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1. 发明申请

WO2004011457A1 1-PHENYLPIPERIDIN-3-ONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF 审中-公开
标题翻译： 1-苯基哌啶-3-酮衍生物及其制备方法
公开(公告)号：WO2004011457A1
公开(公告)日：2004-02-05
申请号：PCT/KR2003/001502
申请日：2003-07-26
申请人： YUHAN CORPORATION , DONG-A PHARMACEUTICAL CO., LTD. , LEE, Jong-Wook , LEE, Bong-Yong , LEE, Chun-Ho , HUR, Yun , HAN, Tae-Dong , KO, Hyun-Kyoung , YUN, Suk-Won , SHIM, Jae-Young , LIM, Joong-In , SON, Moon-Ho , YANG, Jae-Sung , KIM, Mi-Kyung
发明人： LEE, Jong-Wook , LEE, Bong-Yong , LEE, Chun-Ho , HUR, Yun , HAN, Tae-Dong , KO, Hyun-Kyoung , YUN, Suk-Won , SHIM, Jae-Young , LIM, Joong-In , SON, Moon-Ho , YANG, Jae-Sung , KIM, Mi-Kyung
IPC分类号： C07D405/12
CPC分类号： C07D401/12 , C07D211/62 , C07D211/74 , C07D401/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/14 , C07D417/14
摘要： The present invention provides 1-phenylpiperidin-3-one derivatives and pharmaceutically acceptable saltsthereof, having cysteine protease inhibitory activity, pharmaceutical compositions containing the sameas an active ingredient, and processes for the preparation thereof.
摘要翻译：本发明提供具有半胱氨酸蛋白酶抑制活性的1-苯基哌啶-3-酮衍生物和药学上可接受的盐，其含有活性成分的药物组合物及其制备方法。

2. 发明申请

WO2008108602A1 NOVEL PHENYLPROPIONIC ACID DERIVATIVES AS PEROXISOME PROLIFERATOR-ACTIVATED GAMMA RECEPTOR MODULATORS, METHOD OF THE SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME 审中-公开
标题翻译：新戊二酸衍生物作为过氧化物促进剂活化的游离体受体调节剂，其方法和包含其的药物组合物
公开(公告)号：WO2008108602A1
公开(公告)日：2008-09-12
申请号：PCT/KR2008/001322
申请日：2008-03-07
申请人： DONG-A PHARM. CO., LTD. , YUHAN CO., LTD. , MOON, Ho-Sang , YOO, Moo-Hi , KIM, Soon-Hoe , LIM, Joong-In , SON, Moon-Ho , KIM, Mi-Kyung , SHIN, Chang-Yell , KIM, Jin-Kwan , PARK, Sang-Kuk , CHAE, Yu-Na , SHIM, Hyun-Joo , JEON, Sun-Ho , KIM, Hae-Sun , WIE, Gil-Tae , KIM, Dong-Hwan , LEE, Byung-Kyu , PARK, Chan-Sun , AHN, Byung-Nak , KIM, Eunkyung , BAE, Myung-Ho , SHIN, Young-Ah , HUR, Youn , LEE, Chun-Ho , CHOI, Hyun-Ho , KIM, Bongtae , CHONG, Wonee
发明人： MOON, Ho-Sang , YOO, Moo-Hi , KIM, Soon-Hoe , LIM, Joong-In , SON, Moon-Ho , KIM, Mi-Kyung , SHIN, Chang-Yell , KIM, Jin-Kwan , PARK, Sang-Kuk , CHAE, Yu-Na , SHIM, Hyun-Joo , JEON, Sun-Ho , KIM, Hae-Sun , WIE, Gil-Tae , KIM, Dong-Hwan , LEE, Byung-Kyu , PARK, Chan-Sun , AHN, Byung-Nak , KIM, Eunkyung , BAE, Myung-Ho , SHIN, Young-Ah , HUR, Youn , LEE, Chun-Ho , CHOI, Hyun-Ho , KIM, Bongtae , CHONG, Wonee
IPC分类号： C07D333/16
CPC分类号： C07D333/16 , C07D409/10 , C07D409/12 , C07D413/10 , C07D417/10
摘要： The present invention provides a novel phenylpropionic acid derivative and a PPAR-γ modulator comprising the same as an active ingredient. The phenylpropionic acid derivative of the present invention has modulatory action on function of PPAR-γ and then exhibits hypoglycemic, hypolipidemic and insulin resistance-reducing effects on PPAR-mediated diseases or disorders. Therefore, the present invention is prophylactically or therapeutically effective for diabetes and metabolic diseases.
摘要翻译：本发明提供新的苯丙酸衍生物和PPAR- 包含其作为活性成分的调节剂。本发明的苯丙酸衍生物对PPAR-α的功能具有调节作用然后对PPAR介导的疾病或病症表现出降血糖，降血脂和胰岛素抵抗减少作用。因此，本发明对于糖尿病和代谢疾病具有预防性或治疗上的有效性。

