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1. 发明申请

WO2007127894A3 PHOTODISINFECTION DELIVERY DEVICES & METHODS 审中-公开
公开(公告)号：WO2007127894A3
公开(公告)日：2007-11-08
申请号：PCT/US2007/067583
申请日：2007-04-27
申请人： ONDINE INTERNATIONAL LTD. , ROSE, Andreas , LOEBEL, Nicolas, G. , HERR, Guenter , JOHNSTON, Kyle , STREET, Cale , ANDERSON, Roger
发明人： ROSE, Andreas , LOEBEL, Nicolas, G. , HERR, Guenter , JOHNSTON, Kyle , STREET, Cale , ANDERSON, Roger
IPC分类号： A61N5/06
摘要： The present invention presents devices, kits, systems and methods that can be used to deliver and activate a photosensitizing composition in a cavity. For example, a device (100) of the present invention includes a member (10) having a base portion (11), an insert portion (13) adapted for insertion into the cavity, and a pocket (12) adapted for communication with a waveguide (14) which is connected to a light source (20) for delivering light to the device (100), wherein the pocket (12) includes a light dispersing section (18) that is adapted for light communication with distal end (16) of the waveguide (14) and desired illumination pattern for photodisinfection of the cavity is provided by at least one of the elements selected from the group consisting of: surface finish of the light dispersing section (18), geometry of the light dispersing section (18), surface finish of the member (10), geometry of the member (10), and a combination thereof. The present invention can be used for humans, other animals, and inanimate objects.

2. 发明申请

WO2007005313A1 A HAND PIECE FOR THE DELIEVERY OF LIGHT AND SYSTEM EMPLOYING THE HAND PIECE 审中-公开
标题翻译：用于轻装饰的手段和使用手表的系统
公开(公告)号：WO2007005313A1
公开(公告)日：2007-01-11
申请号：PCT/US2006/024272
申请日：2006-06-22
申请人： ONDINE INTERNATIONAL LTD. , ROSE, Andreas , HERR, Guenter , LOEBEL, Nicolas, G.
发明人： ROSE, Andreas , HERR, Guenter , LOEBEL, Nicolas, G.
IPC分类号： A61C1/08 , A61C19/00 , A61B19/00 , G02B6/38 , A61B1/07
CPC分类号： A61N5/0603 , A61B5/0088 , A61B18/22 , A61B2090/0813 , A61B2090/306 , A61C1/088 , A61C19/004 , A61F9/008 , A61F9/00802 , A61N5/0601 , A61N5/062 , A61N2005/0606 , A61N2005/0644 , G02B6/381
摘要： The invention described here is an improved hand piece (12) for the delivery of light and a system (10) employing the hand piece (12). The hand piece (12) typically includes a body (22) and an optical element (24) such as an optical fiber coextensive with the body (22). The system (10) can include a remote light source (40) and an optical element (42) (e.g., a source optical fiber) for providing light to the hand piece (12).
摘要翻译：这里描述的本发明是用于传送光的改进的手持件（12）和采用手持件（12）的系统（10）。手持件（12）通常包括主体（22）和诸如与主体（22）共同延伸的光纤的光学元件（24）。系统（10）可以包括用于向手持件（12）提供光的远程光源（40）和光学元件（42）（例如，源光纤）。

