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1. 发明申请

WO2003020339A2 FLUID ASSISTED MEDICAL DEVICES, FLUID DELIVERY SYSTEMS AND CONTROLLERS FOR SUCH DEVICES, AND METHODS 审中-公开
标题翻译：流体辅助医疗装置，流体输送系统和用于这些装置的控制器和方法
公开(公告)号：WO2003020339A2
公开(公告)日：2003-03-13
申请号：PCT/US2002/028267
申请日：2002-09-05
申请人： TISSUELINK MEDICAL, INC. , MCCLURKEN, Michael, E. , LIPSON, David , LUZZI, Robert , OYOLA, Arnold, E. , GREELEY, Roger, D. , CHARBONNEAU, Mark, T.
发明人： MCCLURKEN, Michael, E. , LIPSON, David , LUZZI, Robert , OYOLA, Arnold, E. , GREELEY, Roger, D. , CHARBONNEAU, Mark, T.
IPC分类号： A61M
CPC分类号： A61B18/1445 , A61B17/32 , A61B18/1206 , A61B18/14 , A61B18/1442 , A61B2018/00011 , A61B2018/00029 , A61B2018/00035 , A61B2018/00065 , A61B2018/00404 , A61B2018/00589 , A61B2018/00595 , A61B2018/00601 , A61B2018/0063 , A61B2018/00702 , A61B2018/00744 , A61B2018/00779 , A61B2018/00791 , A61B2018/00809 , A61B2018/00875 , A61B2018/126 , A61B2018/1412 , A61B2018/1417 , A61B2018/1422 , A61B2018/1455 , A61B2018/1861 , A61B2218/002
摘要： Medical devices, methods and systems for treating tissue are provided. An exemplary system comprises a fluid from a fluid from a fluid source at a fluid flow rate, a surgical device which provides power and the fluid to the tissue and a control mechanism which changes a fluid flow rate provided from the surgical device and changes a power level provided from the surgical device. The fluid flow rate changes between at least two-zero flow rates and the power level changes between at least two non-zero levels. An exemplary method comprises providing a fluid from a fluid source at a fluid flow rate, providing a surgical device which provides power and the fluid to the tissue, and changing the fluid flow rate of fluid provided from the surgical device with a change in power level provided from the surgical device.
摘要翻译：提供了用于治疗组织的医疗装置，方法和系统。示例性系统包括来自流体源的流体以流体流速的流体，向组织提供动力和流体的外科装置以及改变从手术装置提供的流体流速并改变功率的控制机构从手术器械提供的水平。流体流速在至少两个零流量之间变化，功率水平在至少两个非零水平之间变化。一种示例性方法包括以流体流速从流体源提供流体，提供将功能和流体提供给组织的手术装置，以及改变从手术装置提供的流体的流体流速，功率水平的变化由外科装置提供。

