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1. 发明申请

WO2017129206A1 MIXING IMPELLER, METHOD OF MANUFACTURING A FIRST SUBASSEMBLY OF THE MIXING IMPELLER AND METHOD OF ASSEMBLING THE MIXING IMPELLER 审中-公开
标题翻译：混合叶轮，制造混合叶轮的第一次组合体的方法以及组装混合叶轮的方法
公开(公告)号：WO2017129206A1
公开(公告)日：2017-08-03
申请号：PCT/EP2016/002004
申请日：2016-11-28
申请人： SARTORIUS STEDIM BIOTECH GMBH , SARTORIUS STEDIM NORTH AMERICA INC. , SARTORIUS STEDIM SWITZERLAND AG , SARTORIUS STEDIM LAB LTD.
发明人： OSCHWALD, Martin , CUTTING, Jonathan E. , BÖTTCHER, Lars , WEST, Sharon D. , BATES, Mike
IPC分类号： B01F13/08 , B01F15/00 , B29D99/00 , B29C45/14
CPC分类号： B01F7/00341 , B01F7/0025 , B01F13/0827 , B01F15/0085 , B01F15/00935 , B29C45/1418 , B29C45/14778 , B29C45/14819 , B29C45/1671 , B29D99/0082 , B29K2995/0008
摘要： The present application relates to a mixing impeller (1) comprising: - a first subassembly (3) in which at least one magnet (11) is accommodated, wherein the magnet (11) is adapted to be magnetically coupled to a drive device to be driven; and - a second subassembly (3, 5) comprising at least one impeller blade for mixing components when rotating the mixing impeller (1); wherein the first and second subassemblies (3, 5) are formed as separate entities which are selectively engageable. Further, the present invention relates to a method of manufacturing the first subassembly (3) and a method of assembling the mixing impeller (1).
摘要翻译：本发明涉及一种混合叶轮（1），该混合叶轮（1）包括：第一子组件（3），其中容纳有至少一个磁体（11），其中磁体（11）适于磁耦合到待驱动的驱动装置; 以及 - 第二子组件（3,5），其包括用于在旋转所述混合叶轮（1）时混合组分的至少一个叶轮叶片; 其中第一和第二子组件（3,5）形成为可选择性地接合的独立实体。此外，本发明涉及制造第一子组件（3）的方法和组装混合叶轮（1）的方法。

2. 发明申请

WO2017129204A1 MIXING VESSEL WITH LOCKING ASSEMBLY FOR LOCKING A MIXING ASSEMBLY IN STORAGE POSITION AND MIXING IMPELLER WITH CENTRAL DISC-LIKE MEMBER 审中-公开
标题翻译：带有锁定组件的混合容器，用于将混合组件锁定在存储位置并将混合叶轮与中央圆盘状构件
公开(公告)号：WO2017129204A1
公开(公告)日：2017-08-03
申请号：PCT/EP2016/002002
申请日：2016-11-28
申请人： SARTORIUS STEDIM BIOTECH GMBH , SARTORIUS STEDIM NORTH AMERICA INC. , SARTORIUS STEDIM SWITZERLAND AG , SARTORIUS STEDIM LAB LTD.
发明人： OSCHWALD, Martin , CUTTING, Jonathan E. , BÖTTCHER, Lars , WEST, Sharon D. , BATES, Mike
IPC分类号： B01F13/08 , B01F15/00
CPC分类号： B01F7/00208 , B01F7/00341 , B01F7/22 , B01F13/0827 , B01F15/00662 , B01F15/0085 , B01F15/00876
摘要： The present application relates to a mixing vessel (100) for accommodating components to be mixed, comprising: - a container, which has at least one mounting depression (102) in a side wall of the container, wherein the mounting depression (102) is adapted such that a mixing impeller housing (39, 7) of a mixing impeller (1, 7) is at least partly insertable, in which at least one magnet (11) is housed for being magnetically connectable to a drive device to be driven; and - a locking assembly being attachable to the mounting depression (102) from outside for locking the mixing impeller (1, 7) in a storage position, in which the mixing impeller (1, 7) is not rotatable, wherein the locking assembly comprises a magnetically active element (41), which is adapted to interact with the at least one magnet (11) of the mixing impeller (1, 7).Further, the present invention relates to a system comprising the mixing vessel (100) and at least one mixing impeller (1, 7), to a method of assembling, and to a mixing impeller (1, 7) for mixing components in a single-use mixing vessel (100).
摘要翻译：本申请涉及一种用于容纳待混合部件的混合容器（100），包括：容器，其在容器的侧壁中具有至少一个安装凹陷（102）其特征在于，所述安装凹陷（102）适于使得混合叶轮（1,7）的混合叶轮壳体（39,7）至少部分地可插入，其中容纳有至少一个磁体（11）以便可磁连接连接到要被驱动的驱动装置; 以及 - 锁定组件，所述锁定组件可从外部附接到所述安装凹陷部（102），以将所述混合叶轮（1,7）锁定在所述混合叶轮（1,7）不可旋转的存储位置中，其中所述锁定组件包括 - 适于与混合叶轮（1,7）的至少一个磁体（11）相互作用的磁活性元件（41）。另外，本发明涉及一种包括混合容器（100）和至少一个混合叶轮（1,7），组装方法以及用于在单次使用的混合容器（100）中混合组分的混合叶轮（1,7）。

