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1. 发明申请

WO2010017954A2 OPTICAL COHERENCE REFLECTOMETRY WITH DEPTH RESOLUTION 审中-公开
标题翻译：低分辨率光学KOHÄRENZREFLEKTROMETRIE
公开(公告)号：WO2010017954A2
公开(公告)日：2010-02-18
申请号：PCT/EP2009005811
申请日：2009-08-11
申请人： ZEISS CARL MEDITEC AG , HACKER MARTIN , BARTH ROLAND , BERGNER ROLAND , BISSMANN WILFRIED , VON BUENAU RUDOLF , EBERSBACH RALF , KOSCHMIEDER INGO , FERCHER ADOLF FRIEDRICH , GRAJCIAR BRANISLAV
发明人： HACKER MARTIN , BARTH ROLAND , BERGNER ROLAND , BISSMANN WILFRIED , VON BUENAU RUDOLF , EBERSBACH RALF , KOSCHMIEDER INGO , FERCHER ADOLF FRIEDRICH , GRAJCIAR BRANISLAV
IPC分类号： A61B3/10
CPC分类号： A61B3/1005
摘要： A device for performing measurements on an eye (4), in particular for measuring the depth of the anterior chamber, the lens thickness, the corneal thickness or the axial length, wherein the device comprises an interferometer (10), focuses at least one measurement beam (7, 8) into the eye (4) along an optical axis (OA), records backscattered radiation and interferometrically generates a measurement signal displaying structures of the eye by time-domain, spectral-domain or Fourier-domain coherence reflectometry, has an adjustment apparatus (13; 16; 17; 19; 21) for laterally and/or axially displacing the focus in the eye (4) or for varying a polarization state of the measurement beam (7, 8) and has a control apparatus (22) which actuates the interferometer, wherein the control apparatus (22) generates a plurality of A-scan individual signals from the backscattered radiation, combines these to an A-scan measurement signal and is designed such that it actuates the adjustment apparatus (13; 16; 17; 19; 21) for displacing the position of the focus or for varying the polarization while recording the backscattered radiation from which the control apparatus (22) generates the A-scan individual signals is being recorded and backscattered radiation contributes to the A-scan measurement signal in a plurality of different positions of the focus or in a plurality of different polarization states of the measurement radiation (7, 8).
摘要翻译：装置，用于测量在眼睛上（4），特别是用于测量前房深度，透镜厚度，角膜厚度或轴向长度，所述装置包括在眼睛中的干涉仪（10），至少一个测量光束（7,8）沿光轴（OA）（4）聚焦接收反向散射的辐射，并且干涉由时域而产生，Spektraldomänen-或傅立叶域Kohärenzreflektrometrie指示测量的信号，调节装置的眼睛的结构，以便于聚焦的横向和/或轴向位移（13; 21 16; 17; 19）在眼（4），或用于改变测量光束的偏振状态（7,8）和控制装置（22）驱动所述的干涉仪，所述从所述背散射辐射控制装置（22）产生的多个扫描的各个信号的，并总结A扫描测量信号，并且适于将所述调节装置（13; 16; 17; 19; 21），用于移动所述位置的焦点的，或到偏振变化的后向散射辐射的记录，从该控制装置（22）在焦点处或测量辐射的多个不同偏振状态的几个不同的位置产生的A扫描的各个信号，驱动器和后向散射辐射期间（7,8），用于 A扫描测量信号有贡献。

2. 发明申请

WO2006105903A3 METHOD AND APPARATUS FOR MEASURING MOTION OF A SUBJECT USING A SERIES OF PARTIAL IMAGES FROM AN IMAGING SYSTEM 审中-公开
标题翻译：用于使用成像系统的一系列部分图像测量主体的运动的方法和装置
公开(公告)号：WO2006105903A3
公开(公告)日：2007-01-25
申请号：PCT/EP2006002883
申请日：2006-03-30
申请人： ZEISS CARL MEDITEC AG , EVERETT MATTHEW J , FLACHENECKER CLAUS , HACKER MARTIN , MEYER SCOTT A , O'HARA KEITH E , WILLIAMS RICK A
发明人： EVERETT MATTHEW J , FLACHENECKER CLAUS , HACKER MARTIN , MEYER SCOTT A , O'HARA KEITH E , WILLIAMS RICK A
IPC分类号： A61B3/12 , A61B3/113
CPC分类号： A61B3/102 , A61B3/113
摘要： A line scan imager is used to determine the motion of a subject. Each line of image data from the line scan imager is compared with a reference image. The location of a matching line in the reference image reveals the displacement of the subject. The current subject displacement can be determined based on each line of image data. The resulting displacement information can be used to correctly place other optical beams on the subject. The method can be applied to tracking the human eye to facilitate measurement, imaging, or treatment with a beam of optical radiation.
摘要翻译：行扫描成像器用于确定被摄体的运动。将来自行扫描成像器的每行图像数据与参考图像进行比较。参考图像中匹配线的位置显示了被摄体的位移。可以基于每行图像数据来确定当前被摄体位移。所得到的位移信息可用于将其他光束正确地放置在被摄体上。该方法可以应用于跟踪人眼以便于用光束照射进行测量，成像或处理。