2. 发明申请

WO2003024349A1 FLUID-ASSISTED MEDICAL DEVICES, SYSTEMS AND METHODS 审中-公开
标题翻译：流体辅助医疗设备，系统和方法
公开(公告)号：WO2003024349A1
公开(公告)日：2003-03-27
申请号：PCT/US2002/028488
申请日：2002-09-05
申请人： TISSUELINK MEDICAL, INC. , MCCLURKEN, Michael, E. , LIPSON, David , LUZZI, Robert , OYOLA, Arnold, E. , WILSON, Jonathan, E. , MAURER, Christopher, W. , GREELEY, Roger, D.
发明人： MCCLURKEN, Michael, E. , LIPSON, David , LUZZI, Robert , OYOLA, Arnold, E. , WILSON, Jonathan, E. , MAURER, Christopher, W. , GREELEY, Roger, D.
IPC分类号： A61B18/18
CPC分类号： A61B18/148 , A61B17/32 , A61B18/1206 , A61B18/1442 , A61B2018/00011 , A61B2018/00029 , A61B2018/00035 , A61B2018/00065 , A61B2018/00404 , A61B2018/00589 , A61B2018/00595 , A61B2018/00601 , A61B2018/0063 , A61B2018/00702 , A61B2018/00744 , A61B2018/00779 , A61B2018/00791 , A61B2018/00809 , A61B2018/00875 , A61B2018/126 , A61B2018/1412 , A61B2018/1417 , A61B2018/1422 , A61B2018/1455 , A61B2018/1861 , A61B2218/002
摘要： Surgical devices, systems and methods for treating tissue are provided. Also provided are systems for treating tissue and methods of treating tissue. An exemplary surgical device comprises a handle (20a) having a proximal end and a distal end; a shaft extending distally beyond the distal end of the handle, the shaft having a proximal end and a distal end; an electrode tip (45), at least a portion of the electrode tip extending distally beyond the distal end of the shaft, the electrode tip extending distally beyond the distal end of the shaft comprising a spherical end surface portion (25) and a cylindrical side surface portion, the spherical end surface portion located distal to the cylindrical side surface portion and comprising at least a portion of the distal end surface of the surgical device; and a fluid passage directed to provide a fluid towards the cylindrical side portion of the electrode tip.
摘要翻译：提供了用于治疗组织的手术装置，系统和方法。还提供了用于治疗组织的系统和处理组织的方法。示例性手术装置包括具有近端和远端的手柄（20a）远离手柄远端延伸的轴，该轴具有近端和远端; 电极尖端（45），所述电极末端的至少一部分向远侧延伸超出所述轴的远端，所述电极末端向远侧延伸超过所述轴的远端，包括球形端面部分（25）和圆柱形侧面表面部分，所述球形端表面部分位于所述圆柱形侧表面部分的远侧并且包括所述外科装置的远端表面的至少一部分; 以及用于朝向电极末端的圆柱形侧部提供流体的流体通道。

3. 发明申请

WO2006057966A3 FLUID-ASSISTED ELECTROSURGICAL DEVICES, ELECTROSURGICAL UNIT WITH PUMP AND METHODS OF USE THEREOF 审中-公开
公开(公告)号：WO2006057966A3
公开(公告)日：2006-06-01
申请号：PCT/US2005/042174
申请日：2005-11-21
申请人： TISSUELINK MEDICAL, INC. , MCCLURKEN, Michael, E. , LUZZI, Robert
发明人： MCCLURKEN, Michael, E. , LUZZI, Robert
IPC分类号： A61B18/12 , A61B18/14
摘要： The invention provides an electrosurgical unit comprising a radio-frequency power source and a pump, with the throughput of fluid expelled by the pump controlled by the RF power level setting and fluid flow rate setting. The invention also provides various electrosurgical devices which may be used with the electrosurgical unit. In one embodiment, the electrosurgical device comprises a first electrode tip spaced next to a second electrode tip with a portion of the first electrode tip facing the second electrode tip and a portion of the second electrode tip facing the first electrode tip, the first electrode tip and the second electrode tip both having a spherical distal end, and a fluid outlet arrangement to expel fluid onto the electrode tips solely at locations remote from the electrode tip portions facing each other.

4. 发明申请

WO2009108893A3 BONE TREATMENT SYSTEMS AND METHODS 审中-公开
公开(公告)号：WO2009108893A3
公开(公告)日：2009-09-03
申请号：PCT/US2009/035549
申请日：2009-02-27
申请人： DFINE, INC. , TRUCKAI, Csaba , KOHM, Andrew , SHADDUCK, John, H. , LUZZI, Robert
发明人： TRUCKAI, Csaba , KOHM, Andrew , SHADDUCK, John, H. , LUZZI, Robert
IPC分类号： A61L24/04
摘要： The present disclosure relates to bone cement formulations that have an extended working time for use in vertebroplasty procedures and other osteoplasty procedures together with cement injectors that include energy delivery systems for on-demand control of cement viscosity and flow parameters. The bone cement formulations may include a liquid component having at least one monomer and a non-liquid component including polymer particles and benzoyl peroxide (BPO). The non-liquid component may be further configured to allow controlled exposure of the BPO to the liquid monomer so as to enable control of the viscosity of the bone cement composition.

