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1. 发明申请

WO2013028968A1 3-DIMENSIONAL CARDIAC FIBROBLAST DERIVED EXTRACELLULAR MATRIX 审中-公开
标题翻译： 3维CARDIAC FIBROBLAST衍生细胞外基质
公开(公告)号：WO2013028968A1
公开(公告)日：2013-02-28
申请号：PCT/US2012/052252
申请日：2012-08-24
申请人： WISCONSIN ALUMNI RESEARCH FOUNDATION , SCHMUCK, Eric , SAUPE, Kurt
发明人： SCHMUCK, Eric , SAUPE, Kurt
IPC分类号： A61K35/28 , A61K35/54 , A61L15/32 , A61L15/40 , A61P9/00
CPC分类号： A61L27/3633 , A61K35/28 , A61K35/33 , A61K35/34 , A61K38/00 , A61L27/3687 , A61L27/3834 , A61L27/54 , A61L2300/414 , A61L2430/20 , C12N5/0657 , C12N5/0663 , C12N2513/00 , C12N2533/90 , A61K2300/00
摘要： A bioscaffold made from an isolated cardiac fibroblast-derived 3-dimensional extracellular matrix (ECM) is disclosed. The bioscaffold can be used as an epicardial patch for die delivery of therapeutic cells into myocardial tissue. Methods of making the 3-dimensional extracellular matrix using cultured cardiac fibroblasts are also disclosed.
摘要翻译：公开了由分离的心脏成纤维细胞衍生的3维细胞外基质（ECM）制成的生物支架。生物支架可用作心外膜贴片，用于将治疗细胞递送至心肌组织。还公开了使用培养的心脏成纤维细胞制备3维细胞外基质的方法。

2. 发明申请

WO2023039371A1 CARDIAC FIBROBLAST DERIVED EXTRACELLULAR MATRIX 审中-公开
公开(公告)号：WO2023039371A1
公开(公告)日：2023-03-16
申请号：PCT/US2022/075975
申请日：2022-09-06
申请人： WISCONSIN ALUMNI RESEARCH FOUNDATION
发明人： SCHMUCK, Eric , RAVAL, Amish , ROY, Sushmita , ZHOU, Tianhua
IPC分类号： A61L27/36 , C12N5/00 , C12N5/077 , A61K35/34 , A61L27/38
摘要： The disclosure generally relates to methods, cells, and compositions for preparing cardiac extracellular matrix. In particular, provided herein are methods tor preparing a cardiac extracellular matrix using SUSD2 High fibroblasts and SUSD2 High myofibroblasts.

3. 发明申请

WO2012082549A3 ILLUMINATION DEVICE 审中-公开
公开(公告)号：WO2012082549A3
公开(公告)日：2012-06-21
申请号：PCT/US2011/064145
申请日：2011-12-09
申请人： 3M INNOVATIVE PROPERTIES COMPANY , SCHMUCK, Eric , VOLLMERS, Hans-Gerd , BOSLER, Manfred , REMHOF, Tilo
发明人： SCHMUCK, Eric , VOLLMERS, Hans-Gerd , BOSLER, Manfred , REMHOF, Tilo
IPC分类号： F21V8/00 , G02B6/00
摘要： The present invention provides in one aspect a light device having a light guide. The light guide (20) has at least one major side defining a light extraction side (26). The light device further has at least one fibrous layer (30), typically a non-woven or woven fibrous layer, disposed on the major side of said light guide defining said light extraction side. At the light extraction side, the light device has a plurality of discrete bonding areas (40) at which the at least one fibrous layer is bonded to the major side of said light guide. In a particular aspect, the bonding areas define light extraction elements on the light extraction side. Such an arrangement typically provides for an easy, reliable and cost-effective light device useful for a variety of applications including, for example, illuminating the interior of a vehicle

4. 发明申请

WO2011035081A1 CONNECTOR 审中-公开
标题翻译：连接器
公开(公告)号：WO2011035081A1
公开(公告)日：2011-03-24
申请号：PCT/US2010/049205
申请日：2010-09-17
申请人： 3M INNOVATIVE PROPERTIES COMPANY , PURFUERST, Joerg Roberto , SCHUMANN, Norbert , KELLER, Thomas , SCHWARZ, Werner , RUDEK, David M. , SCHMUCK, Eric
发明人： PURFUERST, Joerg Roberto , SCHUMANN, Norbert , KELLER, Thomas , SCHWARZ, Werner , RUDEK, David M. , SCHMUCK, Eric
IPC分类号： F21V8/00
CPC分类号： G02B6/0006 , G02B6/001
摘要： A connector adapted for use in an illumination system comprising at least one optical element, such as an optical fibre. is disclosed. The connector comprises a housing dimensioned so that internally it retains at least one end portion of at least one optical element, and externally substantially follows the shape of the end portion(s) of the optical element(s). This forms a join between the ends of the optical element(s). A light source is also contained within the housing and positioned so as to illuminate the end portions of at least one optical element. Electrical connection means adapted to connect the light source to an external power supply are provided. The electrical connection means being moveable relative to the housing. The electrical connection means may be carried by a flexible substrate, or may be formed by slideable contacts within a light guide rail.
摘要翻译：适用于包括至少一个光学元件（例如光纤）的照明系统中的连接器。被披露。连接器包括尺寸为使得其内部保持至少一个光学元件的至少一个端部并且外部基本上遵循光学元件的端部部分的形状的壳体。这形成了光学元件的端部之间的连接。光源还包含在壳体内并且被定位成照亮至少一个光学元件的端部。提供了适于将光源连接到外部电源的电连接装置。电连接装置可相对于外壳移动。电连接装置可以由柔性基板承载，或者可以由光导轨内的可滑动触点形成。

