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1. 发明申请

WO2016145483A1 RESPIRATORY THERAPY APPARATUS AND METHOD 审中-公开
标题翻译：呼吸治疗装置及方法
公开(公告)号：WO2016145483A1
公开(公告)日：2016-09-22
申请号：PCT/AU2016/050177
申请日：2016-03-14
申请人： RESMED LIMITED
发明人： DENNIS, Clancy John , HOLLEY, Liam , MALOUF, Gordon Joseph , MARTIN, Dion Charles Chewe , WLODARCZYK, Peter
IPC分类号： A61M16/00
CPC分类号： A61M16/024 , A61M16/0003 , A61M16/0006 , A61M16/0051 , A61M16/0066 , A61M16/0069 , A61M16/06 , A61M16/0633 , A61M16/0666 , A61M16/107 , A61M16/16 , A61M16/208 , A61M2016/0027 , A61M2016/003 , A61M2016/0033 , A61M2205/15 , A61M2205/18 , A61M2205/3317 , A61M2205/3334 , A61M2205/3365 , A61M2205/3368 , A61M2205/3584 , A61M2205/502 , A61M2205/52 , A61M2205/581 , A61M2205/8206 , A61M2230/42 , A61M2230/46
摘要： A method, such as in a controller associated with a respiratory therapy device, determines whether high flow therapy is being used by a patient. The method may include determining whether a property of a flow of air being delivered by a respiratory therapy device along an air circuit to an unsealed patient interface contains a significant oscillation within a breathing rate frequency band. The method may also include generating, dependent on the determination, an indication of whether high flow therapy is being used by the patient.
摘要翻译：诸如在与呼吸治疗装置相关联的控制器中的方法确定患者是否正在使用高流量治疗。该方法可以包括确定呼吸治疗装置沿着空气回路向未密封的患者接口递送的空气流的性质是否包含在呼吸频率频带内的显着振荡。该方法还可以包括根据确定产生患者是否正在使用高流量治疗的指示。

2. 发明申请

WO2016132279A1 ENHANCEMENT OF SIMULTANEOUS ESTIMATION OF RESPIRATORY PARAMETERS VIA SUPERIMPOSED PRESSURE SIGNAL 审中-公开
标题翻译：通过超级压力信号同时估计呼吸参数的增强
公开(公告)号：WO2016132279A1
公开(公告)日：2016-08-25
申请号：PCT/IB2016/050807
申请日：2016-02-16
申请人： KONINKLIJKE PHILIPS N.V.
发明人： WANG, Dong , VICARIO, Francesco , KARAMOLEGKOS, Nikolaos , ALBANESE, Antonio , CHBAT, Nicolas Wadih
IPC分类号： A61M16/00
CPC分类号： A61M16/026 , A61M16/0063 , A61M2230/46
摘要： A ventilator system includes a ventilator (10) configured to deliver an air flow at positive pressure to a ventilated patient (12). A signal generator (50) is configured to generate a non-therapeutic pressure signal having amplitude less than the maximum positive pressure of the air flow delivered to the ventilated patient and having the highest frequency component of at least 0.5 Hz. A signal combiner (52) is configured to superimpose the non-therapeutic pressure signal on the air flow delivered to the ventilated patient. A ventilator monitor (44) is programmed to estimate respiratory system' s resistance R and compliance C and respiratory muscle pressure generated by the ventilated patient based on pressure and air flow measurements. The non-therapeutic pressure signal is effective to impart a signal component with frequencies beyond normal respiratory signal frequency range to the measured pressure and air flow, which improves the robustness of the estimation task.
摘要翻译：呼吸机系统包括通气机（10），其构造成将正压力的气流输送到通气患者（12）。信号发生器（50）被配置为产生幅度小于传送到通气患者的空气流的最大正压并且具有至少0.5Hz的最高频率分量的非治疗压力信号。信号组合器（52）被配置为将非治疗压力信号叠加在输送到通气患者的气流上。通气机监视器（44）被编程为基于压力和空气流量测量来估计通气患者产生的呼吸系统的阻力R和顺应性C和呼吸肌肉压力。非治疗压力信号有效地将具有超出正常呼吸信号频率范围的频率的信号分量赋予测量的压力和空气流量，这提高了估计任务的鲁棒性。

