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1. 发明申请

WO2009002849A2 FLUID CONCENTRATOR, AUTOLOGOUS CONCENTRATED BODY FLUIDS, AND USES THEREOF 审中-公开
标题翻译：流体浓缩器，自动浓缩体液，及其用途
公开(公告)号：WO2009002849A2
公开(公告)日：2008-12-31
申请号：PCT/US2008/067677
申请日：2008-06-20
申请人： MILLENNIUM MEDICAL TECHNOLOGIES, INC. , KYLE, Matthew, R. , COULL, Thomas
发明人： KYLE, Matthew, R. , COULL, Thomas
IPC分类号： A61M1/02 , A61M1/34 , B01D21/00 , B04B1/00 , A61K35/12 , A61M1/36
CPC分类号： A61M1/3633 , A61K35/14 , A61K35/16 , A61K35/28 , A61K35/30 , A61K35/32 , A61K35/38 , A61K35/50 , A61K35/52 , A61M1/262 , A61M1/34 , A61M1/3693 , A61M1/3696 , A61M2202/0405 , A61M2202/0413 , A61M2202/0415 , A61M2202/0464 , A61M2202/0466 , A61M2202/0496 , A61M2202/07 , A61M2202/09 , A61M2202/10 , A61M2205/3306 , A61M2205/3331 , A61M2205/75 , B01D15/3809 , B01D15/3828 , B01D21/0012 , B01D21/262 , B01D21/34 , B01D24/007 , B01D24/10 , B01D61/246 , B01D63/02 , B01D65/00 , B01D2221/10 , B01D2313/10 , B01D2313/243 , B01D2313/50 , B01D2313/90 , B04B1/00 , B04B5/04 , B04B2005/0478
摘要： The present invention provides devices and methods for concentrating a fluid and for treating a patient with the concentrated fluid. The concentrator apparatus includes a main housing defining a separation chamber, a filter housing containing a filter comprising a filter element, a piping for moving concentrated fluid from the separation chamber to the filter, and ports for pressurizing the concentrated fluid past the filter element of the filter. The present invention also provides a variety of uses of concentrated body fluids, including autologous concentrated body fluid. The concentrated fluids can be used for example in surgical applications, including graft applications such as allograft, xenograft and autograft applications.
摘要翻译：本发明提供了用于浓缩流体和用于用浓缩流体治疗患者的装置和方法。集中装置包括限定分离室的主壳体，容纳包括过滤元件的过滤器的过滤器壳体，用于将浓缩流体从分离室移动到过滤器的管道，以及用于将浓缩流体加压通过过滤元件的过滤元件过滤。本发明还提供了包括自体浓缩体液在内的浓缩体液的各种用途。浓缩流体可用于例如外科应用，包括移植物应用，如同种异体移植物，异种移植物和自体移植物应用。

2. 发明申请

WO2009031990A1 FLUID CONCENTRATOR 审中-公开
标题翻译：流体浓缩器
公开(公告)号：WO2009031990A1
公开(公告)日：2009-03-12
申请号：PCT/US2005/013385
申请日：2005-04-20
申请人： MILLENNIUM MEDICAL TECHNOLOGIES, INC. , COULL, Thomas , KYLE, Matthew , KIDDER, Louis, S.
发明人： COULL, Thomas , KYLE, Matthew , KIDDER, Louis, S.
IPC分类号： B04B7/16 , B04B7/18
CPC分类号： B04B1/00 , A61M1/262 , A61M1/3496 , A61M1/3693 , B04B5/04 , B04B2005/0478
摘要： A concentrator (10) is used for concentrating a fluid, particularly a plasma component out of blood, for treatment of a patient. The concentrator apparatus (10) includes a main housing (12) defining a centrifuge chamber ( 14), that also holds the filter (38). The concentrator (10) allows viewing of the fluid after centrifuging, with an outlet port (32) positionable at a height corresponding to the level of the fraction of the fluid to be further concentrated. Once the fluid is centrifuged, a portion of the fluid is drawn through the outlet (32), and then pressured past the filter (38) to further concentrate the fluid using the same vessel (10) as used for centrifuging. The same plunger (68) is preferably used to draw centrifuged fluid from the centrifuge chamber (14) as to pressure the centrifuged fluid past the filter (38).
摘要翻译：浓缩器（10）用于将流体，特别是血液中的血浆成分浓缩，用于治疗患者。集中器装置（10）包括限定离心机室（14）的主壳体（12），其也保持过滤器（38）。浓缩器（10）允许在离心之后观察流体，其中出口端口（32）可定位在与要进一步浓缩的流体的分数水平相对应的高度处。一旦流体被离心，一部分流体被抽出通过出口（32），然后压力通过过滤器（38），以进一步使用与用于离心的容器相同的容器（10）浓缩流体。优选地使用相同的柱塞（68）来从离心机室（14）中抽取离心的流体，以将离心的流体压力通过过滤器（38）。

