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1. 发明申请

WO2006122232A3 METHODS AND APPARATUS FOR IMAGING WITH MAGNETIC INDUCTION 审中-公开
标题翻译：用于磁感应成像的方法和装置
公开(公告)号：WO2006122232A3
公开(公告)日：2007-11-15
申请号：PCT/US2006018207
申请日：2006-05-10
申请人： UNIV MINNESOTA , HE BIN , XU YUAN , LI XU
发明人： HE BIN , XU YUAN , LI XU
IPC分类号： A61B5/05
CPC分类号： G01R33/4808 , A61B5/0093 , A61B8/00
摘要： An apparatus includes a magnetic energy source to provide a magnetic signal and a detector to detect an acoustic energy signal from a sample stimulated by the magnetic energy signal. A method includes applying a magnetic signal to a biological sample, detecting an acoustic signal from the sample, and processing the acoustic signal to determine the electrical impedance distribution of the sample, and identify disease in the biological sample. A method includes applying a magnetic signal to a sample, detecting a magnetic or electrical signal within the sample, and processing the magnetic or electrical signal to reconstruct electrical impedance distribution of the sample.
摘要翻译：一种装置包括提供磁信号的磁能源和用于从由磁能信号刺激的样本中检测声能信号的检测器。一种方法包括向生物样品施加磁信号，检测来自样品的声信号，以及处理声信号以确定样品的电阻抗分布，并识别生物样品中的疾病。一种方法包括对样品施加磁信号，检测样品内的磁信号或电信号，以及处理磁信号或电信号以重构样品的电阻抗分布。

2. 发明申请

WO2004009664A3 BIODEGRADABLE TRIBLOCK COPOLYMERS, SYNTHESIS METHODS THEREFOR, AND HYDROGELS AND BIOMATERIALS MADE THERE FROM 审中-公开
标题翻译：可生物降解的三嵌段共聚物，其合成方法，以及水合物和生物材料
公开(公告)号：WO2004009664A3
公开(公告)日：2004-08-12
申请号：PCT/US0322561
申请日：2003-07-18
申请人： OMEROS CORP , INST MATERIALS RESEARCH & ENG , LI JUN , LI XU , NI XIPING , LEONG KAM W
发明人： LI JUN , LI XU , NI XIPING , LEONG KAM W
IPC分类号： A61F2/00 , A61K9/00 , A61K9/51 , A61K47/32 , A61K47/34 , A61K47/48 , A61L27/34 , A61L27/52 , A61L27/54 , A61L31/10 , A61L31/14 , A61L31/16
CPC分类号： A61K9/0024 , A61K9/1075 , A61K9/5153 , A61K47/32 , A61K47/34 , A61K47/6903 , A61K47/6951 , A61L27/34 , A61L27/52 , A61L27/54 , A61L31/10 , A61L31/145 , A61L31/16 , A61L2300/602 , A61L2300/802 , B82Y5/00
摘要： A drug delivery system that includes a hydrogel formed from cyclodextrin and an amphiphilic copolymer that includes an A polymer block comprising a poly(alkylene oxide) and a B polymer block comprising a poly(hydroxyalkanoate), and a therapeutically effective amount of at least one therapeutic agent intimately contained within the hydrogel. In one preferred embodiment of the invention, the A polymer block 10 is poly(ethylene oxide) (PEO) and the B polymer block is poly[(R)-3-hydroxybutyrate] (PHB), and the copolymer is the triblock ABA copolymer PEO-PHB-PEO. A method of synthesizing the amphiphilic triblock copolymer is also provided.
摘要翻译：一种药物递送系统，其包括由环糊精形成的水凝胶和包含聚合物嵌段的两亲性共聚物，所述聚合物嵌段包含聚（环氧烷）和包含聚（羟基链烷酸酯）的B聚合物嵌段，以及治疗有效量的至少一种治疗代谢物密切包含在水凝胶内。在本发明的一个优选实施方案中，A聚合物嵌段10是聚（环氧乙烷）（PEO），B聚合物嵌段是聚[（R）-3-羟基丁酸酯]（PHB），共聚物是三嵌段ABA共聚物 PEO-PHB-PEO。还提供了合成两亲性三嵌段共聚物的方法。