3. 发明申请

WO2016128846A1 SIMULTANEOUS ESTIMATION OF RESPIRATORY PARAMETERS BY REGIONAL FITTING OF RESPIRATORY PARAMETERS 审中-公开
标题翻译：通过呼吸参数的区域配置同时估计呼吸参数
公开(公告)号：WO2016128846A1
公开(公告)日：2016-08-18
申请号：PCT/IB2016/050115
申请日：2016-01-12
申请人： KONINKLIJKE PHILIPS N.V.
发明人： ALBANESE, Antonio , VICARIO, Francesco , WANG, Dong , KARAMOLEGKOS, Nikolaos , CHBAT, Nicolas Wadih
IPC分类号： A61M16/00 , A61B5/085 , A61B5/087
CPC分类号： A61M16/024 , A61B5/085 , A61B5/087 , A61B5/4836 , A61M16/0063 , A61M16/026 , A61M2016/0027 , A61M2016/0036 , A61M2205/3331 , A61M2205/3334 , A61M2205/50 , A61M2230/46 , G06F19/3481 , G16H40/63
摘要： A medical ventilator (10) performs a method including: receiving measurements of pressure of air inspired by or expired from a ventilated patient (12) operatively connected with the medical ventilator;receiving measurements of air flow into or out of the ventilated patient operatively connected with the medical ventilator;dividing a breath time interval into a plurality of fitting regions (60); and simultaneously estimating respiratory system's resistance and compliance or elastance, and respiratory muscle pressure in each fitting region by fitting to a time series of pressure and air flow samples in that fitting region. In one approach, the fitting includes parameterizing the respiratory muscle pressure by a continuous differentiable function, such as a polynomial function, over the fitting region.In another approach, the fitting is to an equation of motion of the lungs in each fitting region, while monotonicity constraints and inequalities bounding at least the respiratory muscle pressure P mus (t) and respiratory system's resistence R and compliance C are applied to the respiratory muscle pressure in each region.
摘要翻译：医疗呼吸机（10）执行一种方法，包括：接收由与医疗呼吸机可操作地连接的通气患者（12）启发或过期的空气的测量值;接收进入或流出通气患者的气流的测量，医疗呼吸机;将呼吸时间间隔分成多个配合区域（60）; 同时通过适应该装配区域中的压力和气流样本的时间序列来同时估计每个装配区域中呼吸系统的阻力和顺应性或弹性，以及呼吸肌肉压力。在一种方法中，拟合包括在拟合区域上通过连续可微函数（例如多项式函数）来参数化呼吸肌肉压力。另一种方法是拟合到每个拟合区域中肺的运动方程，而至少呼吸肌肉压力P mus（t）和呼吸系统的抵抗力R和顺应性C的单调性约束和不等式适用于每个区域的呼吸肌肉压力。