3. 发明申请

WO2011122815A2 NOVEL QUINOXALINE DERIVATIVES 审中-公开
标题翻译：新型喹啉衍生物
公开(公告)号：WO2011122815A2
公开(公告)日：2011-10-06
申请号：PCT/KR2011/002115
申请日：2011-03-28
申请人： DONG-A PHARM.CO.,LTD. , MOON, Ho-Sang , YANG, Jae-Sung , KIM, Mi-Kyung , KIM, Jin-Kwan , LEE, Jae-Young , KANG, So-Mi , KIM, Ha-Dong , SHIN, Chang-Yell , CHEONG, Ye-Hwang , YANG, Eun-Kyoung , CHOI, Song-Hyen , PARK, Young-Soo , KIM, Eun-Jung , CHAE, Yu-Na , CHO, Eun-Jung , SON, Moon-Ho , KIM, Soon-Hoe
发明人： MOON, Ho-Sang , YANG, Jae-Sung , KIM, Mi-Kyung , KIM, Jin-Kwan , LEE, Jae-Young , KANG, So-Mi , KIM, Ha-Dong , SHIN, Chang-Yell , CHEONG, Ye-Hwang , YANG, Eun-Kyoung , CHOI, Song-Hyen , PARK, Young-Soo , KIM, Eun-Jung , CHAE, Yu-Na , CHO, Eun-Jung , SON, Moon-Ho , KIM, Soon-Hoe
IPC分类号： C07D417/14 , C07D403/12 , A61K31/498 , A61P3/10 , A61P3/04
CPC分类号： C07D417/14 , C07D403/12
摘要： This invention relates to a novel compound represented by the following Chemical Formula 1, a process for preparing it, and its pharmaceutically approved salt comprising it as an active ingredient. The compound of this invention is GLP 1 receptor regulating low molecular weight compound useful for treatment of metabolic diseases such as diabetes and obesity by regulating the function of glucagon like peptide 1 receptor (GLP 1 receptor) for the disease or disorder carried by GLP 1 since it has the effects on a drop of blood sugar and an improvement of insulin resistance.
摘要翻译：本发明涉及由以下化学式1表示的新化合物，其制备方法及其药学上可接受的盐，其包含作为活性成分的盐。本发明的化合物是通过调节GLP1携带的疾病或病症的胰高血糖素样肽1受体（GLP 1受体）的功能，可用于治疗糖尿病和肥胖等代谢疾病的GLP 1受体调节低分子化合物，因为它对一滴血糖和胰岛素抵抗的改善具有影响。

