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1. 发明申请

WO2017021864A1 A PROCESS AND APPARATUS FOR CONTINUOUS GRANULATION OF POWDER MATERIAL 审中-公开
标题翻译：一种连续粉碎粉末材料的方法和装置
公开(公告)号：WO2017021864A1
公开(公告)日：2017-02-09
申请号：PCT/IB2016/054616
申请日：2016-08-01
申请人： STEERLIFE INDIA PRIVATE LIMITED
发明人： GHIKE,, Radhika , KULKARNI, Vijay , BHUSHAN, Indu , SEN, Himadri , PADMANABHAN, Babu , RAO, Vinay
IPC分类号： B29B7/48 , B29B7/50 , B29C47/40
CPC分类号： B29C47/40 , B01J2/20 , B29B9/06 , B29C47/0011 , B29C47/6056 , B29C47/6075 , B29C47/92 , B29C2947/926 , B29C2947/92723
摘要： The present disclosure relates to a process for preparing granules from an input material or a powder material. The process comprises feeding the input material for granulation in the processor using one or more powder feeders, introducing steam as a granulation activating agent in the processor, granulating the input material in presence of the steam to form granules, and optionally collecting the granules from a discharge zone of the processor, wherein feed rate of the steam into the processor is determined based on feed rate of the input material into the processor. A co-rotating twin-screw processor for preparing granules is also disclosed.
摘要翻译：本公开涉及从输入材料或粉末材料制备颗粒的方法。该方法包括使用一种或多种粉末进料器将用于造粒的输入材料进料进料，在处理器中引入蒸汽作为造粒活化剂，在蒸汽存在下造粒输入物质以形成颗粒，并任选地从处理器的排出区域，其中进入处理器的蒸汽的进料速率基于输入物料进入处理器的进给速率来确定。还公开了一种用于制备颗粒的同向旋转双螺杆处理器。

2. 发明申请

WO2017183006A1 A PROCESSOR AND A PROCESS FOR GRANULATION OF POWDERS 审中-公开
标题翻译：处理器和粉碎颗粒的方法
公开(公告)号：WO2017183006A1
公开(公告)日：2017-10-26
申请号：PCT/IB2017/052334
申请日：2017-04-24
申请人： STEERLIFE INDIA PRIVATE LIMITED
发明人： BHUSHAN, Indu , PADMANABHAN, Babu , RAO, Vinay , KULKARNI, Vijay , CHINCHOLI, Chetan , GHIKE, Radhika , GANESHAN, Raja
IPC分类号： B01F7/00 , B01F15/02 , B29B7/48 , B29C47/40 , B29C47/62 , C08J3/12
摘要： A fractional lobe processor is disclosed. The fractional lobe processor comprises an intake zone comprising at least one deep flighted shovel element on each intermeshing screw for receiving a input blend comprising an active substance and an excipient; a granulation zone consisting of only fractional lobe elements, and having a provision for introducing moisture or a binder solution, for granulating the active substance and the excipient; an optional, drying zone for drying the wet granules; and a discharge zone for discharging the granules; wherein the granulation zone is located before the discharge zone and after the intake zone; wherein the drying zone has one or more fractional lobe elements on each shaft; and wherein the granulation zone has a plurality of fractional lobe elements on each shaft.
摘要翻译：公开了一种分数波瓣处理器。分瓣处理器包括入口区域，所述入口区域包括在每个啮合螺杆上的至少一个深层铲单元，用于接收包含活性物质和赋形剂的输入混合物; 造粒区域，仅由分数叶片元件组成，并且具有用于引入水分或粘合剂溶液的装置，用于将活性物质和赋形剂造粒; 任选的用于干燥湿颗粒的干燥区; 和用于排出颗粒的排出区域; 其中造粒区位于排放区之前和进口区之后; 其中所述干燥区在每个轴上具有一个或多个分瓣部件; 并且其中造粒区在每个轴上具有多个分数波瓣元件。

3. 发明申请

WO2017060861A2 RAPIDLY DISINTEGRATING TABLET COMPOSITIONS OF DPP-IV INHIBITORS WITH LOW MINERAL CONTENT 审中-公开
标题翻译： DPP-IV抑制剂快速消毒低成本含量的片剂组合物
公开(公告)号：WO2017060861A2
公开(公告)日：2017-04-13
申请号：PCT/IB2016/056010
申请日：2016-10-07
申请人： STEERLIFE INDIA PRIVATE LIMITED
发明人： PADMANABHAN, Babu , SEN, Himadri , BHUSHAN, Indu , KULKARNI, Vijay , SHETTY, Rakshith , GURRAM, Aravind Kumar
IPC分类号： A61K31/519 , A61K9/20
CPC分类号： A61K9/20 , A61K31/40 , A61K31/403 , A61K31/4985 , A61K31/515 , A61K31/522
摘要： A rapidly disintegrating tablet comprising a therapeutically effective amount of a DPP- IV inhibitor and an acid-base couple having mineral content below the daily intake limits is disclosed. The rapidly disintegrating tablet has a sodium content less than 10 mg and a potassium content less than 15 mg. A process for preparation of the rapidly disintegrating tablet comprising the DPP-IV inhibitor is also disclosed.
摘要翻译：公开了包含治疗有效量的DPP-IV抑制剂和矿物质含量低于每日摄入限度的酸碱对的快速崩解片剂。快速崩解片剂的钠含量小于10mg，钾含量小于15mg。还公开了包含DPP-IV抑制剂的快速崩解片剂的制备方法。

