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1. 发明申请

WO2014047398A1 MODULATION OF ASYMMETRIC PROLIFERATION 审中-公开
标题翻译：不对称增殖的调制
公开(公告)号：WO2014047398A1
公开(公告)日：2014-03-27
申请号：PCT/US2013/060842
申请日：2013-09-20
申请人： THE GENERAL HOSPITAL CORPORATION , RAMASWAMY, Sridhar
发明人： RAMASWAMY, Sridhar
IPC分类号： A61K31/352 , A61K31/437 , A61K31/495 , A61K31/5025 , A61P35/00
CPC分类号： A61K31/69
摘要： Provided herein are methods and compositions related to modulation of the rate of asymmetric proliferation of cancer cells. In some embodiments, the methods described herein relate to the treatment of cancer, at least in part, via the modulation of the rate of asymmetric proliferation of cancer cells.
摘要翻译：本文提供了与调节癌细胞不对称增殖速率有关的方法和组合物。在一些实施方案中，本文所述的方法涉及至少部分地通过调节癌细胞的不对称增殖速率来治疗癌症。

2. 发明申请

WO2015100257A1 METHODS AND ASSAYS FOR DETERMINING REDUCED BRCA1 PATHWAY FUNCTION IN A CANCER CELL 审中-公开
标题翻译：用于确定癌细胞中减少的BRCA1途径功能的方法和测定
公开(公告)号：WO2015100257A1
公开(公告)日：2015-07-02
申请号：PCT/US2014/071948
申请日：2014-12-22
申请人： THE GENERAL HOSPITAL CORPORATION
发明人： SGROI, Dennis , MCMULLIN, Ryan, P. , WITTNER, Ben , RAMASWAMY, Sridhar
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/158
摘要： Provided herein are methods and assays that can be used to predict whether a subject will or will not respond to a cancer treatment comprising a PARP inhibitor and a DNA damage-inducing chemotherapeutic.
摘要翻译：本文提供了可用于预测受试者是否将对包括PARP抑制剂和DNA损伤诱导化疗的癌症治疗反应的方法和测定法。

3. 发明申请

WO2007070358A3 DETERMINING ADVERTISEMENTS USING USER INTEREST INFORMATION AND MAP-BASED LOCATION INFORMATION 审中-公开
公开(公告)号：WO2007070358A3
公开(公告)日：2007-06-21
申请号：PCT/US2006/046782
申请日：2006-12-08
申请人： Google, Inc. , GLASSMAN, Steve , JOSEPH, Joshy , KILDAY, Bill , NGUYEN, Giao , PREUSS, Dominic , RAMASWAMY, Sridhar
发明人： GLASSMAN, Steve , JOSEPH, Joshy , KILDAY, Bill , NGUYEN, Giao , PREUSS, Dominic , RAMASWAMY, Sridhar
IPC分类号： G06Q30/00 , G07G1/14
摘要： In response to a query for information in a geographic region or at a location, ranked ads may be plotted on, or in association with, a map (e.g., as a list beside the map), satellite photo, or any other form of visual representation of geographic information (referred to generally as "maps"). Sponsored ads might be shown in a dedicated place and/or might be elevated above other non-sponsored search results (e.g., Yellow Page listings). The number of ads shown in the list and/or plotted on the map could vary as a function of the resolution of the map or geographic image. The ads could be ranked or scored, and attributes or features of various ads may be a function of such a score or ranking. The plots on the map might be selectable to provide a pop-up with further information and possibly sponsored information (such as images, further ads, etc).

