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1. 发明申请

WO2008020306A3 ISOINDOLE DERIVATIVES 审中-公开
公开(公告)号：WO2008020306A3
公开(公告)日：2008-02-21
申请号：PCT/IB2007/002469
申请日：2007-08-15
申请人： PFIZER PRODUCTS INC. , FAVOR, David, Alan , POWERS, James, Jeffrey , REPINE, Joseph, Thomas , WHITE, Andrew, David
发明人： FAVOR, David, Alan , POWERS, James, Jeffrey , REPINE, Joseph, Thomas , WHITE, Andrew, David
IPC分类号： A61K31/496 , A61K45/06 , C07D209/44 , C07D209/46 , C07D209/96 , C07D405/12 , C07D409/12 , A61P25/00
摘要： This invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, a process of making these compounds, pharmaceutical compositions containing one or more of these compounds or their salts, and their use for the treatment of schizophrenia, bipolar disorder, or other central nervous system disorders.

2. 发明申请

WO2006103559A1 TETRAHYDRO-PYRIDOAZEPIN-8-ONES AND RELATED COMPOUNDS FOR THE TREATMENT OF SCHIZOPHRENIA 审中-公开
标题翻译：四氢吡啶并嘧啶-8-酮及相关化合物治疗苦参碱
公开(公告)号：WO2006103559A1
公开(公告)日：2006-10-05
申请号：PCT/IB2006/000900
申请日：2006-03-20
申请人： WARNER-LAMBERT COMPANY LLC , FAVOR, David, Alan , JOHNSON, Douglas, Scott , REPINE, Joseph, Thomas , WHITE, Andrew, David
发明人： FAVOR, David, Alan , JOHNSON, Douglas, Scott , REPINE, Joseph, Thomas , WHITE, Andrew, David
IPC分类号： C07D471/04 , A61K31/55 , A61K31/551
CPC分类号： C07D471/04 , A61K31/55 , A61K31/5513
摘要： Compounds of formula 1 are disclosed, wherein G, D, A, Q, Y, Z, and R 1 through R 10 are defined in the specification. Also provided are descriptions of processes for preparing compounds of formula 1, intermediates used in making the same, and pharmaceutical compositions containing such compounds and their use in the treatment of central nervous system disorders and other disorders.
摘要翻译：公开了式1的化合物，其中在说明书中定义了G，D，A，Q，Y，Z和R 1至R 10。还提供了制备式1化合物的方法，用于制备式1的中间体和含有这些化合物的药物组合物及其在治疗中枢神经系统疾病和其它病症中的用途的描述。

3. 发明申请

WO2005019215A1 [1,8]NAPHTHYRIDIN-2-ONES AND RELATED COMPOUNDS FOR THE TREATMENT OF SCHIZOPHRENIA 审中-公开
标题翻译： [1,8]萘啶-2-酮及相关化合物治疗苦参碱
公开(公告)号：WO2005019215A1
公开(公告)日：2005-03-03
申请号：PCT/IB2004/002665
申请日：2004-08-13
申请人： WARNER-LAMBERT COMPANY LLC , CLARK, Jerry , DAVIS, Jamie , FAVOR, David , FAY, Lorraine , FRANKLIN, Lloyd , HENEGER, Kevin , JOHNSON, Douglas , NICHELSON, Brian , OU, Ligong , REPINE, Joseph, Thomas , WALTERS, Michael , WHITE, Andrew, David , ZHU, Zhijian
发明人： CLARK, Jerry , DAVIS, Jamie , FAVOR, David , FAY, Lorraine , FRANKLIN, Lloyd , HENEGER, Kevin , JOHNSON, Douglas , NICHELSON, Brian , OU, Ligong , REPINE, Joseph, Thomas , WALTERS, Michael , WHITE, Andrew, David , ZHU, Zhijian
IPC分类号： C07D471/04
CPC分类号： C07D471/04
摘要： This invention relates to compounds of the Formula (1) wherein G, A, Z, Q, X, Y, and R1 and R2 are defined as in the specification, pharmaceutical compositions containing them and their use in the treatment of central nervous system and other disorders.
摘要翻译：本发明涉及式（1）的化合物，其中G，A，Z，Q，X，Y和R 1和R 2如说明书中所定义，含有它们的药物组合物及其在治疗中枢神经系统中的用途其他疾病。

