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    • 7. 发明申请
    • ORAL TREATMENT
    • 口腔治疗
    • WO1996015767A1
    • 1996-05-30
    • PCT/GB1995002683
    • 1995-11-15
    • UNILEVER PLCUNILEVER NV
    • UNILEVER PLCUNILEVER NVJOINER, AndrewKHOSHDEL, EzatPOLYWKA, Robert
    • A61K07/16
    • A61K8/898A61K8/8182A61K2800/57A61Q11/00
    • A method of treating an oral surface, particularly pellicle on the surface of teeth, with an oral treatment agent, comprising: (a) providing the oral treatment agent as molecules thereof having chemically bonded thereto at least one azlactone substituent moiety; (b) applying the azlactone-functionalised oral treatment agent to the oral substrate to effect reaction of the or each azlactone moiety with a or a respective nucleophilic reactive site (e.g. from a protein in the surface substrate layer) on the oral substrate; whereby the molecules of oral treatment agent are chemically bound to the oral substrate to impart their one or more cosmetic, pharmaceutical or therapeutic benefits thereto. The chemisorption resulting from the reaction of the azlactone group or groups with the oral substrate surface provides a significantly longer lasting oral benefit compared with conventional oral delivery systems. The novel azlactone-functionalised oral treatment agents, e.g. antistain agents, may be delivered from conventional compositions, e.g. toothpastes, mouthwashes, etc.
    • 一种用口腔治疗剂处理口腔表面,特别是牙齿表面上的防护薄膜组件的方法,包括:(a)提供口服处理剂作为其化学键合至少一个吖内酯取代基部分的分子; (b)将吖内酯官能化的口服治疗剂施用于口腔底物,以使口服底物上的每个吖内酯部分与相应的亲核反应位点(例如来自表面底物层中的蛋白质)发生反应; 由此口服治疗剂的分子与口腔基质化学结合以赋予其一种或多种化妆品,药​​物或治疗益处。 与常规口服递送系统相比,由吖内酯组或口服基质表面反应产生的化学吸附提供了显着更长的口服效果。 新的吖内酯官能化口服治疗剂,例如 抗静电剂,可以从常规组合物,例如, 牙膏,漱口水等
    • 9. 发明申请
    • GLASS AND CERAMIC CLEANING COMPOSITIONS
    • 玻璃和陶瓷清洁组合物
    • WO1996000274A1
    • 1996-01-04
    • PCT/EP1995001942
    • 1995-05-22
    • UNILEVER PLCUNILEVER NV
    • UNILEVER PLCUNILEVER NVSAMS, Philip, JohnSMITH, Gillian
    • C11D01/72
    • C11D3/3738C09K3/18C11D1/72C11D1/722
    • Silicone glycols of a particular molecular weight range are effective in preventing streaking of cleaning compositions which contain liquid, non-ionic surfactants, particularly on glass and ceramic surfaces. The invention provides a cleaning composition comprising: (a) 0.05-10 %wt of a liquid, alcohol alkoxylate, non-ionic surfactant, and (b) at least 5 % on total surfactant of a silicone glycol having a molecular weight in the range >3,000-40,000. It is believed that the synergistic interaction of the selected non-ionic surfactant and the selected silicone glycol polymer maintains a low surface tension in the drying film and prevents roll-up of droplets to form streaks. A second aspect of the invention provides a method of cleaning a glass or ceramic surface which comprises the step of treating the surface with a composition as described above.
    • 具有特定分子量范围的硅氧烷有效防止含有液体非离子表面活性剂,特别是玻璃和陶瓷表面的清洁组合物的条纹。 本发明提供一种清洁组合物,其包含:(a)0.05-10重量%的液体,醇烷氧基化物,非离子表面活性剂,和(b)至少5%的总表面活性剂的分子量在该范围内的硅氧烷二醇 > 3000-40000。 据信,所选择的非离子表面活性剂和所选择的硅氧烷二醇聚合物的协同相互作用在干燥膜中保持较低的表面张力,并防止液滴卷曲形成条纹。 本发明的第二方面提供一种清洁玻璃或陶瓷表面的方法,其包括用如上所述的组合物处理该表面的步骤。