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1. 发明申请

WO2017199215A1 SMART VALVED HOLDING CHAMBER 审中-公开
标题翻译：智能阀门保持室
公开(公告)号：WO2017199215A1
公开(公告)日：2017-11-23
申请号：PCT/IB2017/052968
申请日：2017-05-19
申请人： TRUDELL MEDICAL INTERNATIONAL
发明人： ALIZOTI, Neritan , COSTELLA, Stephen , ENGELBRETH, Dan , GULKA, Noel , KIRCHNER, Alanna , MEYER, Adam , MORTON, Robert , NOWAK, Bart , ROMANCZUK, Greg , SAKARIA, Ronak
IPC分类号： A61M15/00 , A61B5/08 , A61B90/00 , A61M99/00
摘要： A medication delivery system having a holding chamber capable of delivering dosages of medicament from a metered dose inhaler. The holding chamber includes an actuator detector, a flow detector and/or a metered dose inhaler identifier operable to identify the metered dose inhaler coupled to the holding chamber, and a display. In another embodiment, a user interface for administering a medication includes a medication delivery device, a mask portion having a sealing portion with a contact sensor responsive to contact being made with the user, and an indicator in communication with the sensor to provide feedback. In another embodiment, a medication delivery system includes a housing defining a flow channel, a valve disposed in the flow channel moveable between first and second configurations in response to a flow, and wherein the valve comprises an electroactive polymer and is reconfigurable between a first resistance condition and a second resistance condition in response to electrical stimuli.
摘要翻译：药物输送系统具有能够从定量吸入器输送药剂剂量的保持腔室。保持腔室包括致动器检测器，流量检测器和/或定量吸入器识别器，其可操作以识别联接到保持腔室的定量吸入器和显示器。在另一个实施例中，用于管理药物的用户界面包括药物输送装置，具有密封部分的面罩部分以及与所述传感器通信以响应与所述使用者接触的接触传感器的指示器，以提供反馈。在另一个实施例中，药物输送系统包括限定流动通道的壳体，设置在流动通道中的阀响应于流动而在第一和第二构造之间移动，并且其中阀包括电活性聚合物并且可在第一阻力条件和响应电刺激的第二阻力条件。

2. 发明申请

WO2018104805A1 SMART NEBULIZER 审中-公开
公开(公告)号：WO2018104805A1
公开(公告)日：2018-06-14
申请号：PCT/IB2017/055603
申请日：2017-09-15
申请人： TRUDELL MEDICAL INTERNATIONAL
发明人： COSTELLA, Stephen , DITTMER, Andrew , KILROY, Luke , KIRCHNER, Alanna , MORTON, Robert , SCHMIDT, James
IPC分类号： A61M11/00 , A61K9/72 , A61M15/00 , A61M99/00
摘要： A nebulizer system capable of identifying when activation has occurred and aerosol is being produced. The nebulizer system monitors the inhalation and exhalation flow generated by the patient and communicates proper breathing technique for optimal drug delivery. The nebulizer system may monitor air supply to the nebulizer to ensure it is within the working range and is producing, or is capable of producing, acceptable particle size and drug output rate. When a patient, caregiver or other user deposits or inserts medication into the nebulizer, the nebulizer system is able to identify the medication and determine the appropriate delivery methods required to properly administer the medication as well as output this information into a treatment log to ensure the patient is taking the proper medications. The system is able to measure the concentration of the medication and volume of the medication placed within the medication receptacle, e.g., bowl.

