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1. 发明申请

WO2005042067A8 Wet/dry automatic injector assembly 审中-公开
标题翻译：湿/干自动注射器组件
公开(公告)号：WO2005042067A8
公开(公告)日：2006-06-15
申请号：PCT/US2004034556
申请日：2004-10-21
申请人： MERIDIAN MEDICAL TECHNOLOGIES , GRIFFITHS STEVEN M , HILL ROBERT L , WILMOT JOHN G
发明人： GRIFFITHS STEVEN M , HILL ROBERT L , WILMOT JOHN G
IPC分类号： A61M5/20 , A61M5/28 , A61M5/31 , A61M5/32 , A61M5/34
CPC分类号： A61M5/31596 , A61M5/19 , A61M5/2033 , A61M5/2066 , A61M5/284 , A61M5/286 , A61M5/3145 , A61M5/31513 , A61M5/3202 , A61M5/3293 , A61M5/34 , A61M5/343 , A61M5/348 , A61M2005/206 , A61M2005/2073 , A61M2005/287 , A61M2005/3106 , A61M2005/3131 , A61M2005/3132 , A61M2202/064 , A61M2205/7536 , A61M2205/7545
摘要： An automatic medicament injector having a compartment for a dry medicament component and a compartment for a wet medicament component. The two compartments are separated by a seal structure that has a plug that is moved from a sealing position into a mixing position when the device is activated. The seal structure includes a wiper that scrapes the interior walls in the dry component compartment to prevent the dry component from accumulating at the seal/glass interface. A tapered insert "funnels" the mixed medicament components to an attached needle assembly, but can be removed when the device is filled. A filter is provided between the medicament compartments and the needle assembly. A chamber between the filter and the needle assembly allows for better flow through the filter. An actuation assembly drives the plug into the mixing position and forces the mixed medicament through the needle and into the user.
摘要翻译：一种自动药物注射器，其具有用于干药物组分的隔室和用于湿药物组分的隔室。两个隔室由密封结构分开，该密封结构具有当该装置被启动时从密封位置移动到混合位置的塞子。密封结构包括擦拭干燥部件隔室中的内壁以防止干燥部件在密封/玻璃界面处积聚的刮水器。锥形插入件将混合的药物组分“漏出”到连接的针组件，但是当装置被填充时可以将其移除。在药剂隔室和针组件之间设置过滤器。过滤器和针组件之间的腔室允许更好地流过过滤器。致动组件将塞子驱动到混合位置，并迫使混合药物穿过针头并进入使用者。

2. 发明申请

WO2005042067A3 WET/DRY AUTOMATIC INJECTOR ASSEMBLY 审中-公开
标题翻译：湿/干自动注射器总成
公开(公告)号：WO2005042067A3
公开(公告)日：2005-10-06
申请号：PCT/US2004034556
申请日：2004-10-21
申请人： MERIDIAN MEDICAL TECHNOLOGIES , GRIFFITHS STEVEN M , HILL ROBERT L , WILMOT JOHN G
发明人： GRIFFITHS STEVEN M , HILL ROBERT L , WILMOT JOHN G
IPC分类号： A61M5/20 , A61M5/28 , A61M5/31 , A61M5/32 , A61M5/34
CPC分类号： A61M5/31596 , A61M5/19 , A61M5/2033 , A61M5/2066 , A61M5/284 , A61M5/286 , A61M5/3145 , A61M5/31513 , A61M5/3202 , A61M5/3293 , A61M5/34 , A61M5/343 , A61M5/348 , A61M2005/206 , A61M2005/2073 , A61M2005/287 , A61M2005/3106 , A61M2005/3131 , A61M2005/3132 , A61M2202/064 , A61M2205/7536 , A61M2205/7545
摘要： An automatic medicament injector having a compartment for a dry medicament component and a compartment for a wet medicament component. The two compartments are separated by a seal structure that has a plug that is moved from a sealing position into a mixing position when the device is activated. The seal structure includes a wiper that scrapes the interior walls in the dry component compartment to prevent the dry component from accumulating at the seal/glass interface. A tapered insert "funnels" the mixed medicament components to an attached needle assembly, but can be removed when the device is filled. A filter is provided between the medicament compartments and the needle assembly. A chamber between the filter and the needle assembly allows for better flow through the filter. An actuation assembly drives the plug into the mixing position and forces the mixed medicament through the needle and into the user.
摘要翻译：一种自动药物注射器，其具有用于干药物组分的隔室和用于湿药物组分的隔室。两个隔室由密封结构分开，该密封结构具有当该装置被启动时从密封位置移动到混合位置的塞子。密封结构包括擦拭干燥部件隔室中的内壁以防止干燥部件在密封/玻璃界面处积聚的刮水器。锥形插入件将混合的药物组分“漏出”到连接的针组件，但是当装置被填充时可以将其移除。在药剂隔室和针组件之间设置过滤器。过滤器和针组件之间的腔室允许更好地流过过滤器。致动组件将塞子驱动到混合位置，并迫使混合药物穿过针头并进入使用者。

