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1. 发明申请

WO2009134672A1 GENERATION OF A COMPUTERIZED BONE MODEL REPRESENTATIVE OF A PRE-DEGENERATED STATE AND USEABLE IN THE DESIGN AND MANUFACTURE OF ARTHROPLASTY DEVICES 审中-公开
标题翻译：预处理状态的计算机骨架模型代表的产生并且可用于ARTHROPLASTY设备的设计和制造
公开(公告)号：WO2009134672A1
公开(公告)日：2009-11-05
申请号：PCT/US2009/041519
申请日：2009-04-23
申请人： OTISMED CORPORATION , PARK, Ilwhan , CHI, Charlie, W. , HOWELL, Stephen, M.
发明人： PARK, Ilwhan , CHI, Charlie, W. , HOWELL, Stephen, M.
IPC分类号： A61F5/00
CPC分类号： A61B34/10 , A61B17/15 , A61B17/154 , A61B17/155 , A61B17/157 , A61B2034/102 , A61B2034/105 , A61B2034/108 , A61F5/00 , G06F17/50 , G06F19/00 , G06F19/321 , G06T17/00 , G16H50/50
摘要： A method of generating a computerized bone model representative of at least a portion of a patient bone in a pre-degenerated state, including generating at least one image of the patient bone in a degenerated state; identifying a reference portion associated with a generally non-degenerated portion of the patient bone; identifying a degenerated portion associated with a generally degenerated portion of the patient bone; and using information from at least one image associated with the reference portion to modify at least one aspect associated with at least one image associated the generally degenerated portion. The method may further include employing the model in defining manufacturing instructions for the manufacture of a customized arthroplasty jig. A customized arthroplasty jig may be manufactured according to the above-described method and is configured to facilitate a prosthetic implant restoring a patient joint to a natural alignment.
摘要翻译：一种产生代表患者骨骼的至少一部分的预退化状态的计算机化骨模型的方法，包括产生处于退化状态的患者骨骼的至少一个图像; 识别与患者骨的通常非退化部分相关联的参考部分; 识别与患者骨的大致退化部分相关联的退化部分; 以及使用与所述参考部分相关联的至少一个图像的信息来修改与与所述大致退化部分相关联的至少一个图像相关联的至少一个方面。该方法还可以包括在定义用于制造定制的关节成形术夹具的制造说明书中使用该模型。可以根据上述方法制造定制的关节造形术夹具，并且构造成便于将患者关节恢复到自然对准的假体植入物。

2. 发明申请

WO2009111213A2 HIP RESURFACING SURGICAL GUIDE TOOL 审中-公开
标题翻译： HIP修复手术指南
公开(公告)号：WO2009111213A2
公开(公告)日：2009-09-11
申请号：PCT/US2009/034967
申请日：2009-02-24
申请人： OTISMED CORPORATION , PARK, Ilwhan , KOEHLE, Michael , DEVEZA, Lorenzo, R.
发明人： PARK, Ilwhan , KOEHLE, Michael , DEVEZA, Lorenzo, R.
IPC分类号： A61B17/58
CPC分类号： A61B34/10 , A61B17/175 , A61B2017/568 , A61B2034/102 , A61B2034/105 , A61B2034/107 , A61B2034/108 , A61F2/3603 , A61F2/3609 , A61F2002/30878 , A61F2002/505 , B33Y80/00 , G05B19/41885 , Y02P90/14 , Y02P90/20
摘要： Disclosed herein is a tool for guiding a drill hole along a central axis of a femur head and neck for preparation of a femur head that is the subject of a hip resurfacing surgery. In one embodiment, the tool includes a mating region and a guide hole. The mating region is configured to matingly receive a predetermined surface of the femur. The mating region and guide hole are positionally correlated or referenced with each other such that when the mating region matingly receives the predetermined surface of the femur, the guide hole will be generally coaxial with a central axis extending through the femur head and the femur neck.
摘要翻译：本文公开了一种用于沿着股骨头部和颈部的中心轴线引导钻孔的工具，用于准备作为髋关节表面置换手术的对象的股骨头。在一个实施例中，工具包括配合区域和引导孔。配合区域被配置成配合地接收股骨的预定表面。配合区域和引导孔在位置上相互关联或相互参照，使得当配合区域配合地接收股骨的预定表面时，引导孔将与延伸穿过股骨头部和股骨颈部的中心轴线大致同轴。

