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1. 发明申请

WO2008126057A2 PERSONAL CARE COMPOSITIONS COMPRISING AN ANTIMICROBIAL BLEND OF ESSENTIAL OILS OR CONSTITUENTS THEREOF 审中-公开
标题翻译：包含基本油或其组成物的抗微生物混合物的个人护理组合物
公开(公告)号：WO2008126057A2
公开(公告)日：2008-10-23
申请号：PCT/IB2008/051444
申请日：2008-04-15
申请人： THE PROCTER & GAMBLE COMPANY , SCOTT, Douglas, Craig , SANKER, Lowell, Alan , GOULBOURNE, Eric, Altman, Jr.
发明人： SCOTT, Douglas, Craig , SANKER, Lowell, Alan , GOULBOURNE, Eric, Altman, Jr.
CPC分类号： A61K8/33 , A61K8/0216 , A61K8/347 , A61K8/498 , A61K8/922 , A61Q11/00 , A61Q11/02 , A61Q17/04
摘要： Disclosed are personal care compositions, including compositions for oral, throat and skin care comprising a blend of naturally occurring flavor or perfume ingredients or essential oils containing such ingredients, wherein the blend provides excellent antimicrobial activity and comprises at least two components, a first acyclic component selected from citral, neral, geranial, geraniol and nerol and a second cyclic-containing component selected from eucalyptol, carvacrol and eugenol. Preferably, the blend comprises 3, 4, 5 or more of the above components. Greater synergy in terms of antimicrobial efficacy may be obtained the more different components are blended together. The present compositions are effective in killing, suppressing the growth of and/or altering metabolism of microorganisms including those which cause undesirable oral cavity conditions including plaque, caries, calculus, gingivitis, periodontal disease and malodor. Optionally the blend further comprises additional antimicrobial and/or anti-inflammatory components, preferably naturally-occurring as well.
摘要翻译：公开了个人护理组合物，包括用于口服，咽喉和皮肤护理的组合物，其包含天然存在的风味剂或香料成分或含有这些成分的精油的混合物，其中所述共混物提供优异的抗微生物活性，并且包含至少两种组分，第一无环组分选自柠檬醛，柠檬酸，香叶醇，香叶醇和橙花醇，以及选自桉树脑，香芹酚和丁子香酚的第二含环状成分。优选地，共混物包含3,4,5或更多的上述组分。可以获得更多不同组分混合在一起的抗菌效力方面的更大的协同作用。本发明的组合物有效地杀死，抑制微生物的生长和/或改变代谢，包括引起不希望的口腔病症（包括斑块，龋齿，结石，牙龈炎，牙周病和恶臭）的代谢。任选地，共混物还包含另外的抗微生物和/或抗炎成分，优选天然存在的。

