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1. 发明申请

WO2009117112A2 POWDER DISPERSION APPARATUS, METHOD OF MAKING AND USING THE APPARATUS, COMPONENTS THAT CAN BE USED ON THE APPARATUS AND OTHER DEVICES, AND VARIOUS ACTIVE AGENTS 审中-公开
标题翻译：粉末分散装置，制造和使用装置的方法，可用于装置和其他装置的组件以及各种活性剂
公开(公告)号：WO2009117112A2
公开(公告)日：2009-09-24
申请号：PCT/US2009/001716
申请日：2009-03-18
申请人： NOVARTIS AG , GLUSKER, Mark , ALSTON, William, W. , AXFORD, George, S. , PALMER-FELGATE, John , WILKINS, Jonathan , FOSS, Willard, R. , RAO, Nagaraja , POSTICH, Mark , PAKALA, Neeraj R. , MALTZ, David S. , WEERS, Jeffry G. , COHEN, Gal , UNG, Keith Try
发明人： GLUSKER, Mark , ALSTON, William, W. , AXFORD, George, S. , PALMER-FELGATE, John , WILKINS, Jonathan , FOSS, Willard, R. , RAO, Nagaraja , POSTICH, Mark , PAKALA, Neeraj R. , MALTZ, David S. , WEERS, Jeffry G. , COHEN, Gal , UNG, Keith Try
IPC分类号： A61M15/00
CPC分类号： A61M15/0028 , A61M11/001 , A61M15/0005 , A61M15/0016 , A61M15/0035 , A61M15/0038 , A61M15/0041 , A61M2202/064
摘要： Methods and apparatuses for the pulmonary delivery of a composition, such as methods and apparatuses for dispersing dry powder medicaments for inhalation by a patient. Elements or aspects of the apparatuses, including receptacle puncturing mechanisms, deoccluding devices, receptacle impacting devices, and receptacle lock devices or systems.
摘要翻译：用于肺部输送组合物的方法和装置，例如用于分散用于吸入患者的干粉药物的方法和装置。装置的元件或方面，包括插座穿孔机构，去电装置，插座冲击装置以及插座锁定装置或系统。

2. 发明申请

WO2008051621A2 POWDER DISPERSION APPARATUS, METHOD OF MAKING AND USING THE APPARATUS, AND COMPONENTS THAT CAN BE USED ON THE APPARATUS AND OTHER DEVICES 审中-公开
标题翻译：粉末扩散装置，制造和使用该装置的方法以及可用于该装置和其他装置的部件
公开(公告)号：WO2008051621A2
公开(公告)日：2008-05-02
申请号：PCT/US2007/022830
申请日：2007-10-25
申请人： NEKTAR THERAPEUTICS , GLUSKER, Mark , ALSTON, William, W. , AXFORD, George, S. , PALMER-FELGATE, John , WILKINS, Jonathan , FOSS, Willard, R. , RAO, Nagaraja , POSTICH, Mark , PAKALA, Neeraf, R. , MALTZ, David, S. , UNG, Keith
发明人： GLUSKER, Mark , ALSTON, William, W. , AXFORD, George, S. , PALMER-FELGATE, John , WILKINS, Jonathan , FOSS, Willard, R. , RAO, Nagaraja , POSTICH, Mark , PAKALA, Neeraf, R. , MALTZ, David, S. , UNG, Keith
IPC分类号： A61M15/00
CPC分类号： A61M15/0028 , A61M11/001 , A61M15/0005 , A61M15/0016 , A61M15/0036 , A61M15/0041 , A61M15/0048 , A61M15/0051 , A61M15/0081 , A61M15/0093 , A61M15/0096 , A61M2016/0015 , A61M2202/064 , A61M2205/43 , A61M2205/581 , A61M2205/582
摘要： Methods and apparatuses for the pulmonary delivery of a composition, such as methods and apparatuses for dispersing dry powder medicaments for inhalation by a patient. Elements or aspects of the apparatuses, including receptacle puncturing mechanisms, deoccluding devices, receptacle impacting devices, and receptacle lock devices or systems.
摘要翻译：用于肺部递送组合物的方法和设备，例如用于分散干粉药物以供患者吸入的方法和设备。装置的元件或方面，包括插座穿刺机构，去阻挡装置，插座撞击装置和插座锁装置或系统。

