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1. 发明申请

WO2008127730A1 INJECTIBLE CYANOACRYLATE-FUNCTIONALIZED POLYISOBUTYLENES 审中-公开
标题翻译：可注射的氰基丙烯酸酯官能化聚异丁烯
公开(公告)号：WO2008127730A1
公开(公告)日：2008-10-23
申请号：PCT/US2008/004870
申请日：2008-04-14
申请人： THE UNIVERSITY OF AKRON , KENNEDY, Joseph, P. , KWON, Yongmoon , JEWRAJKA, Suresh
发明人： KENNEDY, Joseph, P. , KWON, Yongmoon , JEWRAJKA, Suresh
IPC分类号： A61F2/00 , A61F2/16 , C10M169/00
CPC分类号： C10M107/42 , A61L27/16 , A61L2400/06 , C10M2205/0265 , C10M2217/026 , C10M2217/0265 , C10N2220/021 , C10N2260/09 , C08L23/20 , C08L101/02
摘要： The present invention generally relates to injectible polyisobutylene polymer compounds. More specifically, the present invention relates to injectible polyisobutylene polymer compounds that are designed for various biological and medical applications. In one embodiment, the present invention relates to injectible functionalized polyisobutylene polymer compounds that are designed for various biological and medical applications. In another embodiment, the present invention relates to injectible cyanoacrylate-functionalized polyisobutylene polymer compounds.
摘要翻译：本发明一般涉及可注射聚异丁烯聚合物化合物。更具体地说，本发明涉及为各种生物和医学应用设计的可注射聚异丁烯聚合物化合物。在一个实施方案中，本发明涉及被设计用于各种生物和医学应用的可注射官能化聚异丁烯聚合物化合物。在另一个实施方案中，本发明涉及可注射的氰基丙烯酸酯官能化的聚异丁烯聚合物化合物。

2. 发明申请

WO1998005701A1 MULTI-ARM STAR POLYMERS HAVING A WELL-DEFINED CORE AND METHODS FOR THE SYNTHESIS THEREOF 审中-公开
标题翻译：具有良好定义核心的多臂星形聚合物及其合成方法
公开(公告)号：WO1998005701A1
公开(公告)日：1998-02-12
申请号：PCT/US1997014016
申请日：1997-08-07
申请人： THE UNIVERSITY OF AKRON
发明人： THE UNIVERSITY OF AKRON , KENNEDY, Joseph, P. , MAJOROS, Istvan, J. , MARSALKO, Timea, M.
IPC分类号： C08G77/38
CPC分类号： C07C43/215 , C07C69/712 , C07C2603/92 , C08G77/38 , C08G77/52 , C08G81/024
摘要： The synthesis of star polymers having well-defined arms emanating from well-defined and readily controllable calix[n]arene (n=4 to 16) cores are described. The synthesis is particularly suitable for polyisobutylene and/or polysiloxane star polymers. The synthesis has been achieved using carbocationic and/or anionic ring opening polymerization techniques to form polymer arms of desired molecular weights, then separately preparing the calixarene derivative core, and finally, linking the arms to the core by transesterification or hydrosilation. The star polymers are usable as viscosity modifiers and oil additives since they are less sensitive to oxidative reactions and shear stable.
摘要翻译：描述了从明确定义且容易控制的杯[n]芳烃（n = 4至16）核发出具有明确定义的臂的星形聚合物的合成。该合成特别适用于聚异丁烯和/或聚硅氧烷星形聚合物。已经使用碳阳离子和/或阴离子开环聚合技术来合成以形成所需分子量的聚合物臂，然后分别制备杯芳烃衍生物核心，最后通过酯交换或硅氢化将臂连接到核心。星形聚合物可用作粘度调节剂和油添加剂，因为它们对氧化反应和剪切稳定性较不敏感。