2. 发明申请

WO2012012385A2 COMPOSITIONS COMPRISING DERIVATIVES OF ESSENTIAL OIL COMPOUNDS AND USE IN PERSONAL CARE PRODUCTS 审中-公开
标题翻译：包含基本油性化合物衍生物和用于个人护理产品的组合物
公开(公告)号：WO2012012385A2
公开(公告)日：2012-01-26
申请号：PCT/US2011/044476
申请日：2011-07-19
申请人： THE PROCTER & GAMBLE COMPANY , SCOTT, Douglas, Craig , SANKER, Lowell, Alan , SWAINE JR., Robert, Leslie
发明人： SCOTT, Douglas, Craig , SANKER, Lowell, Alan , SWAINE JR., Robert, Leslie
IPC分类号： A61K36/54 , A61K36/534 , A61K36/45 , A61K8/21 , A61K8/97 , A61K8/33 , A61K31/352 , A61K31/216 , A61K31/225 , A61P31/02 , A61Q5/02 , A61Q11/00 , A61K8/22 , A61K8/55
CPC分类号： A61K31/216 , A61K8/0216 , A61K8/33 , A61K8/34 , A61K8/347 , A61K8/36 , A61K8/37 , A61K8/922 , A61K31/225 , A61K31/352 , A61K36/45 , A61K36/534 , A61K36/54 , A61Q11/00 , A61Q11/02 , A61Q17/005
摘要： Compositions containing one or more derivatives of essential oil compounds for use in personal care compositions, such as compositions for oral, throat and skin care are disclosed. These derivatives include acetals of parent essential oil aldehydes and ketones; esters or ethers of parent essential oil alcohols and phenolics; and esters of parent essential oil acids. Examples of parent essential oil aldehydes and ketones include citral, cinnamic aldehyde, ρ-anisaldehyde, vanillin, ethyl vanillin, heliotropin, carvone, and menthone. Examples of parent essential oil alcohols and phenolics include thymol, eugenol, isoeugenol, dihydroeugenol, carvacrol, carveol, geraniol, nerol, vanillyl alcohol, heliotropyl alcohol, ρ-anisyl alcohol, cinnamyl alcohol and β-ionol. Examples of parent essential oil acids include ρ-anisic acid, cinnamic acid, vanillic acid and geranic acid. The present compositions comprising essential oil derivatives are useful as base flavor or base perfume for incorporation into personal care products and to provide other benefits including antimicrobial efficacy. Optionally the compositions will contain additional antimicrobially- or anti-inflammatory-effective components including those also derived from plant essential oils or synthetic versions thereof.
摘要翻译：公开了含有用于个人护理组合物的一种或多种精油化合物衍生物的组合物，例如用于口腔，咽喉和皮肤护理的组合物。这些衍生物包括母体精油醛和酮的缩醛; 母体精油醇和酚类的酯或醚; 和母体精油酸的酯。父母精油醛和酮的实例包括柠檬醛，肉桂醛，α-茴香醛，香草醛，乙基香草醛，延胡索酮，香芹酮和薄荷酮。母体精油醇和酚类物质的实例包括百里香酚，丁子香酚，异丁子香酚，二氢丁子香酚，香芹酚，香芹醇，香叶醇，橙花醇，香草醇，庚醇，α-茴香醇，肉桂醇和β-离子醇。父母精油酸的实例包括γ-茴香酸，肉桂酸，香草酸和香叶酸。包含精油衍生物的本发明组合物可用作并入个人护理产品中的基础香料或碱性香料，并提供包括抗微生物功效在内的其它益处。任选地，组合物将包含另外的抗微生物或抗炎有效成分，包括还衍生自植物精油或其合成形式的组分。

3. 发明申请

WO2007111616A1 ORAL CARE COMPOSITIONS PROVIDING ENHANCED WHITENING AND STAIN PREVENTION 审中-公开
标题翻译：口腔护理组合物，提供增强白色和不良预防
公开(公告)号：WO2007111616A1
公开(公告)日：2007-10-04
申请号：PCT/US2006/015536
申请日：2006-04-20
申请人： THE PROCTER & GAMBLE COMPANY , SCOTT, Douglas, Craig , GLANDORF, William, Michael , DRAKE, Phillip, Asa
发明人： SCOTT, Douglas, Craig , GLANDORF, William, Michael , DRAKE, Phillip, Asa
IPC分类号： A61K8/55 , A61Q11/00
CPC分类号： A61Q11/00 , A61K8/24 , A61K8/55 , A61K2800/52
摘要： The present invention relates to oral care compositions containing an agent having substantivity to teeth, in particular polyphosphorylated compounds having at least 3 phosphate groups such as linear condensed polyphosphate polymers and phytate, which in combination with a tooth bleaching agent such as peroxide provide enhanced whitening and stain prevention of teeth.
摘要翻译：本发明涉及含有对牙齿具有亲和性的试剂的口腔护理组合物，特别是具有至少3个磷酸基团的多磷酸化化合物，例如线性缩合多磷酸盐聚合物和植酸盐，其与牙齿漂白剂如过氧化物组合提供增强的增白和牙齿防污。

4. 发明申请

WO2011056748A2 ORAL COMPOSITIONS FOR TREATMENT OF DRY MOUTH 审中-公开
标题翻译：口服组合物治疗干燥剂
公开(公告)号：WO2011056748A2
公开(公告)日：2011-05-12
申请号：PCT/US2010/054956
申请日：2010-11-01
申请人： THE PROCTER & GAMBLE COMPANY , SCOTT, Douglas, Craig , SALLOUM, David, S. , SNIDER, Ann, Gilligan , JOHNSON, Christine, Lula
发明人： SCOTT, Douglas, Craig , SALLOUM, David, S. , SNIDER, Ann, Gilligan , JOHNSON, Christine, Lula
IPC分类号： A61K8/22 , A61K8/81 , A61Q11/00
CPC分类号： A61Q11/00 , A61K8/86
摘要： An oral care composition for the treatment of dry mouth comprising a polyethylene oxide with a molecular weight from about 200,000 to about 7,000,000, an anti-bacterial agent, and a sensate.
摘要翻译：一种用于治疗口干的口腔护理组合物，其包含分子量为约200,000至约700,000的聚环氧乙烷，抗菌剂和敏感剂。