3. 发明申请

WO2007050432A1 OPTICAL ALIGMENT SYSTEM AND METHOD 审中-公开
标题翻译：光学颜料系统和方法
公开(公告)号：WO2007050432A1
公开(公告)日：2007-05-03
申请号：PCT/US2006/040936
申请日：2006-10-17
申请人： ONDINE INTERNATIONAL LTD. , ROSE, Andreas , HERR, Guenter , JOHNSTON, Kyle
发明人： ROSE, Andreas , HERR, Guenter , JOHNSTON, Kyle
IPC分类号： G02B6/42 , G02B6/32
CPC分类号： G02B6/4292 , G02B6/4204 , G02B6/4234 , G02B6/4236
摘要： The present invention provides an alignment system (100) comprising a base (10) having a feature (12) that accepts a first optical element (14), a first eccentric element (18) having a through hole (20) that accepts an eccentric assembly (22) comprising a second eccentric element (26) having a feature (28) that accepts a second optical element (30) and is attached to the second optical element (30) via second attachment means (32), wherein the first eccentric element (18) is engaged with the base (10) via first attachment means (24) and axial alignment between optical axis of the first optical element (14) and optical axis of the second optical element (30) is achieved by rotationally adjusting at least one of the eccentric elements (18, 26) relative to the base (10). The present invention also provides methods to make and use this alignment system (100).
摘要翻译：本发明提供了一种对准系统（100），其包括具有接收第一光学元件（14）的特征（12）的基座（10），具有通孔的第一偏心元件（20），所述偏心组件（22）包括第二偏心元件（26），所述第二偏心元件具有容纳第二光学元件（30）并且经由第二附接装置（32），其中第一偏心元件（18）经由第一附接装置（24）与基座（10）接合，并且第一光学元件（14）的光轴与第二光学元件（14）的光轴之间的轴向对准 30）通过相对于所述基座（10）旋转调节所述偏心元件（18,26）中的至少一个来实现。本发明还提供制造和使用该对准系统（100）的方法。

4. 发明申请

WO2006115761A1 OPTICAL PROBE FOR DELIVERY OF LIGHT 审中-公开
标题翻译：用于光输送的光学探头
公开(公告)号：WO2006115761A1
公开(公告)日：2006-11-02
申请号：PCT/US2006/013380
申请日：2006-04-11
申请人： ONDINE INTERNATIONAL LTD. , ROSE, Andreas , HERR, Guenter , RIDGE, Joe , JOHNSTON, Kyle
发明人： ROSE, Andreas , HERR, Guenter , RIDGE, Joe , JOHNSTON, Kyle
IPC分类号： A61B18/22 , A61N5/06
CPC分类号： A61N5/0603 , A61B18/22 , A61B2018/2238 , A61B2018/2261 , A61N5/0601 , A61N5/062 , A61N2005/0606 , A61N2005/0644
摘要： The present invention discloses an optical probe (10) employed for the delivery of light. More particularly, the present invention relates to an optical probe (10) that include a hand piece (12) a probe tip (14) or combination thereof and its uses for delivery of light to surfaces of tissue and other portions of the human body or other organisms.
摘要翻译：本发明公开了一种用于发光的光探针（10）。更具体地说，本发明涉及一种光学探针（10），其包括手部件（12），探针尖端（14）或其组合，以及用于将光递送到组织和人体的其他部分的表面或其他生物。

5. 发明申请

WO2008048832A3 PHOTODYNAMIC THERAPY DEVICE 审中-公开
公开(公告)号：WO2008048832A3
公开(公告)日：2008-04-24
申请号：PCT/US2007/080916
申请日：2007-10-10
申请人： ONDINE INTERNATIONAL LTD. , ROSE, Andreas , HERR, Guenter , JOHNSTON, Kyle
发明人： ROSE, Andreas , HERR, Guenter , JOHNSTON, Kyle
IPC分类号： A61N5/06 , A61C17/20
摘要： The invention described herein is an apparatus for performing photodynamic therapy comprising: a waveguide, a light source in communication with one end of the waveguide, a photodynamic tip Sn communication with another end of the waveguide wherein the photodynamic tip is designed to be securely but removably attached to a scaling tip of a sealer and the apparatus delivers light in a desired illumination pattern and in at least one predetermined wavelength to activate a photosensitizing composition for the killing of microbes. The invention also includes a method for using the apparatus in conjunction with a sealer to perform sonophotodynamic therapy and a method for making the apparatus.