3. 发明申请

WO2014049124A1 DEVICE FOR RELIABLY DETERMINING BIOMETRIC MEASUREMENT VARIABLES OF THE WHOLE EYE 审中-公开
标题翻译：用于可靠地确定整个眼睛的生物量测量变量的设备
公开(公告)号：WO2014049124A1
公开(公告)日：2014-04-03
申请号：PCT/EP2013070199
申请日：2013-09-27
申请人： ZEISS CARL MEDITEC AG
发明人： EBERSBACH RALF , HACKER MARTIN , ANTKOWIAK GERARD , KLOPFLEISCH PETER , BAJRAMOVIC FERID , BUEHREN TOBIAS , REICH MATTHIAS
IPC分类号： A61B3/107
CPC分类号： A61B3/107 , A61B3/1005 , A61B3/102 , A61B3/1173
摘要： Device for reliably determining biometric measurement variables of the whole eye The present invention relates to a device for determining biometric variables of the eye, as are incorporated in the calculation of intraocular lenses. The device according to the invention for measuring biometric variables of the eye consists of a multi- point keratometer and an OCT arrangement, solved by virtue of the fact that the multi-point keratometer is configured such that the keratometer measurement points are illuminated telecentrically and detected telecentrically and that the OCT arrangement is designed as a laterally scanning swept- source system with a detection region detecting the whole eye over the whole axial length thereof. The multi-point keratometer ensures that a sufficient number of keratometer points are available for measuring the corneal surface. By contrast, telecentricity ensures that the positioning inadequacies of the measuring instrument in relation to the eye to be measured do not lead to a local mismatch of the reflection points. What the swept-source OCT scan, which detects the whole eye over the length thereof, achieves is that both anterior chamber structures and retina structures can be detected and a consistent whole eye image can be realized
摘要翻译：用于可靠地确定整个眼睛的生物测定变量的装置技术领域本发明涉及一种用于确定眼睛的生物特征变量的装置，如同纳入眼内透镜的计算中的装置。根据本发明的用于测量眼睛生物特征变量的装置由多点角膜曲率计和OCT装置组成，其通过多点角膜曲率计的配置使得角膜曲率计测量点被远心地照射并检测并且OCT布置被设计为横扫扫描系统，其检测区域在其整个轴向长度上检测整个眼睛。多点角膜曲率计确保足够数量的角膜曲率计可用于测量角膜表面。相比之下，远心性确保测量仪器相对于被测眼睛的定位不足不会导致反射点局部不匹配。检测整个眼睛长度的扫描源OCT扫描实现的是，可以检测前房结构和视网膜结构，并且可以实现一致的全眼图像

4. 发明申请

WO2014140258A3 MULTIMODAL INTEGRATION OF OCULAR DATA ACQUISITION AND ANALYSIS 审中-公开
标题翻译：数据采集和分析的多模式整合
公开(公告)号：WO2014140258A3
公开(公告)日：2014-12-04
申请号：PCT/EP2014055078
申请日：2014-03-14
申请人： ZEISS CARL MEDITEC AG
发明人： DURBIN MARY , STETSON PAUL F , SHARMA UTKARSH , NARASIMHA-IYER HARIHAR , HACKER MARTIN , JONES ALLEN , RITTER CHRISTINE N , HAMILTON DONALD
IPC分类号： A61B3/10 , A61B3/18
CPC分类号： A61B5/4842 , A61B3/0025 , A61B3/102 , A61B3/18
摘要： Regions-of-interest discovered from analyses of images obtained from one imaging modality can be further observed, analyzed, supplemented, and further analyzed by one or more additional imaging modalities and in an automated way. In addition, one or more pathologies identified from analyses of these regions-of-interest, and a metric of the likelihood of the presence of disease, and/or a metric of risk of disease progression can be derived therefrom.
摘要翻译：通过从一种成像模式获得的图像分析发现的兴趣区域可以进一步观察，分析，补充，并通过一个或多个附加成像模式和自动化方式进一步分析。此外，可以从其中导出从这些感兴趣区域的分析中鉴定的一种或多种病理学，以及疾病存在的可能性的度量和/或疾病进展的风险度量。

5. 发明申请

WO2010060622A3 IMAGING SYSTEM 审中-公开
标题翻译：成像系统
公开(公告)号：WO2010060622A3
公开(公告)日：2010-07-29
申请号：PCT/EP2009008433
申请日：2009-11-26
申请人： ZEISS CARL SURGICAL GMBH , HAUGER CHRISTOPH , SEESSELBERG MARKUS , HACKER MARTIN , O'HARA KEITH
发明人： HAUGER CHRISTOPH , SEESSELBERG MARKUS , HACKER MARTIN , O'HARA KEITH
IPC分类号： G01B9/02 , A61B3/10 , A61B3/13
CPC分类号： A61B3/102 , A61B3/005 , A61B3/117 , A61B3/12 , A61B3/1225 , A61B3/13 , A61B3/14 , G01B9/02004 , G01B9/0203 , G01B9/02035 , G01B9/02044 , G01B9/02091 , G02B7/14 , G02B27/0955
摘要： Imaging systems are provided allowing examination of different object regions spaced apart in a depth direction by visual microscopy and by optical coherence tomography. An axial field of view and a lateral resolution is varied depending on which object region is examined by the imaging system. The proposed imaging systems are in particular applicable for thorough examination of the human eye.
摘要翻译：提供成像系统，允许通过视觉显微镜和光学相干断层扫描检查在深度方向上间隔开的不同物体区域。轴向视场和横向分辨率根据成像系统检查哪个物体区域而变化。所提出的成像系统特别适用于彻底检查人眼。

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