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1. 发明申请

WO2010010545A1 CLOT CAPTURE SYSTEMS AND ASSOCIATED METHODS 审中-公开
标题翻译：收集系统和相关方法
公开(公告)号：WO2010010545A1
公开(公告)日：2010-01-28
申请号：PCT/IE2009/000051
申请日：2009-07-22
申请人： NEURAVI LIMITED , BRADY, Eamon , RAZAVI, Mahmood , VALE, David , O'SHAUGHNESSY, John
发明人： BRADY, Eamon , RAZAVI, Mahmood , VALE, David , O'SHAUGHNESSY, John
IPC分类号： A61B17/221
CPC分类号： A61B17/221 , A61B17/22031 , A61B2017/00867 , A61B2017/22035 , A61B2017/22038 , A61B2017/22051 , A61B2017/22094 , A61B2017/2212 , A61B2017/2215 , A61B2017/2217 , A61F2/01 , A61F2230/0008 , A61F2230/001 , A61F2230/005 , A61F2230/0058
摘要： A clot capture system for disengaging a clot 2001 from a vessel wall 2002 and removing the clot 2001 from the vessel 202, comprises a clot capture device 2140 for placement on a distal side of a clot 2001. The clot capture device 2140 has a retracted delivery configuration and an expanded deployed configuration. The clot removal device has a proximal support frame 2012, and a distal fibre net 2130. The support frame 2012 has a retracted delivery configuration and an expanded deployed configuration. The proximal support frame 2012 in the expanded configuration defines a proximal inlet mouth for engaging a clot 2001 and a net 2130 for confining the clot 2001. An elongate member facilitates capture and/or withdrawal of a clot 2001 from a vessel 2002. The system also comprises a clot debonding device 2091 for placement on a proximal side of a clot 2001. The clot debonding device 2091 has a retracted delivery configuration and an expanded deployed configuration and comprises a clot engagement element 2112 which defines a distal abutment in the deployed configuration for urging a clot 2001 into the clot capture device 2140.
摘要翻译：用于使凝块2001与血管壁2002分离并从血管202移除血块2001的血块捕获系统包括用于放置在凝块2001的远侧上的凝块捕获装置2140.凝块捕获装置2140具有缩回的输送配置和扩展部署配置。凝块移除装置具有近端支撑框架2012和远端纤维网2130.支撑框架2012具有缩回的输送构型和扩张的展开构型。处于扩展构型的近端支撑框架2012限定了用于接合凝块2001的近端入口和用于限制凝块2001的网2130.细长构件有利于从血管2002捕获和/或撤出凝块2001.系统还包括用于放置在凝块2001的近侧的凝块剥离装置2091.凝块脱粘装置2091具有缩回的输送构型和扩张的展开构型，并且包括凝块接合元件2112，其在展开构型中限定了远端邻接件，用于推动凝块2001进入血块捕获装置2140。

2. 发明申请

WO2012052982A1 CLOT ENGAGEMENT AND REMOVAL SYSTEM 审中-公开
标题翻译：衣服接合和拆卸系统
公开(公告)号：WO2012052982A1
公开(公告)日：2012-04-26
申请号：PCT/IE2011/000057
申请日：2011-10-21
申请人： NEURAVI LIMITED , BRADY, Eamon , GILVARRY, Michael , RAZAVI, Mahmood K. , VALE, David
发明人： BRADY, Eamon , GILVARRY, Michael , RAZAVI, Mahmood K. , VALE, David
IPC分类号： A61B17/221
CPC分类号： A61B17/221 , A61B2017/22034 , A61B2017/22094 , A61B2017/2212 , A61B2017/2217
摘要： A clot retrieval apparatus 1 comprise a clot engaging device 2 and a capture basket 3. The clot engaging device 2 has a collapsed delivery configuration and an expanded deployment configuration. The clot engaging device has a proximal end and a distal end and an elongate body between the proximal end and the distal end. The capture basket 3 has a collapsed delivery configuration and an expanded deployment configuration. The capture basket 3 has a proximal mouth which is open when the capture basket 3 is in the deployed configuration. The clot engaging device 2 is axially movable relative to the capture basket for capture of a clot
摘要翻译：凝块取出装置1包括凝块接合装置2和捕获篮3.凝块接合装置2具有折叠的输送配置和扩展的展开构造。凝块接合装置具有近端和远端以及在近端和远端之间的细长主体。捕获篮3具有折叠的传送配置和扩展的部署配置。捕获筐3具有当捕获筐3处于展开构型时打开的近端口。凝块接合装置2可相对于捕获篮轴向移动以捕获凝块

