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    • 1. 发明申请
    • ARRAY INDEXING
    • 阵列指数
    • WO1997035256A1
    • 1997-09-25
    • PCT/GB1997000764
    • 1997-03-19
    • UNIVERSITY OF STRATHCLYDEMcGREGOR, Douglas, RobertCOCKSHOTT, William, Paul
    • UNIVERSITY OF STRATHCLYDE
    • G06F12/02
    • G06F12/0207
    • A method and apparatus for sequentially generating a set of addresses, defined over a plurality of indices, for a multi-dimensional array stored in a memory for the condition where at least one of the address indices is fixed, is performed by simple addition, OR-ing and AND-ing. An accumulator or counter initially holds an arbitrary binary value composed of a set of binary indices corresponding to the address indices. This binary value is logically OR-ed with a first mask value having binary indices selected in value in relation to the fixed address indices. The resultant is logically AND-ed with a second mask value having binary indices selected in value in relation to the fixed address indices, and this operation produces a first address of the set. The same resultant is incremented and the incremented value is delivered to the accumulator for the cycle to be repeated.
    • 一种方法和装置,用于通过简单的加法来执行存储在存储器中的至少一个地址索引固定的状态的多个索引定义的地址集合,OR 和和。 累加器或计数器最初保存由对应于地址索引的一组二进制索引组成的任意二进制值。 该二进制值与具有相对于固定地址索引的值选择的二进制索引的第一掩码值进行逻辑或运算。 所得到的结果与具有相对于固定地址索引值的二进制索引的第二掩码值进行逻辑AND编辑,并且该操作产生该集合的第一地址。 相同的结果被递增,并且递增的值被递送到累加器以用于要重复的周期。
    • 2. 发明申请
    • DATABASES
    • WO1997032263A1
    • 1997-09-04
    • PCT/GB1997000578
    • 1997-02-28
    • UNIVERSITY OF STRATHCLYDEMcGREGOR, Douglas, RobertCOCKSHOTT, William, PaulWILSON, John, Nugent
    • UNIVERSITY OF STRATHCLYDE
    • G06F17/30
    • G06F17/30952Y10S707/99942
    • A computer database for storing information in tuple form wherein each tuple comprises fields with corresponding fields in the tuples constituting a column, generates for each data domain a domain dictionary which matches each distinct data value in that domain with a corresponding distinct token, and stores each domain dictionary. A tokenised store for each data field column is created. All of the tokens for a domain are initially of the same size being substantially the minimum size necessary to provide the required plurality of distinct tokens for the initial size of that domain. When further tuples are received for storage for each field of the tuple the data value is compared in the corresponding domain dictionary and if no match is found a new token within the existing token size is generated and added to the domain dictionary but if all tokens within the existing token size are utilised a new token is generated having a size which is at least 1-bit wider than previously, such broadened tokens being entered into a new tokenised store for that column.
    • 一种用于以元组形式存储信息的计算机数据库,其中每个元组包括在元组中构成列的对应字段的字段,为每个数据域生成与该域中的每个不同数据值与相应的不同令牌相匹配的域字典, 域名词典。 创建每个数据字段列的令牌化存储。 域的所有令牌最初具有相同的大小,实质上是为该域的初始大小提供所需的多个不同令牌所必需的最小大小。 当为元组的每个字段接收进一步的元组存储时,在对应的域字典中比较数据值,并且如果找不到匹配,则生成现有令牌大小内的新令牌并将其添加到域字典中,但是如果所有令牌在 使用现有的令牌大小,生成具有比以前至少1位宽的大小的新令牌,这样的扩展令牌被输入到该列的新的令牌化存储。
    • 4. 发明申请
    • RECOGNITION SYSTEM
    • 识别系统
    • WO1994024636A1
    • 1994-10-27
    • PCT/GB1994000777
    • 1994-04-13
    • UNIVERSITY OF STRATHCLYDELAMBERT, Robert, BartholemewFRYER, Richard, JohnCOCKSHOTT, William, Paul
    • UNIVERSITY OF STRATHCLYDE
    • G06F15/80
    • G06K9/62G06N3/088
    • A recognition system of the self-organising artificial neural network type is arranged to classify input data according to stored categories which have been determined by a training process. In the training process the initial category representations are selectively iteratively updated in response to a series of training patterns and in accordance with a competitive learning routine. This routine uses measures of category utilisation based on the proportion of all inputs received over a representative period, particularly long term utilisation and short term utilisation, to ensure that all available categories will be used and that the system is stable. The training rate which determines the amount of modification to a category representation at an up-date is local to each category and is based upon the maturity of the category and on the similarity measure between the internal representative pattern and the training input so that the training duration can be minimised. A user-operated selectively-operable suggestion learning input is provided to each category to modify the training process or to enable secondary training to proceed during classification of input data using that input data as the training patterns. The categories are represented by multiple reference patterns with respective importance values from which the degree of compatibility between an input and a category is computed taking into account the importance values.
