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1. 发明申请

WO2004093686A1 SHEAR MODE DIAGNOSTIC ULTRASOUND 审中-公开
标题翻译：剪切模式诊断超声波
公开(公告)号：WO2004093686A1
公开(公告)日：2004-11-04
申请号：PCT/US2004/011374
申请日：2004-04-12
申请人： THE BRIGHAM & WOMEN'S HOSPITAL, INC. , HYNYNEN, Kullervo , CLEMENT, Gregory, T.
发明人： HYNYNEN, Kullervo , CLEMENT, Gregory, T.
IPC分类号： A61B8/00
CPC分类号： A61N7/02 , A61B8/06 , A61B8/0808 , A61B8/485 , A61B8/54 , A61B17/22004 , A61N2007/0065 , A61N2007/0095
摘要： A method of diagnosing a subject by delivering ultrasound signals using shear waves includes applying a portion of an ultrasound mainbeam to a bone surface at an incident angle relative to the surface of the bone to induce shear waves in the bone, energy in the shear waves forming a substantial part of energy of first ultrasound waves at a desired region in the subject through the bone, detecting at least one of reflected and scattered energy of the applied ultrasound mainbeam, and analyzing the detected energy for a diagnostic purpose.
摘要翻译：通过使用剪切波输送超声信号来诊断受试者的方法包括以相对于骨表面的入射角将一部分超声波主干施加到骨表面，以引起骨中的剪切波，形成剪切波中的能量通过骨骼在受试者的期望区域上的第一超声波的大部分能量，检测所施加的超声波主波束的反射和散射能量中的至少一个，并且将检测到的能量分析用于诊断目的。

2. 发明申请

WO2004093994A1 SHEAR MODE THERAPEUTIC ULTRASOUND 审中-公开
标题翻译：剪切模式治疗超声
公开(公告)号：WO2004093994A1
公开(公告)日：2004-11-04
申请号：PCT/US2004/011378
申请日：2004-04-12
申请人： THE BRIGHAM & WOMEN'S HOSPITAL, INC. , HYNYNEN, Kullervo , CLEMENT, Gregory, T.
发明人： HYNYNEN, Kullervo , CLEMENT, Gregory, T.
IPC分类号： A61N7/00
CPC分类号： A61B8/54 , A61B8/0808 , A61B8/485 , A61B17/22004 , A61N7/00 , A61N2007/0078
摘要： A method of delivering ultrasound signals using shear waves includes applying a portion of at least a first ultrasound beam to a subject at at least a first incident angle relative to the surface of the subject to induce shear waves in the subject, energy in the shear waves forming a substantial part of energy of first ultrasound waves at a desired region in the subject at a therapeutic level.
摘要翻译：使用剪切波输送超声信号的方法包括：至少第一超声波束的一部分相对于受试者的表面以至少第一入射角施加到受试者，以在受试者中引起剪切波，剪切波中的能量在治疗水平上在受治疗者的期望区域形成第一超声波的大部分能量。

3. 发明申请

WO2003017843A1 ULTRASOUND THERAPY 审中-公开
标题翻译：超声疗法
公开(公告)号：WO2003017843A1
公开(公告)日：2003-03-06
申请号：PCT/US2002/027130
申请日：2002-08-26
申请人： THE BRIGHAM AND WOMEN'S HOSPITAL, INC. , HYNYNEN, Kullervo , CLEMENT, Gregory, T.
发明人： HYNYNEN, Kullervo , CLEMENT, Gregory, T.
IPC分类号： A61B8/00
CPC分类号： A61N7/02 , A61B8/0808 , A61B8/0858 , A61N2007/0095
摘要： A way of delivering ultrasound signals includes providing an image of at least a portion of a subject (30) intended to receive ultrasound signals between sources of the ultrasound signals and a desired region of the subject (3) for receiving focused ultrasound signals, identifying, from the image, physical characteristics of portions of material between the sources and the desired region, and using a spectral propagation analysis to determine at least one of phase corrections and amplitude corrections for the sources depending on the respective physical characteristics of the portions of the material disposed between each source and the desired region.
摘要翻译：传送超声信号的一种方式包括提供目标物（30）的至少一部分的图像，其目的是在超声信号的源和受检者（3）的所需区域之间接收超声信号，用于接收聚焦超声信号，根据图像，来自源和期望区域之间的材料部分的物理特性，以及使用光谱传播分析来确定源的相位校正和振幅校正中的至少一个，这取决于材料部分的相应物理特性设置在每个源和期望的区域之间。

