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1. 发明申请

WO2015199765A1 METHOD OF ZIRCONIUM PHOSPHATE RECHARGING 审中-公开
标题翻译：磷酸锌补充方法
公开(公告)号：WO2015199765A1
公开(公告)日：2015-12-30
申请号：PCT/US2015/019901
申请日：2015-03-11
申请人： MEDTRONIC, INC. , PUDIL, Bryant, J. , LYU, Suping , GROVENDER, Eric , HOBOT, Christopher, M. , GERBER, Martin, T.
发明人： PUDIL, Bryant, J. , LYU, Suping , GROVENDER, Eric , HOBOT, Christopher, M. , GERBER, Martin, T.
IPC分类号： A61M1/14
CPC分类号： A61M1/1696 , B01J39/09 , C01B25/45
摘要： Methods and related apparatuses for sorbent recharging are provided. The methods and related apparatuses for recharging can recharge a specific rechargeable layer of a sorbent material such as zirconium phosphate in a sorbent cartridge. The methods and apparatuses include passing solutions containing combinations of acids, bases and salts through a module containing a rechargeable sorbent material such as zirconium phosphate in order to replace ions bound to the zirconium phosphate with hydrogen and sodium ions. The method allows for a customizable zirconium phosphate, with control over the ratios of sodium to hydrogen on the recharged zirconium phosphate.
摘要翻译：提供吸附剂再充电的方法和相关设备。用于再充电的方法和相关装置可以对吸附剂盒中的吸附剂材料例如磷酸锆的特定可再充电层进行再充电。所述方法和装置包括通过含有可再充电的吸附剂材料如磷酸锆的模块来传递含有酸，碱和盐的组合的溶液，以便用氢和钠离子代替与磷酸锆结合的离子。该方法允许可定制的磷酸锆，控制再充电的磷酸锆上钠与氢的比例。

2. 发明申请

WO2012148789A1 CHRONIC PH OR ELECTROLYTE MONITORING 审中-公开
标题翻译：慢性PH或电解质监测
公开(公告)号：WO2012148789A1
公开(公告)日：2012-11-01
申请号：PCT/US2012/034333
申请日：2012-04-19
申请人： MEDTRONIC, INC. , GERBER, Martin T. , LYU, Suping , PUDIL, Bryant J.
发明人： GERBER, Martin T. , LYU, Suping , PUDIL, Bryant J.
IPC分类号： A61B5/145 , A61B5/00 , A61M1/14 , A61M1/16 , A61M1/34
CPC分类号： A61M1/1603 , A61B5/0031 , A61B5/026 , A61B5/0295 , A61B5/053 , A61B5/0537 , A61B5/145 , A61B5/14503 , A61B5/14535 , A61B5/14539 , A61B5/14546 , A61B5/4836 , A61B5/4848 , A61B5/4875 , A61B5/6866 , A61B5/7282 , A61B2560/0223 , A61M1/00 , A61M1/14 , A61M1/16 , A61M1/1601 , A61M1/1605 , A61M1/1607 , A61M1/1613 , A61M1/28 , A61M1/34 , A61M1/3403 , A61M1/342 , A61M1/3607 , A61M1/3609 , A61M1/361 , A61M1/3612 , A61M1/3672 , A61M2202/0498 , A61M2205/04 , A61M2205/18 , A61M2205/33 , A61M2205/3303 , A61M2205/3306 , A61M2205/3313 , A61M2205/3331 , A61M2205/3334 , A61M2205/3375 , A61M2205/3523 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2205/60 , A61M2205/70 , A61M2230/00 , A61M2230/005 , A61M2230/06 , A61M2230/20 , A61M2230/207 , A61M2230/208 , A61M2230/65 , B01D61/00 , B01D61/32 , B01D65/02 , B01D2321/12 , B01D2321/40 , G06F19/00
摘要： Uses include monitoring blood pH or electrolyte levels and setting initial fluid parameters, such as dialysate fluid parameters or replacement fluid parameters, for a blood fluid removal session based the monitored data. Blood fluid removal systems may employ sensors that monitor blood pH or electrolyte levels to adjust the fluid parameters during a blood fluid removal session.
摘要翻译：用途包括监测血液pH值或电解质水平，并根据监测数据设定初始流体参数，如透析液参数或替代液体参数，用于血液流体清除会话。血液清除系统可以使用监测血液pH值或电解质水平的传感器，以在血液清除期间调整流体参数。

