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1. 发明申请

WO2010064890A1 A SUPERCRITICAL FLUID EXTRACTION PROCESS OF KENAF SEEDS 审中-公开
标题翻译： KENAF种子的超临界流体萃取过程
公开(公告)号：WO2010064890A1
公开(公告)日：2010-06-10
申请号：PCT/MY2009/000113
申请日：2009-08-07
申请人： UNIVERSITI PUTRA MALAYSIA , ISMAIL, Maznah , CHAN, Kim, Wei , GHAFAR, Siti, Aisyah
发明人： ISMAIL, Maznah , CHAN, Kim, Wei , GHAFAR, Siti, Aisyah
IPC分类号： C11B1/10 , B01D11/02
CPC分类号： C11B1/104 , B01D11/0203 , B01D11/0288 , C11B3/006
摘要： The present invention provides a supercritical fluid extraction (SFE) process for extracting oil of kenaf seed (Hibiscus cannabinus L), wherein the SFE process utilises a supercritical fluid and is conducted in a pressure ranging from 200 to 600 bars with a temperature ranging from 40 to 80 °C.
摘要翻译：本发明提供了一种用于提取洋麻种子（木槿L）的油的超临界流体萃取（SFE）方法，其中SFE方法利用超临界流体，并且在200至600巴的压力范围内进行，温度范围为40 至80℃。

2. 发明申请

WO2010064891A1 EXTRACTIONS OF FIXED OIL AND THYMOQUINONE RICH FRACTIONS (TQRF) 审中-公开
标题翻译：固定油和三羟甲基纤维素（TQRF）的提取
公开(公告)号：WO2010064891A1
公开(公告)日：2010-06-10
申请号：PCT/MY2009/000115
申请日：2009-08-07
申请人： UNIVERSITI PUTRA MALAYSIA , ISMAIL, Maznah , AL-NAQEEB, Ghanya , CHAN, Kim Wei , ADNAN, Raja, Nurzatul, Efa
发明人： ISMAIL, Maznah , AL-NAQEEB, Ghanya , CHAN, Kim Wei , ADNAN, Raja, Nurzatul, Efa
IPC分类号： C11B1/10 , B01D11/02
CPC分类号： C11B1/104 , A23L33/105 , B01D11/0203 , B01D11/0288 , C11B3/006
摘要： The present invention reported that SFE is suitable for Nigella sativa seeds oil extraction and fractionation. TQRF that were produced through SFE extractions (600 bars/40 °C) and fractionations (100-200 bars/40-60 °C) possessed high level of TQ and antioxidant activity. SFE fractionation efficiently concentrates the TQ content and antioxidant activity of Nigella sativa seeds oil in short time and low cost manners without using any hazardous organic solvents.
摘要翻译：本发明报道SFE适用于黑藻种子提取和分馏。通过SFE提取（600巴/ 40℃）和分馏（100-200巴/ 40-60℃）产生的TQRF具有高水平的TQ和抗氧化活性。 SFE分馏在短时间和低成本的情况下有效地浓缩了Nigella sativa种子油的TQ含量和抗氧化活性，而不使用任何有害有机溶剂。

3. 发明申请

WO2010050794A8 CARDIOPROTECTIVE EFFECTS OF NUTRACEUTICALS ISOLATED FROM NIGELLA SATIVA SEEDS 审中-公开
公开(公告)号：WO2010050794A8
公开(公告)日：2010-05-06
申请号：PCT/MY2009/000114
申请日：2009-08-07
申请人： UNIVERSITI PUTRA MALAYSIA , ISMAIL, Maznah , AL-NAQEEB, Ghanya
发明人： ISMAIL, Maznah , AL-NAQEEB, Ghanya
IPC分类号： A61K36/71 , A61P9/00 , A61P39/06 , A61K9/14 , A61K9/107
摘要： This invention relates to a rich antioxidant nutraceuticals prepared from Nigella sativa seeds for the treatment and prevention of hypercholesterolemia. These nutraceuticals when taken enterally has shown successfully to have hypocholesterolmic, antiatherogenic and antioxidant activities using in vitro and in vivo study. The invention provides a clear explanation on the molecular mechanism by which nutraceuticals prepared from the Nigella sativa seeds exerted its hypocholesterolemic effect.