3. 发明申请

WO9926337A9 METHODS AND APPARATUS FOR AUTOMATICALLY SYNCHRONIZING AND REGULATING VOLUME IN AUDIO COMPONENT SYSTEMS 审中-公开
标题翻译：用于在音频组件系统中自动同步和调节音量的方法和设备
公开(公告)号：WO9926337A9
公开(公告)日：1999-12-23
申请号：PCT/US9824314
申请日：1998-11-13
申请人： MICROTEK LAB INC , LI XU , RUBIN ELLIOT M , SHOU XIAOFENG
发明人： LI XU , RUBIN ELLIOT M , SHOU XIAOFENG
IPC分类号： H03G5/16 , H04R5/00 , H03G3/00
CPC分类号： H04S7/30 , H03G5/165 , H04S2400/13
摘要： A signal regulator (50) regulates an auxiliary signal (A) based upon a primary signal (P') scaled by an external amplifier. The signal regulator (50) receives the primary signal with an unscaled level (P). Processing circuitry (54) monitors the unscaled level of the primary signal. The primary signal (at 56) is then output to the external amplifier for scaling, either by amplification or attenuation. The primary signal with a scaled level (P') is fed back to the signal regulator (50) from the amplifier. The processing circuitry (54) monitors the scaled level of the primary signal (P') from the amplifier, and then generates a gain factor (G) based upon the unscaled level (P) and scaled level of the primary signal (P'). An auxiliary signal (A) is received by the signal regulator (50). Adjusting circuitry (62) adjusts a level of the auxiliary signal based upon the gain factor (G). The auxiliary signal with the adjusted level (A') is then provided to an external component, for example, a loudspeaker.
摘要翻译：信号调节器（50）基于由外部放大器缩放的主信号（P'）来调节辅助信号（A）。信号调节器（50）接收具有未缩放级别（P）的主信号。处理电路（54）监视主信号的未缩放的电平。然后将主信号（在56处）输出到外部放大器以通过放大或衰减进行缩放。具有定标电平（P'）的主信号从放大器反馈到信号调节器（50）。处理电路（54）监测来自放大器的主信号（P'）的经缩放的电平，然后基于未经缩放的电平（P）和主信号（P'）的经缩放的电平来生成增益因子（G）。信号调节器（50）接收辅助信号（A）。调整电路（62）根据增益因子（G）调整辅助信号的电平。然后将具有调节后的电平（A'）的辅助信号提供给外部部件，例如扬声器。

4. 发明申请

WO2005049058A8 RADIX SALVIAE MILTIORRHIZAE, EXTRACT AND COMPOSITION THEREOF FOR THE TREATMENT OF THE ASPIRIN RESISTANCE DISEASES 审中-公开
标题翻译： RADIX SALVIAE MILTIORRHIZAE，其治疗抗甲状腺疾病的提取物和组合物
公开(公告)号：WO2005049058A8
公开(公告)日：2005-08-11
申请号：PCT/CN2004000989
申请日：2004-08-26
申请人： TIANJIN TASLY PHARMACEUTICAL , YAN XIJUN , WU NAIFENG , YE ZHENGLIANG , LI XU , GUO ZHIXIN , ZHENG JUN , ZHAO NA
发明人： YAN XIJUN , WU NAIFENG , YE ZHENGLIANG , LI XU , GUO ZHIXIN , ZHENG JUN , ZHAO NA
IPC分类号： A61K36/00 , A61K36/185 , A61K36/258 , A61K36/537 , A61K45/06 , A61P9/00 , A61K35/78
CPC分类号： A61K36/537 , A61K36/185 , A61K36/258 , A61K45/06 , A61K2300/00
摘要： The present invention relates to the uses of Radix Salviae Miltiorrhizae, extract and composition thereof in the treatment of the aspirin resistance diseases, especially in the treatment of the aspirin resistance angiocardiopathy with drop pills of Radix Salviae miltiorrhizae.
摘要翻译：本发明涉及丹参，其提取物及其组合物在治疗阿司匹林耐药性疾病中的应用，特别是在使用丹参滴丸治疗阿司匹林抵抗性心血管病。

