbauhilfe seitlich von der Rührerwelle abziehbar ist.
摘要翻译：使用具有其轴向之间延伸的通道的套筒端部由壁槽为可移动Rührereinbauhilfe用于在生物反应器的搅拌轴定位的搅拌器的相对边缘界定。一种用于在布置在一个生物反应器中搅拌轴安装一搅拌元件，其特征在于，执行以下步骤：a）在其轴向长度方向在其整个套筒长度附接于开槽，其形成一个Rührereinbauhilfe在搅拌轴上套筒，b）将所述搅拌器搅拌器轴的自由端，直到它碰到抵靠套筒，c）该搅拌元件的搅拌器轴的固定，和d）移除所述Rührereinbauhilfe的相邻端部。与可驱动通过在其上搅拌器定位在驱动搅拌器轴，其中，所述搅拌元件的位置由Rührereinbauhilfe确定生物反应器，与止挡面抵靠该Rührereinbauhilfe的自由端部的搅拌元件被形成为具有它们之间的一个套筒被延伸的轴向端部，从有限的狭槽的壁的相对侧部具有与附接到搅拌轴，并且该Rührereinbauhilfe是从搅拌器轴横向地可移动的。

8. 发明申请

WO2013006613A1 METHODS OF MANUFACTURING TOPICAL COMPOSITIONS AND APPARATUS FOR SAME 审中-公开
标题翻译：制备局部组合物的方法和装置
公开(公告)号：WO2013006613A1
公开(公告)日：2013-01-10
申请号：PCT/US2012/045390
申请日：2012-07-03
申请人： NOVAN, INC. , KOUGOULOS, Eleftherios , STASKO, Nathan
发明人： KOUGOULOS, Eleftherios , STASKO, Nathan
IPC分类号： A61K9/00
CPC分类号： A61K31/655 , A61K9/0014 , A61K47/10 , A61K47/20 , A61K47/34 , A61K47/38 , B01F7/00008 , B01F7/164 , B01F15/00012 , B01F15/00071 , B01F15/02 , B01F15/06
摘要： Provided according to some embodiments of the invention are methods of manufacturing a pharmaceutical composition. In some embodiments, such methods include homogenizing at a first excipient composition that includes a viscosity agent and at least one solvent to form a first premix composition; separately homogenizing at least one active pharmaceutical ingredient (API) and a second excipient composition to form a second premix composition; and combining the first premix composition and the second premix composition to form the composition. The pre-mixing of constituents may increase the stability of the API and provide uniformity of the dispersion of the constituents throughout the final topical composition.
摘要翻译：根据本发明的一些实施方案提供的是制备药物组合物的方法。在一些实施方案中，这些方法包括在包含粘度剂和至少一种溶剂的第一赋形剂组合物上均化以形成第一预混物组合物; 分别均化至少一种活性药物成分（API）和第二赋形剂组合物以形成第二预混物组合物; 以及组合第一预混组合物和第二预混物组合物以形成组合物。组分的预混合可以增加API的稳定性并提供组分在整个最终局部组合物中的分散体的均匀性。

9. 发明申请

WO00021652A1 DEVICE FOR MIXING TWO PASTY MATERIALS, ESPECIALLY FOR MIXING A DENTAL IMPRESSION MATERIAL WITH A CATALYST MATERIAL 审中-公开
标题翻译： DEVICE混合两种糊状物质，特别是用于混合牙科印模与催化剂MASS
公开(公告)号：WO00021652A1
公开(公告)日：2000-04-20
申请号：PCT/EP1999/007703
申请日：1999-10-14
IPC分类号： A61C9/00 , B01F7/00 , B01F13/00 , B01F15/00 , B05C17/005
CPC分类号： B05C17/00553 , A61C5/64 , A61C9/0026 , B01F7/00008 , B01F7/00141 , B01F13/002 , B01F2215/0039 , B05C17/00506 , B05C17/00516 , B05C17/00583 , B05C17/00586
摘要： The invention relates to device for mixing two pasty materials, especially a dental impression material with a catalyst material. Said device is fitted with a housing (42) having a substantially cylindrical section (44) with two radial inlets (68, 70) for both pasty materials on the back end of said section and an outlet (52) for the mixed pasty materials on the front end of the cylindrical section (44). The inventive device also includes a driveable mixing shaft (38) extending through the cylindrical section (44) and rotationally mounted in the housing (42). The mixing shaft (38) has a plurality of rigid mixing elements (74) spaced from an axis (72) for mixing both pasty materials as they pass through the cylindrical section (44) of the housing (42). The mixing shaft (38) has at least one deflecting element (80) in the area of the inlets (68, 70) for supporting transport in axial direction of the pasty material entering the cylindrical section (44) of the housing (42) through the inlets (68, 70), wherein the at least one deflecting element (80) has a deflecting surface (82) extending around the axis (72) and which is inclined in relation to the radial plane of said axis (72).
摘要翻译：两个糊状物质，特别是牙印模材料混合有催化剂材料的设备上设置有一个外壳（42）在其后端为具有带有两个径向入口开口（68，70）大致管状部分（44）具有两个糊状材料，并在所述管状部分（44）的前端，用于将混合糊状物质的出口（52），和延伸穿过所述管状部分（44）可驱动的混合器轴（38）和在壳体（42 ）可旋转地安装。混合器轴（38）通过投影为两种粘稠物质混合，当这些穿过壳体（42）的管状部分（44）刚性混合元件（74）的轴（72）具有多个。混合器轴（38）具有在所述入口开口的水平（68，70）的至少一个偏转元件（80），以支持通过进入所述壳体的所述管状部分（44）的入口开口（68，70）传送（42）的糊状物质成轴向上，其特征在于，倾斜地延伸到延伸偏转面（82）的轴线（72）的径向平面中的至少一个偏转元件（80）绕所述轴线（72）。

10. 发明申请

WO1997022239A1 IMPROVED SHARPENED BLADE FOR ROTATING SCREW FEEDERS OF CUTTING-MIXING MACHINES 审中-公开
标题翻译：切割混合机旋转螺旋进料机的改进叶片
公开(公告)号：WO1997022239A1
公开(公告)日：1997-06-26
申请号：PCT/EP1996002784
申请日：1996-06-26
申请人： SEKO S.P.A. , LOPPOLI, Giuseppe
发明人： SEKO S.P.A.
IPC分类号： A01F29/00
CPC分类号： B01F7/00008 , A01F29/005 , A01K5/002 , B01F7/02 , B01F13/1041 , B01F2013/108 , B01F2215/0008
摘要： The invention discloses a blade (1; 10; 30) for rotating screw feeders (2) of cutting-mixing machines for fodder, grass silage and similar. It is made by a metal disk (3) having multiple sharp profiles (6) which are made by multiple hollows (7; 71; 75) obtained on the edge of the disk (3). Such hollows are able to give the perimeter of the disk a variable profile which realizes on the product under processing an aggressive dragging and cutting action, being the variable profile sharpened for all the length of its perimeter according to a triangular cross-section profile (22) so to make it sharp.
摘要翻译：本发明公开了一种用于旋转饲料，青贮饲料等的切割混合机的螺旋给料机（2）的叶片（1; 10; 30）。它由金属盘（3）制成，具有由在盘（3）的边缘上获得的多个空心（7; 71; 75）制成的多个锋利轮廓（6）。这样的中空部分能够给盘的周边带来可变的轮廓，该轮廓可以在正处理的产品上实现积极的拖拉和切割动作，根据三角形截面轮廓（22）可变轮廓对其周长的所有长度进行磨削），使其变得尖锐。

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