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1. 发明申请

WO2018220393A1 AMYLIN PEPTIDES 审中-公开
公开(公告)号：WO2018220393A1
公开(公告)日：2018-12-06
申请号：PCT/GB2018/051503
申请日：2018-06-01
申请人： UNIVERSITY OF LANCASTER
发明人： OBASSE, Idira , ALLSOP, David
IPC分类号： C07K14/575 , A61K38/17 , A61K38/22 , C07K14/47
CPC分类号： C07K14/575 , A61K38/00 , A61K38/1716 , A61K38/22 , C07K14/4711
摘要： The present invention relates to modified peptides which are designed to inhibit amylin aggregation and which may be used therapeutically for treating diseases such a type-2 diabetes. There is also provides pharmaceutical formulations comprising the modified peptides, as well as methods of treatment.

2. 发明申请

WO2013171474A2 ANOMALOUS SYSTEM STATE IDENTIFICATION 审中-公开
标题翻译：异常系统状态识别
公开(公告)号：WO2013171474A2
公开(公告)日：2013-11-21
申请号：PCT/GB2013/051237
申请日：2013-05-14
申请人： UNIVERSITY OF LANCASTER , ANGELOV, Plamen
发明人： ANGELOV, Plamen
IPC分类号： G06F11/07 , G06F11/30 , G06N7/00
CPC分类号： G06F21/56 , G06F11/0751 , G06F11/3055 , G06N7/005

3. 发明申请

WO2003069332A2 DETECTION AND/OR MONITORING OF SYNUCLEIN-RELATED DISEASES 审中-公开
标题翻译：检测和/或监测综合征相关疾病
公开(公告)号：WO2003069332A2
公开(公告)日：2003-08-21
申请号：PCT/GB2003/000677
申请日：2003-02-14
申请人： THE UNIVERSITY OF LANCASTER , ALLSOP, David , EL-AGNAF, Omar, M., A. , SALEM, Sultan, A.
发明人： ALLSOP, David , EL-AGNAF, Omar, M., A. , SALEM, Sultan, A.
IPC分类号： G01N33/48
CPC分类号： G01N33/57484 , G01N33/6896 , G01N2800/52
摘要： The invention provides a method of diagnosing a synucleinopathy in a patient and also a method monitoring the effectiveness of a therapeutic agent that has been administered to a patient for the purpose of treating a synucleinopathy. The method comprises analysing a non-cerebral body fluid sample taken from the patient for the presence and/or amount of a synuclein in said sample.The synuclein may be an aggregated synuclein.
摘要翻译：本发明提供了诊断患者的突触核蛋白病的方法，还提供了监测已经施用于患者以治疗突触核蛋白病的治疗剂的有效性的方法。该方法包括分析从患者获取的非脑体液样品中所述样品中存在和/或数量的突触核蛋白。突触核蛋白可以是聚集的突触核蛋白。

4. 发明申请

WO1990013927A1 ANTENNA SYSTEM 审中-公开
标题翻译：天线系统
公开(公告)号：WO1990013927A1
公开(公告)日：1990-11-15
申请号：PCT/GB1990000688
申请日：1990-05-03
申请人： THE UNIVERSITY OF LANCASTER , LAZARUS, Max, Jonathan
发明人： THE UNIVERSITY OF LANCASTER
IPC分类号： H01Q19/08
CPC分类号： H01Q19/08
摘要： An antenna system for use in transmitting and receiving beams of electromagnetic waves of frequencies up to and including the sub-millimetre region of the spectrum comprises a horn (1) and a lens arrangement (4, 5) all of which are of a dielectric material. The feeder (1) may be solid or hollow and may be moulded integrally with a lens. Preferred dielectric materials are low loss media such as polyethylene. The antenna is cheap and easy to manufacture and has efficiency at least as good as quality precision metal antennae.
摘要翻译：一种天线系统，用于发射和接收频谱直到并包括频谱的亚毫米范围的频率的波束，包括喇叭（1）和透镜装置（4,5），所有这些都是电介质材料。进料器（1）可以是实心的或中空的，并且可以与透镜一体地模制。优选的介电材料是低损耗介质如聚乙烯。天线便宜，易于制造，效率至少与质量精密金属天线一样好。