3. 发明申请

WO2009134620A2 SYSTEM AND METHOD FOR IMAGE SEGMENTATION IN GENERATING COMPUTER MODELS OF A JOINT TO UNDERGO ARTHROPLASTY 审中-公开
标题翻译：用于图像分割的系统和方法，用于生成联合到下面的脑电图的计算机模型
公开(公告)号：WO2009134620A2
公开(公告)日：2009-11-05
申请号：PCT/US2009/040629
申请日：2009-04-15
申请人： OTISMED CORPORATION , PAVLOVSKAIA, Elena , SARVA, Venkata, S.
发明人： PAVLOVSKAIA, Elena , SARVA, Venkata, S.
IPC分类号： G06K9/00 , G06K9/36
CPC分类号： G06K9/00 , A61B17/155 , A61B17/157 , A61B2034/102 , G06K9/32 , G06K9/48 , G06K2009/484 , G06K2209/055
摘要： Systems and methods for image segmentation in generating computer models of a joint to undergo arthroplasty are disclosed. Some embodiments may include a method of partitioning an image of a bone into a plurality of regions, where the method may include obtaining a plurality of volumetric image slices of the bone, generating a plurality of spline curves associated with the bone, verifying that at least one of the plurality of spline curves follow a surface of the bone, and creating a 3D mesh representation based upon the at least one of the plurality of spline curve.
摘要翻译：公开了用于生成关节成形术的关节的计算机模型中的图像分割的系统和方法。一些实施例可以包括将骨骼的图像分割成多个区域的方法，其中该方法可以包括获得骨的多个体积图像切片，产生与骨骼相关联的多个样条曲线，验证至少多个样条曲线中的一个跟随着骨的表面，并且基于多个样条曲线中的至少一个来创建3D网格表示。

4. 发明申请

WO2009079118A1 SYSTEM AND METHOD FOR MANUFACTURING ARTHROPLASTY JIGS 审中-公开
标题翻译：用于制造青光眼的系统和方法
公开(公告)号：WO2009079118A1
公开(公告)日：2009-06-25
申请号：PCT/US2008/083125
申请日：2008-11-11
申请人： OTISMED CORPORATION , PARK, Ilwhan , HOWELL, Stephen, M.
发明人： PARK, Ilwhan , HOWELL, Stephen, M.
IPC分类号： A61B17/58 , A61B17/60 , A61F2/00
CPC分类号： A61B17/58 , A61B5/055 , A61B5/4514 , A61B5/4528 , A61B6/03 , A61B17/15 , A61B17/155 , A61B17/157 , A61B17/1703 , A61B17/1725 , A61B17/1739 , A61B17/1742 , A61B17/1764 , A61B34/10 , A61B2034/105 , A61B2034/108
摘要： Disclosed herein is a method of computer generating a three-dimensional surface model of an arthroplasty target region of a bone forming a joint. The method may include: generating two-dimensional images of at least a portion of the bone; generating an open-loop contour line along the arthroplasty target region in at least some of the two-dimensional images; and generating the three-dimensional model of the arthroplasty target region from the open-loop contour lines.
摘要翻译：本文公开了一种计算机产生形成关节的骨的关节成形术目标区域的三维表面模型的方法。该方法可以包括：产生骨的至少一部分的二维图像; 在所述二维图像的至少一些中沿所述关节成形术目标区域生成开环轮廓线; 并从开环轮廓线生成关节成形术目标区域的三维模型。