3. 发明申请

WO2012120490A2 A CLOT RETRIEVAL DEVICE FOR REMOVING OCCLUSIVE CLOT FROM A BLOOD VESSEL 审中-公开
标题翻译：一种用于从血管中去除闭塞血栓的血液回收装置
公开(公告)号：WO2012120490A2
公开(公告)日：2012-09-13
申请号：PCT/IE2012/000011
申请日：2012-03-09
申请人： NEURAVI LIMITED , BRADY, Eamon , GILVARRY, Michael , RAZAVI, Mahmood , VALE, David , GRIFFIN, Patrick , CASEY, Brendan , MCNAMARA, Jason
发明人： BRADY, Eamon , GILVARRY, Michael , RAZAVI, Mahmood , VALE, David , GRIFFIN, Patrick , CASEY, Brendan , MCNAMARA, Jason
IPC分类号： A61B17/221 , A61F2/01
CPC分类号： A61B17/221 , A61B17/22031 , A61B17/320725 , A61B2017/00292 , A61B2017/00526 , A61B2017/00867 , A61B2017/22034 , A61B2017/22094 , A61B2017/2212 , A61B2017/2215 , A61F2/013 , A61F2002/011 , A61F2002/016 , A61F2002/018 , A61F2230/0069 , A61F2230/008 , A61F2230/0091 , A61F2230/0093
摘要： A clot retrieval device (9501) for removing occlusive clot from a blood vessel comprises an inner elongate body (9503) and an outer elongate body (9504) at least partially overlying the inner elongate body (9503). The device also comprises an elongate member or shaft (9502) having a proximal end which extends exterior of a patient so that a user can retrieve the stent-basket device and captured clot by retracting the shaft (9502). The outer elongate body (9504) and the inner elongate body (9503) are connected to the distal end of the shaft (9502) and are expandable relative to the shaft (9502) from a collapsed delivery configuration to an expanded deployed configuration. The outer elongate body (9504) is expandable relative to the inner elongate body (9503) to a radial extent which is greater than the radial extent of the inner body (9503) in the deployed configuration. The stent-basket construction of the device creates a reception space (9507) between the inner (9503) and outer (9504) to receive the target clot. The outer body (9504) is configured to allow as much as possible of the clot to migrate through it into the internal reception space (9507). Housing the clot in this reception space rather than pinning it to the wall of the vessel means that the clot is under less compression and can thus be retracted at a lower force. The inner elongate body (9503) and a distal capture net (9505) protect the distal vascular bed from embolisation.
摘要翻译：用于从血管移除闭塞凝块的凝块取出装置（9501）包括内部细长主体（9503）和至少部分地覆盖内部细长主体（9503）的外部细长主体（9504）。该装置还包括细长构件或轴（9502），该细长构件或轴具有延伸到患者外部的近端，使得使用者可以通过缩回轴（9502）来取回支架篮装置并捕获凝块。外部细长主体（9504）和内部细长主体（9503）连接到轴（9502）的远端并且可相对于轴（9502）从塌缩的递送构造扩展到展开的展开构造。外部细长主体（9504）可相对于内部细长主体（9503）膨胀至比展开构造中的内部主体（9503）的径向范围更大的径向范围。装置的支架篮构造在内部（9503）和外部（9504）之间形成接收空间（9507）以接收目标血块。外体（9504）被构造成尽可能允许凝块通过它进入内部接收空间（9507）。将血块容纳在该接收空间中而不是将其固定在血管壁上意味着血块处于较小的压缩下，因此可以以较小的力收回。内部细长体（9503）和远端捕获网（9505）保护远端血管床免受栓塞。