4. 发明申请

WO2003053533A2 DETECTION APPARATUS AND COMPONENT DETECTABLE BY THE DETECTION APPARATUS 审中-公开
标题翻译：检测装置和检测装置可检测的组件
公开(公告)号：WO2003053533A2
公开(公告)日：2003-07-03
申请号：PCT/GB2002/005591
申请日：2002-12-10
申请人： INNOVISION RESEARCH & TECHNOLOGY PLC , MAPLESTON, David, Bernard , WHITE, Andrew, David
发明人： MAPLESTON, David, Bernard , WHITE, Andrew, David
IPC分类号： A63H5/00
CPC分类号： G06K7/10128 , G01V3/081 , G06K7/0008 , G06K19/0723 , G07D7/04
摘要： A detection system has a detection apparatus and a detectable component detectable by the detection apparatus. The detectable component (3) has a magnetic element (4) movable relative to the detection apparatus and the detection apparatus includes: an oscillator (10) for providing an oscillating signal; a detection component (20) coupled to receive the oscillating signal, the detection component having an impedance that varies with magnetic field when the oscillating signal is supplied to the detection component; a sensor (21, 22', 23, 24, 25, 2'6, 27, 31) for sensing variation in the impedance of the detection component (20); and an output (34) for providing an output in accordance with variation of the impedance sensed by the sensor means and resulting from movement of the magnetic element (4) relative to the detection apparatus. The detection system may be or form part of a toy or game.
摘要翻译：检测系统具有可由检测装置检测的检测装置和可检测部件。可检测部件（3）具有相对于检测装置可移动的磁性元件（4），检测装置包括：振荡器（10），用于提供振荡信号; 耦合以接收所述振荡信号的检测部件（20），所述检测部件具有当所述振荡信号被提供给所述检测部件时随磁场而变化的阻抗; 用于检测所述检测部件（20）的阻抗的变化的传感器（21,22'，23,24,25,26,67,31）。以及输出（34），用于根据由传感器装置感测的阻抗的变化提供输出，并且由磁性元件（4）相对于检测装置的移动而产生。检测系统可以是或形成玩具或游戏的一部分。

5. 发明申请

WO2003053533A3 DETECTION APPARATUS AND COMPONENT DETECTABLE BY THE DETECTION APPARATUS 审中-公开
公开(公告)号：WO2003053533A3
公开(公告)日：2003-07-03
申请号：PCT/GB2002/005591
申请日：2002-12-10
申请人： INNOVISION RESEARCH & TECHNOLOGY PLC , MAPLESTON, David, Bernard , WHITE, Andrew, David
发明人： MAPLESTON, David, Bernard , WHITE, Andrew, David
IPC分类号： G01V3/08
摘要： A detection system has a detection apparatus and a detectable component detectable by the detection apparatus. The detectable component (3) has a magnetic element (4) movable relative to the detection apparatus and the detection apparatus includes: an oscillator (10) for providing an oscillating signal; a detection component (20) coupled to receive the oscillating signal, the detection component having an impedance that varies with magnetic field when the oscillating signal is supplied to the detection component; a sensor (21, 22', 23, 24, 25, 2'6, 27, 31) for sensing variation in the impedance of the detection component (20); and an output (34) for providing an output in accordance with variation of the impedance sensed by the sensor means and resulting from movement of the magnetic element (4) relative to the detection apparatus. The detection system may be or form part of a toy or game.