4. 发明申请

WO2012161559A2 A USE OF A COMPOSITION COMPRISING OF ACYLATED STERYL GLUCOSIDE IN THE MANUFACTURE OF A PRODUCT 审中-公开
标题翻译：在产品制造中使用含有ACYLATED STERYL GLUCOSIDE的组合物的使用
公开(公告)号：WO2012161559A2
公开(公告)日：2012-11-29
申请号：PCT/MY2012/000091
申请日：2012-04-26
申请人： UNIVERSITI PUTRA MALAYSIA , ISMAIL, Maznah , IMAM, Mustapha Umar , MUSA, Siti Nor Asma
发明人： ISMAIL, Maznah , IMAM, Mustapha Umar , MUSA, Siti Nor Asma
IPC分类号： C07H15/24 , C07J3/00 , A61K31/704 , A61K31/56 , A61P7/00
CPC分类号： A61K31/7004 , A61K31/704 , A61K36/899 , A61K45/06 , C07J17/005
摘要： The present invention relates to a use of a composition in the manufacture of a product for regulating a plurality of genes consisting of phosphoenolpyruvate carboxykinase-1, fructose-1,6-bisphosphatase, xenobiotic metabolism, low-density lipoprotein receptor, apolipoprotein-A1, superoxide dismutase-2, and catalase, characterised in that: the composition comprising acylated steryl glucoside.
摘要翻译：本发明涉及组合物在制造产品中的用途，所述产品用于调节由磷酸烯醇丙酮酸羧激酶-1，果糖-1,6-二磷酸酶，异生物代谢，低密度脂蛋白受体，载脂蛋白-A1，超氧化物歧化酶-2和过氧化氢酶，其特征在于：所述组合物包含酰化的甾醇葡糖苷。

5. 发明申请

WO2010050793A1 USES OF CURCULIGO LATIFOLIA (C. LATIFOLIA) EXTRACTS 审中-公开
标题翻译： CURCULIGO LATIFOLIA（C. LATIFOLIA）提取物的使用
公开(公告)号：WO2010050793A1
公开(公告)日：2010-05-06
申请号：PCT/MY2009/000112
申请日：2009-08-07
申请人： UNIVERSITI PUTRA MALAYSIA , ISMAIL, Maznah , ISHAK, Nur, Akmal , HAMID, Muhajir
发明人： ISMAIL, Maznah , ISHAK, Nur, Akmal , HAMID, Muhajir
IPC分类号： A61K36/88 , A61P3/10 , A61P9/10 , A61P9/00
CPC分类号： A61K36/88 , A61K36/896 , A61K2236/331
摘要： The present invention relates to Curculigo latifolia (C. latifolia) extracts, wherein the extracts extracted from different parts of a plant such as fruits, roots and leaves, individually and in any combinations thereof, characterized in that the extracts are used as an agent for treating and preventing metabolic disorder diseases such as diabetes mellitus, obesity, cardiovascular, and atherosclerosis.
摘要翻译：本发明涉及花椰菜（C. latifolia）提取物，其中从植物的不同部分提取的提取物，例如水果，根和叶，其单独和任意组合，其特征在于，提取物用作治疗和预防代谢障碍疾病如糖尿病，肥胖，心血管和动脉粥样硬化。

6. 发明申请

WO2012134262A3 A METHOD FOR EXTRACTING PROTEIN FROM PECTIN RICH PLANT MATERIAL 审中-公开
公开(公告)号：WO2012134262A3
公开(公告)日：2012-10-04
申请号：PCT/MY2012/000044
申请日：2012-03-07
申请人： UNIVERSITI PUTRA MALAYSIA (U.P.M.) , HAJI.AHMAD, Zalinah , RASTEGARI, Elham , SPENCER, David, Farringdon , ISMAIL, Maznah
发明人： HAJI.AHMAD, Zalinah , RASTEGARI, Elham , SPENCER, David, Farringdon , ISMAIL, Maznah
IPC分类号： C07K14/415 , C07K1/12 , C12P21/06 , G01N33/68
摘要： The present invention relates to methods for extracting protein from plant material which is characterized by a high content of interfering compounds, specifically abundant polysaccharides like pectin. The inventive method applies a pectolytic treatment in preparation of the plant material sample prior to protein extraction. This optimized method results in high quality protein extracts compatible with further sensitive proteomic analyses specifically methods like two dimensional gel electrophoresis or mass spectrometry. The present invention further relates to the protein extracts obtained by the inventive method and the use of the inventive method in the preparation of protein samples. Also a protein extraction kit is disclosed for conducting the inventive method, as well as the use of the protein extraction kit in protein analysis and proteomics.