4. 发明申请

WO2018167681A1 DOSER CAP FOR LIQUID CONTAINER 审中-公开
公开(公告)号：WO2018167681A1
公开(公告)日：2018-09-20
申请号：PCT/IB2018/051692
申请日：2018-03-14
申请人： STEERLIFE INDIA PRIVATE LIMITED
发明人： BANGERA, Subba , PADMANABHAN, Babu , BANGERA, Ravi , JAGTAP, Rohit , KULKARNI, Kaustubh
IPC分类号： B65D41/34 , B65D51/28
摘要： The present invention relates to doser cap for liquid containers. More particularly the present invention relates to doser cap for liquid containers, wherein the cap has storage chamber enclosing powder material or active substance that can be dispensed into the liquid container by rupturing the seal. The doser cap of the present invention comprises bottom cap, top cap, cutting unit, spiral cam slot, pushing rib, and entry groove on top cap.

5. 发明申请

WO2017183007A1 A FRACTIONAL LOBE PROCESSOR 审中-公开
标题翻译：分级的LOBE处理器
公开(公告)号：WO2017183007A1
公开(公告)日：2017-10-26
申请号：PCT/IB2017/052335
申请日：2017-04-24
申请人： STEERLIFE INDIA PRIVATE LIMITED
发明人： BHUSHAN, Indu , RAO, Vinay , KULKARNI, Vijay , CHINCHOLI, Chetan , GURRAM, Aravind Kumar , PADMANABHAN, Babu
IPC分类号： B29C47/62 , B29C47/40 , B29C47/66 , B29C47/88 , B29B7/48 , A61K9/14 , A61K9/20
摘要： A fractional lobe processor is disclosed. The fractional lobe processor comprises: a barrel with heating and cooling means having two parallel intersecting bores of equal diameter, wherein the centre distance between the two bores is lesser than the diameter of the bore; a shaft coupled with a plurality of screw elements to form a screw within each bore, wherein the screws are intermeshing, and wherein the screws form at least three zones within the barrel, the zones comprising an intake zone comprising at least one deep flighted shovel element on each intermeshing screw for receiving a feed comprising an active substance and/or an excipient, a melt zone consisting of only fractional lobe elements for melting the active substance and/or an excipient to form a viscous mass or melt, and a discharge zone, wherein the melt zone is located before the discharge zone and after the intake zone; and wherein the melt zone has a plurality of fractional lobe elements on each shaft.
摘要翻译：公开了一种分数波瓣处理器。分瓣处理器包括：具有加热和冷却装置的筒体，所述加热和冷却装置具有两个相等直径的平行相交孔，其中两个孔之间的中心距小于孔的直径; 与多个螺杆元件联接以在每个孔内形成螺杆的轴，其中所述螺杆相互啮合，并且其中所述螺杆在所述筒内形成至少三个区域，所述区域包括入口区域，所述入口区域包括至少一个深层刮铲元件在用于接收包含活性物质和/或赋形剂的进料的每个啮合螺杆上，由仅用于熔化活性物质和/或赋形剂以形成粘性物质或熔体的分数叶片元件组成的熔融区和排出区，其中所述熔化区位于所述排出区之前和所述进入区之后; 并且其中熔融区在每个轴上具有多个分数波瓣元件。

6. 发明申请

WO2022013763A1 CONTINUOUS GRANULATION SYSTEM AND METHOD FOR OBTAINING CONDITIONED GRANULES 审中-公开
公开(公告)号：WO2022013763A1
公开(公告)日：2022-01-20
申请号：PCT/IB2021/056327
申请日：2021-07-14
申请人： STEERLIFE INDIA PRIVATE LIMITED
发明人： PADMANABHAN, Babu , BHUSHAN, Indu , RAO, Vinay
IPC分类号： B01J2/16 , B01J2/00 , B01J2/20 , B29B9/00 , B29B9/02 , B29B9/16
摘要： A continuous granulation system for obtaining conditioned granules is disclosed. The system comprises a processor configured to produce a continuous flow of granules at an outlet of the processor. The system also comprises a collection chamber positioned downstream from the processor and configured to collect the granules from the outlet. Further, the system comprises an air displacement device coupled to the collection chamber and configured to create a unidirectional flow of air at the outlet in a direction of the granules exiting the processor and away from the outlet. The unidirectional flow of air conditions the granules obtained in the collection chamber. A continuous granulation method and a continuous granule collection system for obtaining the conditioned granules is also disclosed.

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