4. 发明申请

WO2016053119A1 A METHOD AND APPARATUS FOR THE CONTROLLED DELIVERY OF GASES 审中-公开
标题翻译：用于控制输送气体的方法和装置
公开(公告)号：WO2016053119A1
公开(公告)日：2016-04-07
申请号：PCT/NZ2015/050169
申请日：2015-10-05
申请人： AUT UNIVERSITY
发明人： WHITE, David Edward , BARTLEY, James Russell Frederick , CURRIE, Jonathan David , MAKINSON, Ian Douglas , MCAULEY, Alastair Edwin , NATES, Roy Jonathan
IPC分类号： A61M16/00
CPC分类号： A61M16/0066 , A61M16/0051 , A61M16/0069 , A61M16/024 , A61M16/0616 , A61M16/1005 , A61M16/204 , A61M16/209 , A61M2016/0027 , A61M2016/0036 , A61M2202/0208 , A61M2205/3334 , A61M2205/3344 , A61M2205/3375 , A61M2210/0618 , A61M2230/04 , A61M2230/10 , A61M2230/14 , A61M2230/46 , A61M2230/62 , A61M2230/63 , A61M2230/005
摘要： A method of controlled delivery of breathing gases is described the method comprising: applying breathing gas pressure within the first naris of a patient during inhalation; applying breathing gas pressure within the second naris of the patient during inhalation; applying breathing gas pressure within the first naris of the patient during exhalation; and applying breathing gas pressure within the second naris of the patient during exhalation, wherein the breathing gas pressure applied to the first naris during inhalation is higher than the gas pressure applied to the second naris during inhalation and the breathing gas inflow to the patient is substantially through the first naris during inhalation and wherein the breathing gas pressure applied to the first naris during exhalation is lower than the gas pressure applied to the second naris during exhalation and the gas outflow from the patient is substantially through the first naris during exhalation. An apparatus and system implementing the method is also described.
摘要翻译：描述了一种控制呼吸气体输送的方法，该方法包括：在吸入期间在患者的第一鼻孔内施加呼吸气体压力; 在吸入过程中在患者的第二个鼻孔内施加呼吸气体压力; 在呼气期间在患者的第一鼻孔内施加呼吸气体压力; 以及在呼气期间在患者的第二鼻孔内施加呼吸气体压力，其中在吸入期间施加到第一鼻孔的呼吸气体压力高于在吸入期间施加到第二鼻孔的气体压力，并且呼吸气体流入患者体内基本上通过吸入期间的第一鼻孔，并且其中在呼气期间施加到第一鼻孔的呼吸气体压力低于在呼气期间施加到第二鼻孔的气体压力，并且来自患者的气体流出基本上在呼气期间通过第一鼻孔。还描述了实现该方法的装置和系统。

5. 发明申请

WO2015104669A1 PATIENT-VENTILATOR ASYNCHRONY DETECTION 审中-公开
标题翻译：患者通气道异常检测
公开(公告)号：WO2015104669A1
公开(公告)日：2015-07-16
申请号：PCT/IB2015/050143
申请日：2015-01-08
申请人： KONINKLIJKE PHILIPS N.V.
发明人： TAMS, Carl , EULIANO, Neil , BANNER, Michael , GABRIELLI, Andrea
IPC分类号： A61M16/00 , A61B5/08 , A61B5/00
CPC分类号： A61M16/0069 , A61B5/085 , A61B5/087 , A61B5/4833 , A61M16/0051 , A61M16/026 , A61M16/161 , A61M2016/0021 , A61M2016/0027 , A61M2016/0036 , A61M2016/102 , A61M2016/103 , A61M2205/15 , A61M2205/3306 , A61M2205/3317 , A61M2205/3365 , A61M2205/3368 , A61M2205/3375 , A61M2205/502 , A61M2205/505 , A61M2205/52 , A61M2230/005 , A61M2230/46
摘要： Systems and methods for detecting asynchrony between a subject (106) and a ventilator (140) are based on analyzing respiratory parameters across multiple respiratory cycles. By determining the variability and/or correlation of one or more parameters related to respiratory timing (inhalation duration, exhalation duration, etc.) and/ or a combination of respiratory flow rate and respiratory pressure, asynchrony may be detected and/or predicted.
摘要翻译：用于检测受试者（106）和呼吸机（140）之间的异步的系统和方法是基于跨多个呼吸周期分析呼吸参数。通过确定与呼吸时间（吸入持续时间，呼气持续时间等）相关的一个或多个参数和/或呼吸流速与呼吸压力的组合的变化性和/或相关性，可以检测和/或预测不同步。

