专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2009014996A3 MEDICAL DEVICES AND METHODS FOR CUTTING AND SUTURING BIOLOGICAL TISSUE 审中-公开
公开(公告)号：WO2009014996A3
公开(公告)日：2009-01-29
申请号：PCT/US2008/070406
申请日：2008-07-18
申请人： ZIMMER ORTHOBIOLOGICS, INC. , ZAPOROJAN, Victor , YAO, Jian Q. , BRISTOL, Rodney , LIU, Hui , WANG, Hali , XIAN, Hai-Qing
发明人： ZAPOROJAN, Victor , YAO, Jian Q. , BRISTOL, Rodney , LIU, Hui , WANG, Hali , XIAN, Hai-Qing
IPC分类号： A61B17/04 , A61B17/32
摘要： Medical devices (100, 200, 400) for cutting and suturing biological tissue generally include a shaft (102) and first and second guide members (108, 110) each including a first portion (112, 114) coupled to the shaft (102) at a first location and a second portion (116, 118) coupled to the shaft (102) at a second location. The first portions (112, 114) are movable along the shaft (102) relative to the second portions (116, 118), and the first and second guide members (108, 110) define an arcuate profile and are configured to flex in response to such movement. When used to cut tissue, the medical device (100) may further include a blade (106) positioned between the first and second guide members (108, 110). When used to suture tissue, one or more suture guides (240) may be provided on the first guide member (108) for directing a suture needle through tissue proximate the first guide member (108). Methods of repairing and replacing a meniscus using the medical devices (100, 200, 400) are also provided.

2. 发明申请

WO2008147692A1 DIFFERENTIALLY PROCESSED TISSUE AND PROCESSING METHODS THEREOF 审中-公开
标题翻译：不同加工组织及其加工方法
公开(公告)号：WO2008147692A1
公开(公告)日：2008-12-04
申请号：PCT/US2008/063582
申请日：2008-05-14
申请人： ZIMMER ORTHOBIOLOGICS, INC. , YAO, Jian, Q. , XIAN, Hai-Qing , GAO, Jizong , BRISTOL, Rodney , ZAPOROJAN, Victor , WANG, Hali , LIU, Hul
发明人： YAO, Jian, Q. , XIAN, Hai-Qing , GAO, Jizong , BRISTOL, Rodney , ZAPOROJAN, Victor , WANG, Hali , LIU, Hul
IPC分类号： A61L27/14 , A61L31/10 , A61L27/36 , A61L27/38 , A61F2/00
CPC分类号： A61L27/3608 , A61L27/3604 , A61L27/3683
摘要： A method of preparing an implantable biological device having a first tissue part and a second tissue part includes exposing the first tissue part to a first preparation method and preventing exposure of the second biological tissue part to the first preparation method. Preventing exposure of the second biological tissue part to the first preparation method may be achieved using an embedding technique, a coating technique, a covering technique, or physical isolation. The method may further include exposing the second tissue part to a second preparation method and preventing exposure of the first biological tissue part to the second preparation method. An apparatus for preparing an implantable biologic device includes an enclosure having first and second chambers separated by a partition member wherein a substantial portion of the first tissue part is within the first chamber and a substantial portion of the second tissue part is within the second chamber.
摘要翻译：制备具有第一组织部分和第二组织部分的可植入生物装置的方法包括将第一组织部分暴露于第一制备方法并防止第二生物组织部分暴露于第一制备方法。可以使用嵌入技术，涂覆技术，覆盖技术或物理隔离来防止第二生物组织部分暴露于第一制备方法。该方法可以进一步包括将第二组织部分暴露于第二制备方法并防止第一生物组织部分暴露于第二制备方法。一种用于制备可植入生物装置的装置，包括具有由分隔构件分开的第一和第二腔室的外壳，其中所述第一组织部分的大部分位于所述第一腔室内，并且所述第二组织部分的大部分位于所述第二腔室内。

3. 发明申请

WO2008154149A2 TISSUE PROCESSING FOR NONIMMUNOGENIC IMPLANTS 审中-公开
标题翻译：非发育性植入物的组织加工
公开(公告)号：WO2008154149A2
公开(公告)日：2008-12-18
申请号：PCT/US2008/064653
申请日：2008-05-23
申请人： ZIMMER ORTHOBIOLOGICS, INC. , WANG, Hali , LIU, Hui , XIAN, Hai-Qing , YAO, Jian, Q. , ZAPOROJAN, Victor
发明人： WANG, Hali , LIU, Hui , XIAN, Hai-Qing , YAO, Jian, Q. , ZAPOROJAN, Victor
IPC分类号： A61L27/36
CPC分类号： A61L27/3654 , A61K35/32 , A61K35/34 , A61K35/44 , A61L27/3633 , A61L27/3687 , A61L2430/40
摘要： Methods for processing tissues to render them suitable for implantation, e.g., in an orthopedic site. Tissues are rendered substantially acellular and substantially nonimmunogenic by exposure to processes that result in cell lysis 12, increasing permeability of the extracellular matrix 14, degrading the debris from lysis 16, and removing the debris 18. Methods of forming tissue implants, kits for processing tissue implants, and methods of using tissue implants are also disclosed.
摘要翻译：用于处理组织以使其适合植入的方法，例如在矫形部位。组织通过暴露于导致细胞裂解12，增加细胞外基质14的渗透性，降解碎裂16和去除碎屑的过程而呈现基本上无细胞并且基本上是非免疫原性的。形成组织植入物的方法，用于处理组织的试剂盒植入物和使用组织植入物的方法也被公开。