5. 发明申请

WO2007056612A2 DENTURE ADHESIVE ARTICLES 审中-公开
公开(公告)号：WO2007056612A2
公开(公告)日：2007-05-18
申请号：PCT/US2006/044035
申请日：2006-11-09
申请人： THE PROCTER & GAMBLE COMPANY , RAJAIAH, Jayanth , WILDER, Elizabeth, Anne , HAMERSKY, Mark, William , SMITH, Steven, Daryl , SCOTT, Douglas, Craig
发明人： RAJAIAH, Jayanth , WILDER, Elizabeth, Anne , HAMERSKY, Mark, William , SMITH, Steven, Daryl , SCOTT, Douglas, Craig
CPC分类号： A61K6/0026 , C08L27/06 , C08L77/10 , C08L25/08 , C08L23/06 , C08L23/12 , C08L31/04 , C08L29/04 , C08L5/04 , C08L89/04 , C08L33/26 , C08L33/08 , C08L39/06 , C08L1/12
摘要： The present invention relates to a denture adhesive article comprising: a) a safe and effective adhesive amount of a water soluble denture adhesive component; b) a safe and effective amount of a component selected from the group consisting of a water soluble plasticizer, a water soluble carrier, and mixtures thereof; wherein the article is bioerodible; and wherein the article has dry tack.
摘要翻译：本发明涉及义齿粘合剂制品，其包含：a）安全有效的粘合剂量的水溶性义齿粘合剂组分; b）安全有效量的选自水溶性增塑剂，水溶性载体及其混合物的组分; 其中所述制品是生物可蚀解的; 并且其中该物品具有干粘性。

6. 发明申请

WO2005058268A1 COMPOSITIONS AND METHODS OF DELIVERING BLEACHING AGENTS TO TEETH 审中-公开
标题翻译：将漂白剂递送给TEETH的组合物和方法
公开(公告)号：WO2005058268A1
公开(公告)日：2005-06-30
申请号：PCT/US2004/042974
申请日：2004-12-17
申请人： THE PROCTER & GAMBLE COMPANY , SCOTT, Douglas, Craig , GHOSH, Chanchal, Kumar
发明人： SCOTT, Douglas, Craig , GHOSH, Chanchal, Kumar
IPC分类号： A61K7/16
CPC分类号： A61K8/8111 , A61K8/22 , A61Q11/00
摘要： The present invention relates to compositions and methods of whitening teeth of a subject in need thereof, by applying a safe and effective amount of a composition to a plurality of teeth, the composition comprising: a. a safe and effective amount of a bleaching agent; b. a safe and effective amount of a water insoluble solid phase; c. a safe and effective amount of a water soluble liquid phase; wherein the ratio of the water insoluble solid phase to water soluble liquid phase is from about 1:4 to about 4:1; wherein the composition is applied for a sufficient period of time to achieve whitening; and wherein in one embodiment the composition has a Whitening Index of from about 0.5 to about 4. The composition comprises a hydrophobically modified polymer. The present invention also relates to a delivery system comprising the present compositions used with an integral carrier, e.g. a strip material, dental tray or sponge material.
摘要翻译：本发明涉及通过将安全有效量的组合物施用于多个牙齿来增加有需要的受试者牙齿的组合物和方法，所述组合物包含：a。安全有效量的漂白剂; 湾安全有效量的水不溶性固相; C。安全有效量的水溶性液相; 其中水不溶性固相与水溶性液相的比例为约1:4至约4:1; 其中组合物施用足够的时间以实现美白; 并且其中在一个实施方案中，所述组合物具有约0.5至约4的美白指数。所述组合物包含疏水改性的聚合物。本发明还涉及包含与整体载体一起使用的本发明组合物的递送系统。条带材料，牙科托盘或海绵材料。

