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    • 3. 发明申请
    • NANOMATERIALS FABRICATED USING SPARK EROSION AND OTHER PARTICLE FABRICATION PROCESSES
    • 使用火花腐蚀和其他颗粒制造工艺制成的纳米材料
    • WO2013056185A1
    • 2013-04-18
    • PCT/US2012/060141
    • 2012-10-12
    • THE REGENTS OF THE UNIVERSITY OF CALIFORNIAJIN, SunghoBERKOWITZ, Ami
    • JIN, SunghoBERKOWITZ, Ami
    • B82B3/00B82B1/00
    • B23H1/08B23H1/04B23H7/12B23H9/001
    • Methods, systems, and devices are disclosed for fabricating clean, oxidation-free nanoparticles of electrically conducting metals and alloys using spark erosion techniques. In one aspect, a method includes dispersing bulk pieces of an electrically conducting material in a dielectric fluid with mechanical vibrations within a container; generating an electric field using electrodes in the dielectric fluid using by an electric pulse, in which the electric field creates a plasma in a volume existing between the bulk pieces that locally heats the bulk pieces to form structures within the volume, the dielectric fluid quenching the structures to form nanoparticles, and filtering the nanoparticles through a screen including holes of a size allowing nanoparticles of the size or smaller to pass through the screen to a region in the container, in which the dielectric fluid inhibits oxidation of the surface of the nanoparticles.
    • 公开了用于使用火花腐蚀技术制造导电金属和合金的清洁,无氧化纳米颗粒的方法,系统和装置。 在一个方面,一种方法包括将散布的导电材料块分散在具有容器内的机械振动的电介质流体中; 使用电脉冲在电介质流体中产生使用电极的电场,其中电场产生存在于块体之间的体积中的等离子体,其局部加热块体以在体积内形成结构,介电流体淬灭 结构以形成纳米颗粒,并通过筛网过滤纳米颗粒,该筛网包括尺寸允许尺寸或更小尺寸的纳米颗粒的孔通过筛网到容器中的区域,其中介电流体抑制纳米颗粒表面的氧化。
    • 6. 发明申请
    • SWITCHABLE DIGITAL SCENT GENERATION AND RELEASE, AND VAPOR AND LIQUID DELIVERY METHODS AND SYSTEMS
    • 可切换的数字数据生成和发布,以及蒸气和液体输送方法和系统
    • WO2016164917A1
    • 2016-10-13
    • PCT/US2016/026971
    • 2016-04-11
    • THE REGENTS OF THE UNIVERSITY OF CALIFORNIASENSABLE TECHNOLOGIES LLC
    • JIN, SunghoGARDNER, CalvinMATTHEW, Stewart
    • B05B12/14
    • A61L9/035A61L9/037A61L9/125A61L9/127A61L9/14A61L2209/111A61L2209/132A61L2209/133A61L2209/135A61L2209/14
    • Methods, devices and systems are described for digitally creating new scents or digitally dispensing gas, vapor, or liquid substances. A device includes a container or replaceable cartridge including one or more chambers containing one or more scented substances; a housing structured to include a compartment to hold the cartridge, an opening to allow the one or more scented or unscented substances to dispense to an outer environment from the device, and one or more transporting channels formed between the compartment and the opening, in which each of the one or more transporting channels is configured to deliver a scented substance from the corresponding chamber to the opening for delivering a scent from the one or more scented substances; and an actuator switch arranged in a corresponding transporting channel and rapidly operable to move between an open position and closed position based on an applied signal to selectively allow passage of the scented or unscented substance from the corresponding transporting path.
    • 描述了用于数字创建新香水或数字分配气体,蒸汽或液体物质的方法,装置和系统。 一种装置包括容器或可替换的盒,其包括一个或多个容纳一种或多种香味物质的室; 壳体,构造成包括用于保持盒的隔室,允许一个或多个香味或无味物质从该装置分配到外部环境的开口以及形成在隔室和开口之间的一个或多个输送通道,其中 所述一个或多个输送通道中的每一个构造成将来自相应室的香味物质输送到所述开口以从所述一种或多种香味物质输送气味; 以及致动器开关,其布置在相应的输送通道中,并基于施加的信号快速操作以在打开位置和关闭位置之间移动,以选择性地允许来自相应输送路径的香味或无味物质的通过。
    • 10. 发明申请
    • METHODS AND ARTICLES FOR REMOTE MAGNETICALLY INDUCED TREATMENT OF CANCER AND OTHER DISEASES, AND METHOD FOR OPERATING SUCH ARTICLE
    • 用于远程磁性诱导治疗癌症及其他疾病的方法和文章及其操作方法
    • WO2005065282A2
    • 2005-07-21
    • PCT/US2004/043459
    • 2004-12-23
    • THE REGENTS OF THE UNIVERSITY OF CALIFORNIAJIN, SunghoPISANIC, Thomas
    • JIN, SunghoPISANIC, Thomas
    • A61K41/00A61K47/48A61N2/02A61N2/06
    • A61N2/06A61K41/0028A61K41/0052A61K47/6923A61K47/6929A61N2/02
    • This invention describes unique treatment methods and innovative articles that can be placed in a human or animal body to enable controlled destruction of diseased tissue. The methods include destruction of diseased cells and tissues by magnetically controlled motion and an externally controllable drug delivery process with a capability to start and stop the drug delivery at any time, for any duration. This invention provides two approaches to diseased cell destruction, (1) magneto-mechanical disturbance of cell structure ( e.g. cancer cells) for cell lysis and (2) magnetically activated drug release at local regions ( e.g. tumors) from a magnetic-particle-containing drug reservoir. The invention also provides combinations of both the above treatments for dual therapy. It further combines one or both of the treatments with magnetic hyperthermia for multifunctional cell destruction therapy. The approaches can be combined with magnetic MRI for monitoring the accuracy of placement as well as for following up the cancer destruction progress and appropriate reprogramming of the magneto-mechanical therapy and remote-controlled drug release.
    • 本发明描述了可以放置在人体或动物体内的独特的治疗方法和创新的制品,以实现病变组织的受控破坏。 所述方法包括通过磁力控制的运动破坏患病细胞和组织,以及外部可控的药物递送过程,其能够在任何时间内随时开始和停止药物递送。 本发明提供了两种病变细胞破坏的方法,(1)用于细胞裂解的细胞结构(例如癌细胞)的磁机械扰动和(2)来自含磁粉的局部区域(例如肿瘤)的磁性活化药物释放 药库 本发明还提供了用于双重治疗的上述两种治疗的组合。 它进一步结合了一种或两种治疗与磁疗热疗用于多功能细胞破坏治疗。 这些方法可以与磁性MRI结合,用于监测放置的准确性,以及跟踪癌症破坏进展和磁力机械治疗和远程控制药物释放的适当重新编程。