4. 发明申请

WO2009158634A2 SCAFFOLD COATED AND/OR IMPREGNATED WITH AT LEAST ONE BIOACTIVE AGENT FOR TISSUE REPAIR AND OTHER MEDICAL APPLICATIONS 审中-公开
标题翻译：用于组织修复和其他医学应用的至少一种生物活性剂的SCAFFOLD涂层和/或
公开(公告)号：WO2009158634A2
公开(公告)日：2009-12-30
申请号：PCT/US2009/048885
申请日：2009-06-26
申请人： ZIMMER ORTHOBIOLOGICS, INC. , XIAN, Hai-Qing , YAO, Jian, Q. , WANG, Hali , DAHESHIA, Massoud , LIU, Hui
发明人： XIAN, Hai-Qing , YAO, Jian, Q. , WANG, Hali , DAHESHIA, Massoud , LIU, Hui
IPC分类号： A61L27/22 , A61L27/54
CPC分类号： A61L27/22 , A61L27/54 , A61L2300/252 , A61L2300/414 , A61L2300/426 , A61L2300/43 , A61L2300/64
摘要： A system and method for producing a scaffold coated and/or impregnated with at least one bioactive agent. This is accomplished by culturing at least one cell in the same medium as a scaffold, but without physical contact between the at least one cell and the scaffold. The system includes a container having a surface defining an interior compartment. A medium is disposed within the interior compartment. At least one cell is disposed within the medium, the at least one cell being capable of producing at least one bioactive agent. Further, a scaffold is disposed within the medium. The scaffold is physically separated from the at least one cell such that there is no contact between the scaffold and the at least one cell. Thus, as the at least one cell produces at least one bioactive agent, such as a growth factor, the at least one bioactive agent enters the medium, and contacts and coats and/or impregnates the scaffold. However, due to the physical separation of the scaffold and at least one cell, the at least one cell is prevented from contacting and coating and/or impregnating the scaffold. Thus, only the desired bioactive agent or agents coat and/or impregnate the scaffold.
摘要翻译：用于生产用至少一种生物活性剂包被和/或浸渍的支架的系统和方法。这是通过在与支架相同的培养基中培养至少一个细胞，但是在至少一个细胞和支架之间没有物理接触来实现的。该系统包括具有限定内部隔间的表面的容器。介质设置在内部隔室内。至少一个细胞设置在培养基内，所述至少一个细胞能够产生至少一种生物活性剂。此外，在培养基内设置支架。骨架与至少一个细胞物理分离，使得支架与至少一个细胞之间不存在接触。因此，由于至少一个细胞产生至少一种生物活性剂，例如生长因子，所述至少一种生物活性剂进入培养基，并接触并涂覆和/或浸渍支架。然而，由于支架和至少一个电池的物理分离，防止了至少一个电池接触和涂覆和/或浸渍支架。因此，只有所需的生物活性剂或试剂包衣和/或浸渍支架。

5. 发明申请

WO2009100065A2 METHOD OF REMOVING UNDESIRED TISSUE FROM CONNECTIVE TISSUE 审中-公开
标题翻译：从连接组织中去除不良组织的方法
公开(公告)号：WO2009100065A2
公开(公告)日：2009-08-13
申请号：PCT/US2009/032961
申请日：2009-02-03
申请人： ZIMMER ORTHOBIOLOGICS, INC. , XIAN, Hai-Qing , WANG, Hali , LIU, Hui , YAO, Jian, Q. , GAO, Jizong
发明人： XIAN, Hai-Qing , WANG, Hali , LIU, Hui , YAO, Jian, Q. , GAO, Jizong
IPC分类号： A61K38/48
CPC分类号： A61K38/4826 , A61K38/465 , C12Y301/01003 , C12Y304/21004
摘要： A method of removing undesired tissue from a connective tissue is provided that includes stretching the connective tissue and peeling away the undesired tissue. Some methods include soaking the connective tissue in a solution prior to and/or subsequent to stretching and peeling away the undesired tissue. The solution may include a detergent, an enzyme, a salt solution, an organic solvent, and combinations thereof.
摘要翻译：提供从结缔组织中去除不想要的组织的方法，其包括拉伸结缔组织并剥离不想要的组织。一些方法包括在拉伸和/或剥离不想要的组织之前和/或之后将结缔组织浸泡在溶液中。溶液可以包括洗涤剂，酶，盐溶液，有机溶剂及其组合。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式