3. 发明申请

WO2008048750A3 AUTOINJECTOR WITH NEEDLE DEPTH ADAPTER 审中-公开
标题翻译：带有针孔适配器的AUTOINJECTOR
公开(公告)号：WO2008048750A3
公开(公告)日：2008-07-17
申请号：PCT/US2007078106
申请日：2007-09-11
申请人： MERIDIAN MEDICAL TECHNOLOGIES , WILMOT JOHN G , HILL ROBERT L
发明人： WILMOT JOHN G , HILL ROBERT L
IPC分类号： A61M5/00
CPC分类号： A61M5/24 , A61M5/2033 , A61M5/3202 , A61M5/46 , A61M2005/206 , A61M2005/2073 , A61M2005/3143 , A61M2005/3267
摘要： An autoinjector (32) useful for, inter alia, providing an injection of liquid medicament is uniquely capable of providing injections, utilizes a needle depth adapter (40) to provide injection depths with a combination of accuracy and precision not heretofore seen. In addition, the autoinjector (32) with needle depth adapter (40) can include a variety of size needle depth adapters to provide an autoinjector of varying, precise injection depths and which can be readily and easily manufactured. The autoinjector (32) includes housing (34), cartridge assembly (36), needle (38), needle depth adapter (40), and power providing assembly (42).
摘要翻译：用于特别是提供液体药物注射的自动注射器（32）独特地能够提供注射，利用针深度适配器（40）以至少未见到的精度和精度的组合提供注射深度。此外，具有针深度适配器（40）的自动注射器（32）可以包括各种尺寸的针深度适配器，以提供具有各种精确的注射深度的自动注射器，并且可以容易且容易地制造。自动注射器（32）包括壳体（34），盒组件（36），针（38），针深度适配器（40）和功率提供组件（42）。

4. 发明申请

WO2008027382A3 VORTEX FEATURE FOR DRUG DELIVERY SYSTEM 审中-公开
标题翻译： VORTEX药物输送系统功能
公开(公告)号：WO2008027382A3
公开(公告)日：2008-06-26
申请号：PCT/US2007018920
申请日：2007-08-28
申请人： MERIDIAN MEDICAL TECHNOLOGIES , GRIFFITHS STEVEN M , HILL ROBERT L , ROBBEN MATTHEW P
发明人： GRIFFITHS STEVEN M , HILL ROBERT L , ROBBEN MATTHEW P
IPC分类号： A61M5/31
CPC分类号： A61M5/2066 , A61M5/2033 , A61M5/31596 , A61M2005/2013 , A61M2005/206 , A61M2005/2073
摘要： An automatic injector separately stores liquid and dry components in respective compartments. When the injector is activated, a fluid-directing member between the liquid and dry compartments causes the liquid component to form a vortex as the liquid flows into the dry compartment. This allows the two components to combine more thoroughly and quickly to form a liquid solution that is delivered to an injection site.
摘要翻译：自动注射器将液体和干燥部件分别存储在相应的隔室中。当喷射器被激活时，液体和干燥室之间的流体引导构件使液体组分在液体流入干燥室时形成涡流。这允许两个组分更彻底和快速地组合以形成被输送到注射部位的液体溶液。