6. 发明申请

WO2003054825A3 DETECTABLE COMPONENTS AND DETECTION APPARATUS FOR DETECTING SUCH COMPONENTS 审中-公开
公开(公告)号：WO2003054825A3
公开(公告)日：2003-07-03
申请号：PCT/GB2002/005583
申请日：2002-12-10
申请人： INNOVISION RESEARCH & TECHNOLOGY PLC , BROOKS, Colin, Philip , MAPLESTON, David, Bernard , SYMONS, Peter, Robert , WHITE, Andrew, David
发明人： BROOKS, Colin, Philip , MAPLESTON, David, Bernard , SYMONS, Peter, Robert , WHITE, Andrew, David
IPC分类号： G01V15/00
摘要： A detectable component has a first inductive coupler (L;M) adapted to couple inductively to a second inductive coupler (L1) of a detection apparatus when the detectable component is in range of or coupled to the detection apparatus. The first inductive coupler has a resistive component (M) with a resistance that varies with magnetic field to cause modulation of a carrier signal supplied to the second inductive coupler of the detection apparatus, the detectable component having a characteristic signature that enables the detectable component to be distinguished by the detection apparatus from other such detectable components having different characteristic signatures.

7. 发明申请

WO2002050802A3 AN INFORMATION PROVIDING APPARATUS 审中-公开
公开(公告)号：WO2002050802A3
公开(公告)日：2002-06-27
申请号：PCT/GB2001/005680
申请日：2001-12-19
申请人： INNOVISION RESEARCH & TECHNOLOGY PLC , PITT-PLADDY, Glen , FEUCHTWANGER, David , WHITE, Andrew, David , HILLS, Andrew , UNDERWOOD, Richard
发明人： PITT-PLADDY, Glen , FEUCHTWANGER, David , WHITE, Andrew, David , HILLS, Andrew , UNDERWOOD, Richard
IPC分类号： G06K7/12
摘要： An information providing apparatus such as a question and answer game has: a substrate (3) carrying visually identifiable ink dots comprising first and second inks of the same colour with one of said first and second inks comprising an ink that emits radiation of a first wavelength in response to receipt of radiation of a second wavelength different from the first wavelength; a detector (4) for detecting radiation of the first wavelength and for providing a detection signal indicating whether or not radiation of the first wavelength has been detected; and user advising means (9) for advising a user when the detector is receiving radiation of the first wavelength.

8. 发明申请

WO2006090273A2 [1,8]NAPHTHYRIDIN-2-ONES AND RELATED COMPOUNDS WITH KETO OR HYDROXYL LINKERS FOR THE TREATMENT OF SCHIZOPHRENIA 审中-公开
标题翻译： [1,8]萘啶-2-酮及用酮基或羟基连接基治疗精神分裂症的相关化合物
公开(公告)号：WO2006090273A2
公开(公告)日：2006-08-31
申请号：PCT/IB2006/000477
申请日：2006-02-14
申请人： WARNER-LAMBERT COMPANY LLC , JOHNSON, Douglas, Scott , SINGER, Jamie, Marie , WHITE, Andrew, David
发明人： JOHNSON, Douglas, Scott , SINGER, Jamie, Marie , WHITE, Andrew, David
IPC分类号： C07D471/04 , A61K31/4375 , A61P25/18
CPC分类号： C07D471/04
摘要： Compounds of formula (I) are disclosed. A of formula 1 is -(CH 2 ) m CO- or -(CH 2 ) m COH-, wherein m is an integer from 2 to 5 and wherein one or two of the carbon atoms can be substituted as described in the specification. G, D, Z, Q, X, Y, R 1 , and R 4 through R 7 of formula 1 are defined in the specification. Also provided are descriptions of processes for preparing compounds of formula 1, intermediates used in making the same, and pharmaceutical compositions containing such compounds and their use in the treatment of central nervous system disorders and other disorders.
摘要翻译：公开了式（I）的化合物。式1中的A是 - （CH 2）m -CO-或 - （CH 2）m COH- ，其中m是2至5的整数，并且其中一个或两个碳原子可以如说明书中所述被取代。在说明书中定义了式1的G，D，Z，Q，X，Y，R 1，R 4和R 7至R 7 。还提供了制备式1化合物的方法的描述，用于制备它的中间体，以及含有这些化合物的药物组合物及其在治疗中枢神经系统疾病和其他疾病中的用途。