3. 发明申请

WO1993016120A1 LIVING CARBOCATIONIC POLYMERIZATION OF POLY(ISOBUTYLENE-b_-METHYL VINYL ETHER) 审中-公开
标题翻译：聚异丁烯（异丁基 - 乙基乙基乙烯基醚）的生物聚合聚合
公开(公告)号：WO1993016120A1
公开(公告)日：1993-08-19
申请号：PCT/US1993000203
申请日：1993-01-11
申请人： THE UNIVERSITY OF AKRON
发明人： THE UNIVERSITY OF AKRON , KENNEDY, Joseph, P. , PERNECKER, Tibor , IVAN, Bela
IPC分类号： C08F297/02
CPC分类号： C08F297/00
摘要： The synthesis of poly(isobutylene-b^_-methyl vinyl ether) (PIB-b^_-PMeVE) by living carbocationic polymerization (LC+Pzn) employing the sequential monomer addition (SMA) technique is described. The process starts by producing the living PIB+ block employing the 2-chloro-2,4,4-trimethylpentane (TMPCll/TiCl¿4?) initiating system in the presence of the common ion salt tetra-n-butylammonium chloride (n-Bu4NCl) in CH3Cl/n-C6H14 or CH2Cl2/n-C6H14 mixed solvents at -80 °C and continues by the addition of methyl vinyl ether (MeVE). The second living block forms only in the presence of excess TiCl4 suggesting that the species that starts the second block and subsequently sustains its growth is an MeVE.TiCl4 complex. The stoichiometry of this complex (1:1 or 1:2) is uncertain. The TiCl4 remains attached to the MeVE units after their incorporation into the diblock, however, it can be readily removed by water. PMeVE obtained in the presence of excess TiCl4 degrades by dealcoholation, however, degradation is prevented by the use of n-Bu4NCl. Various length (composition) diblocks have been prepared and characterized. The novel PIB-b^_-PMeVE's exhibit strongly amphiphilic character.

4. 发明申请

WO2007079240A2 PHOTOCURABLE POLYMERS FOR OPHTHALMIC APPLICATIONS 审中-公开
标题翻译：用于眼科应用的可光固化聚合物
公开(公告)号：WO2007079240A2
公开(公告)日：2007-07-12
申请号：PCT/US2006/049611
申请日：2006-12-29
申请人： THE UNIVERSITY OF AKRON , KENNEDY, Joseph, P. , CHEN, Yaohong
发明人： KENNEDY, Joseph, P. , CHEN, Yaohong
IPC分类号： C08G77/42
CPC分类号： C08G77/50 , C07F7/0852 , C08G77/045 , C08G77/14 , C08G77/46 , G02B1/043 , C08L83/06
摘要： The present invention generally relates to pre-polymer and polymer compositions that can be photopolymerized. In one embodiment, the present invention relates to crosslinking agents that can be used in the photopolymerization of the pre-polymers and polymers disclosed herein. In another embodiment, the present invention relates to processes for producing pre-polymer, polymer and crosslinking compositions useful in photopolymerization reaction schemes. In one instance, the pre-polymers and polymers of the present invention can be crosslinked via a suitable crosslinking agent to produce networks (e.g., amphiphilic networks and/or co-networks).
摘要翻译：本发明一般涉及可以光聚合的预聚物和聚合物组合物。在一个实施方案中，本发明涉及可用于本文公开的预聚物和聚合物的光聚合的交联剂。在另一个实施方案中，本发明涉及用于制备用于光聚合反应方案的预聚物，聚合物和交联组合物的方法。在一种情况下，本发明的预聚物和聚合物可以通过合适的交联剂交联以产生网络（例如，两亲网络和/或共网络）。

5. 发明申请

WO2005003195A1 THERMOPLASTIC ELASTOMERIC MULTIBLOCK COPOLYMERS OF ISOBUTYLENE AND NORBORNENE 审中-公开
标题翻译：异丁烯和异丁烯的热塑性弹性体多元共聚物
公开(公告)号：WO2005003195A1
公开(公告)日：2005-01-13
申请号：PCT/US2004/021320
申请日：2004-07-01
申请人： THE UNIVERSITY OF AKRON , KENNEDY, Joseph, P. , PEETZ, Ralf, M.
发明人： KENNEDY, Joseph, P. , PEETZ, Ralf, M.
IPC分类号： C08F110/10
CPC分类号： C09J153/00 , C08F210/10 , C08F297/00 , C08L53/00 , C08L2666/02 , C08L2666/24 , C09D153/00 , C08F4/06
摘要： A composition of matter including a polyisobutylene segment and a polycycloolefin segment. The polyisobutylene segment and the polycycloolefin segment form a repeating unit multiblock copolymer. A method of forming a composition of matter that includes a polyisobutylene segment and a polycycloolefin segment.
摘要翻译：包括聚异丁烯链段和聚环烯烃链段的物质组合物。聚异丁烯链段和聚环烯烃链段形成重复单元多嵌段共聚物。一种形成包含聚异丁烯链段和聚环烯烃链段的物质组合物的方法。