5. 发明申请

WO2008140737A3 DRUG DELIVERY SYSTEM WITH A SMALL AMOUNT OF A THERAPEUTIC AGENT 审中-公开
标题翻译：具有小量治疗药物的药物递送系统
公开(公告)号：WO2008140737A3
公开(公告)日：2009-12-30
申请号：PCT/US2008005896
申请日：2008-05-08
申请人： MERIDIAN MEDICAL TECHNOLOGIES , GRIFFITHS STEVEN M , HILL ROBERT L , WANNARKA GERALD L
发明人： GRIFFITHS STEVEN M , HILL ROBERT L , WANNARKA GERALD L
IPC分类号： A61M37/00
CPC分类号： A61M5/2066 , A61M5/2033 , A61M5/284 , A61M5/286 , A61M5/3145 , A61M5/3202 , A61M5/3293 , A61M5/344 , A61M2005/206 , A61M2005/2073 , A61M2005/287 , A61M2005/3118
摘要： A drug delivery system includes an automatic injector that can deliver a small, precise amount of a therapeutic agent. The automatic injector includes a chamber for containing a liquid component and a thin porous member that carries thereon and/or therein the small, precise amount of therapeutic agent. Upon activation of the automatic injector, a flow path opens from the chamber through the porous member, enabling the liquid component to rapidly mix with the therapeutic agent before being injected.
摘要翻译：药物递送系统包括能够递送小量精确量的治疗剂的自动注射器。自动注射器包括用于容纳液体组分的室和在其上和/或其中载有小量精确量的治疗剂的薄多孔构件。在激活自动注射器时，流动通道通过多孔构件从腔室打开，使得液体组分能够在注射之前与治疗剂快速混合。

6. 发明申请

WO2006017732B1 AUTOMATIC INJECTOR 审中-公开
标题翻译：自动注射器
公开(公告)号：WO2006017732B1
公开(公告)日：2007-12-27
申请号：PCT/US2005027889
申请日：2005-08-04
申请人： MERIDIAN MEDICAL TECHNOLOGIES , YOUNG MATTHEW EGERTON , RAVEN SOPHIE REBECCA , MURPHY MARTIN JOSEPH , HURLSTONE CHRISTOPHER JOHN , DAINTREY JOSEPH WILLIAM , ROCHFORD CRAIG MALCOLM , KIRKWOOD STEPHEN PHILIP , MATHEWS COLIN JAMES , HILL ROBERT L , WILMOT JOHN GLYNDWR
发明人： YOUNG MATTHEW EGERTON , RAVEN SOPHIE REBECCA , MURPHY MARTIN JOSEPH , HURLSTONE CHRISTOPHER JOHN , DAINTREY JOSEPH WILLIAM , ROCHFORD CRAIG MALCOLM , KIRKWOOD STEPHEN PHILIP , MATHEWS COLIN JAMES , HILL ROBERT L , WILMOT JOHN GLYNDWR
IPC分类号： A61M5/00 , A61M5/32
CPC分类号： A61M5/3271 , A61M5/2033 , A61M5/2459 , A61M5/3129 , A61M5/31596 , A61M5/3245 , A61M5/326 , A61M2005/2013 , A61M2005/206 , A61M2005/2073 , A61M2005/3126 , A61M2005/3247 , A61M2205/586
摘要： An auto-injector for dispensing a predetermined dose of medicament is disclosed. The auto-injector includes a needle cover that is configured to move from a retracted position to an extended locked position. The auto-injector includes a first locking assembly to hold the needle cover in a locked retracted position and a second locking assembly to hold the needle cover in a locked extended position.
摘要翻译：公开了一种用于分配预定剂量的药物的自动注射器。自动注射器包括构造成从缩回位置移动到延伸锁定位置的针盖。自动注射器包括将针盖保持在锁定缩回位置的第一锁定组件和将针盖保持在锁定伸出位置的第二锁定组件。