3. 发明申请

WO2013101292A2 FLUID VOLUME MONITORING FOR PATIENTS WITH RENAL DISEASE 审中-公开
标题翻译：流感病毒监测用于患有肾病的患者
公开(公告)号：WO2013101292A2
公开(公告)日：2013-07-04
申请号：PCT/US2012/034327
申请日：2012-04-19
申请人： MEDTRONIC, INC. , GERBER, Martin, T. , BURNES, John, E. , LYU, Suping , VENKATESH, Manda, R. , PUDIL, Bryant, J.
发明人： GERBER, Martin, T. , BURNES, John, E. , LYU, Suping , VENKATESH, Manda, R. , PUDIL, Bryant, J.
IPC分类号： A61M1/14
CPC分类号： A61M1/1603 , A61B5/0031 , A61B5/026 , A61B5/0295 , A61B5/053 , A61B5/0537 , A61B5/145 , A61B5/14503 , A61B5/14535 , A61B5/14539 , A61B5/14546 , A61B5/4836 , A61B5/4848 , A61B5/4875 , A61B5/6866 , A61B5/7282 , A61B2560/0223 , A61M1/00 , A61M1/14 , A61M1/16 , A61M1/1601 , A61M1/1605 , A61M1/1607 , A61M1/1613 , A61M1/28 , A61M1/34 , A61M1/3403 , A61M1/342 , A61M1/3607 , A61M1/3609 , A61M1/361 , A61M1/3612 , A61M1/3672 , A61M2202/0498 , A61M2205/04 , A61M2205/18 , A61M2205/33 , A61M2205/3303 , A61M2205/3306 , A61M2205/3313 , A61M2205/3331 , A61M2205/3334 , A61M2205/3375 , A61M2205/3523 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2205/60 , A61M2205/70 , A61M2230/00 , A61M2230/005 , A61M2230/06 , A61M2230/20 , A61M2230/207 , A61M2230/208 , A61M2230/65 , B01D61/00 , B01D61/32 , B01D65/02 , B01D2321/12 , B01D2321/40 , G06F19/00
摘要： A use includes initiating a blood fluid removal session of a patient; monitoring an indicator of tissue fluid volume of the patient, or a portion thereof, during the blood fluid removal session; monitoring an indicator of blood fluid volume of the patient during the blood fluid removal session; determining whether a ratio of the indicator of tissue fluid volume to indicator of blood fluid volume is outside of a predetermined range; and altering the rate of fluid removal during the blood fluid removal session if the ratio is determined to be outside of the predetermined range. A blood fluid removal system may be configured to carry out the use.
摘要翻译：一种用途包括启动患者的血液流体清除会话; 在血液清除会话期间监测患者或其部分的组织液体体积的指标; 在血液清除期间监测患者的血液体积的指标; 确定组织液体体积指标与血液体积指标之间的比率是否超出预定范围; 以及如果所述比例被确定在所述预定范围之外，则改变在所述血液流体清除会话期间的流体去除速率。血液清除系统可以被配置为执行使用。

4. 发明申请

WO2012148787A1 BLOOD FLUID REMOVAL SYSTEM PERFORMANCE MONITORING 审中-公开
标题翻译：血液流体清除系统性能监测
公开(公告)号：WO2012148787A1
公开(公告)日：2012-11-01
申请号：PCT/US2012/034331
申请日：2012-04-19
申请人： MEDTRONIC, INC. , GERBER, Martin T. , LYU, Suping , PUDIL, Bryant J.
发明人： GERBER, Martin T. , LYU, Suping , PUDIL, Bryant J.
IPC分类号： A61M1/14 , B01D61/00 , B01D61/32 , A61M1/34
CPC分类号： A61M1/1603 , A61B5/0031 , A61B5/026 , A61B5/0295 , A61B5/053 , A61B5/0537 , A61B5/145 , A61B5/14503 , A61B5/14535 , A61B5/14539 , A61B5/14546 , A61B5/4836 , A61B5/4848 , A61B5/4875 , A61B5/6866 , A61B5/7282 , A61B2560/0223 , A61M1/00 , A61M1/14 , A61M1/16 , A61M1/1601 , A61M1/1605 , A61M1/1607 , A61M1/1613 , A61M1/28 , A61M1/34 , A61M1/3403 , A61M1/342 , A61M1/3607 , A61M1/3609 , A61M1/361 , A61M1/3612 , A61M1/3672 , A61M2202/0498 , A61M2205/04 , A61M2205/18 , A61M2205/33 , A61M2205/3303 , A61M2205/3306 , A61M2205/3313 , A61M2205/3331 , A61M2205/3334 , A61M2205/3375 , A61M2205/3523 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2205/60 , A61M2205/70 , A61M2230/00 , A61M2230/005 , A61M2230/06 , A61M2230/20 , A61M2230/207 , A61M2230/208 , A61M2230/65 , B01D61/00 , B01D61/32 , B01D65/02 , B01D2321/12 , B01D2321/40 , G06F19/00
摘要： Monitoring of the performance of a blood fluid removal medium of a blood fluid removal device includes monitoring of condition, such as fluid flow rate or concentration of blood waste product, downstream of the medium. Upstream monitoring of the condition may also be performed to enhance the ability to determine whether the blood fluid removal medium is performing within predetermined ranges.
摘要翻译：监测血液流体去除装置的血液流体去除介质的性能包括在介质下游监测诸如流体流动速率或血液废物产物浓度的状况。还可以进行条件的上游监视，以增强确定血液流体去除介质是否在预定范围内执行的能力。

