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1. 发明申请

WO2005092840A1 FORMAMIDE DERIVATIVES USEFUL AS ADRENOCEPTOR 审中-公开
标题翻译：甲醛衍生物有用作ADRENOCEPTOR
公开(公告)号：WO2005092840A1
公开(公告)日：2005-10-06
申请号：PCT/IB2005/000619
申请日：2005-03-10
申请人： PFIZER LIMITED , PFIZER INC. , BROWN, Alan, Daniel , BUNNAGE, Mark, Edward , GLOSSOP, Paul, Alan , JAMES, Kim , LANE, Charlotte, Alice, Louise , LEWTHWAITE, Russell, Andrew , PRICE, David, Anthony
发明人： BROWN, Alan, Daniel , BUNNAGE, Mark, Edward , GLOSSOP, Paul, Alan , JAMES, Kim , LANE, Charlotte, Alice, Louise , LEWTHWAITE, Russell, Andrew , PRICE, David, Anthony
IPC分类号： C07C233/43
CPC分类号： C07C237/20 , C07C237/30 , C07C237/32 , C07C255/60 , C07C311/37 , C07C311/46 , C07C317/32 , C07C323/32 , C07C323/41 , C07C323/42 , C07C2601/14 , C07C2602/08 , C07C2603/74 , C07D209/48 , C07D211/32 , C07D213/38 , C07D213/40 , C07D217/06 , C07D217/16 , C07D221/22 , C07D221/24 , C07D295/192 , C07D335/02
摘要： The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
摘要翻译：本发明涉及式（1）化合物以及制备用于制备含这些衍生物的组合物和用途的中间体的方法。根据本发明的化合物可用于许多疾病，病症和病症，特别是炎症，过敏和呼吸道疾病，病症和病症。

2. 发明申请

WO2005092860A1 COMPOUNDS FOR THE TREATMENT OF DISEASES 审中-公开
标题翻译：治疗疾病的化合物
公开(公告)号：WO2005092860A1
公开(公告)日：2005-10-06
申请号：PCT/IB2005/000669
申请日：2005-03-11
申请人： PFIZER LIMITED , PFIZER INC , BROWN, Alan, Daniel , BUNNAGE, Mark, Edward , GLOSSOP, Paul, Alan , JAMES, Kim , LANE, Charlotte, Alice, Louise , LEWTHWAITE, Russell, Andrew , PRICE, David, Anthony
发明人： BROWN, Alan, Daniel , BUNNAGE, Mark, Edward , GLOSSOP, Paul, Alan , JAMES, Kim , LANE, Charlotte, Alice, Louise , LEWTHWAITE, Russell, Andrew , PRICE, David, Anthony
IPC分类号： C07D213/65
CPC分类号： C07D401/12 , C07D213/65
摘要： The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
摘要翻译：本发明涉及式（1）的化合物和用于制备用于制备含有这些衍生物的组合物和其用途的中间体的方法。根据本发明的化合物可用于许多疾病，病症和病症，特别是炎性，变应性和呼吸系统疾病，病症和病症。

3. 发明申请

WO2005092887A1 COMPOUNDS FOR THE TREATMENT OF DISEASES 审中-公开
标题翻译：化合物治疗疾病
公开(公告)号：WO2005092887A1
公开(公告)日：2005-10-06
申请号：PCT/IB2005/000699
申请日：2005-03-10
申请人： PFIZER LIMITED , PFIZER INC. , BROWN, Alan, Daniel , BUNNAGE, Mark, Edward , GLOSSOP, Paul, Alan , JAMES, Kim , LANE, Charlotte, Alice, Louise , LEWTHWAITE, Russell, Andrew , PRICE, David, Anthony
发明人： BROWN, Alan, Daniel , BUNNAGE, Mark, Edward , GLOSSOP, Paul, Alan , JAMES, Kim , LANE, Charlotte, Alice, Louise , LEWTHWAITE, Russell, Andrew , PRICE, David, Anthony
IPC分类号： C07D413/04
CPC分类号： C07C311/46 , C07C237/20 , C07C237/30 , C07C237/32 , C07C323/41 , C07C2601/14 , C07C2601/18 , C07C2602/08 , C07C2603/74 , C07D211/58 , C07D213/40 , C07D217/06 , C07D231/40 , C07D413/04
摘要： The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
摘要翻译：本发明涉及式（1）化合物以及制备用于制备含这些衍生物的组合物和用途的中间体的方法。根据本发明的化合物可用于许多疾病，病症和病症，特别是炎症，过敏和呼吸道疾病，病症和病症。

