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1. 发明申请

WO2013177573A3 FOLDOVER SENSORS AND METHODS FOR MAKING AND USING THEM 审中-公开
标题翻译： FOLDOVER传感器及其制造和使用方法
公开(公告)号：WO2013177573A3
公开(公告)日：2014-07-10
申请号：PCT/US2013042763
申请日：2013-05-24
申请人： MEDTRONIC MINIMED INC , LITTLE MEGAN E , WOLFE KATHERINE T , RAGHAVENDHAR GAUTHAM , LIANG BRADLEY CHI , SHAH RAJIV
发明人： LITTLE MEGAN E , WOLFE KATHERINE T , RAGHAVENDHAR GAUTHAM , LIANG BRADLEY CHI , SHAH RAJIV
IPC分类号： A61B5/1486
CPC分类号： A61B5/14532 , A61B5/14865 , A61B2562/125 , A61B2562/166 , A61B2562/222 , C12Q1/001 , C12Q1/006 , G01N27/3272 , Y10T29/49204
摘要： The application disclosed herein includes implantable blood glucose sensors having three dimensional configurations that allow expansive "360°" sensing (i.e. sensing analyte from multiple directions) in the environments in which such sensors are disposed. Disclsed is an analyte sensor apparatus comprising: a base substrate comprising a planar sheet of a flexible material adapted to transition from a first configuration to a second configuration when the base substrate is folded to form a fixed bend; a working electrode, a counter electrode and a reference electrode disposed upon a first surface of the base substrate; a plurality of contact pads disposed upon the first surface of the base substrate; a plurality of electrical conduits disposed upon the first surface of the base substrate, wherein the plurality of electrical conduits are adapted to transmit electrical signals between electrodes and contact pads separated by the fixed bend; and an analyte sensing layer disposed over the working electrode, wherein the analyte sensing layer detectably alters the electrical current at the working electrode in the presence of an analyte; wherein: the base substrate comprises the fixed bend so as to form a configuration in which: at least one electrode is disposed on a first side of the fixed bend; and at least one electrode is disposed on a second side of the fixed bend.
摘要翻译：本文公开的应用包括具有三维结构的可植入血糖传感器，其允许在布置这些传感器的环境中进行膨胀的“360°”感测（即感测来自多个方向的分析物）。分解物是分析物传感器装置，包括：基底基底，其包括柔性材料的平面片，所述平面片适于在所述基底基底被折叠以形成固定弯曲时从第一构型转变到第二构型; 工作电极，对置电极和设置在所述基底基板的第一表面上的参考电极; 设置在所述基底基板的第一表面上的多个接触焊盘; 多个电导管，其设置在所述基底基板的所述第一表面上，其中所述多个电导管适于在电极与由所述固定弯曲部分开的接触垫之间传输电信号; 以及分析物感测层，其设置在所述工作电极之上，其中所述分析物感测层在分析物的存在下可检测地改变所述工作电极处的电流; 其中：所述基底基板包括所述固定弯曲部，以便形成其中：至少一个电极设置在所述固定弯曲部的第一侧上; 并且至少一个电极设置在固定弯管的第二侧上。

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