4. 发明申请

WO2011135556A1 CLOT ENGAGEMENT AND REMOVAL SYSTEMS 审中-公开
标题翻译：衣服接合和拆卸系统
公开(公告)号：WO2011135556A1
公开(公告)日：2011-11-03
申请号：PCT/IE2011/000026
申请日：2011-04-28
申请人： NEURAVI LIMITED , BRADY, Eamon , VALE, David , GILVARRY, Michael , MAHMOOD, Razavi
发明人： BRADY, Eamon , VALE, David , GILVARRY, Michael , MAHMOOD, Razavi
IPC分类号： A61B17/221
CPC分类号： A61F2/01 , A61B17/221 , A61B17/32056 , A61B2017/00287 , A61B2017/2212
摘要： A device for the removal of clot obstructing the flow of blood through an arterial vessel comprises an elongate member, a clot engaging element and a capture basket. The elongate member extends in use from a point adjacent a target treatment site interior of the patient to a point exterior of the patient. The capture basket comprises a frame and a net, and has an expanded and a collapsed configuration. The clot engaging element comprises a plurality of struts having an expanded and a collapsed configuration. The plurality of struts form a first section and a second section, the first section tapering outward and distally from the elongate member and connected to the second section. The second section comprises a plurality of cells defined by a plurality of struts and arranged around at least a portion of the circumference of an axis substantially parallel to that of the elongate member. The clot engaging element and the capture basket are restrained in the collapsed configuration for delivery to the target site. The clot engaging element is located adjacent the distal end of the elongate member and proximal of the capture basket.
摘要翻译：用于去除阻塞血液通过动脉血管的血块的装置包括细长构件，凝块接合元件和捕获篮。细长构件在使用中从邻近患者的目标治疗部位内部的点延伸到患者外部的点。捕获篮包括框架和网，并且具有展开和折叠构造。凝块接合元件包括具有膨胀和收缩构型的多个支柱。所述多个支柱形成第一部分和第二部分，所述第一部分从所述细长部件向外和远端逐渐变细并连接到所述第二部分。第二部分包括由多个支柱限定并且围绕基本上平行于细长构件的轴线的圆周的至少一部分布置的多个单元。凝块接合元件和捕获筐被限制在折叠构型中以输送到目标位置。凝块接合元件位于细长构件的远端和捕获篮的近侧附近。

5. 发明申请

WO2003094790A2 AN EMBOLIC PROTECTION SYSTEM 审中-公开
标题翻译：防爆保护系统
公开(公告)号：WO2003094790A2
公开(公告)日：2003-11-20
申请号：PCT/IE2003/000072
申请日：2003-05-13
申请人： SALVIAC LIMITED , BRADY, Eamon , TAYLOR, Charles , GRIFFIN, Patrick , CASEY, Brendan , VALE, David , GILSON, Paul , O'SHAUGHNESSY, John
发明人： BRADY, Eamon , TAYLOR, Charles , GRIFFIN, Patrick , CASEY, Brendan , VALE, David , GILSON, Paul , O'SHAUGHNESSY, John
IPC分类号： A61F2/01
CPC分类号： A61F2/013 , A61F2/95 , A61F2002/011 , A61F2002/018 , A61F2210/0057 , A61F2230/0006 , A61F2230/005 , A61F2230/0084 , A61F2250/0019
摘要： A catheter system (1) has an internal reception space for an embolic protection filter (10) to enable the filter (10) to be transported through a vasculature (20) and a treatment means such as a stent (15) to facilitate treatment. The catheter system may, in some configurations be used for retrieval of a filter (10) and stenting of a lesion with a stent (15). The procedure may also involve post dilitation using an on-board balloon (16).
摘要翻译：导管系统（1）具有用于栓塞保护过滤器（10）的内部接收空间，以使过滤器（10）能够通过脉管系统（20）和诸如支架（15）的治疗装置输送以便于治疗。在一些配置中，导管系统可以用于取出过滤器（10）和用支架（15）进行病变支架置入。该程序还可以包括使用车载气囊（16）进行后扩散。