4. 发明申请

WO2005092841A1 COMPOUNDS HAVING BETA-AGONIST ACTIVITY 审中-公开
标题翻译：具有BETA激动剂活性的化合物
公开(公告)号：WO2005092841A1
公开(公告)日：2005-10-06
申请号：PCT/IB2005/000637
申请日：2005-03-10
申请人： PFIZER LIMITED , PFIZER INC. , BROWN, Alan, Daniel , BUNNAGE, Mark, Edward , BUTCHER, Kenneth, John , GLOSSOP, Paul, Alan , JAMES, Kim , LANE, Charlotte, Alice, Louise , LEWTHWAITE, Russell, Andrew , PRICE, David, Anthony
发明人： BROWN, Alan, Daniel , BUNNAGE, Mark, Edward , BUTCHER, Kenneth, John , GLOSSOP, Paul, Alan , JAMES, Kim , LANE, Charlotte, Alice, Louise , LEWTHWAITE, Russell, Andrew , PRICE, David, Anthony
IPC分类号： C07C237/20
CPC分类号： C07C237/30 , C07C237/20 , C07C275/40 , C07D211/22 , C07D211/52 , C07D213/40 , C07D213/74 , C07D213/75 , C07D217/06 , C07D233/56
摘要： The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
摘要翻译：本发明涉及式（1）化合物以及制备用于制备含这些衍生物的组合物和用途的中间体的方法。根据本发明的化合物可用于许多疾病，病症和病症，特别是炎症，过敏和呼吸道疾病，病症和病症。

5. 发明申请

WO2005090287A2 COMPOUNDS USEFUL FOR THE TREATMENT OF DISEASES 审中-公开
标题翻译：可用于治疗疾病的化合物
公开(公告)号：WO2005090287A2
公开(公告)日：2005-09-29
申请号：PCT/IB2005/000640
申请日：2005-03-10
申请人： PFIZER LIMITED , PFIZER INC. , BROWN, Alan, Daniel , BUNNAGE, Mark, Edward , GLOSSOP, Paul, Alan , JAMES, Kim , LANE, charlotte, Alice, Louise , LEWTHWAITE, Russell, Andrew , LUNN, Graham , PRICE, David, Anthony
发明人： BROWN, Alan, Daniel , BUNNAGE, Mark, Edward , GLOSSOP, Paul, Alan , JAMES, Kim , LANE, charlotte, Alice, Louise , LEWTHWAITE, Russell, Andrew , LUNN, Graham , PRICE, David, Anthony
IPC分类号： C07C237/00
CPC分类号： C07D217/06
摘要： The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
摘要翻译：本发明涉及式（1）的化合物以及制备用于制备含这些衍生物的组合物和用途的中间体的方法。根据本发明的化合物可用于许多疾病，病症和病症，特别是炎性，过敏和呼吸道疾病，病症和病症。

6. 发明申请

WO2005080313A3 SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES 审中-公开
公开(公告)号：WO2005080313A3
公开(公告)日：2005-09-01
申请号：PCT/IB2005/000086
申请日：2005-01-12
申请人： PFIZER LIMITED , PFIZER INC. , BROWN, Alan, Daniel , BUNNAGE, Mark, Edward , GLOSSOP, Paul, Alan , JAMES, Kim , LANE, Charlotte, Alice, Louise , LEWTHWAITE, Russell, Andrew , MOSES, Ian, Brian , PRICE, David, Anthony , THOMSON, Nicholas, Murray
发明人： BROWN, Alan, Daniel , BUNNAGE, Mark, Edward , GLOSSOP, Paul, Alan , JAMES, Kim , LANE, Charlotte, Alice, Louise , LEWTHWAITE, Russell, Andrew , MOSES, Ian, Brian , PRICE, David, Anthony , THOMSON, Nicholas, Murray
IPC分类号： C07C311/08
摘要： The invention relates to compounds of formula (1) and to processes for the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.

7. 发明申请

WO2006051373A1 COMPOUNDS FOR THE TREATMENT OF DISEASES 审中-公开
标题翻译：化合物治疗疾病
公开(公告)号：WO2006051373A1
公开(公告)日：2006-05-18
申请号：PCT/IB2005/003284
申请日：2005-10-31
申请人： PFIZER LIMITED , PFIZER INC. , GLOSSOP, Paul, Alan , LANE, Charlotte, Alice, Louise , LUNN, Graham , PRICE, David, Anthony
发明人： GLOSSOP, Paul, Alan , LANE, Charlotte, Alice, Louise , LUNN, Graham , PRICE, David, Anthony
IPC分类号： C07C233/05 , C07C233/10 , C07C233/43 , C07C311/16 , A61K31/16 , A61K31/18 , A61K31/165 , A61K31/166
CPC分类号： C07C215/60 , C07C233/40 , C07C311/08 , C07C311/18 , C07D213/73
摘要： The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
摘要翻译：本发明涉及式（1）化合物以及制备用于制备含这些衍生物的组合物和用途的中间体的方法。根据本发明的化合物可用于许多疾病，病症和病症，特别是炎症，过敏和呼吸道疾病，病症和病症。