3. 发明申请

WO2007030162A2 VALVES, DEVICES, AND METHODS FOR ENDOBRONCHIAL THERAPY 审中-公开
标题翻译：阀门，装置和方法用于内部治疗
公开(公告)号：WO2007030162A2
公开(公告)日：2007-03-15
申请号：PCT/US2006/019446
申请日：2006-05-18
申请人： NEKTAR THERAPEUTICS , CECKA, Walter , ALSTON, William, W. , SMITH, Adrian, E. , HALL, Gregory, W. , FISHER, Winfield , COHEN, Gal
发明人： CECKA, Walter , ALSTON, William, W. , SMITH, Adrian, E. , HALL, Gregory, W. , FISHER, Winfield , COHEN, Gal
IPC分类号： A61M16/20 , F16K15/14
CPC分类号： A61M16/208 , A61M11/00 , A61M15/00 , A61M15/0015 , A61M15/0018 , A61M15/025 , A61M16/0833 , A61M16/0841 , A61M16/1045 , F16K1/18 , F16K15/14 , F16K15/148 , Y10T137/7891
摘要： Various valves, adapters, ventilator circuits, and methods are disclosed. In one or more embodiments, a valve includes a support that includes a plurality of apertures. The support includes a center and an outer edge. The plurality of flaps includes a flap for each aperture. Each flap has an end connected proximal to the center of the support. Each flap is capable of moving between a closed position and an opened position.
摘要翻译：公开了各种阀，适配器，呼吸机回路和方法。在一个或多个实施例中，阀包括包括多个孔的支撑件。支撑件包括中心和外缘。多个翼片包括用于每个孔的翼片。每个翼片具有靠近支撑件中心的端部。每个翼片能够在关闭位置和打开位置之间移动。

4. 发明申请

WO2010144637A1 INTEGRATED SOLAR PHOTOVOLTAIC AC MODULE 审中-公开
标题翻译：集成太阳能光伏交流模块
公开(公告)号：WO2010144637A1
公开(公告)日：2010-12-16
申请号：PCT/US2010/038057
申请日：2010-06-09
申请人： SOLAR INFRA, INC. , ALSTON, William, W. , MOSS, S., Elise , HOLMBERG, Stephen, P. , HOLMBERG, Larry, C.
发明人： ALSTON, William, W. , MOSS, S., Elise , HOLMBERG, Stephen, P. , HOLMBERG, Larry, C.
IPC分类号： H01L25/00
CPC分类号： H05K7/1432 , H02M7/003 , H02S30/10 , H02S40/32 , Y02E10/56
摘要： An integrated solar photovoltaic AC module and related methods are described in which the positional, mechanical, and thermal relationships among a micro-inverter, a solar panel body, and a mounting frame are optimized such that an advantageous combination of mechanical integrity, thermal stability, and durability is provided, while also keeping overall system costs down, keeping overall system weight low, and providing a clean visual look. In one preferred embodiment, the micro-inverter is mounted underneath the solar panel body on a plate member or flange member that extends between two or more side rails of a supporting frame of the solar panel body. An air gap is maintained between the micro-inverter and the solar panel body sufficient to inhibit thermal crosstalk therebetween. The plate or flange member is securably affixed to the two or more side rails of the frame in a manner that enhances lateral shear stability of the frame.
摘要翻译：描述了一种集成的太阳能光伏交流模块及相关方法，其中微逆变器，太阳能电池板主体和安装框架之间的位置，机械和热关系被优化，使得机械完整性，热稳定性，并提供耐用性，同时保持整体系统成本降低，保持整体系统重量低，并提供清洁的视觉外观。在一个优选实施例中，微逆变器安装在太阳能电池板主体下面的板件或凸缘部件上，该板件或凸缘部件在太阳能电池板主体的支撑框架的两个或更多个侧轨之间延伸。在微逆变器和太阳能电池板体之间保持足够的空气间隙，以防止它们之间的热串扰。板或凸缘构件以增强框架的横向剪切稳定性的方式牢固地固定到框架的两个或更多个侧轨。

