专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2005063768A1 NOVEL PYRIDINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME 审中-公开
标题翻译：新型吡啶衍生物，其制备方法和含有其的药物组合物
公开(公告)号：WO2005063768A1
公开(公告)日：2005-07-14
申请号：PCT/KR2004/003545
申请日：2004-12-30
申请人： SK CHEMICALS, CO., LTD. , KIM, Hyung Ook , LEE, Nam Kyu , KIM, Joo Hyon , RHEE, Hae In , CHO, Yong-Baik , RYU, Je Ho , KIM, Nam ho , RYU, Keun Ho , YI, Jung Bum , JUNG, Jae Yoon
发明人： KIM, Hyung Ook , LEE, Nam Kyu , KIM, Joo Hyon , RHEE, Hae In , CHO, Yong-Baik , RYU, Je Ho , KIM, Nam ho , RYU, Keun Ho , YI, Jung Bum , JUNG, Jae Yoon
IPC分类号： C07D491/052
CPC分类号： C07D471/04 , C07D491/052
摘要： This invention relates to novel pyridine derivatives having an inhibitory effect on production of cytokines, which are involved in inflammatory responses, thus suggesting its usefulness as therapeutic agents for treating diseases related to inflammation, immune, chronic inflammation as well as an agent having an anti-inflammatory and analgesic effect. Further, this invention relates to a method of manufacturing the same and a pharmaceutical composition containing the same.
摘要翻译：本发明涉及具有抑制细胞因子产生抑制作用的吡啶衍生物，其涉及炎性反应，因此表明其作为用于治疗与炎症，免疫，慢性炎症有关的疾病的治疗剂以及具有抗炎作用的药物的有用性，炎症和镇痛作用。此外，本发明涉及其制造方法和含有该组合物的药物组合物。

2. 发明申请

WO2005042485A1 ACID ADDED SALTS OF AMLODIPINE 审中-公开
标题翻译：酸添加的AMLODIPINE的盐
公开(公告)号：WO2005042485A1
公开(公告)日：2005-05-12
申请号：PCT/KR2004/002756
申请日：2004-10-29
申请人： SK CHEMICALS, CO., LTD. , KIM, Jae-Sun , CHOI, Jin Young , RYU, Je Ho , KIM, Nam ho , LEE, Nam Kyu , OH, Yong Ho , OH, Joon-Gyo , JANG, Woo Jae , KUM, Do Seung , UM, Key An , KWAK, Wie-Jong
发明人： KIM, Jae-Sun , CHOI, Jin Young , RYU, Je Ho , KIM, Nam ho , LEE, Nam Kyu , OH, Yong Ho , OH, Joon-Gyo , JANG, Woo Jae , KUM, Do Seung , UM, Key An , KWAK, Wie-Jong
IPC分类号： C07D211/90
CPC分类号： C07D211/90
摘要： The present invention relates to crystalline acid salts of amlodipine which exhibit excellent physicochemical properties such as high aqueous solubility, stability, non-hygroscopicity and anti-stiction property, thereby providing an effective therapeutic agent in the treatment of cardiovascular diseases including hypertension.
摘要翻译：本发明涉及氨氯地平的结晶酸盐，其具有优异的物理化学性质，例如高溶解性，稳定性，非吸湿性和抗静电性，从而提供治疗包括高血压在内的心血管疾病的有效治疗剂。