4. 发明申请

WO2008130151A1 DPP-IV INHIBITOR INCLUDING BETA-AMINO GROUP, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME FOR PREVENTING AND TREATING A DIABETES OR AN OBESITY 审中-公开
标题翻译：包含β-氨基的DPP-IV抑制剂及其制备方法和含有该组合物的药物组合物用于预防和治疗糖尿病或肥胖
公开(公告)号：WO2008130151A1
公开(公告)日：2008-10-30
申请号：PCT/KR2008/002203
申请日：2008-04-18
申请人： DONG-A PHARM. CO., LTD. , KIM, Heung Jae , KWAK, Woo Young , SHIN, Chang Yell , KIM, Hadong , MIN, Jong Pil , PARK, Kyung Jin , LEE, Jae Young , CHOI, Song-Hyen , YOON, Tae Hyun , KIM, Hae-Sun , JANG, Ji Myun , KIM, Mi-Kyung , SON, Moon-Ho , KIM, Soon Hoe , YOO, Moohi
发明人： KIM, Heung Jae , KWAK, Woo Young , SHIN, Chang Yell , KIM, Hadong , MIN, Jong Pil , PARK, Kyung Jin , LEE, Jae Young , CHOI, Song-Hyen , YOON, Tae Hyun , KIM, Hae-Sun , JANG, Ji Myun , KIM, Mi-Kyung , SON, Moon-Ho , KIM, Soon Hoe , YOO, Moohi
IPC分类号： C07D241/08 , A61K31/4704 , A61P3/10
CPC分类号： C07D241/08
摘要： The present invention provides a novel heterocyclic compound containing a beta-amino group, a method for preparing the same, and a pharmaceutical composition comprising the same heterocyclic compound or a pharmaceutically acceptable salt thereof as an active ingredient. The heterocyclic compound of the present invention exhibits excellent DPP-IV inhibitory activity and bioavailability and therefore can be useful for the prophylaxis or treatment of DPP-IV-related diseases such as diabetes or obesity.
摘要翻译：本发明提供了一种新的含有β-氨基的杂环化合物，其制备方法以及含有相同的杂环化合物或其药学上可接受的盐作为活性成分的药物组合物。本发明的杂环化合物表现出优异的DPP-IV抑制活性和生物利用度，因此可用于预防或治疗DPP-IV相关疾病，例如糖尿病或肥胖症。

5. 发明申请

WO2011118976A2 PHARMACEUTICAL COMPOSITION FOR THE PREVENTION OR THE TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE AND THE METHOD FOR PREVENTION OR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE USING THE SAME 审中-公开
标题翻译：用于预防或治疗非酒精性脂肪肝疾病的药物组合物及使用该方法预防或治疗非酒精性脂肪肝病
公开(公告)号：WO2011118976A2
公开(公告)日：2011-09-29
申请号：PCT/KR2011/001988
申请日：2011-03-23
申请人： DONG-A PHARM. CO., LTD. , AN, Gook-Jun , YANG, Eun-Kyoung , CHO, Eun-Jung , CHAE, Yu-Na , CHOI, Song-Hyen , KIM, Ha-Dong , SHIN, Chang-Yell , KIM, Mi-Kyung , KWAK, Woo-Young , KIM, Heung-Jae , SON, Moon-Ho , KIM, Soon-Hoe
发明人： AN, Gook-Jun , YANG, Eun-Kyoung , CHO, Eun-Jung , CHAE, Yu-Na , CHOI, Song-Hyen , KIM, Ha-Dong , SHIN, Chang-Yell , KIM, Mi-Kyung , KWAK, Woo-Young , KIM, Heung-Jae , SON, Moon-Ho , KIM, Soon-Hoe
IPC分类号： A61K31/496 , A61K31/401 , A61P1/16 , A61P1/00
CPC分类号： A61K31/495 , A61K31/4985
摘要： The present invention provides a pharmaceutical composition for the prevention and treatment of a non-alcoholic fatty liver disease (NAFLD), containing an active ingredient selected from the group consisting of Compound 1 represented by formula 1, sitagliptin, vildagliptin, linagliptin or a pharmaceutically acceptable salt thereof. Further, the present invention provides a method for the prevention or treatment of a non-alcoholic fatty liver disease, including administering an effective amount of an active ingredient selected from the group consisting of Compound 1 represented by formula 1, sitagliptin, vildagliptin, linagliptin or a pharmaceutically acceptable salt thereof to a mammal including a human in need thereof. Further, the present invention provides use of Compound 1 represented by formula 1, sitagliptin, vildagliptin, linagliptin or a pharmaceutically acceptable salt thereof, for manufacturing a pharmaceutical composition for the prevention or treatment of a non-alcoholic fatty liver disease.
摘要翻译：本发明提供了一种用于预防和治疗非酒精性脂肪肝疾病（NAFLD）的药物组合物，其含有选自由式1表示的化合物1，西格列汀，维格列汀，利格列汀或其药学上可接受的组的盐。此外，本发明提供了一种预防或治疗非酒精性脂肪性肝病的方法，包括给予有效量的选自由式1表示的化合物1，西格列汀，维格列汀，利格列汀或其药学上可接受的盐包括需要其的人的哺乳动物。此外，本发明提供了用于制备用于预防或治疗非酒精性脂肪肝疾病的药物组合物的式1化合物1，西他列汀，维格列汀，利格列汀或其药学上可接受的盐的用途。