4. 发明申请

WO2005019984A2 SUPERRESOLUTION ULTRASOUND 审中-公开
标题翻译：超级超声波
公开(公告)号：WO2005019984A2
公开(公告)日：2005-03-03
申请号：PCT/US2004/025077
申请日：2004-08-04
申请人： BRIGHAM & WOMEN'S HOSPITAL, INC. , CLEMENT, Gregory, T. , HYNYNEN, Kullvero, H.
发明人： CLEMENT, Gregory, T. , HYNYNEN, Kullvero, H.
IPC分类号： G06F
CPC分类号： A61B8/08 , A61B8/06 , A61B8/0825
摘要： A computer program product resides on a computer-readable medium and comprises computer-readable, computer-executable instructions for causing a computer to transmit first indicia for an ultrasound propagation arrangement to propagate ultrasound energy toward a focal region containing an object, receive second indicia from a receiver positioned to receive the propagated ultrasound energy after passing at least one of by and through the object and configured to transduce the received ultrasound energy into the second indicia, analyze the second indicia to determine magnitude and phase of the received ultrasound energy, and use the determined magnitude and phase of the received ultrasound energy and knowledge of the ultrasound energy propagated from the propagation arrangement to mathematically propagate indicia of at least one of the received ultrasound energy and the transmitted ultrasound energy to a common location.
摘要翻译：计算机程序产品驻留在计算机可读介质上，并且包括计算机可读的计算机可执行指令，用于使计算机传送超声波传播装置的第一标记以向包含对象的聚焦区域传播超声能量，从第接收器，定位成在通过并通过对象中的至少一个并且被配置为将所接收的超声能量转换成第二标记以接收传播的超声能量，分析第二标记以确定所接收的超声能量的大小和相位，并使用接收的超声能量的确定的幅度和相位以及从传播装置传播的超声能量的知识将数学上将所接收的超声能量和所发送的超声能量中的至少一个的标记传播到公共位置。

5. 发明申请

WO2007051075A1 ULTRASOUND IMAGING 审中-公开
标题翻译：超声成像
公开(公告)号：WO2007051075A1
公开(公告)日：2007-05-03
申请号：PCT/US2006/042608
申请日：2006-10-30
申请人： BRIGHAM AND WOMEN'S HOSPITAL, INC. , CLEMENT, Gregory, T.
发明人： CLEMENT, Gregory, T.
IPC分类号： G01S7/52 , G01S15/89 , G10K11/34
CPC分类号： G01S15/8977 , A61B8/13 , A61B8/54 , G01S7/5205 , G01S15/8954
摘要： An ultrasound imaging system for use in producing an image of an object in a region of interest includes: an exciter configured to provide an excitation signal; a transducer coupled to the exciter and configured to produce, in response to the excitation signal, an ultrasound field whose complex frequency content varies with field location; a receiver configured to receive ultrasound signals reflected by the object and to produce indicia of the received reflected ultrasound signals; and a processor coupled to the receiver and configured to cross-correlate the indicia of the received reflected ultrasound signals with indicia of the ultrasound field at pixels in the region of interest to determine image pixel intensities of the region of interest for producing an image.
摘要翻译：用于产生感兴趣区域中的物体的图像的超声成像系统包括：激励器，被配置为提供激励信号; 耦合到所述激励器并且被配置为响应于所述激励信号产生其复频率内容随着场位置而变化的超声场的换能器; 接收器，其被配置为接收由所述对象反射的超声信号并产生所接收的反射超声信号的标记; 以及处理器，其耦合到所述接收器并且被配置为将所接收的反射的超声信号的标记与所述感兴趣区域中的像素处的所述超声波的标记进行交叉相关，以确定用于产生图像的所述感兴趣区域的图像像素强度。

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