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    • 1. 发明申请
    • MODULATING BRAIN ACTIVITY DURING SLEEP
    • 调节睡眠期间的脑活动
    • WO2018053296A1
    • 2018-03-22
    • PCT/US2017/051826
    • 2017-09-15
    • TAL MEDICAL
    • MADDEN, MichaelSKVARKA, JanGODDARD, AlexBHARDWAJ, JasonPANDE, AtulSAWCHAK, SharonMILLER, Andrew
    • A61N2/00A61B5/0476A61N2/02A61B5/00
    • This disclosure relates to devices, methods and systems for the recording of electroencephalograph (EEG) signals and application of subthreshold magnetic stimulation (StMS) to modulate brain activity during sleep. Embodiments of the present disclosure provide devices, methods and systems that acquire an individual's EEG signal while simultaneously applying StMS to the individual during sleep, process the EEG signal such that electromagnetic transients associated with StMS are removed, analyze the signal to detect sleep stage, and control the application, waveform temporal parameters, strength, or other parameters of StMS based upon the detected sleep stage. The present disclosure is useful for research purposes, commercial applications and clinical interventions.
    • 本公开涉及用于记录脑电图(EEG)信号和应用亚阈值磁刺激(StMS)来调节睡眠期间的大脑活动的装置,方法和系统。 本公开的实施例提供了在睡眠期间同时将StMS应用于个体的同时获取个体的EEG信号的装置,方法和系统,处理EEG信号使得去除与StMS相关联的电磁瞬变,分析信号以检测睡眠阶段,并且 基于检测到的睡眠阶段来控制StMS的应用,波形时间参数,强度或其他参数。 本公开对于研究目的,商业应用和临床干预是有用的。