6. 发明申请

WO2003094790A3 CATHETER SYSTEM WITH PROCEDURAL CATHETER AND EMBOLIC PROCTECTION SYSTEM 审中-公开
公开(公告)号：WO2003094790A3
公开(公告)日：2003-11-20
申请号：PCT/IE2003/000072
申请日：2003-05-13
申请人： SALVIAC LIMITED , BRADY, Eamon , TAYLOR, Charles , GRIFFIN, Patrick , CASEY, Brendan , VALE, David , GILSON, Paul , O'SHAUGHNESSY, John
发明人： BRADY, Eamon , TAYLOR, Charles , GRIFFIN, Patrick , CASEY, Brendan , VALE, David , GILSON, Paul , O'SHAUGHNESSY, John
IPC分类号： A61F2/01
摘要： A catheter system (1) has an internal reception space for an embolic protection filter (10) to enable the filter (10) to be transported through a vasculature (20) and a treatment means such as a stent (15) to facilitate treatment. The catheter system may, in some configurations be used for retrieval of a filter (10) and stenting of a lesion with a stent (15). The procedure may also involve post dilitation using an on-board balloon (16).

7. 发明申请

WO2003055413A3 A SUPPORT FRAME FOR AN EMBOLIC PROTECTION DEVICE 审中-公开
公开(公告)号：WO2003055413A3
公开(公告)日：2003-07-10
申请号：PCT/IE2002/000175
申请日：2002-12-23
申请人： SALVIAC LIMITED , BRADY, Eamon , VALE, David , KELLY, Ronald , NEILAN, John , HORAN, Steven , RABITTE, Gerard , MCCAFFREY, Gerry
发明人： BRADY, Eamon , VALE, David , KELLY, Ronald , NEILAN, John , HORAN, Steven , RABITTE, Gerard , MCCAFFREY, Gerry
IPC分类号： A61F2/01
摘要： A support (103) for an embolic protection device comprises round wires (116) which may form one or more support hoops for a filter body. The circumferential hoop formed by the wires (116) ensures that in the expanded position, the filter body (102) will be supported by the support frame (103) in circumferential apposition with the interior wall of the vasculature. The wires (116) may have a strain distributing linkage element in the form of a loop (120) in. The loop (120) acts as a diameter or circumference adjuster allowing an embolic protection device to adapt to different vessel contours and sizes whilst maintaining apposition with the vessel wall. The strain relieving geometry of the loops enhances the compliance of the bend points without creating a weakened hinge point, thus ensuring that there is no discontinuity in the circumferential seal against the vessel wall.