6. 发明申请

WO2007142404A1 CAMERA DEVICE WITH VACUUM TUBE 审中-公开
标题翻译：具有真空管的摄像机
公开(公告)号：WO2007142404A1
公开(公告)日：2007-12-13
申请号：PCT/KR2007/001834
申请日：2007-04-16
申请人： YEOM, Dong-Yeop , KIM, Mi-Kyung
发明人： YEOM, Dong-Yeop , KIM, Mi-Kyung
IPC分类号： G03B17/08
CPC分类号： G03B17/08 , G08B13/19619
摘要： The present invention relates to a camera device with a vacuum tube; and, more particularly, to a camera device using a vacuum tube capable of being used for a fixed outdoor surveillance camera and a camera module supported by a supporting member inside of the vacuum tube. The camera device includes a vacuum tube, a camera module installed inside of the vacuum tube, a supporting member for supporting the camera module on the vacuum tube, a pin installed at a lower part of the vacuum tube, which is connected with a socket for electrically connecting
摘要翻译：本发明涉及具有真空管的相机装置; 更具体地，涉及一种使用能够用于固定室外监视摄像机的真空管和由真空管内的支撑构件支撑的照相机模块的照相机装置。相机装置包括真空管，安装在真空管内部的相机模块，用于将相机模块支撑在真空管上的支撑部件，安装在真空管下部的销，其与插座连接，电连接

7. 发明申请

WO2008023966A1 NOVEL USE OF PANDURATIN A OR DERIVATIVES THEREOF 审中-公开
标题翻译：潘德拉汀A或其衍生物的新用途
公开(公告)号：WO2008023966A1
公开(公告)日：2008-02-28
申请号：PCT/KR2007/004109
申请日：2007-08-27
申请人： Industry-Academic Cooperation Foundation, Yonsei University , HWANG, Jae-Kwan , KIM, Mi-Kyung , SONG, Min-Soo , SHIM, Jae-Seok , YOON, Ji-Hoon
发明人： HWANG, Jae-Kwan , KIM, Mi-Kyung , SONG, Min-Soo , SHIM, Jae-Seok , YOON, Ji-Hoon
IPC分类号： A61K31/122
CPC分类号： A61K31/122
摘要： The present invention relates to the novel use of a panduratin A compound, derivative thereof or an extract of Kaempferia pandurata. More particularly, it relates to the use for the antibacterial activities and acne treatment of a panduratin A compound represented by Formula 1, a panduratin A derivative represented by Formula 2 or an extract of Kaempferia pandurata. The above panduratin A compound, derivative thereof or extract of Kaempferia pandurata has excellent antibacterial activity of inhibiting the growth of bacteria selected from the group consisting of Propionibacterium acnes, Staphylococcus epidermidis, Micrococcus luteus, Staphylococcus aureus, Staphylococcus warneri, Staphylococcus haemolyticus, Staphylococcus xylosus, Staphylococcus hominis and Staphylococcus saprophyticus. Accordingly, the inventive compounds or extract may be very useful as an antibacterial composition or a composition for treating acne against the above bacteria.
摘要翻译：本发明涉及一种潘多蛋白A化合物，其衍生物或山茶皮提取物的新用途。更具体地说，涉及用式1表示的潘多蛋白A化合物，式2表示的潘多汀A衍生物或白头翁提取物的抗菌活性和痤疮治疗用途。上述潘多蛋白A化合物，其衍生物或山茶皮提取物具有优异的抗菌活性，其抑制选自以下的细菌的生长：丙酸杆菌属，表皮葡萄球菌，藤黄微球菌，金黄色葡萄球菌，葡萄球菌，溶血葡萄球菌，葡萄球菌，人类葡萄球菌和腐生葡萄球菌。因此，本发明化合物或提取物可以作为抗菌组合物或用于治疗针对上述细菌的痤疮的组合物非常有用。

