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    • 2. 发明申请
    • ELECTROSPRAY EMITTERS FOR MASS SPECTROMETRY
    • 用于大量光谱的电喷发射体
    • WO2011075449A1
    • 2011-06-23
    • PCT/US2010/060146
    • 2010-12-13
    • THERMO FINNIGAN LLCKOVTOUN, Viatcheslav V.WOUTERS, Eloy R.ATHERTON, R., Paul
    • KOVTOUN, Viatcheslav V.WOUTERS, Eloy R.ATHERTON, R., Paul
    • H01J49/16H01J49/06
    • H01J49/167H01J49/068
    • An electrospray ion source that comprises (a) an emitter capillary having (i) an internal bore for transporting a liquid sample, (ii) an electrode portion for providing a first applied electrical potential and (iii) an emitter tip for emitting charged particles generated from the liquid sample and (b) a counter electrode for providing a second applied electrical potential different from the first applied electrical potential is characterized by (c) a shield electrode disposed at least partially between the counter electrode and the emitter tip of the emitter capillary for providing a third applied electrical potential intermediate to the first and second applied electrical potentials, the shield electrode contoured in the form of a portion of an electrical equipotential surface formed, in the absence of the shield electrode, under application of the first and second applied electrical potentials to the electrode portion of the emitter capillary and to the counter electrode, respectively.
    • 一种电喷射离子源,包括(a)发射体毛细管,其具有(i)用于输送液体样品的内孔,(ii)用于提供第一施加电位的电极部分,和(iii)用于发射产生的带电粒子的发射极尖端 (b)用于提供不同于第一施加电位的第二施加电位的对电极的特征在于(c)至少部分地设置在对电极和发射极毛细管的发射极尖端之间的屏蔽电极 为了向第一和第二施加的电势提供第三施加的电势中间体,在不存在屏蔽电极的情况下形成的电等电位表面的一部分形式的屏蔽电极在施加第一和第二施加的电势 发射极毛细管和对电极的电极部分的电位分别为1 年。
    • 3. 发明申请
    • SYSTEM FOR PREVENTING BACKFLOW IN AN ION SOURCE
    • 用于在离子源中防止回流的系统
    • WO2011037942A1
    • 2011-03-31
    • PCT/US2010/049725
    • 2010-09-21
    • THERMO FINNIGAN LLCWOUTERS, Eloy, R.MULLEN, ChristopherSPLENDORE, MaurizioATHERTON, R., Paul
    • WOUTERS, Eloy, R.MULLEN, ChristopherSPLENDORE, MaurizioATHERTON, R., Paul
    • B01D59/44
    • H01J49/0445
    • A system for preventing backflow as part of an ion source arrangement is introduced. Such a system incorporates a novel continuous flow guide within a source, such as an API ion source. In the spray direction, the cross-sectional area that defines the first portion of the internal volume initially decreases in a convergent-like manner and thereafter increases in a divergent-like manner towards the exit opening of the source housing. Such a flow guide has been designed as an integral part of an ion source housing to provide for an optimal unidirectional flow past a sampling orifice of a mass spectrometer inlet. Accordingly, the novel design of the present invention prevents recirculation and thus minimizes carryover, chemical noise, and source turbulence and as an added benefit, enables a user to easily clean such a system during maintenance.
    • 引入了用于防止作为离子源装置的一部分的回流的系统。 这样的系统在源内包含新颖的连续流动引导件,例如API离子源。 在喷射方向上,限定内部容积的第一部分的横截面面积首先以收敛方式减小,然后以发散方式朝向源壳体的出口开口增加。 这种流动引导件已被设计为离子源壳体的组成部分,以提供通过质谱仪入口的采样孔的最佳单向流动。 因此,本发明的新颖设计防止再循环,从而使携带,化学噪声和源湍流最小化,并且作为附加的益处,使得用户能够在维护期间容易地清洁这样的系统。