5. 发明申请

WO2010051122A1 ARTHROPLASTY SYSTEM AND RELATED METHODS 审中-公开
标题翻译：青光眼系统及相关方法
公开(公告)号：WO2010051122A1
公开(公告)日：2010-05-06
申请号：PCT/US2009/058946
申请日：2009-09-30
申请人： OTISMED CORPORATION , PARK, Ilwhan , CHI, Charlie W. , HOWELL, Stephen M.
发明人： PARK, Ilwhan , CHI, Charlie W. , HOWELL, Stephen M.
IPC分类号： A61B17/58
CPC分类号： A61B34/10 , A61B5/055 , A61B5/4504 , A61B5/4514 , A61B5/4533 , A61B5/4585 , A61B6/03 , A61B17/15 , A61B17/155 , A61B17/157 , A61B17/1703 , A61B17/1725 , A61B17/1739 , A61B17/1742 , A61B17/1764 , A61B2017/00526 , A61B2034/108 , B33Y80/00 , G06T7/0012 , G06T7/13 , G06T7/30 , G06T2207/30008
摘要： A method of manufacturing an arthroplasty jig is disclosed herein. The method may include the following: generate a bone model, wherein the bone model includes a three dimensional computer model of at least a portion of a joint surface of a bone of a patient joint to undergo an arthroplasty procedure; generate an implant model, wherein the implant model includes a three dimensional computer model of at least a portion of a joint surface of an arthroplasty implant to be used in the arthroplasty procedure; assess a characteristic associated with the patient joint; generate a modified joint surface of the implant model by modifying at least a portion of a joint surface of the implant model according to the characteristic; and shape match the modified joint surface of the implant model and a corresponding joint surface of the bone model.
摘要翻译：本文公开了一种制造关节成形术夹具的方法。该方法可以包括以下内容：产生骨模型，其中所述骨模型包括患者关节的骨的关节表面的至少一部分的三维计算机模型以进行关节成形术; 产生植入物模型，其中所述植入模型包括用于关节成形术过程的关节成形植入物的关节表面的至少一部分的三维计算机模型; 评估与患者关节相关的特征; 通过根据特征修改植入物模型的关节表面的至少一部分来生成植入物模型的修改的关节表面; 并且形状匹配植入物模型的修改的关节表面和骨模型的对应关节表面。

6. 发明申请

WO2010011590A1 SYSTEM AND METHOD FOR MANUFACTURING ARTHROPLASTY JIGS HAVING IMPROVED MATING ACCURACY 审中-公开
标题翻译：制造具有改进的准确度的牙根管的系统和方法
公开(公告)号：WO2010011590A1
公开(公告)日：2010-01-28
申请号：PCT/US2009/051109
申请日：2009-07-20
申请人： OTISMED CORPORATION , PARK, Ilwhan
发明人： PARK, Ilwhan
IPC分类号： A61F2/30
CPC分类号： A61B34/10 , A61B17/15 , A61B17/155 , A61B17/157 , A61B17/1675 , A61B17/1764 , A61B17/58 , A61B2034/108
摘要： Disclosed herein is a method of defining a mating surface in a first side of an arthroplasty jig. The mating surface is configured to matingly receive and contact a corresponding patient surface including at least one of a bone surface and a cartilage surface. The first side is oriented towards the patient surface when the mating surface matingly receives and contacts the patient surface. The method may include: a) identifying a contour line associated with the patient surface as represented in a medical image; b) evaluating via an algorithm the adequacy of the contour line for defining a portion of the mating surface associated with the contour line; c) modifying the contour line if the contour line is deemed inadequate; and d) employing the modified contour line to define the portion of the mating surface associated with the contour line.
摘要翻译：本文公开了一种在关节置换夹具的第一侧中限定配合表面的方法。配合表面构造成配合地接合并接触包括骨表面和软骨表面中的至少一个的相应的患者表面。当配合表面配合地接收并接触患者表面时，第一侧面向病人表面。该方法可以包括：a）识别与医学图像中所表示的患者表面相关联的轮廓线; b）通过算法评估用于定义与轮廓线相关联的配合表面的一部分的轮廓线的适当性; c）如果轮廓线被认为不足，则修改轮廓线; 以及d）使用改进的轮廓线来限定与轮廓线相关联的配合表面的部分。

