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    • 1. 发明申请
    • METHODS AND COMPOSITIONS FOR HYDROPHOBIC MODIFICATION OF ORAL CAVITY SURFACES
    • 口腔修复表面的疏水性修饰方法及组合物
    • WO2011031807A2
    • 2011-03-17
    • PCT/US2010/048186
    • 2010-09-09
    • THE PROCTER & GAMBLE COMPANYBAIG, Arif, AliRAJAIAH, JayanthDECKNER, George, EndelGLANDORF, William, Michael
    • BAIG, Arif, AliRAJAIAH, JayanthDECKNER, George, EndelGLANDORF, William, Michael
    • A61Q11/00
    • A61Q11/00A61K8/24A61K8/55A61K8/556A61Q11/02
    • Oral care compositions containing agents that are effective for treating and modifying teeth and mucosal surfaces to be hydrophobic are disclosed. Hydrophobic modification of teeth and other oral cavity surfaces imparts a variety of end use benefits including prevention of caries, erosion, wear, staining, sensitivity and desquamation as well as providing shine, smoothness and positive tooth feel benefits. The compositions contain selected surface active organophosphate compounds that deposit and adhere to teeth and other oral cavity surfaces forming a hydrophobic coating having prolonged retention thereon. By forming a "hydrophobic coating" on the oral cavity surface is meant that the hydrophobic character of the surface is increased as measured, for example, by an increase of at least about 10 degrees in the water contact angle of the surface after treatment. The increased hydrophobic character of the surface is maintained for a period of at least about 5 minutes and desirably longer such as at least about 10, at least about 20 or at least about 30 minutes. The compositions may contain additional hydrophobic materials to further increase hydrophobicity of the surface and/or functionality of the coating to provide surface protection and many other benefits.
    • 公开了含有有效治疗和改变牙齿和粘膜表面是疏水性的试剂的口腔护理组合物。 牙齿和其他口腔表面的疏水改性赋予各种最终用途的优点,包括预防龋齿,侵蚀,磨损,染色,敏感性和脱屑,以及提供光泽,平滑度和积极的牙齿感受益处。 组合物含有选择的表面活性有机磷酸酯化合物,其沉积并粘附到牙齿和其它口腔表面,形成其上具有延长保留性的疏水涂层。 通过在口腔表面上形成“疏水性涂层”是指表面的疏水特性例如通过在处理后表面的水接触角增加至少约10度来测量而增加。 表面增加的疏水特性保持至少约5分钟,期望更长,例如至少约10,至少约20或至少约30分钟。 组合物可以含有另外的疏水材料以进一步增加涂层的表面和/或功能性的疏水性,以提供表面保护和许多其它益处。
    • 3. 发明申请
    • ORAL COMPOSITIONS PROVIDING ENHANCED OVERALL CLEANING
    • 口服组合物提供增强的整体清洁
    • WO2003024415A2
    • 2003-03-27
    • PCT/US2002/029035
    • 2002-09-12
    • THE PROCTER & GAMBLE COMPANY
    • MAJETI, SatyanarayanaBAPAT, Niteen, VasantCLYMER, Paula, DeniseRENO, Elizabeth, AnnGLANDORF, William, MichaelKOVACS, Stephen, Andras
    • A61K7/16
    • A61Q11/02A61K8/24A61K8/8182A61Q11/00
    • Disclosed are oral care compositions and methods for overall cleaning, whitening and preventing, reducing or removing surface deposited stains on natural teeth and dental prosthesis, the compositions comprising in an orally acceptable carrier at least 0.1% by weight of a water-soluble or water-dispersible copolymer prepared by copolymerizing one or a mixture of vinyl pyrrolidone (VP) monomers with one or a mixture of C1-C19 alkyl carboxylic acid (AC) C2-C12 alkenyl ester monomers. Preferably, the compositions further comprise one or a mixture of other oral care agents selected from a water soluble alkali metal or ammonium tripolyphosphate in an amount at least about 0.5% by weight of the composition, an abrasive, preferably a precipitated silica abrasive, in an amount at least about 6% by weight of the composition and a bleaching agent in an amount at least about 0.1% by weight of the composition. This invention further relates to methods of cleaning, whitening and polishing natural teeth and dental prosthesis and of preventing, reducing or removing surface deposited stains from teeth by administering the present compositions.