7. 发明申请

WO2011056759A2 ORAL COMPOSITIONS FOR TREATMENT OF DRY MOUTH 审中-公开
标题翻译：用于治疗干口疮的口服组合物
公开(公告)号：WO2011056759A2
公开(公告)日：2011-05-12
申请号：PCT/US2010/055027
申请日：2010-11-02
申请人： THE PROCTER & GAMBLE COMPANY , SALLOUM, David, S. , SCOTT, Douglas, Craig , WHITE, Donald, James, Jr. , HAUGHT, John, Christian , HO, Begonia, Y. , KLUKOWSKA, Malgorzata
发明人： SALLOUM, David, S. , SCOTT, Douglas, Craig , WHITE, Donald, James, Jr. , HAUGHT, John, Christian , HO, Begonia, Y. , KLUKOWSKA, Malgorzata
IPC分类号： A61K31/765 , A61Q11/00
CPC分类号： A61K8/21 , A61K8/27 , A61K8/86 , A61K31/765 , A61K33/30 , A61Q11/00 , A61K2300/00
摘要： An oral care composition for the treatment of dry mouth comprising a polyethylene oxide with a molecular weight from about 200,000 to about 7,000,000, an anti-bacterial agent, and a sensate.
摘要翻译：用于治疗口干的口腔护理组合物，其包含分子量为约200,000至约7,000,000的聚环氧乙烷，抗菌剂和感觉剂。

8. 发明申请

WO2004047784A1 CHEWABLE SOLID UNIT DOSAGE FORMS AND METHODS FOR DELIVERY OF ACTIVE AGENTS INTO OCCLUSAL SURFACES OF TEETH 审中-公开
标题翻译：可用的实体单位剂量形式和用于将活性药剂递送到牙膏的表面的方法
公开(公告)号：WO2004047784A1
公开(公告)日：2004-06-10
申请号：PCT/US2003/037879
申请日：2003-11-25
申请人： THE PROCTER & GAMBLE COMPANY
发明人： SCOTT, Douglas, Craig , EVERSOLE, Sandra, Lynn , BURGESS, Steven, Carl , BEST, John, Michael , FALLER, Robert, Vincent
IPC分类号： A61K7/16
CPC分类号： A61K8/731 , A61K9/0056 , A61K2800/52 , A61Q11/00
摘要： The present invention relates to methods and an oral care composition for topical, oral administration in a human or other animal comprising: a. from about 1% to about 40%, by weight of the composition, of a retentive agent selected from the group consisting of water soluble hydrophilic gums, water soluble hydrophilic polymers, and mixtures thereof, the retentive agent having the property of hydrating upon exposure to water or saliva resulting in the composition forming an intact hydrated mass to provide a Retention Index of about 1 to about 4; and b. a safe and effective amount of a topical, oral care carrier; wherein the composition is a non-cariogenic, chewable solid unit dosage form; and the composition comprises less than about 65% by weight of water insoluble particulates.The present invention further relates to an oral care dentifrice composition comprising: a. from about 30% to about 65%, by weight of the composition, of a water insoluble, particulate retentive agent having a water solubility of less than about 1g/30g at 25°C; b. a safe and effective amount of an oral care active; c.a safe and effective amount of a surfactant; d. a safe and effective amount of a buffer; wherein the composition is a chewable dentifrice solid unit dosage form, is non-effervescent, non-cariogenic; and wherein the composition has a Retention Index of from about 1 to about 4.
摘要翻译：本发明涉及在人或其他动物中局部，口服给药的方法和口腔护理组合物，其包含：a。占组合物重量的约1％至约40％的选自水溶性亲水性树胶，水溶性亲水性聚合物及其混合物的保持剂，所述保持剂具有在暴露于水或唾液导致组合物形成完整的水合物质以提供约1至约4的保留指数; 和b。安全有效量的局部口服护理载体; 其中所述组合物是非致龋剂的可咀嚼的固体单位剂型; 并且所述组合物包含小于约65重量％的水不溶性颗粒。本发明还涉及口腔护理洁齿剂组合物，其包含：a。在25℃下水溶性小于约1g / 30g的水不溶性颗粒保持剂约占组合物重量的约30％至约65％; 湾安全有效量的口腔护理活动; c.a安全有效量的表面活性剂; 天。安全有效量的缓冲液; 其中所述组合物是可咀嚼的洁牙剂固体单位剂型，是非泡腾的，非致龋的; 并且其中所述组合物具有约1至约4的保留指数。