3. 发明申请

WO2009071986A2 SYSTEMS AND METHODS FOR EVALUATING MEDICATION DELIVERY FROM VALVED HOLDING CHAMBERS WITH A FACEMASK USING A MODEL FACE 审中-公开
标题翻译：使用模型表面评估使用FACEMASK的阀门进行药物输送评估的系统和方法
公开(公告)号：WO2009071986A2
公开(公告)日：2009-06-11
申请号：PCT/IB2008/003371
申请日：2008-12-05
申请人： TRUDELL MEDICAL INTERNATIONAL
发明人： LIMBRICK, Myles , MORTON, Robert , NAGEL, Mark , MITCHELL, Jolyon , GUBBELS, Peter , WIERSEMA, Kimberly , DOYLE, Cathy , AVVAKOUMOVA, Valentina
IPC分类号： G01M99/00
CPC分类号： A61M16/06 , A61M15/009 , A61M2016/0027 , A61M2016/003 , A61M2209/02 , A61M2209/084 , A61M2210/0606 , A62B27/00 , G09B23/32
摘要： Systems and methods for evaluating medication delivery from valved holding chambers (VHCs) with a facemask using a model face of a child or a model face of an infant are disclosed. Generally, the model face includes "a base, an elastomer cast, an air pocket, and a mouth opening. The elastomer cast is positioned on at least a portion of a top of the base. The elastomer simulates soft tissues in a face and defiens at least a nose, a chin, and a mouth sized to simulate a nose, a chin, and a mouth of a child. The air pocket is positioned between the base and the elastomer case below at least the nose, the chin, and the mouth of the elastomer cast. The mouth opening defines a passageway through the base, the air pocket, and the mouth of the elastomer cast.
摘要翻译：公开了使用儿童的模型面或婴儿的模型面评估带有面罩的带阀门的室内（VHC）的药物递送的系统和方法。通常，模型面包括“基底，弹性体铸件，气穴和开口”，弹性体铸件位于基体顶部的至少一部分上，弹性体模拟面部的软组织至少一个鼻子，一个下巴和一个口大小模拟鼻子，一个下巴和一个孩子的嘴巴，气囊位于底部和弹性体外壳之间，至少在鼻子，下巴和嘴部开口限定通过基座，气穴和弹性体口的通道。

4. 发明申请

WO2002096490A2 MEDICAMENT APPLICATOR 审中-公开
标题翻译：医学应用者
公开(公告)号：WO2002096490A2
公开(公告)日：2002-12-05
申请号：PCT/IB2002/001650
申请日：2002-05-14
申请人： TRUDELL MEDICAL INTERNATIONAL
发明人： ENGELBRETH, Daniel, K. , FOLEY, Martin, P. , GRYCHOWSKI, Jerry , MORTON, Robert
IPC分类号： A61M15/00
CPC分类号： G01F13/00 , A61M15/0068 , A61M15/0075 , A61M15/009 , A61M15/08 , B05B11/0037 , B05B11/3056 , B05B11/308 , B65D83/386
摘要： An actuator is used to dispense a medicament from a container having at least a first and second portion. The actuator includes a holder, a trigger member and a push member. The holder is adapted to engage at least the first portion of the container. The trigger member is pivotally connected to the holder at a pivot axis, wherein the trigger member is pivotable about the pivot axis in a first direction toward the grippable portion and a second direction opposite the first direction. The push member is connected to the trigger member, wherein the push member is pivotable about the pivot axis in the first direction as the trigger member is pivoted in the first direction and wherein the push member is pivotable about the pivot axis in the second direction as the trigger member is pivoted in the second direction. The push member is adapted to move at least the second portion of the container relative to the holder as the push member is pivoted in the first direction. In one preferred embodiment, the trigger member follows a path, and a stop member engages one of the container and push member and immobilizes the push member as the trigger is moved along a predetermined portion of the path. In one preferred embodiment, a trip member engages the stop member and disengages it from one of the container and the push member, thereby allowing the push member to move the second portion of the container. In one preferred embodiment, the actuator includes an indicator mechanism for indicating the number of doses remaining in or dispensed from the container. A method of dispensing medicament from the container, and a method of assembling the actuator also are provided. A nasal applicator is also provided, and includes a diffuser having a passageway comprising a tapered portion.
摘要翻译：致动器100用于从具有至少第一和第二部分的容器5分配药物。致动器包括保持器102，触发器构件120和推动构件430.保持器适于接合容器的至少第一部分。触发构件在枢转轴线156处枢转地连接到保持器，其中触发构件可绕第一方向围绕枢转轴线朝向可抓握部分枢转，而第二方向可绕第一方向枢转。推动构件连接到触发构件，其中当触发构件沿第一方向枢转时，推动构件可围绕枢转轴线在第一方向上枢转，并且其中推动构件可绕第二方向的枢转轴线枢转，如触发构件在第二方向上枢转。在一个优选实施例中，触发构件遵循路径，并且止动构件604接合容器和推动构件中的一个，并且在触发器沿着路径的预定部分移动时固定推动构件。在一个优选实施例中，跳闸构件608接合止动构件并将其从容器和推动构件中的一个脱离，从而允许推动构件移动容器的第二部分。在一个优选实施例中，致动器包括用于指示剩余在容器中或从容器分配的9个剂量的指示器机构500。提供了从容器分配药物的方法以及组装致动器的方法。还提供鼻施用器，并且包括具有包括锥形部分30的通道的扩散器20。