5. 发明申请

WO2011056811A1 SIDE LIGHT GUIDE AND LIGHT DEVICE 审中-公开
标题翻译：侧灯指示灯和灯光装置
公开(公告)号：WO2011056811A1
公开(公告)日：2011-05-12
申请号：PCT/US2010/055198
申请日：2010-11-03
申请人： 3M INNOVATIVE PROPERTIES COMPANY , RUDEK, David M. , VOGT, Hans-Michael , HEINZ, Robert , LINGK, Oliver , SCHMUCK, Eric
发明人： RUDEK, David M. , VOGT, Hans-Michael , HEINZ, Robert , LINGK, Oliver , SCHMUCK, Eric
IPC分类号： G02B6/00
CPC分类号： G02B6/0001 , B60Q1/302 , B60Q3/64 , F21S43/14 , F21S43/237 , F21S43/245 , F21S43/249 , F21S43/27 , G02B6/001 , G02B6/0088
摘要： The present invention provides in one aspect a side-light guide (10) having a naked core (20) of transparent polymeric material without a cladding. The side-light guide has a first surface (30) defining a light emitting surface extending longitudinally along the side-light guide and a second surface (24) having light- extraction elements (32) extending longitudinally along the side-light guide and the second surface is arranged generally opposite to the first surface, the side-light guide has a generally circular cross - section comprising cut away regions (40) at opposing sides defining on each opposite side at least one planar surface (44) tapering inwardly from the first towards the second surface. Further provided is a light device (100) comprising the side-light guide.
摘要翻译：本发明在一个方面提供了一种具有透明聚合材料的裸芯（20）而没有包层的侧光导向件（10）。所述侧光引导件具有限定沿着所述侧光导向件纵向延伸的发光表面的第一表面（30）和具有沿着所述侧光导向件纵向延伸的光提取元件（32）的第二表面（24）第二表面大体上与第一表面相对地设置，侧光导件具有大致圆形的横截面，该横截面包括相对侧的切除区域（40），每个相对侧在每个相对侧上限定至少一个平坦表面（44），该平坦表面从首先朝向第二面。还提供了一种包括该侧光导管的光装置（100）。

6. 发明申请

WO2011035116A1 MOUNTING MAT 审中-公开
标题翻译：安装垫
公开(公告)号：WO2011035116A1
公开(公告)日：2011-03-24
申请号：PCT/US2010/049271
申请日：2010-09-17
申请人： 3M INNOVATIVE PROPERTIES COMPANY , RUDEK, David M. , SCHMUCK, Eric
发明人： RUDEK, David M. , SCHMUCK, Eric
IPC分类号： F01N3/021 , F01N3/28
CPC分类号： F01N3/2864 , F01N3/0211 , F01N3/2857 , F01N2350/02 , F01N2450/02 , Y02T10/20 , Y10T29/49826
摘要： A mounting mat for a pollution control device is disclosed. The device comprises at least a first sheet and a second sheet and at least one holding means for holding the at least first and second sheets together. The holding means are adapted to (i) hold the at least first and second sheets together whilst allowing movement of the at least first and second sheets parallel to each other in the region where the holding means is positioned; and/or (ii) to break upon wrapping around a body thereby allowing movement of the at least first and second sheets parallel to each other in the region where the holding means is positioned. A pollution control device containing such a mat and method of making a pollution control device containing such a mat are also disclosed.
摘要翻译：公开了一种用于污染控制装置的安装垫。该装置至少包括第一片和第二片以及用于将至少第一片和第二片保持在一起的至少一个保持装置。保持装置适于（i）将至少第一和第二片材保持在一起，同时允许至少第一和第二片材在保持装置定位的区域中彼此平行移动; 和/或（ii）打破围绕身体的折叠，从而允许至少第一和第二片材在保持装置所在的区域中彼此平行地移动。还公开了含有这种垫子的污染控制装置和制造含有这种垫子的污染控制装置的方法。

7. 发明申请

WO2011035113A1 ILLUMINATION SYSTEM 审中-公开
标题翻译：照明系统
公开(公告)号：WO2011035113A1
公开(公告)日：2011-03-24
申请号：PCT/US2010/049264
申请日：2010-09-17
申请人： 3M INNOVATIVE PROPERTIES COMPANY , RUDEK, David M. , SCHMUCK, Eric
发明人： RUDEK, David M. , SCHMUCK, Eric
IPC分类号： G02B6/00
CPC分类号： G02B6/001
摘要： An illumination system incorporating an optical element such as an optical fibre is disclosed. The system comprises at least one light source and an optical element configured to emit visible light from a series of emission points located along its length when coupled to the light source. Each end of the optical element and the light source are held within a sleeve such that the optical element forms a continuous light guide. The optical element is further adapted to fit within a housing and to be held in tension within that housing, such that the optical element sits within the housing in a preferred orientation. Preferably, the light source is a light emitting diode.
摘要翻译：公开了一种结合光学元件如光纤的照明系统。该系统包括至少一个光源和被配置为当耦合到光源时沿着其长度定位的一系列发射点发射可见光的光学元件。光学元件和光源的每个端部保持在套筒内，使得光学元件形成连续的光导。光学元件还适于装配在壳体内并且保持在该壳体内的张力，使得光学元件以优选的方向位于壳体内。优选地，光源是发光二极管。

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