8. 发明申请

WO2007123313A1 BIOCHIP AND METHOD FOR MANUFACTURING THE SAME 审中-公开
标题翻译：生物技术及其制造方法
公开(公告)号：WO2007123313A1
公开(公告)日：2007-11-01
申请号：PCT/KR2007/001727
申请日：2007-04-10
申请人： ADVANCED NANO PRODUCTS CO., LTD. , KIM, Mi-Kyung , PARK, Dong-Kyu , KIM, Ju-Young , PARK, Chang-Woo
发明人： KIM, Mi-Kyung , PARK, Dong-Kyu , KIM, Ju-Young , PARK, Chang-Woo
IPC分类号： G01N33/53
CPC分类号： B01J19/0046 , B01J2219/00378 , B01J2219/00527 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/00626 , B01J2219/00637 , B01J2219/00639 , B01J2219/00641 , B01J2219/00648 , B01J2219/00659 , B01J2219/00677 , B82Y30/00
摘要： Disclosed are a biochip and a method for manufacturing the same. The biochip comprises a substrate; a thin metal pattern formed on the substrate by patterning a metal solution with an inkjet printer; and a biomaterial immobilized on the thin metal pattern via a linker. The biochip, in which a thin metal pattern is freely formed through an inkjet printer, allows biomaterials to be formed in various patterns. The thin metal pattern, which can be easily formed in an inkjet printing ejection manner, can be produced in a mass scale. Also, the apparatus for manufacturing the biochip of the present invention is small and inexpensive. Further, thin metal pattern can be formed to a size as small as micrometers so that biomaterials can be integrated at high density. In addition, the method is environmentally friendly because there is no need to carry out a washing process for an etching process. No limitations are imposed on the kinds of the metal that can be used in the present invention, and silver can be used, which results in an improvement in the adhesiveness of the substrate to the thin metal pattern as well as in the immobilization efficiency of biomolecules.
摘要翻译：公开了一种生物芯片及其制造方法。生物芯片包括基底; 通过用喷墨打印机图案化金属溶液而形成在基板上的薄金属图案; 以及通过接头固定在薄金属图案上的生物材料。通过喷墨打印机自由形成薄金属图案的生物芯片允许以各种图案形成生物材料。可以以喷墨印刷喷射方式容易地形成的细金属图案可以以大规模生产。另外，本发明的生物芯片的制造装置小型化且价廉。此外，薄金属图案可以形成为小至微米的尺寸，使得生物材料可以以高密度积分。此外，该方法是环境友好的，因为不需要执行用于蚀刻工艺的洗涤工艺。对本发明中可以使用的金属种类没有限制，可以使用银，这导致基材与薄金属图案的粘附性以及生物分子的固定效率的改善。