3. 发明申请

WO2004045373A2 COMPRESSION BONE FRAGMENT WIRE 审中-公开
标题翻译：压缩骨折片
公开(公告)号：WO2004045373A2
公开(公告)日：2004-06-03
申请号：PCT/US2003/036420
申请日：2003-11-13
申请人： MILLENNIUM MEDICAL TECHNOLOGIES, INC.
发明人： WEINER, Lon, S. , COULL, Thomas
IPC分类号： A61B
CPC分类号： A61B17/685 , A61B17/8605 , A61B17/8665
摘要： A bone fragment wire (10) connects a bone fragment (30) to an anchor bone (32) for healing duration. The bone fragment wire (10) has a distal bone penetration section (22) which is advanced into the bone (20) and a proximal bone exterior section (24). The proximal bone exterior section (24) is longer than the bone penetration section (22), and thus extends substantially out of the bone (20) during healing of the bone (20). The bone penetration section (22) includes a distal bone anchor section (12) which threadingly engages the anchor bone (32), and a proximal fragment section (14) of small diameter. The fragment section (14) fits within the overbore created by advancing the bone anchor section (12) through the bone fragment (30), and thus extends through but does not positively engage the bone fragment (30). A compression engagement (36) on a distal end of the bone exterior section (24) provides a compression shoulder (38). In one embodiment the compression engagement (36) is provided by a threaded compression nut (40), while in another embodiment the compression engagement (36) is permanently affixed to the bone wire (10). The shoulder (38) makes substantial contact with an exterior surface of the bone fragment (30), biasing the bone fragment (30) towards the anchor bone (32) with a controlled compression force. The compression engagement (36) is further adapted, such as through thread from and/or with a sloped proximal side, to enable the bone wire (10) to be more easily removed from the healed fracture without damaging surrounding tissue.
摘要翻译：骨碎片线（10）将骨碎片（30）连接到锚骨（32），以愈合持续时间。骨碎片线（10）具有远端骨穿透部分（22），其进入骨骼（20）和近端骨外部部分（24）。近端骨外部部分（24）比骨穿透部分（22）长，并且因此在骨骼（20）的愈合期间基本上延伸出骨骼（20）。骨穿透部分（22）包括与锚骨（32）螺纹接合的远端骨锚部分（12）和小直径的近端碎片部分（14）。碎片部分（14）装配在通过使骨锚固部分（12）穿过骨碎片（30）前进而形成的穿孔中，并且因此延伸穿过但不能正确地接合骨碎片（30）。在骨外部部分（24）的远端上的压缩接合（36）提供压缩肩部（38）。在一个实施例中，压缩接合（36）由螺纹压缩螺母（40）提供，而在另一个实施例中，压缩接合（36）永久地固定到骨线（10）。肩部（38）与骨碎片（30）的外表面实质接触，以受控的压缩力将骨片（30）偏向锚骨（32）。压缩接合（36）还适于例如通过来自和/或具有倾斜近侧的螺纹，以使得骨线（10）能够更容易地从愈合的骨折移除而不损坏周围的组织。

4. 发明申请

WO2003101318A1 BONE FIXATOR WITH OUTRIGGER 审中-公开
标题翻译：骨头矫正器与外套
公开(公告)号：WO2003101318A1
公开(公告)日：2003-12-11
申请号：PCT/US2003/016593
申请日：2003-05-28
申请人： MILLENNIUM MEDICAL TECHNOLOGIES, INC.
发明人： WEINER, Lon, S. , COULL, Thomas
IPC分类号： A61B17/60
CPC分类号： A61B17/6425
摘要： An external fixator (10) includes a main body (12) and an outrigger (14) for extending over a fractured joint, such as a wrist joint. The main body (12) can be positioned next to a right arm, or flipped over and positioned next to a left arm. The outrigger (14) is attachable to extend either to the left or to the right of the main body (12), as appropriate. A distal body is removeably connectable to the distal end of the main body (12), and the the distal body can be affixed to bone on the opposite side of the fracture to immobilize the joint where the fracture occurs. The distal body (18) is connected to the main body (12) with an adjustable securement section which provides six degrees of adjustment freedom. The outrigger (14) is attached to the main body (12) through a slide plate in a dual rail configuration which provides two dimensions of adjustment. Fragment pin supports (24) ride in a track (98) of the outrigger (14) , and provide seven degrees of adjustment freedom for directed fixation of fragments at the fracture site. The outrigger (14) is pivotally adjustable relative to the main body (12), and includes track portions (98) separated by a wrap around angle. The major components of the fixator are molded of plastic. A surgical technique using the fixator (10) includes immobilizing the joint for an initial healing duration and retaining fragment pins in place during a secondary healing duration.
摘要翻译：外固定器（10）包括用于在诸如腕关节之类的断裂关节上延伸的主体（12）和外伸支架（14）。主体（12）可以位于右臂旁边，或翻转并位于左臂旁边。外伸支架（14）可适当地延伸至主体（12）的左侧或右侧。远侧主体可移除地连接到主体（12）的远端，并且远端本体可以固定在骨折的相对侧上的骨上，以固定发生骨折的关节。远端主体（18）通过可调节的固定部分连接到主体（12），该固定部分提供六度的调节自由度。外伸支架（14）通过双轨配置的滑板连接到主体（12），双轨配置提供两个调节尺寸。碎片销支撑（24）骑在外伸支架（14）的轨道（98）中，并且提供七度的调节自由度，用于在骨折部位定向固定碎片。支腿（14）相对于主体（12）可枢转地调节，并且包括由卷绕角度分开的轨道部分（98）。固定器的主要部件由塑料模制。使用固定器（10）的手术技术包括固定关节以达到初始愈合时间，并且在二次愈合期间将碎片销保持在适当位置。

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