5. 发明申请

WO2012148791A1 INTERSESSION MONITORING FOR BLOOD FLUID REMOVAL THERAPY 审中-公开
标题翻译：用于血液流体去除治疗的间歇监测
公开(公告)号：WO2012148791A1
公开(公告)日：2012-11-01
申请号：PCT/US2012/034335
申请日：2012-04-19
申请人： MEDTRONIC, INC. , GERBER, Martin T. , LYU, Suping , PUDIL, Bryant J.
发明人： GERBER, Martin T. , LYU, Suping , PUDIL, Bryant J.
IPC分类号： A61M1/34 , A61M1/16
CPC分类号： A61M1/1603 , A61B5/0031 , A61B5/026 , A61B5/0295 , A61B5/053 , A61B5/0537 , A61B5/145 , A61B5/14503 , A61B5/14535 , A61B5/14539 , A61B5/14546 , A61B5/4836 , A61B5/4848 , A61B5/4875 , A61B5/6866 , A61B5/7282 , A61B2560/0223 , A61M1/00 , A61M1/14 , A61M1/16 , A61M1/1601 , A61M1/1605 , A61M1/1607 , A61M1/1613 , A61M1/28 , A61M1/34 , A61M1/3403 , A61M1/342 , A61M1/3607 , A61M1/3609 , A61M1/361 , A61M1/3612 , A61M1/3672 , A61M2202/0498 , A61M2205/04 , A61M2205/18 , A61M2205/33 , A61M2205/3303 , A61M2205/3306 , A61M2205/3313 , A61M2205/3331 , A61M2205/3334 , A61M2205/3375 , A61M2205/3523 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2205/60 , A61M2205/70 , A61M2230/00 , A61M2230/005 , A61M2230/06 , A61M2230/20 , A61M2230/207 , A61M2230/208 , A61M2230/65 , B01D61/00 , B01D61/32 , B01D65/02 , B01D2321/12 , B01D2321/40 , G06F19/00
摘要： Uses for monitoring patient parameters and blood fluid removal system parameters include identifying those system parameters that result in improved patient parameters or in worsened patent parameters. By comparing the patient's current parameters to past parameters in response to system parameters or changes in system parameters, a blood fluid removal system may be able to avoid future use of parameters that may harm the patient and may be able to learn which parameters are likely to be most effective in treating the patient in a blood fluid removal session.
摘要翻译：用于监测患者参数和血液流体清除系统参数的用途包括识别导致改善患者参数或恶化的专利参数的系统参数。通过根据系统参数或系统参数的变化将患者的当前参数与过去的参数进行比较，血液流体清除系统可能能够避免将来使用可能损害患者的参数，并且可能能够了解哪些参数可能在血液清除术中治疗患者最有效。