6. 发明申请

WO2008133707A1 WAVEGUIDE CONNECTION DEVICE 审中-公开
标题翻译：波形连接装置
公开(公告)号：WO2008133707A1
公开(公告)日：2008-11-06
申请号：PCT/US2007/082217
申请日：2007-10-23
申请人： ONDINE INTERNATIONAL LTD. , ROSE, Andreas , JOHNSTON, Kyle , GUENTER, Herr
发明人： ROSE, Andreas , JOHNSTON, Kyle , GUENTER, Herr
IPC分类号： G02B6/38 , A61N5/067 , A61B18/24
CPC分类号： A61N5/0624 , A61N5/0601 , A61N5/062 , G02B6/3806 , G02B6/3809 , G02B6/3825 , G02B6/3855 , G02B6/3858
摘要： A connector (10) for interconnecting a waveguide (22) with a light component (18) (e.g., another waveguide) for allowing light communication therebetween. The end of the waveguide (22) is clamped between two surfaces (68,70) of the connector by means of a clamping member (60). One such surface can be a surface (68) of said clamping member. The axis (66) of the clamping member can extend laterally with respect to the connector axis (26). The clamping member can have a progessively increasing cross-sectional area. Assemblies for connecting a waveguide can be formed with the connector. In one embodiment, the connector is employed for connecting to a waveguide useful in performing medical applications such as provision of photodynamic therapy.
摘要翻译：用于将波导（22）与光分量（18）（例如，另一波导）互连的连接器（10），用于允许其间的光连通。通过夹紧构件（60）将波导（22）的端部夹持在连接器的两个表面（68,70）之间。一个这样的表面可以是所述夹紧构件的表面（68）。夹紧构件的轴线（66）可相对于连接器轴线（26）横向延伸。夹紧构件可以具有逐渐增加的横截面积。可以用连接器形成用于连接波导的组件。在一个实施例中，连接器用于连接到用于执行诸如提供光动力疗法的医学应用的波导管。

7. 发明申请

WO2006022970A1 SONOPHOTODYNAMIC THERAPY FOR DENTAL APPLICATIONS 审中-公开
标题翻译：用于牙科应用的SONOPHOTODYNAMIC治疗
公开(公告)号：WO2006022970A1
公开(公告)日：2006-03-02
申请号：PCT/US2005/019707
申请日：2005-06-03
申请人： ONDINE INTERNATIONAL LTD. , LOEBEL, Nicolas , MARTIN, Roy, Wallace , ROSE, Andreas
发明人： LOEBEL, Nicolas , MARTIN, Roy, Wallace , ROSE, Andreas
IPC分类号： A61N5/06
CPC分类号： A61N5/062 , A61C1/088 , A61C17/02 , A61C17/20 , A61N5/0601 , A61N2005/0606
摘要： The present invention includes methods for killing microbes in an oral cavity or wound comprising: applying a photosensitizing composition to a locus or a wound (102); applying a fluid and sonic energy to the locus or wound (104); and irradiating the locus or wound with a light source at a wavelength absorbed by the photosensitizing composition so as to destroy microbes at the locus or wound (106). The present invention also include methods for killing microbes in an oral cavity or wound comprising: applying a photosensitizing composition to a locus or a wound (202); and applying sufficient sonic energy to the locus or wound in order to provide acoustic cavitation so as to destroy microbes at the locus or wound (204). The present invention further provides an apparatus for providing sonophotodynamic therapy includes one or more members (12) in communication with one or more of the following: a sonic energy source (20); a therapeutic fluid source (26) and a light source (22).
摘要翻译：本发明包括杀死口腔或伤口中的微生物的方法，包括：将光敏组合物施用于场所或伤口（102）; 向所述场所或伤口施加流体和声波能量（104）; 用光敏组合物吸收的波长的光源照射所述轨迹或者伤口，以破坏所述场所或伤口处的微生物（106）。本发明还包括在口腔或伤口中杀死微生物的方法，包括：将光敏组合物施用于场所或伤口（202）; 并向轨迹或伤口施加足够的声能，以提供声空化，从而破坏位点或伤口处的微生物（204）。本发明还提供一种用于提供超声波动力疗法的装置，包括与以下一种或多种相通的一个或多个构件（12）：声能量源（20）; 治疗流体源（26）和光源（22）。