4. 发明申请

WO2008021906A2 INTEREST TARGETING 审中-公开
标题翻译：兴趣迎接
公开(公告)号：WO2008021906A2
公开(公告)日：2008-02-21
申请号：PCT/US2007/075514
申请日：2007-08-08
申请人： GOOGLE INC. , WISEMAN, Leora Ruth , VENKATARAMA, Shivakumar , RAMASWAMY, Sridhar
发明人： WISEMAN, Leora Ruth , VENKATARAMA, Shivakumar , RAMASWAMY, Sridhar
IPC分类号： G06Q30/00 , G06Q40/00
CPC分类号： G06F17/30398 , G06F3/0482 , G06F3/04842 , G06F17/30554 , G06F17/30867 , G06Q30/02 , G06Q30/0256 , G06Q30/0275 , G06Q30/0277 , G06Q40/04
摘要： An advertisement can be presented by associating a label with an advertisement, receiving input from a user, wherein the input comprises one or more labels, identifying a match between the label associated with the advertisement and the input, and presenting the advertisement to the user. A bid further can be received for presenting the advertisement in response to input from a user that includes the associated label and an advertisement presentation order can be determined based on one or more of the bid, a click-through rate of the advertisement, and a conversion rate of the advertisement. Additionally, a negative label can be associated with the advertisement. Further, an additional input comprising one or more labels can be received from the user, a match can be identified between the negative label and the received additional input, and it can be determined not to present the advertisement based on the identified match.
摘要翻译：可以通过将标签与广告相关联，从用户接收输入来呈现广告，其中输入包括一个或多个标签，标识与广告相关联的标签与输入之间的匹配，以及向用户呈现广告。还可以收到用于响应于包括关联标签的用户的输入来呈现广告的投标，并且可以基于投标中的一个或多个，广告的点击率和广告显示顺序来确定广告呈现顺序广告转换率。另外，负面标签可以与广告相关联。此外，可以从用户接收包括一个或多个标签的附加输入，可以在负标签和接收的附加输入之间识别匹配，并且可以基于所识别的匹配来确定不呈现广告。

5. 发明申请

WO2005024667A1 DETERMINING AND/OR USING LOCATION INFORMATION IN AN AD SYSTEM 审中-公开
标题翻译：在AD系统中确定和/或使用位置信息
公开(公告)号：WO2005024667A1
公开(公告)日：2005-03-17
申请号：PCT/US2004/027239
申请日：2004-08-23
申请人： GOOGLE, INC. , YEH, Leslie , RAMASWAMY, Sridhar , QIAN, Zhe
发明人： YEH, Leslie , RAMASWAMY, Sridhar , QIAN, Zhe
IPC分类号： G06F17/30
CPC分类号： G06F17/3087 , G06Q30/02
摘要： The usefulness, and consequently the performance, of advertisements (330) are improved by allowing businesses to better target their ads to a responsive audience. Location information is determined (or simply accepted) and used. For example, location information may be used in a relevancy (350) determination of an ad. As another example, location information (380) may be associated with price information, such as a maximum price bid. Such location information may be associated with ad performance information. Ad performance information may be tracked on the basis of location information. The content of an ad creative, and/or of a landing page may be selected and/or modified using location information. Finally, tools, such as user interfaces may be provided to allow a business to enter and/or modify location information such as location information used for targeting and location-dependent price information. The location information (380) used to target and/or score (350) ads may be include or define an area. The area may be defined by at least one geographic reference point (e.g., defined by latitude and longitude coordinates) and perhaps additional information. Thus, the area may be a circle defined by a geographic reference point and a radius, an ellipse defined by two geographic reference points and a distance sum, or a polygon defined by three or more geographic reference points.
摘要翻译：通过允许企业更好地将他们的广告定位到响应受众来改善广告（330）的有用性以及因此的性能。确定（或简单地接受）并使用位置信息。例如，可以在广告的相关性（350）确定中使用位置信息。作为另一示例，位置信息（380）可以与诸如最大价格出价的价格信息相关联。这样的位置信息可以与广告演出信息相关联。可以基于位置信息跟踪广告效果信息。可以使用位置信息来选择和/或修改广告素材的内容和/或着陆页的内容。最后，可以提供诸如用户界面的工具，以允许企业输入和/或修改位置信息，例如用于定位和位置相关价格信息的位置信息。用于定位和/或评分（350）广告的位置信息（380）可以包括或定义一个区域。该区域可以由至少一个地理参考点（例如，由纬度和经度坐标定义）和可能的附加信息来定义。因此，该区域可以是由地理参考点和半径定义的圆，由两个地理参考点定义的椭圆和距离和，或由三个或更多个地理参考点定义的多边形。