    • 安排自组织人工神经网络类型的识别系统根据已经通过训练过程确定的存储类别对输入数据进行分类。 在训练过程中,响应于一系列训练模式并根据竞争性学习例程,初始类别表示被选择性迭代地更新。 这个例行程序采用基于在代表期间收到的所有投入的比例,特别是长期利用率和短期利用率的比例来确定所有可用类别将被使用,并且系统是稳定的。 确定更新类别代表的修改量的培训率是每个类别的本地化,并且基于类别的成熟度和内部代表模式与培训输入之间的相似性度量,以便训练 持续时间可以最小化。 提供用户操作的选择性可操作的建议学习输入到每个类别以修改训练过程,或者使用该输入数据作为训练模式来分类输入数据期间进行辅助训练。 类别由具有各自的重要性值的多个参考模式表示,从重要性值考虑重要性值来计算输入和类别之间的兼容性程度。
    • 6. 发明申请
    • METHOD AND APPARATUS FOR SIMULATION OF A PHYSICAL PROCESS
    • 用于模拟物理过程的方法和装置
    • WO1991008560A1
    • 1991-06-13
    • PCT/GB1990001841
    • 1990-11-27
    • UNIVERSITY OF STRATHCLYDEMILNE, George, JohnstoneCOCKSHOTT, William, Paul
    • UNIVERSITY OF STRATHCLYDE
    • G09B23/12
    • G09B23/12G06F17/5009G09B23/06G09B23/186
    • In the simulation of a spatially-extended physical process the complete spatial extent of which is defined by a multiplicity of parameters (A), each parameter (A) is represented with a multi-state distinguished sequential digital logic circuit (B) the possible states of which represent the possible states of the pertaining parameter (A). The interaction of each pair of parameters (A) is represented with an interconnection (C) between the pertaining circuits (B). Each logic circuit (B) is initially established in a known state and thereafter at least one circuit (B) is pulsed to cause evolution of the circuits (B) through some or all of their possible states. The states of certain circuits (B) are determined intermittently as a mesure of the corresponding states of the parameters (A).
    • 在空间扩展的物理过程的模拟中,其完整的空间范围由多个参数(A)定义,每个参数(A)由多状态区分顺序数字逻辑电路(B)表示,可能的状态 其中表示相关参数(A)的可能状态。 每对参数(A)的相互作用由相关电路(B)之间的互连(C)表示。 每个逻辑电路(B)最初在已知状态下被建立,此后至少一个电路(B)被脉冲以引起电路(B)通过其可能状态的一些或全部的演变。 某些电路(B)的状态被间歇地确定为参数(A)的对应状态的计量。
    • 8. 发明申请
    • DATA COMPRESSION
    • 数据压缩
    • WO1997016026A1
    • 1997-05-01
    • PCT/GB1996002593
    • 1996-10-22
    • UNIVERSITY OF STRATHCLYDECOCKSHOTT, Paul, WilliamMcGREGOR, Douglas, RobertFRYER, Richard, JohnLAMBERT, Robert, Bartholemew
    • UNIVERSITY OF STRATHCLYDE
    • H04N07/26
    • H04N19/94H04N19/105H04N19/15H04N19/154H04N19/176H04N19/192H04N19/61
    • A method of compressing an image frame composed of an array of pixels in the form of digital electrical signals, the method comprising the steps of: (a) providing a reference image as a first approximation to the original image to be compressed; (b) dividing the original image into patches of one or more sizes; (c) for each patch, determining a compressed encoding of the data contained therein where the compressed encoding can be uncompressed to provide an approximation to the patch; (d) selecting that one of the compressed encodings which, when uncompressed and added to the reference image, gives the biggest improvement therein relative to the original image; (e) adding the selected compressed encoding in uncompressed form to the reference image and in compressed form to a compressed representation of the original image; and (f) recursively repeating step (d) for the remaining compressed encodings until either a desired quality level of the reference image or a maximum data size of the compressed representation is achieved.