6. 发明申请

WO1997034944A1 STAR POLYMERS HAVING A WELL-DEFINED SILOXANE CORE AND POLYISOBUTYLENE ARMS AND SYNTHESIS METHOD 审中-公开
标题翻译：具有良好定义的硅氧烷核心和聚异丁烯聚合物的星形聚合物和合成方法
公开(公告)号：WO1997034944A1
公开(公告)日：1997-09-25
申请号：PCT/US1997004667
申请日：1997-03-21
申请人： THE UNIVERSITY OF AKRON
发明人： THE UNIVERSITY OF AKRON , KENNEDY, Joseph, P. , OMURA, Naoki , LUBNIN, Alexander
IPC分类号： C08G77/12
CPC分类号： C08G81/024 , C08G77/442
摘要： The synthesis and characterization of novel multi-arm star polymers comprising polyisobutylene arms connected to a well-defined siloxane core are described. The synthesis has been achieved by hydrosilating olefin-capped (e.g., allyl- or isopropenyl-terminated) polyisobutylene with siloxanes carrying a plurality of Si-H groups.

7. 发明申请

WO2010039986A1 POLYMERS HAVING BOTH HARD AND SOFT SEGMENTS, AND PROCESS FOR MAKING SAME 审中-公开
标题翻译：具有两个硬和软部分的聚合物及其制备方法
公开(公告)号：WO2010039986A1
公开(公告)日：2010-04-08
申请号：PCT/US2009/059269
申请日：2009-10-01
申请人： THE UNIVERSITY OF AKRON , KENNEDY, Joseph, P. , ERDODI, Gabor , JEWRAJKA, Suresh , KANG, Jungmee
发明人： KENNEDY, Joseph, P. , ERDODI, Gabor , JEWRAJKA, Suresh
IPC分类号： C08F255/10
CPC分类号： C08G18/6204 , C08G18/10 , C08G18/758 , C08G18/3228
摘要： The present invention generally relates to alcohol- and amine-terminated polyisobutylene (PIB) compounds, and to a process for making such compounds. In one embodiment, the present invention relates to primary alcohol- and amine-terminated polyisobutylene compounds, and to a process for making such compounds. In still another embodiment, the present invention relates to polyisobutylene compounds that can be used to synthesize polyurethanes and polyureas, to polyurethane and polyurea compounds made via the use of such polyisobutylene compounds, and to processes for making such compounds. In yet another embodiment, the present invention relates to polyisobutylene compounds containing urea or urethane segments therein, and to a method of producing such compounds. In still yet another embodiment, the present invention relates to a polymer having one or more different soft segments and one or more different hard segments.
摘要翻译：本发明一般涉及醇和胺封端的聚异丁烯（PIB）化合物，以及制备这些化合物的方法。在一个实施方案中，本发明涉及伯醇和胺封端的聚异丁烯化合物，以及制备这些化合物的方法。在另一个实施方案中，本发明涉及可用于合成聚氨酯和聚脲的聚异丁烯化合物，通过使用这种聚异丁烯化合物制备的聚氨酯和聚脲化合物以及制备这些化合物的方法。在另一个实施方案中，本发明涉及其中含有脲或氨基甲酸酯链段的聚异丁烯化合物及其制备方法。在又一个实施方案中，本发明涉及具有一个或多个不同软链段和一个或多个不同硬链段的聚合物。

8. 发明申请

WO2009058397A1 THERMOPLASTIC AMPHIPHILIC CO-NETWORKS 审中-公开
标题翻译：热塑性共聚物网络
公开(公告)号：WO2009058397A1
公开(公告)日：2009-05-07
申请号：PCT/US2008/012436
申请日：2008-11-03
申请人： THE UNIVERSITY OF AKRON , KENNEDY, Joseph, P. , ERDODI, Gabor , KANG, Jungmee
发明人： KENNEDY, Joseph, P. , ERDODI, Gabor , KANG, Jungmee
IPC分类号： C08F265/00
CPC分类号： C08F265/00 , C08G77/442 , C08G77/458 , C08L51/085 , C08L83/10 , C08L2205/02 , C08L2666/24
摘要： The present invention relates generally to thermoplastic amphiphilic networks and/or co-networks. In one embodiment, the present invention relates to thermoplastic (TP) amphiphilic co-networks (APCNs) and the preparation of membranes from such APCNs. In another embodiment, the present invention relates to an amphiphilic network comprising at least one hydrophilic polymer-derived portion, at least one hydrophobic polymer-derived portion and at least one thermoplastic polymer-derived portion. In still another embodiment, the present invention relates to thermoplastic amphiphilic co-networks prepared by combining the chemistries of APCNs and polyurethanes (PUs) and to the preparation of membranes therefrom.
摘要翻译：本发明一般涉及热塑性两亲性网络和/或共同网络。在一个实施方案中，本发明涉及热塑性（TP）两亲性共同网络（APCN）和来自这种APCN的膜的制备。在另一个实施方案中，本发明涉及包含至少一种亲水性聚合物衍生部分，至少一种疏水性聚合物衍生部分和至少一种热塑性聚合物衍生部分的两亲网络。在另一个实施方案中，本发明涉及通过将APCN和聚氨酯（PU）的化学物质组合并由其制备的膜制备的热塑性两亲性共网络。