5. 发明申请

WO2008097855A2 BONE TREATMENT SYSTEMS AND METHODS 审中-公开
标题翻译：骨治疗系统和方法
公开(公告)号：WO2008097855A2
公开(公告)日：2008-08-14
申请号：PCT/US2008/052821
申请日：2008-02-01
申请人： DEFINE, INC. , LUZZI, Robert , SHADDUCK, John, H. , TRUCKAI, Csaba
发明人： LUZZI, Robert , SHADDUCK, John, H. , TRUCKAI, Csaba
IPC分类号： A61L24/00 , A61L27/46 , A61L27/50 , A61K6/00
CPC分类号： A61L24/0084 , A61B17/8822 , A61B17/8836 , A61B2017/00026 , A61B2017/00088 , A61B2017/00101 , A61L24/02 , A61L24/06 , A61L27/16 , A61L27/46 , A61L27/50 , A61L2430/02 , C08L33/12
摘要： Bone cement formulations are provided that have an extended working time for use in vertebroplasty procedures and other osteoplasty procedures. In one embodiment, a settable bone cement includes a polymerizable composition with a powder component comprising an X-Ray contrast medium and a liquid component, wherein the setting time of the cement is at least about 25 minutes, at least about 30 minutes, at least about 35 minutes, and at least about 40 minutes.
摘要翻译：提供骨水泥配方，其具有用于椎体成形术和其它成骨术程序的延长的工作时间。在一个实施方案中，可固化骨粘固剂包括具有包含X射线造影剂和液体组分的粉末组分的可聚合组合物，其中水泥的凝固时间至少为约25分钟，至少约30分钟，至少约35分钟，至少约40分钟。

6. 发明申请

WO2006062916A2 BONE TREATMENT SYSTEMS AND METHODS 审中-公开
标题翻译：骨治疗系统和方法
公开(公告)号：WO2006062916A2
公开(公告)日：2006-06-15
申请号：PCT/US2005/043984
申请日：2005-12-06
申请人： DFINE, INC. , TRUCKAI, Csaba , SHADDUCK, John, H. , LUZZI, Robert
发明人： TRUCKAI, Csaba , SHADDUCK, John, H. , LUZZI, Robert
IPC分类号： A61F2/34
CPC分类号： A61B18/14 , A61B17/7095 , A61B17/7098 , A61B17/8811 , A61B17/8822 , A61B17/8836 , A61B2017/00022 , A61B2017/00026 , A61B2017/00084 , A61B2018/00565 , A61F2/44 , A61L27/50 , A61L2430/38
摘要： The present invention relates in certain embodiments to medical devices for treating osteoplasty procedures such as vertebral compression fractures. More particularly, embodiments of the invention relate to instruments and methods for controllably restoring vertebral body height by controlling the geometry of fill material introduced into cancellous bone. A system 100 utilizes Rf energy in combination a conductive bone fill material 120 for polymerizing the surface of the inflow plume 165 to control the geometry of the fill material 120 and the application of force caused by inflows of fill material 120. In another embodiment, the method of treating bone includes injecting a volume of fill material 120 into a bone and selectively modifying a viscosity of a selected portion of the bone fill material 120 to control the direction of flow of the fill material 120 within the bone 90. The method can also include controlling at least one flow parameter of the flow of bone fill material 120. A system 100 for treating bone using this method includes an introducer 110A, 110B for delivering fill material 120 into the bone 90 and an energy source 125A selectively coupleable to the fill material 120 to alter the viscosity of the fill material 120 as it flows out of the introducer 110A, 110B.
摘要翻译：本发明在某些实施例中涉及用于治疗诸如椎骨压缩性骨折之类的骨整形手术的医疗装置。更具体地说，本发明的实施例涉及通过控制引入松质骨的填充材料的几何形状来可控地恢复椎体高度的器械和方法。系统100利用Rf能量结合导电骨填充材料120来聚合流入羽流165的表面以控制填充材料120的几何形状和由填充材料120的流入引起的力的施加。在另一个实施例中，治疗骨的方法包括将一定体积的填充材料120注入到骨中并选择性地改变骨填充材料120的选定部分的粘度以控制填充材料120在骨90内的流动方向。该方法还可以包括控制骨填充材料120的流动的至少一个流动参数。用于使用该方法治疗骨骼的系统100包括用于将填充材料120输送到骨骼90中的导入器110A，110B以及可选择地与填充物耦合的能量源125A 材料120以在填充材料120流出导引器110A，110B时改变填充材料120的粘度。