5. 发明申请

WO2008051349A3 IMPROVED ETHANOL PRODUCT I ON IN FERMENTATION OF MIXED SUGARS CONTAINING XYLOSE IN THE PRESENCE OF SUGAR ALCOHOLS 审中-公开
标题翻译：改进的乙醇产品I在糖乳液存在下发酵中含有XYLOSE的混合糖
公开(公告)号：WO2008051349A3
公开(公告)日：2008-08-07
申请号：PCT/US2007020946
申请日：2007-09-28
申请人： DU PONT , MIDWEST RESEARCH INST , VIITANEN PAUL V , MCCUTCHEN CAROL M , LI XU , EMPTAGE MARK , CAIMI PERRY G , ZHANG MIN , CHOU YAT-CHEN , FRANDEN MARY ANN
发明人： VIITANEN PAUL V , MCCUTCHEN CAROL M , LI XU , EMPTAGE MARK , CAIMI PERRY G , ZHANG MIN , CHOU YAT-CHEN , FRANDEN MARY ANN
IPC分类号： C12N1/00
CPC分类号： C12N1/20 , C12P7/065 , C12R1/01 , Y02E50/16 , Y02E50/17
摘要： Xylose-utilizing Z. mobilis strains were found to have improved ethanol production when grown in medium containing mixed sugars including xylose if sorbitol or mannitol was included in the medium. The effect was seen in concentrations of mixed sugars where no growth lag period occurs, as well as in higher sugars concentrations.
摘要翻译：当发现含木糖的运动发酵单胞菌菌株在含有木糖的混合糖的培养基中生长时，如果在培养基中包含山梨糖醇或甘露醇，则发现其具有改善的乙醇生产。在没有生长滞后期的混合糖的浓度以及较高的糖浓度下观察到效果。

6. 发明申请

WO03099759A8 PREPARATION AND APPLICATION OF TRANSHINTOTALPHENOLIC ACID 审中-公开
标题翻译：超临界酚酸的制备与应用
公开(公告)号：WO03099759A8
公开(公告)日：2004-03-11
申请号：PCT/CN0300375
申请日：2003-05-21
申请人： TIANJIN TASLY PHARMACEUTICAL , WEI FENG , YUE HONGSHUI , LI DEKUN , SUN JIANGXIAO , YE ZHENGLIANG , LI XU
发明人： WEI FENG , YUE HONGSHUI , LI DEKUN , SUN JIANGXIAO , YE ZHENGLIANG , LI XU
IPC分类号： A61K36/53 , A61K31/19 , A61K31/192 , A61K31/34 , A61K36/00 , A61P1/08 , A61P1/16 , A61P1/18 , A61P3/00 , A61P3/10 , A61P7/02 , A61P9/00 , A61P9/10 , A61P11/00 , A61P13/12 , A61P19/00 , A61P25/02 , A61P25/06 , A61P25/28 , A61P27/02 , A61P39/00 , A61P39/06 , C07C59/52 , C07C67/56 , C07C67/58 , C07C69/675 , C07D307/84
CPC分类号： A61K31/34 , A61K31/19 , C07D307/84
摘要： A process for preparing tanshintotalphenolic acid and the use of the product are disclosed. The process comprises: tanshin is hot-extracted with water, the extract is separated and refined by polyamide column and macroporous adsorption resin column, and lyophilized to obtain tanshintotalphenolic acid. The yield of the final end product is more than 4 percent based on the amount of crude drug and the content of totalphenolic acid is more than 80 percent. The tanshintotalphenolic acid obtained can be used as the medicine for preventing and treating cerebrovascular and cardiovascular diseases and so on.
摘要翻译：公开了制备丹参酚酸的方法及其用途。该方法包括：用水提取丹参，用聚酰胺柱和大孔吸附树脂柱分离精制提取物，冻干得到丹参酚酸。最终产品的产率基于生药量大于4％，总酚酸含量大于80％。获得的丹参酚酸可用作预防和治疗脑血管和心血管疾病的药物等。