9. 发明申请

WO2013192382A2 MOUTH RINSE EMULSIONS 审中-公开
公开(公告)号：WO2013192382A2
公开(公告)日：2013-12-27
申请号：PCT/US2013/046731
申请日：2013-06-20
申请人： THE PROCTER & GAMBLE COMPANY
发明人： SCOTT, Douglas, Craig , RAMJI, Niranjan , TIPPER, Bruce, Ernest
IPC分类号： A61K8/92 , A61Q11/00 , A61K8/06 , C12Q1/18
CPC分类号： A61Q17/005 , A61K8/062 , A61K8/416 , A61Q11/00 , C12Q1/18
摘要： Disclosed are oral care mouth rinse compositions formulated as stable oil-in-water emulsions comprising: (a) at least about 0.025 % by weight of a quaternary ammonium antimicrobial agent, (b) at least about 0.05 % by weight of an essentially water-insoluble volatile oil, and (c) at least about 50 % by weight water, wherein the emulsion comprises oil droplets having an average mean particle size of about 350 nm or less. Examples of quaternary ammonium antimicrobial agent include cetylpyridinium chloride (CPC), tetradecylpyridinium chloride, N-tetradecyl-4-ethyl pyridinium chloride or domiphen bromide.
摘要翻译：公开了配制为稳定的水包油乳液的口腔护理口腔漂洗组合物，其包含：（a）至少约0.025重量％的季铵抗微生物剂，（b）至少约0.05重量％的基本上水 - 不溶性挥发油，和（c）至少约50重量％的水，其中所述乳液包含平均粒度为约350nm或更小的油滴。季铵抗菌剂的实例包括氯化十六烷基吡啶（CPC），氯化十四烷基吡啶，氯化N-十四烷基-4-乙基吡啶鎓或溴化三苯胺。

10. 发明申请

WO2004047785A1 CHEWABLE SOLID UNIT DOSAGE FORMS AND METHODS FOR DELIVERY OF ACTIVE AGENTS INTO OCCLUSAL SURFACES OF TEETH 审中-公开
标题翻译：可用的实体单位剂量形式和用于将活性药剂递送到牙膏的表面的方法
公开(公告)号：WO2004047785A1
公开(公告)日：2004-06-10
申请号：PCT/US2003/037880
申请日：2003-11-25
申请人： THE PROCTER & GAMBLE COMPANY
发明人： SCOTT, Douglas, Craig , EVERSOLE, Sandra, Lynn , BURGESS, Steven, Carl , BEST, John, Michael , FALLER, Robert, Vincent
IPC分类号： A61K7/16
CPC分类号： A61K8/731 , A61K9/0056 , A61K2800/52 , A61Q11/00
摘要： The present invention relates to methods and an oral care composition for topical, oral administration in a human or other animal comprising: a. from about 1% to about 40%, by weight of the composition, of a retentive agent selected from the group consisting of water soluble hydrophilic gums, water soluble hydrophilic polymers, and mixtures thereof, the retentive agent having the property of hydrating upon exposure to water or saliva resulting in the composition forming an intact hydrated mass to provide a Retention Index of about 1 to about 4; and b. a safe and effective amount of a topical, oral care carrier; wherein the composition is a non-cariogenic, chewable solid unit dosage form; and the composition comprises less than about 65% by weight of water insoluble particulates.The present invention further relates to an oral care dentifrice composition comprising: a. from about 30% to about 65%, by weight of the composition, of a water insoluble, particulate retentive agent having a water solubility of less than about 1g/30g at 25°C; b. a safe and effective amount of an oral care active; c.a safe and effective amount of a surfactant; d. a safe and effective amount of a buffer; wherein the composition is a chewable dentifrice solid unit dosage form, is non-effervescent, non-cariogenic; and wherein the composition has a Retention Index of from about 1 to about 4.
摘要翻译：本发明涉及在人或其他动物中局部，口服给药的方法和口腔护理组合物，其包含：a。占组合物重量的约1％至约40％的选自水溶性亲水性树胶，水溶性亲水性聚合物及其混合物的保持剂，所述保持剂具有在暴露于水或唾液导致组合物形成完整的水合物质以提供约1至约4的保留指数; 和b。安全有效量的局部口服护理载体; 其中所述组合物是非致龋剂的可咀嚼的固体单位剂型; 并且所述组合物包含小于约65重量％的水不溶性颗粒。本发明还涉及口腔护理洁齿剂组合物，其包含：a。在25℃下水溶性小于约1g / 30g的水不溶性颗粒保持剂约占组合物重量的约30％至约65％; 湾安全有效量的口腔护理活动; c.a安全有效量的表面活性剂; 天。安全有效量的缓冲液; 其中所述组合物是可咀嚼的洁牙剂固体单位剂型，是非泡腾的，非致龋的; 并且其中所述组合物具有约1至约4的保留指数。

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