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1. 发明申请

WO2007016245A2 REPROGRAMMING OF ADULT OR NEONIC STEM CELLS AND METHODS OF USE 审中-公开
标题翻译：成人或正常干细胞的重编程和使用方法
公开(公告)号：WO2007016245A2
公开(公告)日：2007-02-08
申请号：PCT/US2006/029193
申请日：2006-07-28
申请人： VIVICELLS INTERNATIONAL, LLC , FITZSIMMONS, Frederick, J. , RICHARD, Daniel, D.
发明人： FITZSIMMONS, Frederick, J. , RICHARD, Daniel, D.
IPC分类号： A61K35/14 , C12N5/08
CPC分类号： C12N5/16 , A61K35/545 , C12N5/0696 , C12N2506/00
摘要： The present invention relates to methods of reprogramming adult stem cells or stem cells obtained from umbilical or placental cord blood or more preferably, the placeta or umbilical cord tissue itself or the amniotic fluid or amnion. The resulting stem cells and methods of using these stem cells represent additional aspects of the present invention. Stem cells according to the present invention, especially neonic stem cells (those obtained/reprogrammed from neonate stem cells), represent great potential in duplicating embryonic stem cell research without utilizing embryonic stems cells which have raised ethical and moral issues. The stem cells of the present invention which are reprogrammed are obtained from adults or from neonates without causing injury or death to a fetus in the case of embryonic stem cells and are non-controversial. In this sense, the present invention avoids many of the legal, ethical or moral considerations which have complicated the use of embryonic stem cells.
摘要翻译：本发明涉及对从脐带或胎盘脐带血获得的成体干细胞或干细胞进行重编程的方法，更优选涉及放置或脐带组织本身或羊水或羊膜。所得干细胞和使用这些干细胞的方法代表了本发明的另外方面。根据本发明的干细胞，特别是新生干细胞（从新生儿干细胞获得/重新编程的那些细胞），在复制胚胎干细胞研究中具有很大的潜力，而不利用已经引起伦理和道德问题的胚胎干细胞。重编程的本发明的干细胞得自成人或新生儿，在胚胎干细胞的情况下不会对胎儿造成伤害或死亡，并且是无争议的。从这个意义上说，本发明避免了使胚胎干细胞的使用复杂化的许多法律，伦理或道德考虑。

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