9. 发明申请

WO2008112190A1 BIO-ARTIFICIAL PANCREAS AND A PROCEDURE FOR PREPARATION OF SAME 审中-公开
标题翻译：生物人造胰腺及其制备方法
公开(公告)号：WO2008112190A1
公开(公告)日：2008-09-18
申请号：PCT/US2008/003146
申请日：2008-03-10
申请人： THE UNIVERSITY OF AKRON , KENNEDY, Joseph, P. , ERDODI, Gabor , CAKMAK, Mukerrem , YALCIN, Baris
发明人： KENNEDY, Joseph, P. , ERDODI, Gabor , CAKMAK, Mukerrem , YALCIN, Baris
IPC分类号： A61F2/04 , A61K9/22 , A61M31/00
CPC分类号： A61K9/0024 , A61F2/022
摘要： The present invention generally relates to implantable devices for producing insulin in diabetic animals and to methods of making same. Some embodiments include amphiphilic biomembranes for use in biological applications (e.g., as an alternative and/or supplemental insulin source). Some embodiments also include live insulin-producing cells contained within one or more amphiphilic membranes so as to prevent or diminish an immuno-response and/or rejection by the host.
摘要翻译：本发明一般涉及用于在糖尿病动物中产生胰岛素的可植入装置及其制备方法。一些实施方案包括用于生物应用的两亲生物膜（例如，作为替代和/或补充的胰岛素源）。一些实施方案还包括含在一个或多个两亲膜内的活的产生胰岛素的细胞，以便防止或减少宿主的免疫应答和/或排斥。

10. 发明申请

WO1998005691A1 STAR POLYMERS HAVING MULTIPLE POLYISOBUTYLENE ARMS EMANATING FROMA CALIXARENE CORE AND THE SYNTHESIS THEREOF 审中-公开
标题翻译：具有多巴胺聚核的多聚异戊二烯聚合物的STAR聚合物及其合成
公开(公告)号：WO1998005691A1
公开(公告)日：1998-02-12
申请号：PCT/US1997014017
申请日：1997-08-07
申请人： THE UNIVERSITY OF AKRON
发明人： THE UNIVERSITY OF AKRON , KENNEDY, Joseph, P. , MAJOROS, Istvan, J. , JACOB, Sunny
IPC分类号： C08F04/14
CPC分类号： C08F297/00 , C08F10/10 , C08F297/06 , C08F4/005 , C08F4/14
摘要： The synthesis and characterization of novel linear polymers and multi-arm star polymers comprising polyisobutylene arms connected to a well-defined calixarene core are described. The synthesis has been achieved using the "core first" method wherein multifunctional calix[n]arene (where n=4 to 16) derivatives or their monofunctional analogues are used as initiators which, in conjunction with certain Freidel-Crafts acids as co-initiators, induce the living polymerization of isobutylene or a similar carbocationic polymerizable monomer to form star polymers or block copolymers. Novel initiators suitable for inducing the polymerization are also described.
摘要翻译：描述了包含连接到明确定义的杯芳烃核心的聚异丁烯臂的新型线性聚合物和多臂星形聚合物的合成和表征。使用其中多功能杯[n]芳烃（其中n = 4至16）衍生物或其单官能类似物用作引发剂的“核心优先”方法已经实现了合成，其结合某些Freidel-Crafts酸作为共引发剂诱导异丁烯或类似的碳阳离子聚合单体的活性聚合形成星形聚合物或嵌段共聚物。还描述了适合于引发聚合的新型引发剂。

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