8. 发明申请

WO2006056848A1 OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES 审中-公开
标题翻译： OCTAHYDROPRROLO [3,4-C]吡咯烷酮衍生物
公开(公告)号：WO2006056848A1
公开(公告)日：2006-06-01
申请号：PCT/IB2005/003478
申请日：2005-11-10
申请人： PFIZER LIMITED , PFIZER INC. , LANE, Charlotte, Alice, Louise , PRICE, David, Anthony
发明人： LANE, Charlotte, Alice, Louise , PRICE, David, Anthony
IPC分类号： C07D487/04 , A61K31/407 , A61K31/4184 , A61P11/06 , A61P37/08
CPC分类号： C07D487/04
摘要： The present invention relates to octahydropyrrolo[3,4-c]pyrrole derivatives of formula (I): and to processes for the preparation thereof, compositions containing the same and the uses thereof.
摘要翻译：本发明涉及式（I）的八氢吡咯并[3,4-c]吡咯衍生物及其制备方法，其含有该组合物的组合物及其用途。

9. 发明申请

WO2004029051A1 PYRAZOLE AMIDES FOR TREATING HIV INFECTIONS 审中-公开
标题翻译：用于治疗艾滋病毒感染的吡唑类药物
公开(公告)号：WO2004029051A1
公开(公告)日：2004-04-08
申请号：PCT/IB2003/004071
申请日：2003-09-15
申请人： PFIZER LIMITED , PFIZER INC. , JONES, Lyn, Howard , MOWBRAY, Charles, Eric , PRICE, David, Anthony , SELBY, Matthew, Duncan , STUPPLE, Paul, Anthony
发明人： JONES, Lyn, Howard , MOWBRAY, Charles, Eric , PRICE, David, Anthony , SELBY, Matthew, Duncan , STUPPLE, Paul, Anthony
IPC分类号： C07D471/04
CPC分类号： C07D417/04 , C07D401/06 , C07D403/06 , C07D471/04 , C07D487/04
摘要： This invention relates to pyrazole derivatives of formula (I) or pharmaceutically acceptable salts, solvates or derivative thereof, wherein R' to R4, n W, X and Y are defined in the description, and to processes for the preparation thereof, intermediates used in their preparation of, compositions containing them and the uses of such derivatives. The compounds of the present invention bind to the enzyme reverse transcriptase and are modulators, especially inhibitors thereof. As such the compounds of the present invention are useful ín the treatment of a variety of disorders including those in which the inhibition of reverse transcriptase is implicated. Disorders of interest include those caused by Human Immunodificiency Virus (HIV) and genetically related retroviruses, such as Acquired Immune Deficiency Syndrome (AIDS).
摘要翻译：本发明涉及式（I）的吡唑衍生物或其药学上可接受的盐，溶剂化物或衍生物，其中R'至R 4，n W，X和Y在说明书中定义，及其制备方法，它们的制备，含有它们的组合物和这些衍生物的用途。本发明的化合物与酶逆转录酶结合，是调节剂，特别是其抑制剂。因此，本发明的化合物可用于治疗各种病症，包括其中涉及逆转录酶的抑制的病症。感兴趣的疾病包括由人免疫缺陷病毒（HIV）引起的遗传相关逆转录病毒，如获得性免疫缺陷综合征（AIDS）。

10. 发明申请

WO2004031178A1 PYRAZOLE DERIVATIVES 审中-公开
标题翻译：吡唑衍生物
公开(公告)号：WO2004031178A1
公开(公告)日：2004-04-15
申请号：PCT/IB2003/004205
申请日：2003-09-24
申请人： PFIZER LIMITED , PFIZER INC. , PRICE, David, Anthony , SELBY, Matthew, Duncan , STUPPLE, Paul, Anthony
发明人： PRICE, David, Anthony , SELBY, Matthew, Duncan , STUPPLE, Paul, Anthony
IPC分类号： C07D403/06
CPC分类号： C07D471/04 , C07D403/06
摘要： This invention relates to pyrazole derivatives of formula (I) or pharmaceutically acceptable salts, solvates or derivative thereof, wherein R 1 to R 4 , n W, X and Y are defined in the description, and to processes for the preparation thereof, intermediates used in their preparation of, compositions containing them and the uses of such derivatives. The compounds of the present invention bind to the enzyme reverse transcriptase and are modulators, especially inhibitors thereof. As such the compounds of the present invention are useful in the treatment of a variety of disorders including those in which the inhibition of reverse transcriptase is implicated. Disorders of interest include those caused by Human Immunodificiency Virus (HIV) and genetically related retroviruses, such as Acquired Immune Deficiency Syndrome (AIDS).
摘要翻译：本发明涉及式（I）的吡唑衍生物或其药学上可接受的盐，溶剂化物或衍生物，其中R 1至R 4，n W，X和Y在说明书中定义，以及制备方法其制备中使用的含有它们的组合物和这些衍生物的用途。本发明的化合物与酶逆转录酶结合，是调节剂，特别是其抑制剂。因此，本发明的化合物可用于治疗各种病症，包括其中涉及逆转录酶的抑制的病症。感兴趣的疾病包括由人免疫缺陷病毒（HIV）引起的遗传相关逆转录病毒，如获得性免疫缺陷综合征（AIDS）。

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