7. 发明申请

WO2006062939A2 BONE TREATMENT SYSTEMS AND METHODS 审中-公开
标题翻译：骨治疗系统和方法
公开(公告)号：WO2006062939A2
公开(公告)日：2006-06-15
申请号：PCT/US2005/044055
申请日：2005-12-06
申请人： DFINE, INC. , TRUCKAI, Csaba , SHADDUCK, John, H. , LUZZI, Robert
发明人： TRUCKAI, Csaba , SHADDUCK, John, H. , LUZZI, Robert
IPC分类号： A61F2/38 , A61B18/00 , A61L24/02
CPC分类号： A61B18/14 , A61B17/7095 , A61B17/7098 , A61B17/8811 , A61B17/8822 , A61B17/8836 , A61B2017/00022 , A61B2017/00026 , A61B2017/00084 , A61B2018/00565 , A61F2/44 , A61L27/50 , A61L2430/38
摘要： The present invention relates in certain embodiments to medical devices for treating osteoplasty procedures such as vertebral compression fractures. More particularly, embodiments of the invention relate to instruments and methods for controllably restoring vertebral body height by controlling the geometry of fill material introduced into cancellous bone. A system 100 utilizes Rf energy in combination a conductive bone fill material 120 for polymerizing the surface of the inflow plume 165 to control the geometry of the fill material 120 and the application of force caused by inflows of fill material 120. In another embodiment, the method of treating bone includes injecting a volume of fill material 120 into a bone and selectively modifying a viscosity of a selected portion of the bone fill material 120 to control the direction of flow of the fill material 120 within the bone 90. The method can also include controlling at least one flow parameter of the flow of bone fill material 120. A system 100 for treating bone using this method includes an introducer 110A, 110B for delivering fill material 120 into the bone 90 and an energy source 125A selectively coupleable to the fill material 120 to alter the viscosity of the fill material 120 as it flows out of the introducer 110A, 110B.
摘要翻译：本发明在某些实施例中涉及用于治疗诸如椎体压缩性骨折的骨整形术程序的医疗装置。更具体地，本发明的实施例涉及通过控制引入松质骨的填充材料的几何形状来可控地恢复椎体高度的仪器和方法。系统100组合使用导电骨填充材料120的Rf能量，用于聚合流入羽流165的表面以控制填充材料120的几何形状以及由填充材料120的流入引起的力的施加。在另一个实施例中，治疗骨的方法包括将一定体积的填充材料120注入骨中并选择性地改变骨填充材料120的选定部分的粘度以控制填充材料120在骨90内的流动方向。该方法还可以包括控制骨填充材料流120的至少一个流动参数。用于使用该方法处理骨的系统100包括用于将填充材料120输送到骨90中的导引器110A，110B和能够选择性地连接到填充物的能量源125A 材料120，以改变填充材料120流出导引器110A，110B时的粘度。

