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1. 发明申请

WO2004075796A1 DELIVERING COOLED FLUID TO SITES INSIDE THE BODY 审中-公开
标题翻译：将冷却的液体输送到身体内的站点
公开(公告)号：WO2004075796A1
公开(公告)日：2004-09-10
申请号：PCT/US2003/041153
申请日：2003-12-23
申请人： SCIMED LIFE SYSTEMS, INC.
发明人： DRASLER, William, J. , HARRISON, Kent , JENSON, Mark, L. , KOKATE, Jaydeep, Y. , RICHARDSON, Leonard, B.
IPC分类号： A61F7/12
CPC分类号： A61M25/104 , A61B2017/22001 , A61F7/12 , A61F2007/0075 , A61F2007/126 , A61M1/3613
摘要： Devices and methods to deliver cooled fluid to an internal site in the body are disclosed. A catheter for infusing a fluid to a site internal to the body includes an elongated member (22) having a distal end (34) positionable to be near the internal site and a lumen extending longitudinally through the member to the distal end of the member. An element (26) cools fluid as it flows through the lumen before the fluid exits the lumen at the distal end. A method of performing an interventional procedure includes inserting a guide catheter into an aorta and seating a distal end of the guide catheter in a coronary ostium. A lesion is treated to eliminate an impediment to blood flow through a vessel, the treatment permitting increased blood flow through the vessel. Cooled fluid is provided to the ischemic tissue region caused by the lesion.
摘要翻译：公开了将冷却流体输送到身体内部部位的装置和方法。用于将流体注入到身体内部的位置的导管包括具有可定位成靠近内部位置的远端（34）的细长构件（22），以及沿构件纵向延伸穿过构件到远端的内腔。当流体在远端处离开内腔时，元件（26）在液体流过管腔时冷却流体。执行介入手术的方法包括将引导导管插入主动脉并且将导向导管的远端安置在冠状口中。治疗病变以消除通过血管的血液流动的障碍，该治疗允许增加通过血管的血流量。将冷却的液体提供给由病变引起的缺血组织区域。

2. 发明申请

WO2004037128A1 VENOUS VALVE APPARATUS AND METHOD 审中-公开
标题翻译： VENOUS阀门装置和方法
公开(公告)号：WO2004037128A1
公开(公告)日：2004-05-06
申请号：PCT/US2003/033521
申请日：2003-10-23
申请人： SCIMED LIFE SYSTEMS, INC.
发明人： DRASLER, William, J. , JENSON, Mark, L.
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2/2475 , A61F2220/0016 , A61F2220/005
摘要： Embodiments of the invention provide for a unidirectional flow valve. For example, embodiments of the invention include a method of providing a unidirectional flow valve to a vein that include folding a first portion of a vein over an adjacent second portion of a vein and engaging at least two opposing areas of the second portion of the vein to adjacent areas of the first portion of the vein. The at least two opposing walls of the second portion of the vein define the unidirectional flow valve. At least one support device may be inserted into the forded valve region of the vein to maintain the folded configuration of the valve.
摘要翻译：本发明的实施例提供了一种单向流量阀。例如，本发明的实施例包括向静脉提供单向流量阀的方法，其包括在静脉的相邻第二部分上折叠静脉的第一部分并且接合静脉的第二部分的至少两个相对的区域到静脉的第一部分的相邻区域。静脉的第二部分的至少两个相对的壁限定单向流量阀。至少一个支撑装置可以插入到静脉的插入阀区域中以保持阀的折叠构型。

3. 发明申请

WO2004075747A1 DELIVERING COOLED FLUID TO SITES INSIDE THE BODY 审中-公开
标题翻译：将冷却的流体输送到身体内的场所
公开(公告)号：WO2004075747A1
公开(公告)日：2004-09-10
申请号：PCT/US2003/041171
申请日：2003-12-23
申请人： SCIMED LIFE SYSTEMS, INC.
发明人： HARRISON, Kent , JENSON, Mark, L. , KOKATE, Jaydeep, Y. , DRASLER, William, J. , RICHARDSON, Leonard, B.
IPC分类号： A61B5/028
CPC分类号： A61F7/12 , A61B5/028 , A61F2007/126 , A61M2205/3368
摘要： Devices and methods to deliver cooled fluid to an internal site in the body are disclosed. A catheter includes an elongated member having a lumen longitudinally extending therethrough to a distal end of the elongated member. A temperature sensor senses the temperature of the fluid flowing through the lumen near the distal end. One method for treating an ischemic tissue region before reperfusion includes inserting a balloon catheter into a coronary vein that provides access to the ischemic tissue region. The balloon is inflated to occlude the coronary vein and cooled fluid is delivered from the balloon catheter and distal to the balloon. Another method involves inserting a catheter into a coronary artery where a lesion is obstructing blood flow through the artery. The distal end of the catheter is positioned at a location distal to the lesion and cooled fluid is provided from the distal end of the catheter.
摘要翻译：公开了将冷却流体输送到身体内部部位的装置和方法。导管包括细长构件，其具有纵向延伸穿过其延伸到细长构件的远端的内腔。温度传感器检测在远端附近流过管腔的流体的温度。在再灌注之前治疗缺血组织区域的一种方法包括将气囊导管插入提供对缺血组织区域的通路的冠状静脉。气球膨胀以封闭冠状静脉，并且冷却的流体从气囊导管输送并远离气囊。另一种方法是将导管插入冠状动脉，其中病变阻塞血液通过动脉。导管的远端定位在远离损伤处的位置处，并且从导管的远端提供冷却的流体。

4. 发明申请

WO2004032805A1 EMBOLIC ENTRAPMENT SHEATH 审中-公开
公开(公告)号：WO2004032805A1
公开(公告)日：2004-04-22
申请号：PCT/US2003/032386
申请日：2003-10-10
申请人： SCIMED LIFE SYSTEMS, INC.
发明人： DRASLER, William J. , JENSON, Mark, L.
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/01 , A61F2/89 , A61F2002/018 , A61F2230/0006 , A61F2230/0069 , A61F2230/0078 , A61F2250/0063
摘要： An embolic entrapment device and system (10) comprises a flexible polymeric sheath (12) and an expansion member (22) engaged to each end of the sheath. The device is used in a method of treating a lesion by placing the device across the lesion and expanding the device.
摘要翻译：栓塞装置和系统（10）包括柔性聚合物护套（12）和与护套的每个端部接合的扩张构件（22）。该装置用于通过将装置放置在病变上并扩大装置来治疗病变的方法。

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