3. 发明申请

WO2017129205A1 METHODS OF MIXING IMPELLER SENSING 审中-公开
标题翻译：混合叶轮传感方法
公开(公告)号：WO2017129205A1
公开(公告)日：2017-08-03
申请号：PCT/EP2016/002003
申请日：2016-11-28
申请人： SARTORIUS STEDIM BIOTECH GMBH , SARTORIUS STEDIM NORTH AMERICA INC. , SARTORIUS STEDIM SWITZERLAND AG
发明人： WEST, Sharon D. , OSCHWALD, Martin , CUTTING, Jonathan E. , BÖTTCHER, Lars
IPC分类号： G01N11/14 , B01F7/18 , C12M1/02
CPC分类号： B01F15/00285 , B01F3/1221 , B01F13/0818 , B01F15/00201 , B01F15/00233 , B01F15/00246 , B01F15/00389 , B01F2215/0032 , B01F2215/0409 , G01N11/14 , G01N2001/386 , G01N2011/0006 , G01N2011/0026 , G01N2011/0053
摘要： The present invention relates to a method of monitoring a flow behaviour of mixed components, comprising: rotating a mixing impeller at a first speed N 1 in a mixing vessel accommodating the components to be mixed; determining a first quantity (formula I) at the first speed N 1 , wherein N 1 is the speed at which the mixing impeller rotates and P 1 is the power required to rotate the mixing impeller at the first speed N 1 ; decreasing the speed of the mixing impeller to a speed N 2 ; determining a second quantity (formula II) at the second speed N 2 , wherein N 2 is the speed at which the mixing impeller rotates and P 2 is the power required to rotate the mixing impeller at the second speed N 2 ; comparing the first quantity (formula I) and the second quantity (formula II) and detecting whether the difference between the first and second quantities is within a specified range to determine whether the flow of the components in the mixing vessel is a turbulent flow; determining the density ρ of the mixed components based on at least one speed N i for which the flow is determined to be turbulent by the formula (III) wherein ρ is the density, P i is the power required to turn the mixing impeller at the speed N i , N P,constant is the Power number for a used mixing system configuration, N i is the speed at which the mixing impeller rotates and D is the diameter of the mixing impeller; further decreasing the speed of the mixing impeller; determining the Power number N P,variable for at least one detected speed N j at which the flow is determined to be non-turbulent by the formula (IV) wherein P j is the power required to rotate the mixing impeller at the speed N j , ρ is the density previously determined based on N P,constant, N j is the speed at which the mixing impeller rotates, and D is the diameter of the mixing impeller; and determining the dynamic viscosity μ of the mixed components by the formula (V) wherein ρ is the calculated density, N j is the speed at which the mixing impeller rotates, D is the diameter of the mixing impeller, P j is the power required to rotate the mixing impeller at the speed N j and x T corresponds to a specified relationship between the Reynolds number for the used mixing system configuration and the determined Power number N P,variable . Further, the present invention relates to methods for detecting settled solids at a mixing impeller.
摘要翻译：本发明涉及一种监测混合部件的流动行为的方法，包括：在混合容器中以第一速度N 1旋转混合叶轮，混合容器容纳组分混合; 在第一速度N 1下确定第一量（式I），其中N 1是混合叶轮旋转的速度，并且P 1 >是以第一速度N 1旋转搅拌叶轮所需的动力; 将搅拌叶轮的速度降低到N 2 / N; 在第二速度N 2下确定第二量（式II），其中N 2是混合叶轮旋转的速度，并且P 2 >是以第二速度N 2旋转搅拌叶轮所需的动力; 比较第一数量（公式I）和第二数量（公式II），并检测第一和第二数量之间的差异是否在指定的范围内以确定混合容器中的组分的流动是否是湍流; 基于至少一个速度N i，确定混合成分的密度ρ，通过公式（III）确定流动为湍流，其中ρ 是密度，P i是以速度N i，N P，恒定速度旋转混合叶轮所需的功率，是用过的混合系统配置的功率数量，N i是混合叶轮旋转的速度，D是混合叶轮的直径; 进一步降低混合叶轮的速度; 对于通过公式（IV）确定流量为非湍流的至少一个检测速度N determining确定功率数量N，变量，其中P < 是以速度N j旋转搅拌叶轮所需的功率，ρi是基于N P预先确定的密度，常数，Nj是搅拌叶轮旋转的速度，D是搅拌叶轮的直径; 并通过公式（V）确定混合组分的动态粘度μ，其中ρ是计算的密度，N j是在其中混合叶轮旋转，D是混合叶轮的直径，P j是使混合叶轮以速度N j和x n旋转所需的功率， T 对应于所使用的混合系统配置的雷诺数与确定的功率数量N <变量之间的指定关系。此外，本发明涉及用于检测混合叶轮处的沉降固体的方法。