6. 发明申请

WO2003041562A3 MOLECULAR CANCER DIAGNOSIS USING TUMOR GENE EXPRESSION SIGNATURE 审中-公开
公开(公告)号：WO2003041562A3
公开(公告)日：2003-05-22
申请号：PCT/US2002/036392
申请日：2002-11-14
申请人： WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH , DANA-FARBER CANCER INSTITUTE, INC. , GOLUB, Todd, R. , MUKHERJEE, Sayan , RAMASWAMY, Sridhar , RIFKIN, Ryan , TAMAYO, Pablo
发明人： GOLUB, Todd, R. , MUKHERJEE, Sayan , RAMASWAMY, Sridhar , RIFKIN, Ryan , TAMAYO, Pablo
IPC分类号： G06F19/00
摘要： Methods are provided for the classification of disease tpyes (e.g. cancer types), outcome predictions, and treatment classes based on algorithmic classifiers used to analyze large datasets.

7. 发明申请

WO2007050344A3 SYSTEM AND METHOD FOR IDENTIFYING BOUNDS OF A GEOGRAPHICAL AREA 审中-公开
公开(公告)号：WO2007050344A3
公开(公告)日：2007-05-03
申请号：PCT/US2006/040339
申请日：2006-10-14
申请人： GOOGLE INC. , JOSEPH, Joshy , RAMASWAMY, Sridhar , ROSE, Mark
发明人： JOSEPH, Joshy , RAMASWAMY, Sridhar , ROSE, Mark
IPC分类号： G01C21/00 , G01B7/00
摘要： A system and method for determining bounds of a geographical area, such as a city, metropolis, region (e.g., state) or country. From a set of coordinates within the area (e.g., latitude/longitude coordinates), a grid of relatively small cells of geographic data is overlaid upon those coordinates and associated with the area. Each initial cell is iteratively replaced with a larger cell that encompasses the initial cell until the replacement cell intersects a cell associated with some other geographical area or some other boundary condition is met (e.g., a threshold number of replacements).

8. 发明申请

WO2007050343A2 SYSTEM AND METHOD FOR IDENTIFYING GEOGRAPHICAL AREAS THAT SIGNIFICANTLY OVERLAP A MAP VIEW 审中-公开
标题翻译：用于识别地理区域的系统和方法，其显着地覆盖地图视图
公开(公告)号：WO2007050343A2
公开(公告)日：2007-05-03
申请号：PCT/US2006/040337
申请日：2006-10-14
申请人： GOOGLE INC. , JOSEPH, Joshy , RAMASWAMY, Sridhar , ROSE, Mark
发明人： JOSEPH, Joshy , RAMASWAMY, Sridhar , ROSE, Mark
IPC分类号： G08B1/00
CPC分类号： G09B29/006 , G06Q30/02 , G06Q30/0251
摘要： A system and method for identifying, from a set of geographical areas, a set of target areas that overlap a map view or view port of a map. Target areas are defined as circles having centers and radii, as sets of geographic cells overlaying the areas, or as other polygons of geographic data. Within a view port served or to be served to a user, multiple points are defined and substantially equally spaced within the view port, such that any target area that may significantly overlap the view port (e.g., at least a threshold percentage of the view port) is likely to overlap a minimum number of the points (e.g., one). Some or all target areas are then tested for intersection with some or all of the points, and calculations may be made to determine how much the intersecting areas actually overlap the view port.
摘要翻译：用于从一组地理区域中识别与地图的地图视图或观看端口重叠的一组目标区域的系统和方法。目标区域被定义为具有中心和半径的圆，作为覆盖区域的地理单元集或者地理数据的其他多边形。在服务于或将被服务给用户的查看端口内，定义了多个点并且在该查看端口内基本上等距地间隔，使得任何可能与查看端口显着重叠的目标区域（例如，查看端口的至少阈值百分比）可能重叠最少数量的点（例如一个）。然后测试一些或所有目标区域与一些或全部点的交叉点，并且可以进行计算以确定相交区域实际上与视口重叠多少。