    • 一种压缩由数字电信号形式的像素阵列组成的图像帧的方法,所述方法包括以下步骤:(a)提供参考图像作为要压缩的原始图像的第一近似值; (b)将原始图像划分成一个或多个尺寸的贴片; (c)对于每个贴片,确定其中包含的数据的压缩编码,其中压缩编码可以被解压缩以提供对贴片的近似; (d)选择当未压缩并添加到参考图像时,相对于原始图像给出最大的改进的压缩编码之一; (e)以未压缩形式将所选压缩编码添加到参考图像并以压缩形式添加到原始图像的压缩表示; 以及(f)对剩余的压缩编码递归地重复步骤(d),直到达到参考图像的期望质量水平或压缩表示的最大数据大小。
    • 9. 发明申请
    • IMPROVED NEURAL NETWORK
    • 改进的神经网络
    • WO1998022884A1
    • 1998-05-28
    • PCT/GB1997003138
    • 1997-11-21
    • UNIVERSITY OF STRATHCLYDESORAGHAN, John, JamesHUSSAIN, Amir
    • UNIVERSITY OF STRATHCLYDE
    • G06F15/80
    • G06K9/6273G06N3/063
    • A neural network of the radial basis function type has a single hidden layer function generator (12) and an output layer (40). The function generator (12) receives one or more mapping inputs (10) and generates a plurality of terms (14) from each mapping input, said terms including at least one trigonometric term and being free of Gaussian and Sigmoidal terms. The output layer (40) weights the terms, sums the weighted terms to produce a predicted output (36). The predicted output is compared with the actual value of the predicted output when this becomes known and an analyzer (34) consequently drives a weight setting controller (20) to adjust the weight values for use in the next prediction.
    • 径向基函数类型的神经网络具有单个隐层函数发生器(12)和输出层(40)。 函数发生器(12)接收一个或多个映射输入(10)并且从每个映射输入产生多个项(14),所述项包括至少一个三项项,并且没有高斯和S形项。 输出层(40)对项进行加权,将加权项加起来以产生预测输出(36)。 当已知该预测输出时,将预测输出与预测输出的实际值进行比较,并且分析器(34)因此驱动权重设置控制器(20)来调整用于下一预测中的权重值。
    • 10. 发明申请
    • DETECTION OF NUCLEIC ACIDS AND NUCLEIC ACID UNITS
    • 检测核酸和核酸单位
    • WO1997005280A1
    • 1997-02-13
    • PCT/GB1996001830
    • 1996-07-25
    • UNIVERSITY OF STRATHCLYDEGRAHAM, DuncanLINACRE, Adrian, Matthew, ThorntonMUNRO, Calum, HughSMITH, William, EwanWATSON, Nigel, DeanWHITE, Peter, Cyril
    • UNIVERSITY OF STRATHCLYDE
    • C12Q01/68
    • C12Q1/6816G01N21/658Y10T436/24C12Q2565/632
    • The invention relates to the detection of target nucleic acids or nucleic acid units in a sample, by obtaining a SER(R)S spectrum for a SER(R)S-active complex containing, or derived directly from, the target. The complex includes at least a SER(R)S-active label, and optionally a target binding species containing a nucleic acid or nucleic acid unit. In this detection method, the concentration of the target present in the SER(R)S-active complex, or of the nucleic acid or unit contained in the target binding species in the SER(R)S-active complex, is no higher than 10 moles per litre. Additionally or alternatively, one or more of the following features may be used with the method: i) the introduction of a polyamine; ii) modification of the target, and/or of the nucleic acid or nucleic acid unit contained in the target binding species, in a manner that promotes or facilitates its chemi-sorption onto a SER(R)S-active surface; iii) inclusion of a chemi-sorptive functional group in the SER(R)S-active label. The invention also provides SER(R)S-active complexes for use in such a method, a kit for use in carrying out the method or preparing the complexes and a method for sequencing a nucleic acid which comprises the use of the detection method to detect at least one target nucleotide or sequence of nucleotides within the acid.
    • 本发明涉及通过获得含有或直接衍生自靶的SER活性复合物的S(S)活性复合物,来检测样品中的靶核酸或核酸单元。 所述复合物包括至少一种SER(R)S-活性标记,以及任选的含有核酸或核酸单元的靶结合物质。 在该检测方法中,SER(R)S-活性复合物中存在的靶标或SER(S)活性复合物中目标结合物中所含的核酸或单元的浓度不高于 10〜10摩尔/升。 另外或替代地,可以使用以下方法中的一个或多个以下特征:i)引入多胺; ii)以促进或促进其对SER活性表面的化学吸附的方式修饰靶,和/或包含在靶结合物种中的核酸或核酸单元; iii)在SER(R)S活性标签中包含化学吸附官能团。 本发明还提供了用于这种方法的SER(R)S-活性复合物,用于实施该方法或制备复合物的试剂盒和核酸测序方法,其包括使用检测方法检测 酸中的至少一个靶核苷酸或核苷酸序列。