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    • 6. 发明申请
    • INJECTION DEVICE WITH A NEEDLE CANNULA
    • 注射装置与针肛门
    • WO2015062845A1
    • 2015-05-07
    • PCT/EP2014/071746
    • 2014-10-10
    • NOVO NORDISK A/S
    • BENGTSSON, HenrikEILERTSEN, LarsJENSEN, Casper BoKIRK, Frederik Kaae
    • A61M5/00A61M5/32A61M5/24
    • A61M5/001A61M5/24A61M5/2466A61M5/3204A61M5/3213A61M5/326A61M2005/2474A61M2005/3115A61M2005/3121A61M2005/3267
    • The present invention relates to an injection device for injecting a pharmaceutical liquid drug containing a preservative. The injection device comprises a housing (1) supporting a cartridge (20) having an interior chamber (21) holding the pharmaceutical preservative containing liquid drug to be injected, and a needle cannula (10) having a front part (11) and a back part (12), which back part (12) is adapted to be in liquid communication with the interior chamber (21) of the cartridge (20). The injection device is further provided with a telescopic needle covering shield (30) which distally is provided with a reservoir (31) which holds a liquid containing the same preservatives as in the pharmaceutical preservative containing liquid drug contained in the interior chamber of the cartridge. The telescopic needle covering shield (30) is telescopic movable in relation to the needle cannula (10) by a first resilient member between a first position and a second position. In the first position, the tip (13) of the front part (11) of the needle cannula (10) is maintained inside the reservoir (31), and in the second position, the tip (13) of the front part (11) of the needle cannula (10) is located outside the reservoir (31) and distally to the reservoir (31). The tip (13) of the needle cannula (10) is thus cleaned by the preservatives in the reservoir (31) between subsequent injections.
    • 本发明涉及一种用于注射含有防腐剂的药物液体药物的注射装置。 注射装置包括支撑具有保持含有要注射的液体药物的药物防腐剂的内部腔室(21)的药筒(20)的壳体(1)和具有前部(11)和背部 部分(12),该后部部分(12)适于与药筒(20)的内部腔室(21)液体连通。 注射装置还设置有伸缩针覆盖屏蔽件(30),其在远端设置有储存器(31),该储存器保持含有与包含在药筒的内部腔室中的液体药物中的药用防腐剂相同的防腐剂的液体。 伸缩针覆盖屏蔽(30)可通过第一弹性构件在第一位置和第二位置之间相对于针管(10)伸缩移动。 在第一位置,针套管(10)的前部(11)的尖端(13)保持在储存器(31)的内部,并且在第二位置,前部(11)的尖端(13) )套管(10)的外侧位于储存器(31)的外部并且远离储存器(31)。 针管(10)的尖端(13)因此在后续注射之间由储存器(31)中的防腐剂清洁。
    • 7. 发明申请
    • AUTOMATIC APPLICATOR FOR LIQUID PHARMACEUTICAL PREPARATIONS, PARTICULARLY FOR INSULIN
    • 液体药物制剂自动化设备,特别适用于胰岛素
    • WO2010089418A3
    • 2010-10-28
    • PCT/EP2010054128
    • 2010-03-29
    • COPERNICUS SP Z O OSTEFANSKI ADAM
    • STEFANSKI ADAM
    • A61M5/315
    • A61M5/31543A61M5/20A61M5/24A61M5/31535A61M5/31551A61M5/31553A61M5/31555A61M5/31583A61M2005/202A61M2005/2407A61M2005/2488A61M2005/3115
    • An automatic applicator for liquid pharmaceutical preparations, particularly for insulin, more particularly for multiple injection application of set doses of a medicine from an exchangeable container, comprising a body housing (1) connected to a housing (2) of an exchangeable container with a medicine, particularly insulin, having a plunger (12), suitable for expelling the medicine, the said plunger (12) being displaced only linearly by means of an integrated driving unit, suitable for immobilising, driving, leading linearly and blocking rotation of the said plunger (12), driven via a double action clutch, by a tensioning spring (15) situated in the body housing (1), the said spring (15) tensioned by a rotary hand-dose-setting ring (3) via the same double action clutch unit, wherein the said driving unit is activated by a trigger unit (13) and a dose is indicated by an indicating arrangement, according to the present invention is characterised in that it comprises at least one block key (5.6) placed in the upper part of the ratchet barrel (5), collaborating with at least one key (1.3) placed in the internal part of the cylindrical body housing (1).
    • 一种用于液体药物制剂,特别是用于胰岛素的自动施用器,更特别地,用于多次注射施用来自可更换容器的药物剂量的设备,包括:主体壳体(1),其连接到具有药物的可更换容器的壳体(2) 特别是胰岛素,具有适于排出药物的柱塞(12),所述柱塞(12)仅通过集成驱动单元线性地移位,适合于固定,驱动,引导和阻止所述柱塞的旋转 (12)通过双作用离合器驱动,通过位于主体壳体(1)中的张紧弹簧(15)驱动,所述弹簧(15)由旋转手动剂量设定环(3)通过相同的双重 动作离合器单元,其中根据本发明,所述驱动单元由触发单元(13)激活并且剂量由指示装置指示,其特征在于,其包括至少一个块k (5.6)放置在棘轮筒(5)的上部,与放置在圆柱体壳体(1)的内部中的至少一个键(1.3)协作。
    • 9. 发明申请
    • HAND-ACTUATED SYRINGE WITH VACUUM CHAMBER FOR AUTO REFILL
    • 手动执行自动清洗真空泵
    • WO2010091132A1
    • 2010-08-12
    • PCT/US2010/023125
    • 2010-02-04
    • MALLINCKRODT INC.MARTZ, Kevin, R.
    • MARTZ, Kevin, R.
    • A61M5/20
    • A61M5/204A61J1/10A61M5/007A61M5/1782A61M39/24A61M2005/3115
    • A hand-activated syringe (14) is disclosed that uses a vacuum to retract a plunger (54) of the syringe (14) to draw fluid into a syringe body (18). A first seal (76) with the plunger (54) and a second seal (64) with the plunger (54) define a vacuum chamber (82). The spacing between the first seal (76) and the second seal (64) changes in response to the plunger (54) moving relative to the syringe body (18). Advancing the plunger (54) in a direction associated with a discharge stroke creates or increases a vacuum within the vacuum chamber (82) by increasing a spacing between the first seal (76) and the second seal (64). This vacuum thereafter may be used to retract the plunger (54) by decreasing a spacing between the first seal (76) and the second seal (64), and to thereby draw fluid into the syringe (14) from a fluid source (86).
    • 公开了一种手动激活的注射器(14),其使用真空来缩回注射器(14)的柱塞(54)以将流体抽入注射器主体(18)。 具有柱塞(54)的第一密封件(76)和具有柱塞(54)的第二密封件(64)限定真空室(82)。 第一密封件(76)和第二密封件(64)之间的间隔响应于相对于注射器主体(18)移动的柱塞(54)而改变。 在与排放冲程相关联的方向上推动柱塞(54)通过增加第一密封件(76)和第二密封件(64)之间的间隔来产生或增加真空室(82)内的真空。 此后的这种真空可以用于通过减小第一密封件(76)和第二密封件(64)之间的间隔来缩回柱塞(54),从而从流体源(86)将流体引入注射器(14) 。