9. 发明申请

WO2006036965A2 REDUCED ELECTROMAGNETIC COUPLING IN INTEGRATED CIRCUITS 审中-公开
标题翻译：集成电路中的降低电磁耦合
公开(公告)号：WO2006036965A2
公开(公告)日：2006-04-06
申请号：PCT/US2005/034602
申请日：2005-09-28
申请人： TEXAS INSTRUMENTS INCORPORATED , RAMASWAMY, Sridhar , ALI, Hassan, O. , WU, Song
发明人： RAMASWAMY, Sridhar , ALI, Hassan, O. , WU, Song
IPC分类号： H03L7/00
CPC分类号： H01L27/0207 , H01L23/5223 , H01L23/5227 , H01L23/552 , H01L2224/16 , H01L2924/00011 , H01L2924/00014 , H01L2924/01019 , H01L2924/3025 , H03L7/099 , H01L2224/0401
摘要： Disclosed are integrated circuits (700) having multiple electromagnetically emissive devices, such as LC oscillators (702, 204). The devices are formed on an integrated circuit substrate and are given different planar orientations from each other. Particular integrated circuit packages disclosed are "flip-chip" packages, in which solder bumps (604) are provided on the integrated circuit substrate for flipping and mounting of the finished integrated circuit upon a printed circuit board or other substrate. The solder bumps provide conductive connections between the integrated circuit and the substrate. The orientations and positioning of the emissive devices are such that one or more of the solder bumps (604) are interposed between neighboring emissive devices (702, 704) to act as an electromagnetic shield between them.
摘要翻译：公开了具有多个电磁放射器件的集成电路（700），例如LC振荡器（702,204）。这些器件形成在集成电路衬底上并且被赋予彼此不同的平面取向。所公开的特定的集成电路封装是“倒装芯片”封装，其中在集成电路基板上提供焊料凸块（604），用于将成品集成电路翻转和安装到印刷电路板或其它基板上。焊料凸块提供集成电路和衬底之间的导电连接。发射装置的取向和定位使得一个或多个焊料凸块（604）插入在相邻的发射装置（702,704）之间以用作它们之间的电磁屏蔽。

10. 发明申请

WO2009105287A1 HYBRID ADVERTISING CAMPAIGN 审中-公开
标题翻译：混合广告运动
公开(公告)号：WO2009105287A1
公开(公告)日：2009-08-27
申请号：PCT/US2009/030339
申请日：2009-01-07
申请人： GOOGLE INC. , RAMASWAMY, Sridhar , LAI, Angela Chunwah , FOLTZ, Mark A. , BARDIN, Ariel H. , BLACK, Julie A. , HEILIG, Joerg , STANIS, Thomas R.
发明人： RAMASWAMY, Sridhar , LAI, Angela Chunwah , FOLTZ, Mark A. , BARDIN, Ariel H. , BLACK, Julie A. , HEILIG, Joerg , STANIS, Thomas R.
IPC分类号： G06Q30/00 , G06F17/30
CPC分类号： G06Q30/0271 , G06Q30/02 , G06Q30/0243 , G06Q30/0251 , G06Q30/0254 , G06Q30/0277
摘要： Keywords and placement criteria related to a campaign are received. An advertisement request that specifies a web property, e.g., a web page, is received, and keywords and placement criteria that are satisfied by the web property are identified. Based on the identified keywords and placement criteria, an advertisement to be provided with the web property is selected.
摘要翻译：收到与广告系列相关的关键字和刊登位置标准。接收到指定web属性（例如网页）的广告请求，并且识别由web属性所满足的关键字和放置标准。根据确定的关键字和放置标准，选择要提供的网络媒体资源的广告。

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