7. 发明申请

WO2006069114A3 PROCESS FOR PRODUCING GLYCOLIC ACID FROM FORMALDEHYDE AND HYDROGEN CYANIDE 审中-公开
标题翻译：由甲醛和氰化氰生产甘油酸的方法
公开(公告)号：WO2006069114A3
公开(公告)日：2006-10-12
申请号：PCT/US2005046273
申请日：2005-12-21
申请人： DU PONT , DICOSIMO ROBERT , FOO THOMAS , PAYNE MARK S , PANOVA ANNA , O'KEEFE DANIEL P , THOMPSON JEFFREY SCOTT , GALLAGHER F GLENN , LI XU
发明人： DICOSIMO ROBERT , FOO THOMAS , PAYNE MARK S , PANOVA ANNA , O'KEEFE DANIEL P , THOMPSON JEFFREY SCOTT , GALLAGHER F GLENN , LI XU
IPC分类号： C12P7/42 , C07C227/26
CPC分类号： C12P7/42
摘要： A process is provided for producing glycolic acid from formaldehyde and hydrogen cyanide. More specifically, heat-treated formaldehyde and hydrogen cyanide are reacted to produce glycolonitrile having low concentrations of impurities. The glycolonitrile is subsequently converted to an aqueous solution of ammonium glycolate using an enzyme catalyst having nitrilase activity derived from Acidovorax facilis 72W (ATCC 57746). Glycolic acid is recovered in the form of the acid or salt from the aqueous ammonium glycolate solution using a variety of methods described herein.
摘要翻译：提供了一种从甲醛和氰化氢生产乙醇酸的方法。更具体地说，热处理甲醛和氰化氢反应生成具有低浓度杂质的乙醇腈。随后使用衍生自敏捷食酸菌72W（ATCC 57746）的具有腈水解酶活性的酶催化剂将乙醇腈转化为乙醇酸铵的水溶液。使用本文所述的多种方法从羟基乙酸铵水溶液中以酸或盐的形式回收乙醇酸。

8. 发明申请

WO9926337A2 METHODS AND APPARATUS FOR AUTOMATICALLY SYNCHRONIZING AND REGULATING VOLUME IN AUDIO COMPONENT SYSTEMS 审中-公开
标题翻译：音频组件系统自动同步和调节音量的方法和装置
公开(公告)号：WO9926337A2
公开(公告)日：1999-05-27
申请号：PCT/US9824314
申请日：1998-11-13
申请人： MICROTEK LAB INC , LI XU , RUBIN ELLIOT M , SHOU XIAOFENG
发明人： LI XU , RUBIN ELLIOT M , SHOU XIAOFENG
IPC分类号： H03G5/16 , H03G
CPC分类号： H04S7/30 , H03G5/165 , H04S2400/13
摘要： A signal regulator regulates an auxiliary signal based upon a primary signal level scaled by an external amplifier. The signal regulator receives the primary signal with an unscaled level. Processing circuitry monitors the unscaled level of the primary signal. The primary signal is then output to the external amplifier for scaling, either by amplification or attenuation. The primary signal with a scaled level is in turn received by the signal regulator from the amplifier. The processing circuitry monitors the scaled level of the primary signal from the amplifier, and then generates a gain factor based upon the unscaled level and the scaled level of the primary signal. An auxiliary signal is received by the signal regulator. Adjusting circuitry receives the gain factor from the processing circuitry and adjusts a level of the auxiliary signal based upon the gain factor. The auxiliary signal with the adjusted level is then provided to an external component, for example, a loudspeaker. The signal regulator is particularly useful in regulating the volume of auxiliary audio channels in a surround-sound system based upon the volume of the main or front channels amplified by an audio/video receiver. The signal regulator performs system delay measurements, phase synchronization of the unscaled and scaled primary signals, volume tracking, and consecutive cross-correlation measurements to safeguard against erroneous volume adjustment.
摘要翻译：信号调节器根据由外部放大器缩放的初级信号电平来调节辅助信号。信号调节器接收到具有非等级电平的主信号。处理电路监控主信号的未标定电平。然后，通过放大或衰减将主信号输出到外部放大器进行缩放。具有缩放电平的主信号又由放大器的信号调节器接收。处理电路监视来自放大器的主信号的缩放电平，然后基于未平均电平和主信号的缩放电平产生增益因子。辅助信号由信号调节器接收。调整电路从处理电路接收增益因子，并根据增益因子调整辅助信号的电平。然后将具有调整电平的辅助信号提供给外部组件，例如扬声器。信号调节器基于由音频/视频接收器放大的主声道或前声道的音量来调节环绕声系统中的辅助音频通道的音量特别有用。信号调节器执行系统延迟测量，未缩放和缩放的初级信号的相位同步，体积跟踪和连续互相关测量，以防止错误的音量调节。

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