6. 发明申请

WO2014046590A1 SYSTEM FOR OPTIMAL MECHANICAL VENTILATION 审中-公开
标题翻译：最佳机械通风系统
公开(公告)号：WO2014046590A1
公开(公告)日：2014-03-27
申请号：PCT/SE2013/000162
申请日：2013-10-22
申请人： INNOTEK AB
发明人： JONSON, Björn
IPC分类号： A61M16/00 , A61B5/08
CPC分类号： A61B5/087 , A61B5/021 , A61B5/0836 , A61B5/14542 , A61B5/4836 , A61M16/0051 , A61M16/026 , A61M16/16 , A61M16/204 , A61M16/205 , A61M2016/0021 , A61M2016/0027 , A61M2016/0036 , A61M2016/0039 , A61M2016/0042 , A61M2016/103 , A61M2205/18 , A61M2205/3561 , A61M2205/3569 , A61M2205/3592 , A61M2205/50 , A61M2230/205 , A61M2230/30 , A61M2230/432 , A61M2230/46
摘要： The invention relates to a system for mechanical ventilation comprising transducers for measurement of airway flow rate, pressure and CO 2 and at least one computer that records and analysis the transducer signals. The operator defines physiological specified goals or accepts default values. Specified physiological goals relate to CO 2 exchange and to volumes and pressures so as to to minimise deleterious effects of ventilation. On the basis of physiological information about the respiratory system characterised according to the principle of volumetric capnography and lung mechanical parameters, the computer performs analytical calculations in order to identify one or more modes of ventilator operation leading to specified goals. Such a mode of operation is implemented manually or automatically in one or more steps. The physiological outcome of resetting is reported and an alarm is issued when the outcome deviates from expectations. The computer may perform repeated automatic measurements and repeat the resetting in order to reach and maintain a status of the patient coherent with specified goals.
摘要翻译：本发明涉及一种用于机械通气的系统，其包括用于测量气道流速，压力和二氧化碳的传感器以及记录和分析换能器信号的至少一台计算机。操作员定义生理指定目标或接受默认值。指定的生理目标涉及二氧化碳交换和体积和压力，以尽量减少通气的有害影响。在根据体积二氧化碳图和肺机械参数原理表征的呼吸系统的生理信息的基础上，计算机进行分析计算，以识别导致指定目标的一种或多种呼吸机操作模式。这种操作模式在一个或多个步骤中手动或自动地实现。报告重生的生理结果，当结果偏离预期时发出警报。计算机可以执行重复的自动测量并重复重置，以便达到和维持与指定目标一致的患者的状态。

7. 发明申请

WO2013068918A1 SYSTEMS AND METHODS FOR INTRA-PULMONARY PERCUSSIVE VENTILATION INTEGRATED IN A VENTILATOR 审中-公开
标题翻译：集成在通风器内的脉冲式通气通风系统和方法
公开(公告)号：WO2013068918A1
公开(公告)日：2013-05-16
申请号：PCT/IB2012/056184
申请日：2012-11-06
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V.
发明人： GARDE, Smita , AHMAD, Samir
IPC分类号： A61M16/00
CPC分类号： A61M16/0069 , A61B5/0823 , A61B5/091 , A61M16/00 , A61M16/0006 , A61M16/0051 , A61M16/0066 , A61M16/024 , A61M16/06 , A61M16/161 , A61M16/202 , A61M16/205 , A61M16/208 , A61M2016/0018 , A61M2016/0027 , A61M2016/0036 , A61M2205/18 , A61M2205/3303 , A61M2205/3365 , A61M2205/3584 , A61M2205/502 , A61M2205/505 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2230/005 , A61M2230/43 , A61M2230/46
摘要： System and methods for providing respiratory therapy include predetermined and/or automatically determined perturbations of levels of pressure, flow, and/or other gas parameters integrated and/or combined with a supplied pressurized flow of breathable gas for a subject. The perturbations are intended to improve secretion management through intra-pulmonary percussive ventilation integrated with ventilation therapy.
摘要翻译：用于提供呼吸治疗的系统和方法包括与所供应的用于受试者的可呼吸气体的加压气流集成和/或组合的预定和/或自动确定的压力水平，流量和/或其他气体参数的扰动。扰动旨在通过与通气治疗相结合的肺内打击式通气改善分泌物管理。