9. 发明申请

WO2006049377A1 BRIDGE SLAB CONSTRUCTION METHOD AND LATTICE BAR DECK-SHAPED PRECAST CONCRETE PLATE APPLIED THERETO 审中-公开
标题翻译：桥梁施工方法和板条形成型预制混凝土板应用于
公开(公告)号：WO2006049377A1
公开(公告)日：2006-05-11
申请号：PCT/KR2005/001374
申请日：2005-05-11
申请人： HYOSUNG LB-DECK CO., LTD , KIM, Mi-Kyung
发明人： KIM, Mi-Kyung
IPC分类号： E01D19/10
CPC分类号： E01D19/125 , E01D2101/26
摘要： Provided is a method of constructing a slab of a bridge in which a plurality of girders are placed parallel to one another on upper surfaces of neighboring piers, a plurality of cross beams are formed between the girders, a plurality of lattice bar deck-shaped precast concrete plates that are separately precast are hoisted and installed by a deck truck, and concrete is placed after a plurality of reinforcing bars are arranged in an upper portion of the precast concrete plate, to cure a composite slab formed integrally with the precast concrete plate. In a precasting process of the lattice bar deck- shaped precast concrete plate, a plurality of reinforcing bars are arranged in a rectangular frame to be orthogonal in a lengthwise direction and a widthwise direction, a plurality of truss frames are arranged to protrude from the rectangular frame at both symmetrical positions with respect to a center of a lengthwise direction, and concrete is placed and cured in the rectangular frame so that the precast concrete plate maintains a high strength over a compression strength of the slab.
摘要翻译：提供了一种构造桥梁的方法，其中多个桁架彼此平行地放置在相邻墩的上表面上，在桁架之间形成多个横梁，多个网格甲板形预制件单独预制的混凝土板由甲板车提升和安装，并且在预制混凝土板的上部布置多个钢筋之后放置混凝土，以固化与预制混凝土板一体形成的复合板。在格栅甲板形预制混凝土板的预制工艺中，多个钢筋被布置成矩形框架，以沿长度方向和宽度方向正交，多个桁架框架被布置成从矩形框架在相对于长度方向的中心的两个对称位置处，并且将混凝土放置并固化在矩形框架中，使得预制混凝土板在板坯的压缩强度上保持高强度。

10. 发明申请

WO2004110525A1 AN OBSERVATION SYSTEM OF GIVING AN INJECTION OF RINGER'S SOLUTION 审中-公开
标题翻译：提供注射器的解决方案的观察系统
公开(公告)号：WO2004110525A1
公开(公告)日：2004-12-23
申请号：PCT/KR2004/001402
申请日：2004-06-11
申请人： KIM, Mi-Kyung
发明人： KIM, Mi-Kyung
IPC分类号： A61M5/14
CPC分类号： A61M5/16845 , A61M5/16881 , A61M39/28 , A61M2205/18 , A61M2205/3553
摘要： Disclosed herein is a system for monitoring the injection of Ringer’s solution. The monitoring system of the present invention includes a status detection device for measuring the weight of Ringer’s solution, converting the weight information of the Ringer’s solution into a data signal, and transmitting the data signal. A first line interface device receives the data signal from the status detection device, performs data conversion with respect to the data signal to allow identifier information required to identify the status detection device to be included in the data signal, and outputs the converted data to the communication line. A second line interface device receives the data signal through the communication line, and outputs the data signal to a remote monitoring device. The remote monitoring device decodes the data signal and outputs weight data of the Ringer’s solution according to the identifier information.
摘要翻译：本文公开了一种用于监测林格氏溶液注射的系统。本发明的监视系统包括用于测量林格氏解的权重的状态检测装置，将林格氏解的权重信息转换为数据信号，并发送数据信号。第一线路接口装置从状态检测装置接收数据信号，对数据信号执行数据转换，以允许识别要包括在数据信号中的状态检测装置所需的标识符信息，并将转换的数据输出到通讯线。第二线路接口装置通过通信线接收数据信号，并将数据信号输出到远程监视装置。远程监控设备对数据信号进行解码，并根据标识信息输出林格解决方案的权重数据。

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