4. 发明申请

WO2017129203A1 SYSTEM AND METHOD FOR RECEIVING A SINGLE-USE VESSEL 审中-公开
标题翻译：用于接收一次性容器的系统和方法
公开(公告)号：WO2017129203A1
公开(公告)日：2017-08-03
申请号：PCT/EP2016/002001
申请日：2016-11-28
申请人： SARTORIUS STEDIM BIOTECH GMBH , SARTORIUS STEDIM NORTH AMERICA INC. , SARTORIUS STEDIM SWITZERLAND AG
发明人： WEST, Sharon D. , OSCHWALD, Martin , CUTTING, Jonathan E. , BÖTTCHER, Lars
IPC分类号： B01F7/16 , B01F13/00 , B01F15/00
CPC分类号： B01F15/00318 , B01F7/162 , B01F7/163 , B01F7/1695 , B01F7/22 , B01F13/004 , B01F13/0042 , B01F15/0085 , B01F15/00857 , B01F2015/00584 , B01F2015/00597 , B01F2215/0073 , B65D25/205 , C12M23/14 , C12M23/26 , C12M23/28 , C12M27/02 , G06K7/10366
摘要： A System for receiving a single-use vessel containing a mixing device comprises a support structure adapted to receive the single-use vessel and a drive-unit adapted to power, to control, or to power and control a mixing of contents of the single-use vessel when the single-use vessel is arranged in the support structure. Therein, the support structure and the drive-unit are provided as separate components that may be arranged both in an operating position, wherein the drive-unit is connectable to the mixing device of the single-use bag in the support structure, and in a separated position, wherein the drive-unit is separated from the support structure. The drive-unit comprises a tag reader that, in the operating position, is arranged to read a vessel tag of the single-use vessel arranged in the support structure.
摘要翻译：用于接收含有混合装置的一次性容器的系统包括适于接收一次性容器的支撑结构和适于驱动，控制或驱动和控制一次性容器的驱动单元当一次性容器布置在支撑结构中时，一次性容器的内容物的混合。其中，支撑结构和驱动单元设置为分离的部件，其可以布置在操作位置，其中驱动单元可连接到支撑结构中的一次性袋的混合装置，并且在其中驱动单元与支撑结构分离。驱动单元包括标签读取器，该标签读取器在操作位置被布置为读取布置在支撑结构中的一次性容器的标签。

5. 发明申请

WO2017129207A1 MIXING METHODS 审中-公开
标题翻译：混合方法
公开(公告)号：WO2017129207A1
公开(公告)日：2017-08-03
申请号：PCT/EP2016/002008
申请日：2016-11-28
申请人： SARTORIUS STEDIM BIOTECH GMBH , SARTORIUS STEDIM NORTH AMERICA INC. , SARTORIUS STEDIM SWITZERLAND AG
发明人： WEST, Sharon, D. , OSCHWALD, Martin , CUTTING, Jonathan, E. , BÖTTCHER, Lars
IPC分类号： B01F15/00 , B01F7/00
CPC分类号： B01F15/00389 , B01F3/1221 , B01F7/00383 , B01F15/00201 , B01F2003/125 , B01F2015/00636 , B01F2015/00642
摘要： The present invention refers to a mixing method, a controller and a mixing device for mixing components in a mixing vessel, comprising: - providing a mixing impeller in the mixing vessel; - accelerating the mixing impeller from an inactive state to a rotating state in which the mixing impeller rotates at a first desired speed 10 in a first rotation direction; - rotating the mixing impeller at the first desired speed 10 for a first time t steady,1 in the first rotation direction; - changing the rotation direction of the mixing impeller, so that the mixing impeller rotates in a second rotation direction at a second desired speed 20; and - rotating the mixing impeller at the second desired speed for a second time t steady,2 .
摘要翻译：本发明涉及用于在混合容器中混合组分的混合方法，控制器和混合装置，其包括： - 在混合容器中提供混合叶轮; - 使混合叶轮从不活动状态加速到混合叶轮以第一期望速度10在第一旋转方向上旋转的旋转状态; - 使混合叶轮以第一期望速度10在第一旋转方向上第一时间t稳定1°旋转; - 改变混合叶轮的旋转方向，使得混合叶轮以第二期望速度20在第二旋转方向上旋转; 以及 - 以第二期望速度将搅拌叶轮以第二时间t稳定，2°旋转。

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