5. 发明申请

WO2003057564A1 APPARATUS AND METHOD FOR SEALING CAVITIES 审中-公开
标题翻译：装置和方法密封CAVITIES
公开(公告)号：WO2003057564A1
公开(公告)日：2003-07-17
申请号：PCT/US2002/038922
申请日：2002-11-20
申请人： NEKTAR THERAPEUTICS , RASMUSSEN, Dennis, R. , SCHULER, Carlos, E. , ALSTON, William, W.
发明人： SCHULER, Carlos, E. , ALSTON, William, W.
IPC分类号： B65B7/16
CPC分类号： B65B7/2878 , B65B7/164 , B65B51/16
摘要： An apparatus is provided for sealing a first layer (150) to a second layer (130), the second layer comprising one or more cavities (135) adapted to contain a pharmaceutical formulation. The apparatus comprises a roller (110) comprising a heating element (125), and a surface (1159) adapted to support the first and second layers, the surface being translatable relative to the roller. The first layer is heat sealed to the second layer when contacted by the roller to contain the pharmaceutical formulation within the one or more cavities.
摘要翻译：提供了用于将第一层（150）密封到第二层（130）的装置，所述第二层包括适于容纳药物制剂的一个或多个空腔（135）。该装置包括一个包括加热元件（125）的辊子（110）和适于支撑第一和第二层的表面（1159），该表面可相对于辊子平移。当与辊接触时，第一层被热密封到第二层，以在一个或多个空腔内容纳药物制剂。

6. 发明申请

WO2005048982A2 INTRODUCING AEROSOL INTO A VENTILATOR CIRCUIT 审中-公开
标题翻译：将气溶胶引入通风机电路
公开(公告)号：WO2005048982A2
公开(公告)日：2005-06-02
申请号：PCT/US2004/038503
申请日：2004-11-17
申请人： NEKTAR THERAPEUTICS , ALSTON, William, W. , DWIVEDI, Saravajna, K. , TUCKER, Guy, V.
发明人： ALSTON, William, W. , DWIVEDI, Saravajna, K. , TUCKER, Guy, V.
IPC分类号： A61K9/00
CPC分类号： A61M11/00 , A61K31/7036 , A61M11/005 , A61M15/00 , A61M16/0009 , A61M16/08 , A61M16/0816 , A61M16/0825 , A61M16/0833 , A61M16/14 , A61M16/147 , A61M16/20 , A61M16/204 , A61M16/208 , A61M2016/0036
摘要： An aerosol introducer is provided for introducing an aerosolized pharmaceutical formulation into a ventilator circuit. The ventilator circuit comprises an endotracheal tube, an inhalation line extending from a ventilator, and an exhalation line extending from the ventilator. The aerosol introducer comprises a first end connectable to the inhalation line and the exhalation line; a second end connectable to the endotracheal tube; a first channel extending from the first end to the second end; a second channel extending from the first end to the second end; an inlet in the first channel, the inlet being adapted to receive an aerosolized pharmaceutical formulation; and a valving mechanism comprising one or more valves that reduce the loss of aerosolized pharmaceutical formulation to the exhalation line.
摘要翻译：提供了一种气溶胶导引器，用于将雾化的药物制剂引入呼吸机回路中。呼吸机回路包括气管插管，从呼吸机延伸的吸入管和从呼吸机延伸的呼气管。气溶胶导引器包括可连接到吸入管线和呼气管线的第一端口; 可连接到气管内管的第二端; 从第一端延伸到第二端的第一通道; 从所述第一端延伸到所述第二端的第二通道; 第一通道中的入口，入口适于接收雾化的药物制剂; 以及阀机构，其包括一个或多个阀，其减少雾化药物制剂对呼气管线的损失。

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