7. 发明申请

WO2006017732A3 AUTOMATIC INJECTOR 审中-公开
标题翻译：自动注射器
公开(公告)号：WO2006017732A3
公开(公告)日：2007-11-08
申请号：PCT/US2005027889
申请日：2005-08-04
申请人： MERIDIAN MEDICAL TECHNOLOGIES , YOUNG MATTHEW EGERTON , RAVEN SOPHIE REBECCA , MURPHY MARTIN JOSEPH , HURLSTONE CHRISTOPHER JOHN , DAINTREY JOSEPH WILLIAM , ROCHFORD CRAIG MALCOLM , KIRKWOOD STEPHEN PHILIP , MATHEWS COLIN JAMES , HILL ROBERT L , WILMOT JOHN GLYNDWR
发明人： YOUNG MATTHEW EGERTON , RAVEN SOPHIE REBECCA , MURPHY MARTIN JOSEPH , HURLSTONE CHRISTOPHER JOHN , DAINTREY JOSEPH WILLIAM , ROCHFORD CRAIG MALCOLM , KIRKWOOD STEPHEN PHILIP , MATHEWS COLIN JAMES , HILL ROBERT L , WILMOT JOHN GLYNDWR
IPC分类号： A61M5/00 , A61M5/32
CPC分类号： A61M5/3271 , A61M5/2033 , A61M5/2459 , A61M5/3129 , A61M5/31596 , A61M5/3245 , A61M5/326 , A61M2005/2013 , A61M2005/206 , A61M2005/2073 , A61M2005/3126 , A61M2005/3247 , A61M2205/586
摘要： An auto-injector for dispensing a predetermined dose of medicament is disclosed. The auto-injector includes a needle cover that is configured to move from a retracted position to an extended locked position. The auto-injector includes a first locking assembly to hold the needle cover in a locked retracted position and a second locking assembly to hold the needle cover in a locked extended position.
摘要翻译：公开了一种用于分配预定剂量的药物的自动注射器。自动注射器包括构造成从缩回位置移动到延伸锁定位置的针盖。自动注射器包括第一锁定组件以将针盖保持在锁定的缩回位置，以及第二锁定组件以将针罩保持在锁定的延伸位置。

8. 发明申请

WO0230494A3 WET/DRY AUTOMATIC INJECTOR ASSEMBLY 审中-公开
标题翻译：湿/干燥自动注射器组件
公开(公告)号：WO0230494A3
公开(公告)日：2002-08-22
申请号：PCT/US0142595
申请日：2001-10-10
申请人： MERIDIAN MEDICAL TECHNOLOGIES
发明人： HILL ROBERT L , WILMOT JOHN G , GRIFFITHS STEVEN
IPC分类号： A61J1/05 , A61M5/20 , A61M5/28 , A61M5/31 , A61M5/32 , A61M5/34
CPC分类号： A61M5/34 , A61M5/2033 , A61M5/2066 , A61M5/286 , A61M5/3145 , A61M5/31538 , A61M5/343 , A61M2005/206 , A61M2005/2073 , A61M2005/3132
摘要： The present invention is directed to an automatic injection device containing a pre-loaded charge of medicament for automatically self-administering the medicament upon actuation thereof. The automatic injection device includes a housing assembly having an interior chamber, a filter assembly, an activation assembly and a needle assembly. In accordance with the present invention, the interior chamber may include a dry compartment for storing a predetermined dry charge of dry medicament therein, and a wet compartment for storing a predetermined amount of liquid injection solution therein. The filter assembly enhances the laminar flow of fluid between the wet compartment to the dry compartment prior to the pressurization of the liquid injection solution within the wet compartment.
摘要翻译：本发明涉及一种自动注射装置，该自动注射装置包含用于在启动药物时自动自我给药的药物的预先装载药量。自动注射装置包括具有内部腔室的壳体组件，过滤器组件，启动组件和针组件。根据本发明，内部腔室可以包括用于在其中存储预定干燥药剂的干燥隔室，以及用于在其中存储预定量的液体注射溶液的湿室。过滤器组件在湿腔室内的液体注射溶液加压之前增强了湿腔室与干腔室之间的流体层流。