8. 发明申请

WO2008137428A2 BONE TREATMENT SYSTEMS AND METHODS 审中-公开
标题翻译：骨治疗系统和方法
公开(公告)号：WO2008137428A2
公开(公告)日：2008-11-13
申请号：PCT/US2008/061911
申请日：2008-04-29
申请人： DFINE, INC. , TRUCKAI, Csaba , SHADDUCK, John, H. , LUZZI, Robert
发明人： TRUCKAI, Csaba , SHADDUCK, John, H. , LUZZI, Robert
IPC分类号： A61F2/46 , A61L24/00
CPC分类号： A61B17/8822 , A61B17/88 , A61B17/8805 , A61B17/8811 , A61B17/8816 , A61B17/8836
摘要： The present invention relates in certain embodiments to systems and methods for treating bone, such as vertebral compression fractures. In one embodiment, a method includes controllably applying energy from an energy source to a bone cement volume outside of a patient's body to selectively accelerate the polymerization rate of the bone fill material volume prior to introduction of the bone fill material into a bone. The method further includes sequentially introducing a plurality of cement carrying structures with said accelerated polymerization rate bone cement volume into the bone. A system for use in said method includes at least one elongated cement-carrying structure sized to carry a bone cement volume therein and an energy source operatively coupleable to the cement- carrying structure. The energy source applies energy to the bone cement volume to selectively accelerate a polymerization rate thereof. An elongated injector is insertable into the bone and has a passageway that removably receives the elongated cement- carrying structure to allow delivery of the accelerated polymerization rate bone cement into the bone.
摘要翻译：本发明在某些实施方案中涉及用于治疗骨的系统和方法，例如椎体压缩性骨折。在一个实施例中，一种方法包括将能量源可控地施加到患者身体外部的骨水泥体积，以在将骨填充材料引入骨骼之前选择性地加速骨填充材料体积的聚合速率。该方法还包括将具有所述加速聚合速率骨水泥体积的多个水泥承载结构顺序地引入骨中。用于所述方法的系统包括尺寸适于承载骨水泥体积的至少一个细长的水泥承载结构，以及可操作地连接到承载结构的能量源。能量源将能量施加到骨水泥体积以选择性地加速其聚合速率。细长的注射器可插入到骨中，并且具有可移除地容纳细长的水泥承载结构以允许将加速的聚合速率骨水泥输送到骨中的通道。

9. 发明申请

WO2008124533A1 BONE TREATMENT SYSTEMS AND METHODS 审中-公开
标题翻译：骨治疗系统和方法
公开(公告)号：WO2008124533A1
公开(公告)日：2008-10-16
申请号：PCT/US2008/059305
申请日：2008-04-03
申请人： DFINE, INC. , TRUCKAI, Csaba , LUZZI, Robert , SHADDUCK, John, H.
发明人： TRUCKAI, Csaba , LUZZI, Robert , SHADDUCK, John, H.
IPC分类号： A61B17/58 , A61B18/04
CPC分类号： A61B17/8836 , A61B17/8822 , A61B2017/00022
摘要： Systems and methods for delivering bone cement into a bone can include a handle body defining a flow path, a thermal emitter in the handle body to apply energy to bone cement passing through the flow path, a source of bone cement and an injection cannula. The cannula can be in communication with the flow path such that inserting the cannula into a bone can allow a flow of bone cement therethrough to an opening at a distal end of the cannula. Other systems and methods for delivering bone cement into a bone can include an injector body with a handle portion, and a cannula, a bone cement container, a low pressure drive mechanism configured to effect a flow of bone cement from said container to the injector body and a high pressure drive mechanism configured to effect a flow of bone cement through the injector body into the bone.
摘要翻译：用于将骨水泥输送到骨中的系统和方法可以包括限定流路的手柄主体，手柄主体中的热发射器，以将能量施加到通过流路的骨水泥，骨水泥源和注射套管。套管可以与流动路径连通，使得将套管插入骨头可以允许骨水泥通过其穿过套管远端的开口。用于将骨水泥输送到骨头中的其它系统和方法可以包括具有手柄部分的注射器主体和套管，骨水泥容器，低压驱动机构，其被配置为实现骨粘固剂从所述容器流到喷射器主体以及高压驱动机构，其构造成使得骨水泥通过所述注射器主体流入所述骨中。

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