    • 公开了用于全面清洁,增白和预防,减少或去除天然牙齿和假牙上的表面沉积污渍的口腔护理组合物和方法,所述组合物在口腔可接受的载体中包含至少0.1重量% 通过共聚乙烯基吡咯烷酮(VP)单体的一种或混合物与C 1 -C 19烷基羧酸(AC)C 2 -C 12烯基酯单体的一种或混合物制备的水溶性或水分散性共聚物。 优选地,所述组合物进一步包含一种或其它口腔护理剂的混合物,所述其它口腔护理剂选自以组合物重量计至少约0.5%的水溶性碱金属或铵三聚磷酸盐,研磨剂,优选沉淀二氧化硅研磨剂, 的量占组合物重量的至少约6%,漂白剂的量至少为组合物重量的约0.1%。 本发明进一步涉及通过施用本发明组合物来清洁,增白和抛光天然牙齿和假牙以及防止,减少或去除牙齿表面沉积的污渍的方法。
    • 9. 发明申请
    • ORAL CARE COMPOSITIONS COMPRISING DICARBOXY FUNCTIONALIZED POLYORGANOSILOXANES
    • 包含二氧化硅官能化聚硅氧烷的口腔护理组合物
    • WO2003094877A1
    • 2003-11-20
    • PCT/US2003/014694
    • 2003-05-09
    • THE PROCTER & GAMBLE COMPANY
    • MAJETI, SatyanarayanaRENO, Elizabeth, Ann, BrownKOVACS, Stephen, AndrasOLIER, PhilippeGLANDORF, William, Michael
    • A61K7/16
    • A61K8/893A61Q11/00
    • Disclosed are compositions and methods for treating and modifying surfaces and for enhancing delivery of active agents to surfaces treated with the compositions, which comprise siloxane polymers functionalized with pendant moieties comprising anionic groups, specifically carboxylic acid groups. When applied to a suitable surface, the present composition comprising the carboxy functionalized siloxane polymers forms a substantially hydrophobic coating on the treated surface. These polymers effectively deposit on surfaces that have cationic sites, which are capable of forming bonds or linkages with the anionic groups of the polymer. The treated surface becomes hydrophobic due to the deposition of the carboxy functionalized siloxane polymer, which then imparts a variety of end use benefits to that surface such as ease of cleaning, stain removal and prevention, whitening, etc. The carboxy functionalized siloxane polymer further acts as a carrier to deposit active agents onto the surface and to improve retention and efficacy of said actives on the treated surface. The present compositions are useful in a variety of applications including oral care, hair and skin care, personal care, cosmetics, and fabric and hard surface cleaning and conditioning. Examples are oral compositions for use in cleaning and whitening of natural teeth and dental prosthesis; for preventing, reducing or removing plaque, calculus and surface deposited stains on teeth; and for providing shine, smoothness and positive feel benefits to teeth, the compositions comprising at least about 0.1% by weight of a dicarboxy functionalized siloxane polymer in a formulation that effectively deposits the polymer to teeth and other oral surfaces.
    • 公开了用于处理和改性表面并用于增强活性剂递送至用组合物处理的表面的组合物和方法,该组合物包含用包含阴离子基团的侧基部分官能化的硅氧烷聚合物,特别是羧酸基团。 当施用于合适的表面时,包含羧基官能化的硅氧烷聚合物的本发明组合物在经处理的表面上形成基本疏水的涂层。 这些聚合物有效地沉积在具有阳离子位点的表面上,其能够与聚合物的阴离子基团形成键或键。 由于羧基官能化的硅氧烷聚合物的沉积,被处理的表面变得疏水,其然后赋予该表面多种最终用途的优点,例如清洁方便,除污和防止白化等。羧基官能化的硅氧烷聚合物进一步起作用 作为将活性剂沉积到表面上并且改善所述活性物质在被处理表面上的保留性和功效的载体。 本发明的组合物可用于各种应用,包括口腔护理,毛发和皮肤护理,个人护理,化妆品和织物以及硬表面清洁和调理。 实例是用于天然牙齿和牙齿假体的清洁和增白的口腔组合物; 用于防止,减少或去除牙齿上的斑块,结石和表面沉积的污渍; 并且为了提供光泽,平滑度和对牙齿的正面感觉益处,组合物在制剂中包含至少约0.1重量%的二羧基官能化硅氧烷聚合物,其有效地将聚合物沉积到牙齿和其它口腔表面。