3. 发明申请

WO2009145368A1 IMPROVED PREPARING METHOD OF (S)-OMEPRAZOLE FROM OMEPRAZOLE RACEMATE USING OPTICAL RESOLUTION AGENT 审中-公开
标题翻译：使用光学分解剂改进从奥美拉唑的（S） - 甲基吡咯的制备方法
公开(公告)号：WO2009145368A1
公开(公告)日：2009-12-03
申请号：PCT/KR2008/002961
申请日：2008-05-27
申请人： SK CHEMICALS CO., LTD. , KIM, Jae-Sun , LEE, Jin Young , KIM, Sun Ho , KIM, Nam ho , LEE, Nam Kyu , PARK, Eun Ju , KUM, Do Seung
发明人： KIM, Jae-Sun , LEE, Jin Young , KIM, Sun Ho , KIM, Nam ho , LEE, Nam Kyu , PARK, Eun Ju , KUM, Do Seung
IPC分类号： C07D401/12 , C07D277/30 , A61K31/415 , A61K31/44
CPC分类号： C07D401/12
摘要： The present invention relates to an improved preparing method of ( S )-omeprazole from omeprazole racemate. In an exemplary embodiment, the preparing method according to the present invention comprises the steps of: a) reacting omeprazole racemate with optically active diethyl-D-tartrate and a titanium compound in an alcohol solvent to prepare an omeprazole racemic complex; b) reacting the omeprazole racemic complex with 1.5-3.0 molar equivalents of ( S )-(+)-mandelic acid as optical resolution agent to prepare an optically active ( S )-omeprazole complex; and c) dissociating the optically active ( S) -omeprazole complex with a basic solution to prepare an ( S )-omeprazole free base or reacting the ( S )- omeprazole free base with a metal salt to transfer to a metal salt or a metal salt hydrate of ( S )- omeprazole. With optical purity of 99.0 %ee or better, the ( S )-omeprazole, the metal salt thereof or the hydrate thereof prepared in accordance with the present invention is useful as a medicinal material.
摘要翻译：本发明涉及一种改善奥美拉唑外消旋物（S） - 奥美拉唑的制备方法。在一个示例性实施方案中，根据本发明的制备方法包括以下步骤：a）使奥美拉唑外消旋物与光学活性的D-酒石酸二乙酯和钛化合物在醇溶剂中反应以制备奥美拉唑外消旋体; b）将奥美拉唑外消旋配合物与1.5-3.0摩尔当量的（S） - （+） - 扁桃酸作为光学拆分剂反应，制备光学活性（S） - 奥美拉唑复合物; 和c）用碱性溶液解离光学活性（S） - 奥美拉唑复合物以制备（S） - 奥美拉唑游离碱或使（S） - 奥美拉唑游离碱与金属盐反应转移至金属盐或金属（S） - 奥美拉唑盐水合物。光学纯度为99.0％ee或更好，根据本发明制备的（S） - 奥美拉唑，其金属盐或其水合物可用作药用材料。

4. 发明申请

WO2007142416A1 HEADGEAR CAPABLE OF BEING ATTACHED AND SEPARATED ORNAMENTS 审中-公开
标题翻译：可连接和分离的组件的头盔
公开(公告)号：WO2007142416A1
公开(公告)日：2007-12-13
申请号：PCT/KR2007/002453
申请日：2007-05-21
申请人： LEE, Seung hoon , KIM, Nam ho
发明人： LEE, Seung hoon , KIM, Nam ho
IPC分类号： A42B1/24
CPC分类号： A42B1/24 , A41G5/0093
摘要： The present invention relates to a headgear which provides not only the protective function of protecting a head of a wearer or shading the direct rays of the sun, but also the decorative function by attaching accessories. For a headgear having a visor for shading a sunlight and a cap for fixing the visor to a head, a hole is formed in one side of the cap and an engaging part is disposed in the hole. For a headgear having a visor for shading a sunlight, a cap for fixing the visor to a head, and a lining provided inside the cap for protecting the head from external impact and preventing marking on a forehead, an engaging part is formed between the lining and the cap.
摘要翻译：本发明涉及一种头盔，其不仅提供保护佩戴者头部或遮蔽太阳直射线的保护功能，而且还提供附件附件的装饰功能。对于具有用于遮蔽阳光的遮阳板和用于将遮阳板固定到头部上的帽子的头饰，在盖的一侧形成有孔，并且接合部设置在孔中。对于具有用于遮蔽阳光的遮阳板的头饰，用于将遮阳板固定在头部上的帽子以及设置在帽内的衬里，用于保护头部免受外部冲击并防止在前额上的标记，在衬垫之间形成接合部分和帽子。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式