5. 发明申请

WO2018211474A1 POSITIVE EXPIRATORY PRESSURE DEVICE 审中-公开
公开(公告)号：WO2018211474A1
公开(公告)日：2018-11-22
申请号：PCT/IB2018/053527
申请日：2018-05-18
申请人： TRUDELL MEDICAL INTERNATIONAL
发明人： COSTELLA, Stephen , FOLEY, Martin , KIRCHNER, Alanna , MORTON, Robert , COLLINS, Jason , GRYCHOWSKI, Jerry
IPC分类号： A61M16/20 , A61M16/00 , A61M16/06
摘要： A positive exhalation pressure device to increase the pressure gradient in the airways through the use of a valve housing coupled to a mouthpiece and having a flow passageway communicating between the ambient environment and the oral cavity, and a valve disposed in the housing, wherein the valve is moveable between first and second positions during inhalation and exhalation respectively, wherein the flow passageway is more restricted during exhalation than during inhalation.

6. 发明申请

WO2018007997A1 SMART OSCILLATING POSITIVE EXPIRATORY PRESSURE DEVICE 审中-公开
标题翻译：智能振荡正压充气装置
公开(公告)号：WO2018007997A1
公开(公告)日：2018-01-11
申请号：PCT/IB2017/054123
申请日：2017-07-07
申请人： TRUDELL MEDICAL INTERNATIONAL
发明人： COSTELLA, Stephen , KIRCHNER, Alanna , MORTON, Robert , MEYER, Adam , SCARROTT, Peter
IPC分类号： A61M16/00 , A61B5/08 , A61B5/087
摘要： An oscillating positive expiratory pressure system including an oscillating positive expiratory pressure device having a chamber, an input component in communication with the chamber, wherein the input component is operative to sense a flow and/or pressure and generate an input signal correlated to the flow or pressure, a processor operative to receive the input signal from the input component and generate an output signal, and an output component operative to receive the output signal, and display an output.
摘要翻译：呼吸振动式压力系统包括具有腔室的振动式呼气正压装置，与腔室连通的输入部件，其中输入部件用于感测流量和/或压力并产生与流量或压力相关的输入信号，可操作以从输入部件接收输入信号并产生输出信号的处理器，以及可操作以接收输出信号并显示输出的输出部件。

7. 发明申请

WO2017093966A1 HUFF COUGH SIMULATION DEVICE 审中-公开
标题翻译： HUFF COUGH仿真设备
公开(公告)号：WO2017093966A1
公开(公告)日：2017-06-08
申请号：PCT/IB2016/057311
申请日：2016-12-02
申请人： TRUDELL MEDICAL INTERNATIONAL
发明人： COSTELLA, Stephen , MORTON, Robert , SCHMIDT, James
IPC分类号： A61M16/00 , A61H31/00 , A61M16/20
CPC分类号： A61M16/201 , A61M15/002 , A61M15/0021 , A61M15/0086 , A61M15/009 , A61M16/0006 , A61M16/0866 , A61M16/14 , A61M16/208 , A61M2202/064
摘要： A respiratory treatment device having an inlet configured to receive exhaled air into the device, an outlet configured to permit exhaled air to exit the device, a valve moveable in response to a threshold exhalation pressure at the inlet between a closed position where the flow of air from the inlet to the outlet is restricted, and an open exhalation position where the flow of air from the inlet to the outlet is less restricted, and a valve brace configured to support the valve, wherein a position of the valve brace relative to the valve is selectively adjustable to increase or decrease the threshold exhalation pressure.
摘要翻译：呼吸治疗装置具有构造成将呼出空气接收到装置中的入口，构造成允许呼出空气离开装置的出口，响应于入口处的入口处的阈值呼气压力可移动的阀其中从入口到出口的空气流动受到限制的闭合位置以及从入口到出口的空气流动受到较少限制的开放呼出位置以及被配置为支撑阀门的瓣膜支架，其中，位置阀门支架相对于阀门的压力可选择性地调节，以增加或减少阀值呼气压力。