8. 发明申请

WO2006004644A1 OPTICAL SCANNER 审中-公开
标题翻译：光学扫描仪
公开(公告)号：WO2006004644A1
公开(公告)日：2006-01-12
申请号：PCT/US2005/022694
申请日：2005-06-28
申请人： LOEBEL, Nicolas , ROSE, Andreas , GITLIN, Mark , MELVILLE, David
发明人： LOEBEL, Nicolas , ROSE, Andreas , GITLIN, Mark , MELVILLE, David
IPC分类号： G02B7/182 , G02B26/10
CPC分类号： G02B26/105 , G02B7/1821 , G02B26/10 , H02K33/12 , H02K33/16
摘要： An optical scanner 100 comprising stators 38, 40 spaced apart from each other but ferromagnetically coupled together; a magnet 9 positioned relative to the stators 38, 40 such that axis of symmetry of a magnetic field created by the magnet 9 is substantially equidistant from and passes in between the stators 38, 40; and a flexure element 11 positioned relative to the stators 38, 40 and the magnet 9 such that its center point substantially intersects axis of symmetry of the magnet's 9 magnetic field, wherein the flexure element 11 is not in physical contact with either the stators 38, 40 or the magnet 9. A method for oscillating an optical scanner's flexure element comprising using a magnet 9 disposed between two stators 38, 40 and beneath the flexure element 11 to create two magnetic circuits 30, 31 that are generally symmetric and coplanar with one another, wherein a portion of the circuits share a common magnetic path through the magnet 9 and remaining, non-common paths of the circuits 30, 31 through the stators 38, 40 are counter-directional relative to each other; applying electromagnetic flux to such circuits 30, 31 via stator electrical coils 5, 6 enhancing flux through one circuit 30 or 31 while impeding flux through the other circuit 30 or 31 and keeping the stator-induced flux vector through the magnet 9 unchanged; and reversing polarity of the stator-induced electromagnetic flux at a regular frequency in order to oscillate the flexure element 11.
摘要翻译：光学扫描器100包括彼此间隔开但铁磁耦合在一起的定子38,40; 相对于定子38,44定位的磁体9，使得由磁体9产生的磁场的对称轴线基本上与定子38,40之间等距并且通过定子38,40; 以及相对于定子38,40和磁体9定位的挠曲元件11，使得其中心点基本上与磁体9的磁场的对称轴线相交，其中，挠曲元件11不与定子38,34,40和 40或磁体9.一种用于振荡光学扫描仪的挠曲元件的方法，包括使用设置在两个定子38,40之间的磁体9并且在挠曲元件11下方形成两个彼此大致对称和共面的磁路30,31 其中一部分电路共享通过磁体9的公共磁路，并且电路30,31的剩余的非公共路径通过定子38,40相对于彼此是相反方向的; 通过定子电线圈5,6向这种电路30,31施加电磁通量，增强通过一个电路30或31的磁通，同时阻碍通过另一个电路30或31的磁通，并且使定子感应的磁通矢量保持不变; 并以正常频率反转定子感应电磁通量的极性，以便使挠曲元件11振荡。