7. 发明申请

WO2015076667A1 A COMPOSITION FOR MANAGING MENOPAUSE 审中-公开
标题翻译：用于管理MENOPAUSE的组合物
公开(公告)号：WO2015076667A1
公开(公告)日：2015-05-28
申请号：PCT/MY2014/050008
申请日：2014-11-19
申请人： UNIVERSITI PUTRA MALAYSIA
发明人： ISMAIL, Maznah , MUHAMMAD SANI, Ismaila , MAHMUD, Rozi , ABU BAKAR@ZAKRIYA, Zuki
IPC分类号： A61K36/899 , A23L1/30 , A61K31/197 , A61K31/575 , A61P5/30 , A61P9/00 , A61P19/10 , A61P29/00 , A61P39/06
CPC分类号： A61K31/575 , A23L33/105 , A61K31/197 , A61K31/704 , A61K36/899 , Y02A50/395
摘要： The present invention relates to a composition for managing menopause in a human or animal body, characterized in that said composition comprises a germinated brown rice derived compound.
摘要翻译：本发明涉及一种用于管理人或动物体内更年期的组合物，其特征在于所述组合物包含发芽的糙米衍生化合物。

8. 发明申请

WO2014209101A2 METHOD OF OBTAINING GELATIN FROM AQUATIC ANIMALS 审中-公开
标题翻译：从水生动物获得凝胶的方法
公开(公告)号：WO2014209101A2
公开(公告)日：2014-12-31
申请号：PCT/MY2014/000191
申请日：2014-06-25
申请人： UNIVERSITI PUTRA MALAYSIA
发明人： MD. YUSOFF, Fatimah , BAKAR, Jamilah , BASRI, Mahiran , ISMAIL, Maznah , KHONG, Mun Hoe Nicholas
IPC分类号： C07K14/78
CPC分类号： A61K35/614 , A61K38/00 , C07K14/461
摘要： The present invention relates to a simple, cost and time effective process of producing gelatin from aquatic animal tissue, which comprises the steps of: (a) treating the cleaned and dehydrated aquatic animal tissue with salt solution, preferably of less than 1.0M; (b) treating biomass obtained after Step (a) with aqueous alkali; (c) washing the alkali-treated biomass with water until the washing water is substantially neutral; (d) treating the neutralized biomass from step (c) with aqueous acid with continuous stirring for up to 4 h; (e) washing the acid-treated biomass with water until the washing water is substantially neutral; (f) extracting with water at pH less or equal to 2 at temperatures in the range of 45°C to 65°C for 6 to 8 h; (g) dialysing the gelatin obtained from step (f) against neutral buffer or deionised distilled water for at least 24 hours; (h) removal of water from the gelatin obtained until moisture content of the resultin gelatine is less than 13%. The process provides a gelatine having excellent properties, such as quality, appearance, gel strength etc., suitable for use in pharmaceutical, cosmeceutical, food and photography products.
摘要翻译：本发明涉及从水生动物组织制备明胶的简单，成本和时间有效的方法，其包括以下步骤：（a）用优选小于1.0M的盐溶液处理清洁和脱水的水生动物组织; （b）用碱水处理步骤（a）后获得的生物质; （c）用水洗涤碱处理的生物质，直到洗涤水基本上为中性; （d）用连续搅拌的酸水溶液处理来自步骤（c）的中和的生物质达4小时; （e）用水洗涤酸处理的生物质，直到洗涤水基本上为中性; （f）在45℃至65℃的温度下，用pH小于或等于2的水萃取6至8小时; （g）将从步骤（f）获得的明胶对中性缓冲液或去离子蒸馏水透析至少24小时; （h）从明胶中除去水，直到明胶的含水量低于13％。该方法提供了具有优异性能的明胶，如质量，外观，凝胶强度等，适用于制药，药妆，食品和摄影产品。

9. 发明申请

WO2015012682A2 A METHOD FOR EXTRACTING COLLAGEN FROM AQUATIC ANIMALS, COLLAGEN AND PRODUCTS CONTAINING IT 审中-公开
标题翻译：从水产动物，胶原蛋白和含有它的产品中提取胶原蛋白的方法
公开(公告)号：WO2015012682A2
公开(公告)日：2015-01-29
申请号：PCT/MY2014/000190
申请日：2014-06-25
申请人： UNIVERSITI PUTRA MALAYSIA
发明人： MD. YUSOFF, Fatimah , BAKAR, Jamilah , BASRI, Mahiran , ISMAIL, Maznah , KHONG, Mun Hoe Nicholas
IPC分类号： C07K1/14
CPC分类号： C07K1/145
摘要： The present invention provides an improved process for extracting collagen from aquatic animals, comprising alkaline treatment, followed by acidic treatment in combination with an orderly sequence of physical and/or mechanical treatments and precipitation of collagen using a salt solution. The process increases the yield and quality of the collagen while decreasing the production time and is more cost-effective than the processes known heretofore. The invention further includes the obtained collagen and products containing it.
摘要翻译：本发明提供了一种用于从水生动物中提取胶原的改进方法，包括碱处理，随后酸化处理以及物理和/或机械处理的有序序列以及使用盐沉淀胶原蛋白解。该方法增加了胶原蛋白的产量和质量，同时减少了生产时间，并且比迄今已知的方法更具成本效益。本发明还包括获得的胶原蛋白和含有它的产品。

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