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1. 发明申请

WO2011084230A1 AIR TOLERANT IMPLANTABLE PISTON PUMP 审中-公开
标题翻译：耐候可活塞泵
公开(公告)号：WO2011084230A1
公开(公告)日：2011-07-14
申请号：PCT/US2010/055781
申请日：2010-11-08
申请人： MEDTRONIC, INC. , HAASE, James, M. , WHITEHEAD, Nicholas, R. , MEZERA, Ronald, L.
发明人： HAASE, James, M. , WHITEHEAD, Nicholas, R. , MEZERA, Ronald, L.
IPC分类号： A61M5/142 , F04B53/00 , A61M5/165
CPC分类号： A61M5/14276 , A61M5/14216 , A61M5/165 , A61M5/36 , A61M2205/7518 , F04B17/042 , F04B19/006 , F04B35/045 , F04B53/008 , F04B53/1032
摘要： An implantable infusion device includes a reservoir (13) for housing an infusion medium and a drive mechanism having an inlet chamber (320), a piston (44) and a piston channel (35). The inlet chamber is in fluid communication with the reservoir. The piston channel is in fluid communication with the inlet chamber, and has a distal end and a proximal end, the proximal end being closer to the inlet channel than the distal end. The piston is axially moveable within the piston channel to drive infusion medium out of the distal end of the piston channel. The clearance (410) between the piston and the channel is sufficiently small to prevent undissolved gas in the inlet chamber from passing through the clearance. The inlet chamber may be sufficiently large to allow undissolved gas to accumulate without adversely affecting the performance of the infusion device.
摘要翻译：植入式输注装置包括用于容纳输注介质的储存器（13）和具有入口室（320），活塞（44）和活塞通道（35）的驱动机构。入口室与储存器流体连通。活塞通道与入口室流体连通，并且具有远端和近端，近端比远端更靠近入口通道。活塞在活塞通道内可轴向运动，以将输注介质驱出活塞通道的远端。活塞和通道之间的间隙（410）足够小以防止入口室中的未溶解气体通过间隙。入口室可以足够大以允许未溶解的气体积聚而不会不利地影响输注装置的性能。

2. 发明申请

WO2012060926A1 IMPLANTABLE MEDICAL PUMP DIAGNOSTICS 审中-公开
标题翻译：可植入医用泵诊断
公开(公告)号：WO2012060926A1
公开(公告)日：2012-05-10
申请号：PCT/US2011/049878
申请日：2011-08-31
申请人： MEDTRONIC, INC. , ROGERS, Charles, Randall , ALI, Irfan, Z. , MEZERA, Ronald, L. , MIESEL, Keith, A. , SARKINEN, Scott, A. , WHITEHEAD, Nicholas, R.
发明人： ROGERS, Charles, Randall , ALI, Irfan, Z. , MEZERA, Ronald, L. , MIESEL, Keith, A. , SARKINEN, Scott, A. , WHITEHEAD, Nicholas, R.
IPC分类号： A61M5/142
CPC分类号： A61M5/16809 , A61M5/14216 , A61M5/14276 , A61M2005/16863 , A61M2005/16868 , A61M2005/16872
摘要： A method of detecting a fault condition within an implantable medical pump comprises delivering therapeutic fluid using a medical pump comprising an actuation mechanism configured to be energized to provide a pump stroke, detecting a property associated with energizing the actuation mechanism, and determining whether the property associated with energizing the actuation mechanism indicates that a fault condition exists with the medical pump.
摘要翻译：检测可植入医疗泵内的故障状况的方法包括使用包括致动机构的医疗泵输送治疗流体，所述致动机构被配置为通电以提供泵行程，检测与致动机构通电相关联的属性，以及确定属性是否相关联通过致动机构通电，指示医疗泵存在故障状况。

3. 发明申请

WO2008134092A1 RESIDUAL ENERGY RECOVERY IN A DRUG DELIVERY DEVICE 审中-公开
标题翻译：药物递送装置中的残留能量恢复
公开(公告)号：WO2008134092A1
公开(公告)日：2008-11-06
申请号：PCT/US2008/050589
申请日：2008-01-09
申请人： MEDTRONIC, INC. , SARKINEN, Scott, A. , PECLAT, Christian , HAASE, James, M. , MEZERA, Ronald, L.
发明人： SARKINEN, Scott, A. , PECLAT, Christian , HAASE, James, M. , MEZERA, Ronald, L.
IPC分类号： A61M5/142 , H02J7/00 , H02M3/156
CPC分类号： A61M5/14276 , A61M2205/8212 , H02J7/32 , H02J7/345
摘要： An implantable drug delivery device includes a pump motor that is driven by electrical energy from a storage capacitor. At the end of each pump delivery cycle, electrical energy stored in the pump motor is recovered and returned to the storage capacitor, so that it can be used in subsequent delivery cycles.
摘要翻译：可植入药物递送装置包括由来自存储电容器的电能驱动的泵电动机。在每个泵输送周期结束时，存储在泵电机中的电能被恢复并返回到存储电容器，使得其可以在随后的递送周期中使用。