9. 发明申请

WO2012136287A1 ANFAHRHILFE FÜR EIN FAHRZEUG 审中-公开
标题翻译：牵引用于车辆
公开(公告)号：WO2012136287A1
公开(公告)日：2012-10-11
申请号：PCT/EP2012/000178
申请日：2012-01-17
申请人： KIPPE, Michael , ROSE, Andreas , BISCHOPINK, Christian , LOHMEIER, Frank
发明人： KIPPE, Michael , ROSE, Andreas , BISCHOPINK, Christian , LOHMEIER, Frank
IPC分类号： B60C27/22 , B60C11/16
CPC分类号： B60C27/22 , B60C11/1612
摘要： Die Erfindung betrifft einen luftbefüIIbaren Hilfsreifen (1) mit wenigstens einer Lauffläche (2), wobei auf der Lauffläche (2) reibungserhöhende Elemente (3) angeordnet sind. Der Hilfsreifen (1) ist zusätzlich zu einem Fahrzeugreifen (4) in dessen Bereich am Fahrzeug angeordnet. Der Hilfsreifen (1) kann in einer in die Lauffläche des Fahrzeugreifens (4) eingebrachten Nut (6) angeordnet sein, wobei die Nut (6) in Abrollrichtung des Fahrzeugreifens (4) verläuft, und wobei der Hilfsreifen (1) als elastischer Schlauchreifen ausgeführt ist. Gemäß der Erfindung kann der Hilfsreifen (1) auch ein separater Reifen auf einer eigenen Felge (7) sein, wobei der Hilfsreifen (1) parallel zu dem Fahrzeugreifen (4) am Fahrzeug angeordnet ist.
摘要翻译：本发明涉及一种辅助luftbefüIIbaren轮胎（1）与（2）中，运行表面（2）上的摩擦元件（3）被布置成至少一个运行表面。辅助轮胎（1）除了车辆轮胎（4）布置在所述车辆的区域中。辅助轮胎（1）可以设置引入到在所述车辆轮胎（4）中，槽的外胎面（6），所述槽（6）在车辆轮胎的滚动（4）延伸，并且其中，所述辅助轮胎（1）的作为弹性管状执行是。根据本发明的辅助轮胎（1）也可以是在其自己的轮辋上的轮胎分开（7），所述辅助轮胎（1）并行（4）车辆的轮胎被布置在车辆上。

10. 发明申请

WO2009102756A1 LIGHT DELIVERY DEVICE THAT PROVIDES A RADIAL LIGHT OUTPUT PATTERN 审中-公开
标题翻译：提供径向光输出图案的光输送装置
公开(公告)号：WO2009102756A1
公开(公告)日：2009-08-20
申请号：PCT/US2009/033744
申请日：2009-02-11
申请人： ROSE, Andreas , BISSIG, Alois , ZURFLUH, Erich
发明人： ROSE, Andreas , BISSIG, Alois , ZURFLUH, Erich
IPC分类号： A61N5/06
CPC分类号： A61N5/0603 , A61B2018/2261 , A61N5/0601 , A61N5/062 , A61N5/0624 , A61N2005/0644
摘要： A light delivery device (100) comprising an optical fiber (10) having a non- feature portion (16) and a feature portion (18) having features (20) that force light to couple out radially from the feature portion (18) and provide a desired radial light output pattern. A method of photodisinfection of a cavity comprising of providing this device (100), apply a photosensitizing composition (48) to treatment site within the cavity, and inserting at least a portion of the device (100) into the cavity; and applying light delivered by the device (100) from a light source to the treatment site within the cavity at a wavelength absorbed by the photosensitizing composition so as to inhibit or eliminate microbes located at the treatment site. The present invention also includes a method of making the device and a treatment kit containing the device (100) and a container (50) containing a photosensitizing composition (48).
摘要翻译：一种光输送装置（100），包括具有非特征部分（16）的光纤（10）和具有强制光从特征部分（18）径向耦合的特征（20）的特征部分（18）和提供期望的径向光输出图案。一种对空腔进行光学感应的方法，包括提供该装置（100），将光敏组合物（48）施加到空腔内的处理部位，并将装置（100）的至少一部分插入空腔中; 以及将来自光源的装置（100）传送的光以光敏组合物吸收的波长施加到空腔内的处理部位，以抑制或消除位于处理部位的微生物。本发明还包括制造该装置和包含装置（100）和包含光敏组合物（48）的容器（50）的处理套件的方法。

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