8. 发明申请

WO2006077486A1 DISPENSING DEVICE 审中-公开
标题翻译：分配设备
公开(公告)号：WO2006077486A1
公开(公告)日：2006-07-27
申请号：PCT/IB2006/000084
申请日：2006-01-19
申请人： TRUDELL MEDICAL INTERNATIONAL
发明人： LU, Winston , MORTON, Robert , PICKARD, Mark , BALLES, Joaquim
IPC分类号： A61M15/00 , A61M11/00 , A61J1/00
CPC分类号： A61M15/0073 , A61M11/08 , A61M15/0021 , A61M15/0025 , A61M15/0065 , A61M15/0068 , A61M15/007 , A61M15/0076 , A61M15/008 , A61M15/009 , A61M16/0816 , A61M16/20 , A61M2039/268 , A61M2205/27 , Y10T29/49826
摘要： A dispenser includes a dispenser housing, an indicating device connected to the dispenser housing and a container removably engaged with the dispenser housing. A connector maintains a connection between the container and the dispenser housing as the container is moved between an engaged position and a disengaged position relative to the dispenser housing. In another aspect, a dispenser includes a dispenser housing, a key device adapted to be mounted to a container and an indicating device. The key device is moveable between an engaged position wherein it is engaged with the indicating device and a disengaged position wherein it is disengaged from the indicating device.
摘要翻译：分配器包括分配器壳体，连接到分配器壳体的指示装置和可拆卸地与分配器壳体接合的容器。当容器在接合位置和相对于分配器壳体的脱离位置之间移动时，连接器保持容器和分配器壳体之间的连接。在另一方面，分配器包括分配器壳体，适于安装到容器的关键装置和指示装置。关键装置可在其与指示装置接合的接合位置和脱离位置之间移动，其中它与指示装置脱离接合。

9. 发明申请

WO2005041850A1 INDICATING DEVICE WITH WARNING DOSAGE INDICATOR 审中-公开
标题翻译：用警告剂量指示剂指示装置
公开(公告)号：WO2005041850A1
公开(公告)日：2005-05-12
申请号：PCT/CA2004/001884
申请日：2004-10-28
申请人： TRUDELL MEDICAL INTERNATIONAL
发明人： MORTON, Robert , LU, Winston
IPC分类号： A61J7/00
CPC分类号： A61M15/0076 , A61M15/0065 , A61M15/0073 , A61M15/0075 , A61M15/009
摘要： An indicating device suitable for indicating the number of dosages of a substance that have been dispensed from or remain in a container includes at least one first indicator member incrementally moveable to a plurality of positions and a second indicator member moveable in response to a predetermined number of movements of the at least one first indicator member. The at least one first indicator member includes primary dosage indicia adapted to indicate the number of dosages of substance that have been dispensed from or remain in the container. The second indicator member includes secondary dosage indicia adapted to indicate that less than a minimum predetermined number of dosages of substance remain in the container. In one preferred embodiment, the primary dosage indicia are configured as numerical indicia and the secondary dosage indicia are configured as color indicia. In another aspect, a device for dispensing dosages of a substance includes a dispenser housing and a container disposed in the dispenser housing. The indicating device is located adjacent to and is actuated by one or the other of the top or bottom of the container. A method for indicating the number of metered dosages of medicaments dispensed from or remaining in the container is also provided.
摘要翻译：适于指示从容器中分配或保留在容器中的物质的剂量数量的指示装置包括至少一个第一指示器构件，其可递增地移动到多个位置，第二指示器构件可响应于预定数量的所述至少一个第一指示器构件的运动。所述至少一个第一指示器构件包括主要剂量标记，其适于指示已从或从容器分配的物质的剂量数。第二指示器构件包括适于指示小于预定数量的物质的物质残留在容器中的次级剂量标记。在一个优选的实施方案中，主要剂量标记被配置为数字标记，次级剂量标记被配置为颜色标记。在另一方面，用于分配物质的剂量的装置包括分配器壳体和设置在分配器壳体中的容器。指示装置位于容器的顶部或底部中的一个或另一个附近并被致动。还提供了一种用于指示从容器中分配或保留在容器中的计量剂量的计量剂量的方法。

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