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1. 发明申请

WO2015042727A1 PREDICTING ACHIEVABLE DOSE DISTRIBUTION USING 3D INFORMATION AS AN INPUT 审中-公开
标题翻译：使用3D信息作为输入预测可实现的剂量分配
公开(公告)号：WO2015042727A1
公开(公告)日：2015-04-02
申请号：PCT/CH2014/000139
申请日：2014-09-30
申请人： VARIAN MEDICAL SYSTEMS INTERNATIONAL AG
发明人： KUUSELA, Esa , HARTMAN, Joona , NORD, Janne , BAGHAIE, Ramin
IPC分类号： A61N5/10
CPC分类号： A61N5/1039 , A61N5/1031 , A61N5/1045 , A61N5/1065 , A61N5/1071 , A61N2005/1041 , G06T7/344 , G06T2207/10104 , G06T2207/30096
摘要： Knowledge-based radiotherapy treatment planning is expanded to include spatial information from, for example, positron emission tomography (PET). Information that is specific to a patient is accessed. A prediction of a spatial dose distribution inside a target volume in the patient is determined using the patient-specific information as an input to a prediction model. The prediction model is established using training data that includes data resulting from applying other radiation treatment plans to other patients. The training data includes spatially distributed information indicating a level of activity in target volumes in the other patients (e.g., PET image data). A dose-volume histogram and associated three-dimensional dose distribution information based on the prediction are produced. The dose-volume histogram and the three-dimensional dose distribution information can be used to develop a radiation treatment plan for the patient.
摘要翻译：基于知识的放射治疗计划扩大到包括例如正电子发射断层扫描（PET）的空间信息。访问特定于患者的信息。使用患者特定信息作为预测模型的输入来确定患者中目标体积内的空间剂量分布的预测。使用训练数据建立预测模型，训练数据包括将其他辐射治疗计划应用于其他患者所产生的数据。训练数据包括指示其他患者的目标体积的活动水平的空间分布信息（例如，PET图像数据）。产生了基于预测的剂量体积直方图和相关联的三维剂量分布信息。剂量体积直方图和三维剂量分布信息可用于为患者制定放射治疗计划。

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