6. 发明申请

WO2012148790A1 ADAPTIVE SYSTEM FOR BLOOD FLUID REMOVAL 审中-公开
标题翻译：血液清除自适应系统
公开(公告)号：WO2012148790A1
公开(公告)日：2012-11-01
申请号：PCT/US2012/034334
申请日：2012-04-19
申请人： MEDTRONIC, INC. , GERBER, Martin T. , BURNES, John E. , LYU, Suping , VENKATESH, Manda R. , PUDIL, Bryant J.
发明人： GERBER, Martin T. , BURNES, John E. , LYU, Suping , VENKATESH, Manda R. , PUDIL, Bryant J.
IPC分类号： A61M1/16 , B01D61/00
CPC分类号： A61M1/1603 , A61B5/0031 , A61B5/026 , A61B5/0295 , A61B5/053 , A61B5/0537 , A61B5/145 , A61B5/14503 , A61B5/14535 , A61B5/14539 , A61B5/14546 , A61B5/4836 , A61B5/4848 , A61B5/4875 , A61B5/6866 , A61B5/7282 , A61B2560/0223 , A61M1/00 , A61M1/14 , A61M1/16 , A61M1/1601 , A61M1/1605 , A61M1/1607 , A61M1/1613 , A61M1/28 , A61M1/34 , A61M1/3403 , A61M1/342 , A61M1/3607 , A61M1/3609 , A61M1/361 , A61M1/3612 , A61M1/3672 , A61M2202/0498 , A61M2205/04 , A61M2205/18 , A61M2205/33 , A61M2205/3303 , A61M2205/3306 , A61M2205/3313 , A61M2205/3331 , A61M2205/3334 , A61M2205/3375 , A61M2205/3523 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2205/60 , A61M2205/70 , A61M2230/00 , A61M2230/005 , A61M2230/06 , A61M2230/20 , A61M2230/207 , A61M2230/208 , A61M2230/65 , B01D61/00 , B01D61/32 , B01D65/02 , B01D2321/12 , B01D2321/40 , G06F19/00
摘要： Uses for monitoring patient parameters and blood fluid removal system parameters include identifying those system parameters that result in improved patient parameters or in worsened patient parameters. By comparing the patient's past responses to system parameters or changes in system parameters, a blood fluid removal system may be able to avoid future use of parameters that may harm the patient and may be able to learn which parameters are likely to be most effective in treating the patient in a blood fluid removal session.
摘要翻译：用于监测患者参数和血液流体清除系统参数的用途包括识别导致患者参数改善或患者参数恶化的系统参数。通过将患者的过去反应与系统参数或系统参数的变化进行比较，血液流体清除系统可能能够避免将来使用可能损害患者的参数，并且可能能够了解哪些参数在治疗中可能最有效患者在血液清除会话中。

7. 发明申请

WO2012148788A1 CARDIOVASCULAR MONITORING FOR FLUID REMOVAL PROCESSES 审中-公开
标题翻译：用于流体移除过程的心血管监测
公开(公告)号：WO2012148788A1
公开(公告)日：2012-11-01
申请号：PCT/US2012/034332
申请日：2012-04-19
申请人： MEDTRONIC, INC. , GERBER, Martin T. , BURNES, John E. , LYU, Suping , VENKATESH, Manda R. , PUDIL, Bryant J.
发明人： GERBER, Martin T. , BURNES, John E. , LYU, Suping , VENKATESH, Manda R. , PUDIL, Bryant J.
IPC分类号： A61M1/14 , B01D61/00
CPC分类号： A61M1/1603 , A61B5/0031 , A61B5/026 , A61B5/0295 , A61B5/053 , A61B5/0537 , A61B5/145 , A61B5/14503 , A61B5/14535 , A61B5/14539 , A61B5/14546 , A61B5/4836 , A61B5/4848 , A61B5/4875 , A61B5/6866 , A61B5/7282 , A61B2560/0223 , A61M1/00 , A61M1/14 , A61M1/16 , A61M1/1601 , A61M1/1605 , A61M1/1607 , A61M1/1613 , A61M1/28 , A61M1/34 , A61M1/3403 , A61M1/342 , A61M1/3607 , A61M1/3609 , A61M1/361 , A61M1/3612 , A61M1/3672 , A61M2202/0498 , A61M2205/04 , A61M2205/18 , A61M2205/33 , A61M2205/3303 , A61M2205/3306 , A61M2205/3313 , A61M2205/3331 , A61M2205/3334 , A61M2205/3375 , A61M2205/3523 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2205/60 , A61M2205/70 , A61M2230/00 , A61M2230/005 , A61M2230/06 , A61M2230/20 , A61M2230/207 , A61M2230/208 , A61M2230/65 , B01D61/00 , B01D61/32 , B01D65/02 , B01D2321/12 , B01D2321/40 , G06F19/00
摘要： A use includes initiating a blood fluid removal session for a patient in need thereof; monitoring a cardiovascular parameter of the patient; determining whether the indicator of the cardiovascular state crosses a predetermined threshold; and altering a parameter of the blood fluid removal session if the indicator is determined have crossed the threshold.
摘要翻译：一种用途包括启动有需要的患者的血液流体清除会话; 监测患者的心血管参数; 确定心血管状态的指标是否超过预定阈值; 如果所述指示符已经超过所述阈值，则改变所述血液流体去除会话的参数。