8. 发明申请

WO2011027242A1 SYSTEM AND METHOD FOR QUANTIFYING LUNG COMPLIANCE IN A SELF-VENTILATING SUBJECT 审中-公开
标题翻译：用于量化自我通气主题中的肺顺应性的系统和方法
公开(公告)号：WO2011027242A1
公开(公告)日：2011-03-10
申请号：PCT/IB2010/053490
申请日：2010-07-30
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , BALOA WELZIEN, Leonardo Alberto , O'CONNOR, Nathan Francis
发明人： BALOA WELZIEN, Leonardo Alberto , O'CONNOR, Nathan Francis
IPC分类号： A61B5/08 , A61M16/00
CPC分类号： A61B5/08 , A61M16/0051 , A61M16/024 , A61M16/16 , A61M16/161 , A61M2016/0021 , A61M2016/0024 , A61M2016/0036 , A61M2205/332 , A61M2205/3365 , A61M2205/505 , A61M2230/42 , A61M2230/43 , A61M2230/46
摘要： The lung compliance of a subject that is at least partially self-ventilating is determined. The quantification of lung compliance may be an estimation, a measurement, and/or an approximate measurement. The quantification of lung compliance may be enhanced over conventional techniques and/or systems for quantifying lung compliance of self-ventilating subjects in the lung compliance may be quantified relatively accurately without an effort belt or other external sensing device that directly measures diaphragmatic muscle pressure, and without requiring the subject to manually control diaphragmatic muscle pressure. Quantification of lung compliance may be a useful tool in evaluating the health of the subject, including detection of fluid retention associated with developing acute congestive heart failure.
摘要翻译：确定至少部分自通气的受试者的肺顺应性。肺顺应性的量化可以是估计，测量和/或近似测量。与常规技术和/或用于定量肺自我通气对象的肺顺应性的系统相比，肺顺应性的量化可以得到增强，并且可以相对准确地量化肺顺应性，而不需要直接测量膈肌压力的努力带或其他外部感测装置，以及而不需要受试者手动控制膈肌压力。量化肺顺应性可能是评估受试者健康的有用工具，包括检测与发展急性充血性心力衰竭相关的体液潴留。

9. 发明申请

WO2010070497A1 SYSTEM AND METHOD FOR TREATING LUNG DISEASE USING POSITIVE PRESSURE AIRWAY SUPPORT 审中-公开
标题翻译：使用正压气道支持治疗肺疾病的系统和方法
公开(公告)号：WO2010070497A1
公开(公告)日：2010-06-24
申请号：PCT/IB2009/055258
申请日：2009-11-21
申请人： KONINKLIJKE PHILIPS ELECTRONICS, N.V. , MECHLENBURG, Douglas
发明人： MECHLENBURG, Douglas
IPC分类号： A61M16/00
CPC分类号： A61M16/202 , A61B5/085 , A61B5/087 , A61M11/00 , A61M15/00 , A61M16/0006 , A61M16/0069 , A61M16/026 , A61M2016/0039 , A61M2230/46
摘要： A method of treating lung disease, such as asthma or COPD, is provided that includes delivering positive pressure support to an airway of a patient during a plurality of respiratory cycles, and automatically varying a pressure level of the positive pressure support during at least a portion of the inspiratory phase of the patient in a number of the respiratory cycles.
摘要翻译：提供了治疗肺部疾病如哮喘或COPD的方法，其包括在多个呼吸循环期间向患者的气道递送正压力支持，并且在至少一部分期间自动改变正压支持体的压力水平在多个呼吸周期中患者的吸气阶段。

10. 发明申请

WO2007092492A2 SYSTEMS AND METHODS FOR PROCESSING PULMONARY FUNCTION DATA 审中-公开
标题翻译：用于处理脉搏函数数据的系统和方法
公开(公告)号：WO2007092492A2
公开(公告)日：2007-08-16
申请号：PCT/US2007/003243
申请日：2007-02-06
申请人： GOLDMAN, Michael, David
发明人： GOLDMAN, Michael, David
CPC分类号： A61B5/0806 , A61B5/08 , A61B5/411 , A61M16/0006 , A61M16/1055 , A61M16/106 , A61M2205/7518 , A61M2230/46
摘要： The invention provides improved methods for analysis of data obtained from certain pulmonary testing procedures, in particular from whole body plethysmography or from the forced oscillation technique. The improved computer-implemented methods automatically recognize data that has been distorted by patient behaviors during testing. This invention also provides computer systems that interface to devices that perform whole body plethysmography and/or the forced oscillation technique and automatically execute the methods of this invention. This invention also provides for distribution of software that causes computer systems to perform the methods of this invention.
摘要翻译：本发明提供了用于分析从某些肺部测试程序，特别是全身体积描记法或强制振荡技术获得的数据的改进方法。改进的计算机实现的方法自动识别在测试期间被患者行为扭曲的数据。本发明还提供了与执行全身体积描记法和/或强制振荡技术并自动执行本发明方法的装置相连接的计算机系统。本发明还提供使计算机系统执行本发明的方法的软件的分发。

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