会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 1. 发明申请
    • AUTOMATIC GAIN CONTROL WITH DEFOCUSING LENS
    • 具有变焦镜头的自动增益控制
    • WO2014164198A1
    • 2014-10-09
    • PCT/US2014/021184
    • 2014-03-06
    • RAFFERTY, DavidSPENCER, MichaelWYLDE, JamesGARDNER, David, LorenzMINO, Warren
    • RAFFERTY, DavidSPENCER, MichaelWYLDE, JamesGARDNER, David, LorenzMINO, Warren
    • H01J49/14H01J49/42H01J49/06
    • H01J49/147H01J49/0013H01J49/0031H01J49/067H01J49/424H01J49/4265
    • In mass spectrometry, the number of ionized sample molecules affects various performance specifications of the resulting spectrum, including resolution, sensitivity, dynamic range, and scan speed. A voltage-controlled lens is used to control the number of electrons emitted from an electron source that enter the ion trap and ionize the target sample molecules. By monitoring a feature of the resulting spectrum, such as the resolution, total ion current, or a combination of these features, the lens voltage may be adjusted to create the optimal number of ions in the trap for a particular sample spectrum scan. Generally, for low concentration samples, the number of electrons introduced to the trap is increased, hence creating more ions in the trap, which in turn increases the intensity of the output signal improving the probability of detecting a sufficient number of ions by raising the intensity well above the noise floor. For higher concentration samples, the number of electrons is reduced, thus reducing interactions in the trap which in turn reduces peak broadening and improves resolution, as well as avoids saturating the detector. Several methods for adjusting the lens voltage may be used. First, the lens voltage may be repeatedly adjusted until the resulting spectrum reaches a desired trade-off between resolution and sensitivity. The Sens voltage may also be incrementally increased until the resulting spectrum begins to exhibit space charge effects. Finally, ail lens voltages in a list of usable voltage settings may be applied, and ail the resulting spectra are compared. The optimal voltage setting is selected and used for subsequent scans.
    • 在质谱中,电离样品分子的数量影响所得光谱的各种性能规格,包括分辨率,灵敏度,动态范围和扫描速度。 电压控制透镜用于控制从进入离子阱的电子源发射的电子数,并离子化目标样品分子。 通过监测所得光谱的特征,例如分辨率,总离子电流或这些特征的组合,可以调整透镜电压以在特定样品光谱扫描中产生陷阱中的最佳离子数。 通常,对于低浓度样品,引入陷阱的电子数量增加,从而在阱中产生更多的离子,这又增加了输出信号的强度,从而提高了通过提高强度来检测足够数量的离子的概率 远高于本底噪音。 对于较高浓度的样品,电子数量减少,从而减少陷阱中的相互作用,从而降低峰值变宽并提高分辨率,并避免检测器饱和。 可以使用用于调整透镜电压的几种方法。 首先,可以重复调整透镜电压,直到得到的光谱在分辨率和灵敏度之间达到期望的折衷。 Sens电压也可以递增地增加,直到得到的光谱开始显示空间电荷效应。 最后,可以应用可用电压设置列表中的ail透镜电压,并且比较所得到的光谱。 选择最佳电压设置并用于后续扫描。
    • 4. 发明申请
    • PRECONCENTRATING A SAMPLE
    • 预先采样样品
    • WO2011031559A1
    • 2011-03-17
    • PCT/US2010/047015
    • 2010-08-27
    • ASTROTECH CORPORATIONOJEDA, PedroRAFFERTY, DavidSPENCER, MichaelWYLDE, James
    • OJEDA, PedroRAFFERTY, DavidSPENCER, MichaelWYLDE, James
    • G01N1/40
    • H04R5/023A47C7/72G01N1/2214G01N1/40G01N1/405G01N27/622G01N33/0011G01N2001/022G01N2033/0019H01J49/26H04R2205/022Y10T436/255
    • A chemical analysis system is disclosed wherein, in evacuating a preconcentrator housing (2) prior to desorption, a pump system (13) reduces an internal pressure of the preconcentrator housing to a level substantially equal to an internal pressure of a chemical analyzer such that flow restrictors and/or membranes (15) between the chemical analyzer (7) and the preconcentrator housing (2) may be omitted. The chemical analysis system includes a chemical analyzer (7), a preconcentrator housing (2) coupled to the chemical analyzer, the preconcentrator housing enclosing a temperature control element (5, 18) and a sorbent material (1), the temperature control element configured to heat the sorbent material to adsorb or desorb a chemical of interest; and a pump system (13) coupled to the preconcentrator housing and the chemical analyzer, the pump system configured to evacuate the preconcentrator housing prior to desorption of the chemical of interest.
    • 公开了一种化学分析系统,其中在解吸之前抽空预浓缩器壳体(2)时,泵系统(13)将预浓缩器壳体的内部压力降低至基本等于化学分析器的内部压力的水平,使得流体 可以省略化学分析器(7)和预浓缩器壳体(2)之间的限制器和/或膜(15)。 化学分析系统包括化学分析器(7),耦合到化学分析器的预浓缩器壳体(2),包含温度控制元件(5,18)和吸附剂材料(1)的预浓缩器壳体,所述温度控制元件配置 加热吸附剂材料以吸附或解吸所关注的化学品; 以及耦合到所述预浓缩器壳体和所述化学分析器的泵系统(13),所述泵系统构造成在所述感兴趣的化学品的解吸附之前抽空所述预浓缩器壳体。