5. 发明申请

WO1989012766A1 SUSPENSION SYSTEM 审中-公开
标题翻译：悬挂系统
公开(公告)号：WO1989012766A1
公开(公告)日：1989-12-28
申请号：PCT/GB1989000703
申请日：1989-06-22
申请人： THE UNIVERSITY OF LANCASTER , FRENCH, Michael, Joseph
发明人： THE UNIVERSITY OF LANCASTER
IPC分类号： F16F09/04
CPC分类号： B60G17/0165 , B60G17/0155 , B60G17/0485 , B60G2202/152 , B60G2400/102 , B60G2400/51222 , B60G2500/22 , B60G2600/02 , B60G2600/26
摘要： A suspension system (e.g. for a vehicle) comprises a gas spring (1) and a mass (e.g. the vehicle body) mounted on the spring for damped oscillating movement. Gas spring has a first gas chamber (2) of variable volume which is compressible and expansible by oscillations of the spring, and a second rigid gas chamber (3) which communicates directly with the first chamber (1) via a rapidly openable and closable valve (5, 6). The system incorporates means (11, 12) for detecting a function of changing compression of the first chamber (1). These detection means are operatively associated with the valve (4, 5) to affect closure or opening thereof when the function passes through predetermined values. Opening of the valve when there is a pressure difference thereacross serves to dissipate energy in the subsequent equalising process, and the changes in stiffness of the spring serve to de-tune the system.
摘要翻译：悬架系统（例如，用于车辆）包括气弹簧（1）和安装在弹簧上的用于阻尼振荡运动的质量块（例如车体）。气弹簧具有可变体积的第一气室（2），其通过弹簧的振荡可压缩和膨胀;以及第二刚性气室（3），其通过快速打开和关闭的阀门直接与第一腔室（1）连通（5,6）。该系统包括用于检测改变第一腔室（1）的压缩功能的装置（11,12）。当功能通过预定值时，这些检测装置可操作地与阀（4,5）相关联，以影响其关闭或打开。当阀门有压力差时，阀门的打开用于在随后均衡过程中耗散能量，弹簧的刚度变化用于使系统失调。

6. 发明申请

WO2022269248A1 VIRUS ATTENUATION 审中-公开
公开(公告)号：WO2022269248A1
公开(公告)日：2022-12-29
申请号：PCT/GB2022/051579
申请日：2022-06-21
申请人： UNIVERSITY OF LANCASTER
发明人： MUNIR, Muhammad
IPC分类号： A61K39/17 , C07K14/005 , C12N7/04 , C12N15/86 , A61K2039/5254 , A61K39/12 , C12N2760/18121 , C12N2760/18122 , C12N2760/18134 , C12N2760/18143 , C12N2760/18151 , C12N2760/18162 , C12N2800/22 , C12N2800/24
摘要： The present disclosure relates to paramyxoviruses, in particular attenuated avian avulaviruses (para, ortho and meta), mutated and genetically modified forms, as well as a vaccine formulation comprising an attenuated avian avulavirus and uses/methods of use thereof.

7. 发明申请

WO2021255426A1 SEMICONDUCTOR STRUCTURES 审中-公开
公开(公告)号：WO2021255426A1
公开(公告)日：2021-12-23
申请号：PCT/GB2021/051485
申请日：2021-06-15
申请人： UNIVERSITY OF LANCASTER
发明人： CARRINGTON, Peter , DELLI, Evangelia
IPC分类号： H01L21/20 , H01L21/02381 , H01L21/02458 , H01L21/02463 , H01L21/02466 , H01L21/02507 , H01L21/0254 , H01L21/02543 , H01L21/02546 , H01L21/02549
摘要： A semiconductor device comprises a substrate, one or more first III- semiconductor layers, and a plurality of superlattice structures between the substrate and the one or more first layers. The plurality of superlattice structures comprises an initial superlattice structure and one or more further superlattice structures between the initial superlattice structure and the one or more first layers. The plurality of superlattice structures is configured such that a strain-thickness product of semiconductor layer pairs in each superlattice structure of the one or more further superlattice structures is greater than or equal to a strain-thickness product of semiconductor layer pairs in superlattice structure(s) of the plurality of superlattice structures between that superlattice structure and the substrate. The plurality of superlattice structures is also configured such that a strain-thickness product of semiconductor layer pairs in at least one of the one or more further superlattice structures is greater than a strain-thickness product of semiconductor layer pairs in the initial superlattice structure.