7. 发明申请

WO2014145691A1 GENERATION OF A MATING SURFACE MODEL FOR PATIENT SPECIFIC CUTTING GUIDE BASED ON ANATOMICAL MODEL SEGMENTATION 审中-公开
标题翻译：基于分解模型分类的患者特异性切割指南的表面模型的生成
公开(公告)号：WO2014145691A1
公开(公告)日：2014-09-18
申请号：PCT/US2014/030496
申请日：2014-03-17
申请人： OTISMED CORPORATION
发明人： PAVLOVSKAIA, Elena I. , SHPUNGIN, Boris E. , MISHIN, Oleg , SOMINSKAYA, Olga
IPC分类号： A61B17/56 , A61B19/00 , A61F2/30
CPC分类号： A61B19/50 , A61B17/154 , A61B17/155 , A61B34/10 , A61B2017/568 , A61B2034/105 , A61B2034/108 , A61F2/38
摘要： Implementations described and claimed herein provide systems and methods for generating a smooth mating surface model defining a mating surface of a customized arthroplasty jig. In one implementation, sagittal slices of a volumetric image of a patient bone are segmented with segmentation splines. An anatomically accurate model of the patient bone is generated from the segmentation splines. The anatomically accurate model includes anatomically accurate segmentation splines. The anatomically accurate segmentation splines are transformed into mating surface contours. Any inadequate segments of the mating surface contours are modified to obtain modified mating surface contours. A mating surface model of the patient bone is generated based on the mating surface contours and the modified mating surface contours. Three-dimensional cross-sections of the mating surface model are smoothed to generate the smooth mating surface model.
摘要翻译：本文描述和要求保护的实施例提供了用于产生限定定制关节成形术夹具的配合表面的平滑配合表面模型的系统和方法。在一个实现中，患者骨的体积图像的矢状切片被分割花键。从分割样条生成解剖学上准确的患者骨骼模型。解剖学上精确的模型包括解剖精确的分割样条。解剖学上精确的分割样条变换成匹配表面轮廓。匹配表面轮廓的任何不适当的部分被修改以获得改进的配合表面轮廓。基于配合表面轮廓和修改的配合表面轮廓产生患者骨的配合表面模型。匹配表面模型的三维横截面被平滑以产生平滑的配合表面模型。

8. 发明申请

WO2011130421A1 PREOPERATIVELY PLANNING AN ARTHROPLASTY PROCEDURE AND GENERATING A CORRESPONDING PATIENT SPECIFIC ARTHROPLASTY RESECTION GUIDE 审中-公开
标题翻译：预先计划生殖细胞程序并产生相应的患者特异性ARTHROPLASTY RESECTION指南
公开(公告)号：WO2011130421A1
公开(公告)日：2011-10-20
申请号：PCT/US2011/032342
申请日：2011-04-13
申请人： OTISMED CORPORATION , PARK, Ilwhan , SONG, Keun , MISHIN, Oleg , SANTARELLA, Michael
发明人： PARK, Ilwhan , SONG, Keun , MISHIN, Oleg , SANTARELLA, Michael
IPC分类号： A61B17/56
CPC分类号： A61B5/055 , A61B5/4528 , A61B5/4851 , A61B6/03 , A61B17/15 , A61B17/155 , A61B17/157 , A61B17/1703 , A61B17/1725 , A61B17/1739 , A61B17/1742 , A61B17/1757 , A61B17/1764 , A61B2034/108 , B33Y50/00 , B33Y80/00
摘要： Methods of manufacturing a custom arthroplasty resection guide or jig are disclosed herein. For example, one method may include: generating MRI knee coil two dimensional images, wherein the knee coil images include a knee region of a patient; generating MRI body coil two dimensional images, wherein the body coil images include a hip region of the patient, the knee region of the patient and an ankle region of the patient; in the knee coil images, identifying first locations of knee landmarks; in the body coil images, identifying second locations of the knee landmarks; run a transformation with the first and second locations, causing the knee coil images and body coil images to generally correspond with each other with respect to location and orientation.
摘要翻译：本文公开了制造定制关节成形术切除引导件或夹具的方法。例如，一种方法可以包括：产生MRI膝盖线圈二维图像，其中膝盖线圈图像包括患者的膝盖区域; 产生MRI体线圈二维图像，其中身体线圈图像包括患者的臀部区域，患者的膝部区域和患者的踝部区域; 在膝盖线圈图像中，识别膝盖地标的第一个位置; 在身体线圈图像中，识别膝盖地标的第二位置; 运行与第一和第二位置的变换，使得膝盖线圈图像和身体线圈图像相对于位置和取向一般对应。