4. 发明申请

WO2008134107A1 IMPLANTABLE DRUG DELIVERY DEVICE WITH PROGRAMMABLE RATE CAPACITOR CHARGE CONTROL 审中-公开
标题翻译：具有可编程速率电容充电控制的可植入式药物递送装置
公开(公告)号：WO2008134107A1
公开(公告)日：2008-11-06
申请号：PCT/US2008/054064
申请日：2008-02-15
申请人： MEDTRONIC, INC. , SARKINEN, Scott, A. , PECLAT, Christian , HAASE, James, M. , MEZERA, Ronald, L.
发明人： SARKINEN, Scott, A. , PECLAT, Christian , HAASE, James, M. , MEZERA, Ronald, L.
IPC分类号： A61M5/142 , H02M3/156
CPC分类号： A61M5/14276 , A61M2205/3523 , A61M2205/3561 , A61M2205/8212 , H02J7/345
摘要： An implantable drug delivery device includes a pump motor that is asserted by drive currents from a storage capacitor. A programmable rate charge control delivers charging current from a battery to the storage capacitor based upon a programmable charge rate value, a minimum battery voltage value, sensed charging current, and sensed battery voltage. When sensed battery voltage droops to below a threshold value, the charge control reduces the charging rate value until other electrical loads within the drug device have been serviced and battery voltage is restored. The charge control also monitors capacitor voltage and provides a charge complete signal to a motor control, which then connects the pump motor to the storage capacitor to produce a pump stroke. Efficiency of charging is enhanced by controlling the charging at a programmable substantially constant rate.
摘要翻译：可植入药物递送装置包括通过来自存储电容器的驱动电流断言的泵电动机。可编程速率充电控制器基于可编程充电速率值，最小电池电压值，检测到的充电电流和检测到的电池电压，将充电电流从电池传送到存储电容器。当感测到的电池电压下降到阈值以下时，充电控制降低充电速率值，直到药物装置内的其它电气负载得到维护并且电池电压恢复。充电控制还监控电容器电压，并向电机控制器提供充电完成信号，然后将电机控制器连接到储能电容器以产生泵冲程。通过以可编程的基本上恒定的速率控制充电来增强充电效率。

5. 发明申请

WO2008147605A1 END OF STROKE DETECTION FOR ELECTROMAGNETIC PUMP 审中-公开
标题翻译：电磁泵检测结束
公开(公告)号：WO2008147605A1
公开(公告)日：2008-12-04
申请号：PCT/US2008/061142
申请日：2008-04-22
申请人： MEDTRONIC, INC. , SARKINEN, Scott A. , PECLAT, Christian , HAASE, James, M. , MEZERA, Ronald, L.
发明人： SARKINEN, Scott A. , PECLAT, Christian , HAASE, James, M. , MEZERA, Ronald, L.
IPC分类号： F04B17/04 , F04B49/06 , A61M5/142
CPC分类号： F04B17/048 , A61M5/14216 , A61M5/14276 , A61M2205/8212 , F04B49/06 , F04B2201/0201 , F04B2203/0401 , F04B2203/0402 , F04B2203/0403
摘要： An electromagnetic pump comprising a voltage sense device (124) for sensing the electrical voltage applied to the coil, a current sense device (122) for sensing the coil current, and control electronics (120) to detect the end of a pump stroke based on a change in flux over time calculated as a function of sensed coil current and sensed electrical voltage. Implantable infusion device comprising the said electromagnetic pump.
摘要翻译：一种电磁泵，包括用于感测施加到线圈的电压的电压感测装置（124），用于感测线圈电流的电流感测装置（122），以及控制电子装置（120），以基于根据感测到的线圈电流和检测到的电压，随时间变化的通量变化。包括所述电磁泵的植入式输注装置。

6. 发明申请

WO1997040791A1 IMPLANTABLE EYELID ELECTRODE AND METHOD OF IMPLANTING SAME 审中-公开
标题翻译：可植入的眼睛电极及其相关的方法
公开(公告)号：WO1997040791A1
公开(公告)日：1997-11-06
申请号：PCT/US1997005092
申请日：1997-03-25
申请人： MEDTRONIC, INC.
发明人： MEDTRONIC, INC. , TESTERMAN, Roy, L. , ERICKSON, Donald, J. , MEZERA, Ronald, L. , NEISZ, Johann, J.
IPC分类号： A61F09/007
CPC分类号： A61N1/36046 , A61F9/00718 , A61N1/05
摘要： The implantable eyelid electrode apparatus includes a body of nonconductive material having first and second edges and first and second ends. A longitudinal axis extends between the first and second ends and a distance from the longitudinal axis to at least one of the first and second edges decreases towards at least one of the first and second ends. Conductive material is positioned at a surface of the body and at least one lead wire is in electrical contact with the conductive material. Further, the conductive material may include a number of conductive electrodes which are capable of being connected as an anode, a cathode, or left in an open configuration. The conductive electrodes may be strip electrodes positioned perpendicular to the longitudinal axis, and further, the plurality of conductive electrodes may be configured in a guarded multipolar configuration. An electrode device may be implanted in the upper eyelid or the lower eyelid or both. Moreover, a method for implanting an electrode apparatus includes positioning the electrode apparatus adjacent the orbicularis oculi muscle fiber such that the conductive material of the implantable eyelid electrode is adjacent the surface of the muscle fibers. The conductive electrodes, which may be of a strip configuration, are positioned with their length perpendicular to the muscle fibers, when implanted, to promote current passing parallel to the muscle fibers.
摘要翻译：可植入式眼睑电极装置包括具有第一和第二边缘以及第一和第二端的非导电材料体。纵向轴线在第一和第二端部之间延伸，并且从纵向轴线到第一和第二边缘中的至少一个的距离朝着第一和第二端部中的至少一个减小。导电材料位于主体的表面，并且至少一根引线与导电材料电接触。此外，导电材料可以包括能够作为阳极连接的多个导电电极，阴极，或者处于打开构型的左侧。导电电极可以是垂直于纵向轴线定位的带状电极，此外，多个导电电极可以被配置成保护的多极配置。电极装置可以植入上眼睑或下眼睑或两者。此外，用于植入电极装置的方法包括将电极装置定位在眼轮匝肌纤维附近，使得可植入眼睑电极的导电材料邻近肌肉纤维的表面。当植入时，可以具有带状构造的导电电极的长度与肌肉纤维垂直，以促进平行于肌肉纤维的电流通过。

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