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    • 6. 发明申请
    • FOLDOVER SENSORS AND METHODS FOR MAKING AND USING THEM
    • FOLDOVER传感器及其制造和使用方法
    • WO2013177573A3
    • 2014-07-10
    • PCT/US2013042763
    • 2013-05-24
    • MEDTRONIC MINIMED INCLITTLE MEGAN EWOLFE KATHERINE TRAGHAVENDHAR GAUTHAMLIANG BRADLEY CHISHAH RAJIV
    • LITTLE MEGAN EWOLFE KATHERINE TRAGHAVENDHAR GAUTHAMLIANG BRADLEY CHISHAH RAJIV
    • A61B5/1486
    • A61B5/14532A61B5/14865A61B2562/125A61B2562/166A61B2562/222C12Q1/001C12Q1/006G01N27/3272Y10T29/49204
    • The application disclosed herein includes implantable blood glucose sensors having three dimensional configurations that allow expansive "360°" sensing (i.e. sensing analyte from multiple directions) in the environments in which such sensors are disposed. Disclsed is an analyte sensor apparatus comprising: a base substrate comprising a planar sheet of a flexible material adapted to transition from a first configuration to a second configuration when the base substrate is folded to form a fixed bend; a working electrode, a counter electrode and a reference electrode disposed upon a first surface of the base substrate; a plurality of contact pads disposed upon the first surface of the base substrate; a plurality of electrical conduits disposed upon the first surface of the base substrate, wherein the plurality of electrical conduits are adapted to transmit electrical signals between electrodes and contact pads separated by the fixed bend; and an analyte sensing layer disposed over the working electrode, wherein the analyte sensing layer detectably alters the electrical current at the working electrode in the presence of an analyte; wherein: the base substrate comprises the fixed bend so as to form a configuration in which: at least one electrode is disposed on a first side of the fixed bend; and at least one electrode is disposed on a second side of the fixed bend.
    • 本文公开的应用包括具有三维结构的可植入血糖传感器,其允许在布置这些传感器的环境中进行膨胀的“360°”感测(即感测来自多个方向的分析物)。 分解物是分析物传感器装置,包括:基底基底,其包括柔性材料的平面片,所述平面片适于在所述基底基底被折叠以形成固定弯曲时从第一构型转变到第二构型; 工作电极,对置电极和设置在所述基底基板的第一表面上的参考电极; 设置在所述基底基板的第一表面上的多个接触焊盘; 多个电导管,其设置在所述基底基板的所述第一表面上,其中所述多个电导管适于在电极与由所述固定弯曲部分开的接触垫之间传输电信号; 以及分析物感测层,其设置在所述工作电极之上,其中所述分析物感测层在分析物的存在下可检测地改变所述工作电极处的电流; 其中:所述基底基板包括所述固定弯曲部,以便形成其中:至少一个电极设置在所述固定弯曲部的第一侧上; 并且至少一个电极设置在固定弯管的第二侧上。
    • 7. 发明申请
    • MULTI-CONDUCTOR LEAD CONFIGURATIONS USEFUL WITH MEDICAL DEVICE SYSTEMS AND METHODS FOR MAKING AND USING THEM
    • 具有医疗装置系统的多导体引线配置及其制造和使用方法
    • WO2011063259A3
    • 2011-08-04
    • PCT/US2010057474
    • 2010-11-19
    • MEDTRONIC MINIMED INCSHAH RAJIVGOTTLIEB REBECCA KWOLFE KATHERINE T
    • SHAH RAJIVGOTTLIEB REBECCA KWOLFE KATHERINE T
    • A61B5/145H01B7/08
    • A61B5/14503A61B5/14532A61B2562/222A61N1/05A61N1/08Y10T29/49204
    • A multiple-conductor electrical lead for use with medical device systems and a method of manufacture is disclosed. The multiple-conductor electrical lead comprises a central core and has at least one conductor, typically in the form of a ribbon cable, coiled around it along its length. Typically one or more ribbon cables coiled around a central core each comprise a plurality of separate electrical conductors both coupled together along their lengths in series and electrically insulated from one another with an insulating material. The material of the central core, e.g. polyester, stainless steel, nickel titanium, and the structural configuration, e.g. wrapping pitch of the ribbon cable around the central core and number of ribbon cables, are selected based on desired mechanical characteristics. Such multiple-conductor electrical leads are useful, for example, with analyte sensor systems such as amperometric glucose sensor systems used in the management of diabetes.
    • 公开了与医疗装置系统一起使用的多导体电引线和制造方法。 多导体电引线包括中心芯,并且具有至少一个通常为带状电缆形式的导体,其沿​​着其长度卷绕在其周围。 典型地,一个或多个缠绕在中心芯上的带状电缆每个都包括多个分开的电导体,这两个电导体都沿着它们的长度串联连接在一起并且用绝缘材料彼此电绝缘。 中央核心的材料,例如 聚酯,不锈钢,镍钛和结构构造,例如, 根据所需的机械特性来选择将带状电缆的节距缠绕在中央芯部和带状电缆的数量上。 这种多导体电导线可用于例如分析物传感器系统,例如用于管理糖尿病的安培葡萄糖传感器系统。