9. 发明申请

WO2010075081A1 UNICOMPARTMENTAL CUSTOMIZED ARTHROPLASTY CUTTING JIGS AND METHODS OF MAKING THE SAME 审中-公开
标题翻译：口腔定制牙根切割切口及其制造方法
公开(公告)号：WO2010075081A1
公开(公告)日：2010-07-01
申请号：PCT/US2009/068055
申请日：2009-12-15
申请人： OTISMED CORPORATION , PARK, Ilwhan , KOEHLE, Michael , DEVEZA, Lorenzo R.
发明人： PARK, Ilwhan , KOEHLE, Michael , DEVEZA, Lorenzo R.
IPC分类号： A61B17/58
CPC分类号： A61B17/1764 , A61B17/155 , A61B17/157 , A61B2034/105 , A61B2034/108 , A61F2/3836 , B33Y80/00
摘要： Unicompartmental femoral and tibial arthroplasty jigs are disclosed. Each jig includes a first side, a second side opposite the first side and a mating surface. The mating surface is in the first side of each jig. The femoral jig mating surface is configured to matingly receive/contact a generally planar area of an anterior side of a femoral shaft generally proximal a patellar facet boarder and generally distal an articularis genu. The first side is configured to be oriented towards the arthroplasty target region surface when the mating surface matingly receives/contacts the planar area. The tibial jig's mating surface is configured to matingly receive/contact a generally planar area of an anterior side of a tibial shaft distal the tibial plateau edge and generally proximal the tibial tuberosity. The first side is configured to be oriented towards the arthroplasty target region surface when the mating surface matingly receives/contacts the planar area.
摘要翻译：公开了单室股骨和胫骨关节置换夹具。每个夹具包括第一侧，与第一侧相对的第二侧和配合表面。配合表面位于每个夹具的第一侧。股骨夹具配合表面构造成配合地接合/接触股骨轴的前侧的大致平坦的区域，该区域通常靠近髌骨小平面边界并且通常位于关节突侧。第一侧构造成当配合表面配合地接收/接触平面区域时朝向关节成形术目标区域表面定向。胫骨夹具的配合表面构造成配合地接合/接触远离胫骨平台边缘的胫骨轴的前侧的大致平坦的区域，并且通常接近胫骨结节。第一侧构造成当配合表面配合地接收/接触平面区域时朝向关节成形术目标区域表面定向。

10. 发明申请

WO2009111216A1 TOTAL HIP REPLACEMENT SURGICAL GUIDE TOOL 审中-公开
标题翻译：全髋关节置换手术指南
公开(公告)号：WO2009111216A1
公开(公告)日：2009-09-11
申请号：PCT/US2009/034983
申请日：2009-02-24
申请人： OTISMED CORPORATION , PARK, Ilwhan , KOEHLE, Michael , DEVEZA, Lorenzo R.
发明人： PARK, Ilwhan , KOEHLE, Michael , DEVEZA, Lorenzo R.
IPC分类号： A61B17/15
CPC分类号： A61B34/10 , A61B17/175 , A61B2017/568 , A61B2034/102 , A61B2034/105 , A61B2034/107 , A61B2034/108 , A61F2/3603 , A61F2/3609 , A61F2002/30878 , A61F2002/505 , B33Y80/00 , G05B19/41885 , Y02P90/14 , Y02P90/20
摘要： Disclosed herein is a surgical guide tool for use in total hip replacement surgery. The surgical guide tool may include a customized mating region and a resection guide. The customized mating region and the resection guide are referenced to each other such that, when the customized mating region matingly engages a surface area of a proximal femur, the resection guide will be aligned to guide a resectioning of the proximal femur along a preoperatively planned resection plane.
摘要翻译：本文公开了一种用于全髋关节置换手术的手术引导工具。手术引导工具可以包括定制的配合区域和切除引导件。定制的配合区域和切除引导件彼此参考，使得当定制的配合区域匹配地接合股骨近端的表面区域时，切除引导件将对准以引导股骨近端的切除术沿着术前计划的切除平面。

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