8. 发明申请

WO2003055412A2 A SUPPORT FRAME FOR AN EMBOLIC PROTECTION DEVICE 审中-公开
标题翻译：用于防爆装置的支撑框架
公开(公告)号：WO2003055412A2
公开(公告)日：2003-07-10
申请号：PCT/IE2002/000174
申请日：2002-12-23
申请人： SALVIAC LIMITED , BRADY, Eamon , VALE, David , KELLY, Ronald , NEILAN, John , HORAN, Steven , RABITTE, Gerard , MCCAFFREY, Gerry
发明人： BRADY, Eamon , VALE, David , KELLY, Ronald , NEILAN, John , HORAN, Steven , RABITTE, Gerard , MCCAFFREY, Gerry
IPC分类号： A61F2/06
CPC分类号： A61F2/013 , A61B2017/2212 , A61B2017/2215 , A61F2002/016 , A61F2002/018 , A61F2230/0067 , A61F2230/0093
摘要： An embolic protection device comprises a collapsible filter element for delivery through a vascular system of a patient. The filter element comprises a collapsible filter body (2) and a filter support (3) for the filter body. The filter body has an inlet end (4) and an outlet and (5), the inlet end (4) of the filter body has one or more inlet openings (6) sized to allow blood and embolic material enter the filter body (2) and the outlet end (5) of the filter body has a plurality of outlet openings (107) sized to allow through passage of blood but to retain undesired embolic material within the filter body (2). The filter support (3) is movable between a collapsed position for movement through the vascular system, and an extended outwardly projecting position to support the filter body in an expanded position. The filter support (3) comprises a generally tubular support frame defined by at least one wire (16).
摘要翻译：栓塞保护装置包括用于通过患者的血管系统递送的可折叠过滤器元件。过滤元件包括可折叠过滤器主体（2）和用于过滤器主体的过滤器支撑件（3）。过滤器本体具有入口端（4）和出口（5），过滤体的入口端（4）具有一个或多个入口开口（6），其尺寸允许血液和栓塞材料进入过滤体（2 ），并且过滤器主体的出口端（5）具有多个出口开口（107），其尺寸允许通过血液通过，但是将不期望的栓塞材料保持在过滤器主体（2）内。过滤器支撑件（3）可以在通过血管系统运动的折叠位置和延伸向外突出的位置之间移动，以将过滤器主体支撑在扩张位置。过滤器支撑件（3）包括由至少一根线（16）限定的大体上管状的支撑框架。

9. 发明申请

WO2003002019A2 A CATHETER 审中-公开
公开(公告)号：WO2003002019A2
公开(公告)日：2003-01-09
申请号：PCT/IE2002/000089
申请日：2002-06-27
申请人： SALVIAC LIMITED , BRADY, Eamon , NEILAN, John , VALE, David
发明人： BRADY, Eamon , NEILAN, John , VALE, David
IPC分类号： A61F
CPC分类号： A61F2/95 , A61F2/013 , A61F2002/011 , A61F2002/9517 , A61F2002/9528 , A61F2230/0006 , A61F2230/0008

10. 发明申请

WO2006111945A2 A RETRIEVAL CATHETER 审中-公开
标题翻译：检索针
公开(公告)号：WO2006111945A2
公开(公告)日：2006-10-26
申请号：PCT/IE2006/000036
申请日：2006-04-18
申请人： SALVIAC LIMITED , FAHEY, Gary , KELLY, Ronald , GRIFFIN, Patrick , BRADY, Eamon , VALE, David , NEILAN, John
发明人： FAHEY, Gary , KELLY, Ronald , GRIFFIN, Patrick , BRADY, Eamon , VALE, David , NEILAN, John
IPC分类号： A61F2/01 , A61B17/22 , A61M25/00
CPC分类号： A61L29/18 , A61B17/22031 , A61B17/221 , A61B90/39 , A61B2017/22035 , A61B2017/2215 , A61F2002/011
摘要： A retrieval catheter (200) comprises a catheter shaft (2) and a retrieval catheter tip at the distal end of the shaft (2). The tip comprises an expandable tip body (201) and two reinforcement columns (6, 7) extending along the tip body (201) embedded within the tip body (201). The tip body (201) comprises a stiff, distal, radiopaque segment (203) and a soft, proximal segment (202). The distal segment (203) has a distal nose part (205) extending distally of the reinforcement columns (6, 7). Along the distal nose part (205), the wall thickness of the tip body (201) tapers distally from a smaller wall thickness to a larger wall thickness, and the internal diameter tapers distally from a larger diameter to a smaller diameter.
摘要翻译：回收导管（200）包括在轴（2）的远端处的导管轴（2）和取回导管尖端。所述尖端包括可扩展尖端体（201）和沿着嵌入在所述尖端体（201）内的所述尖端体（201）延伸的两个加强柱（6,7）。尖端体（201）包括刚性的，远端的不透射线段（203）和柔软的近侧段（202）。远端段（203）具有远端加强柱（6,7）延伸的远端部分（205）。沿着远端鼻部（205），顶端体（201）的壁厚从较小的壁厚向远端逐渐变细到更大的壁厚，并且内径从较大的直径向远端逐渐变细到较小的直径。

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