9. 发明申请

WO2003054825A2 DETECTABLE COMPONENTS AND DETECTION APPARATUS FOR DETECTING SUCH COMPONENTS 审中-公开
标题翻译：检测组件和用于检测这些组件的检测装置
公开(公告)号：WO2003054825A2
公开(公告)日：2003-07-03
申请号：PCT/GB2002/005583
申请日：2002-12-10
申请人： INNOVISION RESEARCH & TECHNOLOGY PLC , BROOKS, Colin, Philip , MAPLESTON, David, Bernard , SYMONS, Peter, Robert , WHITE, Andrew, David
发明人： BROOKS, Colin, Philip , MAPLESTON, David, Bernard , SYMONS, Peter, Robert , WHITE, Andrew, David
IPC分类号： G08C17/00
CPC分类号： G06K7/10128 , G01R33/02 , G01V3/081 , G01V15/00 , G06K7/0008 , G06K19/0723 , G07D7/04
摘要： A detectable component has a first inductive coupler (L;M) adapted to couple inductively to a second inductive coupler (L1) of a detection apparatus when the detectable component is in range of or coupled to the detection apparatus. The first inductive coupler has a resistive component (M) with a resistance that varies with magnetic field to cause modulation of a carrier signal supplied to the second inductive coupler of the detection apparatus, the detectable component having a characteristic signature that enables the detectable component to be distinguished by the detection apparatus from other such detectable components having different characteristic signatures.
摘要翻译：当可检测组件在检测装置的范围内或耦合到检测装置时，可检测组件具有适于将感应耦合到检测装置的第二电感耦合器（L1）的第一感应耦合器（L; M）。第一电感耦合器具有电阻分量（M），其电阻随磁场而变化，从而调制提供给检测装置的第二感应耦合器的载波信号，该可检测部件具有使得可检测部件能够通过检测装置与具有不同特性特征的其它这种可检测组件区分开来。

10. 发明申请

WO2002052419A3 DATA COMMUNICATION APPARATUS 审中-公开
公开(公告)号：WO2002052419A3
公开(公告)日：2002-07-04
申请号：PCT/GB2001/005690
申请日：2001-12-20
申请人： INNOVISION RESEARCH & TECHNOLOGY PLC , PITT-PLADDY, Glen , FEUCHTWANGER, David , WHITE, Andrew, David , HILLS, Andrew
发明人： PITT-PLADDY, Glen , FEUCHTWANGER, David , WHITE, Andrew, David , HILLS, Andrew
IPC分类号： G06K7/00
摘要： A base module (2) has a subsidiary unit receiving area (3b) having a first electrical coupler (LC1). A subsidiary unit (4) has a memory (231) and a second electrical coupler (LC2) arranged to couple to the first electrical coupler when the subsidiary unit is received on the subsidiary unit receiving area (3b). The base module (2) has a signal supplier (10, 21) for supplying a signal to the subsidiary unit (4) when the first and second electrical couplers (LC1 and LC2) are coupled and a data communicator (10, 22) for interrupting the signal in accordance with data to be communicated to the subsidiary unit to provide to the first coupler (LC1) an interrupted signal having interruptions dependent upon the data to be communicated. The data communicator is arranged to send the data as data bits each followed by a confirmation bit and the subsidiary unit has a data returner (33, M1) for modifying the received signal to return the received data as it is received so that each returned data bit is followed by the inverse of the corresponding confirmation bit.

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