8. 发明申请

WO2019012276A1 SINGLE PHOTON DETECTOR 审中-公开
公开(公告)号：WO2019012276A1
公开(公告)日：2019-01-17
申请号：PCT/GB2018/051972
申请日：2018-07-11
申请人： UNIVERSITY OF LANCASTER
发明人： MARSHALL, Andrew , CRAIG, Adam
IPC分类号： H01L31/107
CPC分类号： H01L31/1075
摘要： A photon detector such as an avalanche photodiode or a single photon avalanche photodiode comprises a semiconductor device comprising an absorber region and a multiplication region. The multiplication region comprises aluminium arsenide antimonide (AIAsSb) and/or aluminium gallium arsenide antimonide (AIGaAsSb). The absorption region comprises indium gallium arsenide antimonide (InGaAsSb) and/or indium arsenide antimonide (InAsSb).

9. 发明申请

WO2013084004A1 NEUTRON SOURCE 审中-公开
标题翻译： NEUTRON源
公开(公告)号：WO2013084004A1
公开(公告)日：2013-06-13
申请号：PCT/GB2012/053060
申请日：2012-12-07
申请人： UNIVERSITY OF LANCASTER , UNIVERSITY OF MANCHESTER , SEVIOUR, Rebecca , BAILEY, Ian , OWEN, Hywel
发明人： SEVIOUR, Rebecca , BAILEY, Ian , OWEN, Hywel
IPC分类号： G21G4/02 , H05H3/00 , H05H3/06
CPC分类号： G21G4/02 , H05H3/06 , H05H6/00
摘要： A neutron source (200), method of generating neutrons and target stage (206) are described. The neutron source includes a source of deuterons (218), an accelerator (230) and a target stage including an oxygen containing target (254) and a moderator (292). The accelerator is in communication with the source and is operable to accelerate deuterons from the source of deuterons and output a deuteron beam (282) of at least 2 MeV. The target stage is in communication with an output of the accelerator, and the oxygen containing target (286) is positioned to be impacted by the deuteron beam output by the accelerator and generate neutrons which are moderated to generate an output neutron beam (294). The target material can be solid carbon dioxide. This can provide a compact neutron source particularly suited to industrial and commercial applications such as isotope production.
摘要翻译：描述了中子源（200），产生中子的方法和目标阶段（206）。中子源包括氘核（218）源，加速器（230）和包括含氧靶（254）和主体（292）的目标阶段。加速器与源相通，并且可操作地加速来自氘核的氘核并输出至少2MeV的氘核束（282）。目标阶段与加速器的输出端连通，并且含氧目标（286）被定位成受到由加速器输出的氘核束影响，并产生中和以产生输出中子束（294）。目标材料可以是固体二氧化碳。这可以提供特别适用于工业和商业应用如同位素生产的紧凑型中子源。

10. 发明申请

WO2012042203A4 METHOD OF METAL DEPOSITION 审中-公开
公开(公告)号：WO2012042203A4
公开(公告)日：2012-04-05
申请号：PCT/GB2011/001402
申请日：2011-09-28
申请人： UNIVERSITY OF LANCASTER , BOXALL, Colin , BROMLEY, Michael
发明人： BOXALL, Colin , BROMLEY, Michael
IPC分类号： C23C18/18 , C23C18/16 , C23C18/31 , C23C18/44
摘要： A method of forming a metal layer on an electrically insulating substrate comprises depositing a photocatalyst layer onto the substrate and depositing a mask layer comprising voids on the substrate, such as a layer of latex microparticles with voids between them, to give an open pore structure to the mask. An electroless plating solution is then provided on the photocatalyst layer, and the photocatalyst layer and electroless plating solution are illuminated with actinic radiation whereby deposition of metal from the electroless plating solution to form a metal layer on the photocatalyst layer is initiated whereby the metal deposits in the voids of the mask layer. The mask layer is subsequently removed to leave a porous metal layer on the substrate. The method allows for deposition of porous metal films with controlled thickness and excellent adhesion onto electrically insulating substrates. The method is suitable for providing metal layers with controlled, regular porosity.

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