9. 发明申请

WO9930759A3 AUTOMATIC INJECTOR FOR ADMINISTRATING A MEDICAMENT 审中-公开
标题翻译：自动注射器管理药物
公开(公告)号：WO9930759A3
公开(公告)日：1999-11-25
申请号：PCT/US9826666
申请日：1998-12-16
申请人： MERIDIAN MEDICAL TECHNOLOGIES
发明人： WILMONT JOHN G , MORTON JASON C , EDSALL DAVID R , PAGE JON P , CASTLEBERRY JEFFREY P , BOYD ROBERT R , KETCHAM CLIFF , GOLDBERG JEFFREY I , HILL ROBERT L
IPC分类号： A61M5/20 , A61M5/24 , A61M5/31 , A61M5/32
CPC分类号： A61M5/24 , A61M5/2033 , A61M5/3135 , A61M5/3202 , A61M5/3232 , A61M5/326 , A61M2005/206 , A61M2005/2073 , A61M2005/2407 , A61M2005/247 , A61M2005/2492 , A61M2005/3118
摘要： The present invention relates to an automatic injector having a drive assembly with an actuator extending from the rearward end portion of the housing and a removal resistant cover for preventing unintended operation of the actuator. The present invention also relates to a sealing arrangement wherein the needle is sealed within a sterilized needle chamber by at least three sealing members which cooperate to form the chamber. Also, the present invention relates to an injector in which the cartridge is mounted to a tubular cartridge mounting portion of the needle carrier with an annular sealing member disposed therebetween. The cartridge mounting portion has at least one generally axially extending groove which allows air to escape from the cartridge mounting portion as the cartridge is being moved forwardly to a medicament supplying position.
摘要翻译：本发明涉及一种具有驱动组件的自动喷射器，该驱动组件具有从壳体的后端部分延伸的致动器和用于防止致动器意外操作的防拆盖。本发明还涉及一种密封装置，其中针通过至少三个密封构件密封在灭菌的针室内，这些密封构件协作形成腔室。此外，本发明涉及一种注射器，其中药筒安装到针架的管状药筒安装部分，其间设置有环形密封件。盒安装部分具有至少一个大致轴向延伸的凹槽，当槽被向前移动到药物供应位置时，允许空气从盒安装部分逸出。

10. 发明申请

WO0230493A3 WET/DRY AUTOMATIC INJECTOR ASSEMBLY 审中-公开
标题翻译：湿/干燥自动注射器组件
公开(公告)号：WO0230493A3
公开(公告)日：2002-06-20
申请号：PCT/US0142594
申请日：2001-10-10
申请人： MERIDIAN MEDICAL TECHNOLOGIES
发明人： WILMOT JOHN G , HILL ROBERT L , WHITTIER JOHN
IPC分类号： A61J1/05 , A61M5/20 , A61M5/28 , A61M5/31 , A61M5/32 , A61M5/34
CPC分类号： A61M5/343 , A61M5/2033 , A61M5/2066 , A61M5/286 , A61M5/3145 , A61M5/34 , A61M2005/206 , A61M2005/2073
摘要： The present invention is directed to an automatic injection device containing a pre-loaded charge of medicament for automatically self-administering the medicament upon actuation thereof. The automatic injection device includes a housing assembly having an interior chamber, an activation assembly and a needle assembly for dispensing a dissolved medicament to a user. A dry compartment for storing a predetermined dry charge of dry medicament is located within the interior chamber. A wet compartment for storing a predetermined amount of liquid injection solution is also located within the interior chamber. A separation assembly separates the dry compartment from the wet compartment. The separation assembly prevents transfer of the liquid injection solution from the wet compartment to the dry compartment prior to activation of the automatic injection device. One or more medicament support assemblies located within the dry compartment prevent the passage of undissolved medicament from the dry compartment.
摘要翻译：本发明涉及一种自动注射装置，该自动注射装置包含用于在启动药物时自动自我给药的药物的预先装载药量。自动注射装置包括具有内部腔室的壳体组件，致动组件和用于将溶解药物分配给使用者的针组件。用于储存干燥药剂的预定干燥剂量的干燥室被设置在内部室内。用于存储预定量的液体注入溶液的湿室也位于内室内。分离组件将干燥室与湿室分开。分离组件在激活自动注射装置之前防止液体注射溶液从湿腔室转移到干腔室。位于干燥室内的一个或多个药物支撑组件防止未溶解的药物从干燥室通过。

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