8. 发明申请

WO2012148786A1 ELECTROLYTE AND pH MONITORING FOR FLUID REMOVAL PROCESSES 审中-公开
标题翻译：电解质和pH监测流体去除方法
公开(公告)号：WO2012148786A1
公开(公告)日：2012-11-01
申请号：PCT/US2012/034330
申请日：2012-04-19
申请人： MEDTRONIC, INC. , GERBER, Martin T. , BURNES, John E. , LYU, Suping , VENKATESH, Manda R. , PUDIL, Bryant J.
发明人： GERBER, Martin T. , BURNES, John E. , LYU, Suping , VENKATESH, Manda R. , PUDIL, Bryant J.
IPC分类号： A61B5/145 , A61M1/16 , A61M1/34 , A61M1/14
CPC分类号： A61M1/1603 , A61B5/0031 , A61B5/026 , A61B5/0295 , A61B5/053 , A61B5/0537 , A61B5/145 , A61B5/14503 , A61B5/14535 , A61B5/14539 , A61B5/14546 , A61B5/4836 , A61B5/4848 , A61B5/4875 , A61B5/6866 , A61B5/7282 , A61B2560/0223 , A61M1/00 , A61M1/14 , A61M1/16 , A61M1/1601 , A61M1/1605 , A61M1/1607 , A61M1/1613 , A61M1/28 , A61M1/34 , A61M1/3403 , A61M1/342 , A61M1/3607 , A61M1/3609 , A61M1/361 , A61M1/3612 , A61M1/3672 , A61M2202/0498 , A61M2205/04 , A61M2205/18 , A61M2205/33 , A61M2205/3303 , A61M2205/3306 , A61M2205/3313 , A61M2205/3331 , A61M2205/3334 , A61M2205/3375 , A61M2205/3523 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2205/60 , A61M2205/70 , A61M2230/00 , A61M2230/005 , A61M2230/06 , A61M2230/20 , A61M2230/207 , A61M2230/208 , A61M2230/65 , B01D61/00 , B01D61/32 , B01D65/02 , B01D2321/12 , B01D2321/40 , G06F19/00
摘要： Uses include monitoring indicators of blood pH or blood electrolyte levels during a blood fluid removal session and adjusting concentrations of pH buffers or electrolytes in dialysate or replacement fluid used during the session based on the monitored indicators. Blood fluid removal systems may employ sensors that monitor blood pH or electrolyte levels to adjust the fluid parameters during a blood fluid removal session.
摘要翻译：用途包括在血液清除过程中血液pH值或血液电解质水平的监测指标，并根据监测的指标调整在会话期间使用的透析液或替代液中的pH缓冲液或电解质的浓度。血液清除系统可以使用监测血液pH值或电解质水平的传感器，以在血液清除期间调整流体参数。

9. 发明申请

WO2012148785A2 MONITORING FLUID VOLUME FOR PATIENTS WITH RENAL DISEASE 审中-公开
标题翻译：监测患有肾病的患者的流体量
公开(公告)号：WO2012148785A2
公开(公告)日：2012-11-01
申请号：PCT/US2012/034329
申请日：2012-04-19
申请人： MEDTRONIC, INC. , GERBER, Martin T. , BURNES, John E. , LYU, Suping , VENKATESH, Manda R. , PUDIL, Bryant J.
发明人： GERBER, Martin T. , BURNES, John E. , LYU, Suping , VENKATESH, Manda R. , PUDIL, Bryant J.
IPC分类号： A61M1/14 , B01D61/00 , A61B5/053 , A61M1/00 , A61B5/0295
CPC分类号： A61M1/1603 , A61B5/0031 , A61B5/026 , A61B5/0295 , A61B5/053 , A61B5/0537 , A61B5/145 , A61B5/14503 , A61B5/14535 , A61B5/14539 , A61B5/14546 , A61B5/4836 , A61B5/4848 , A61B5/4875 , A61B5/6866 , A61B5/7282 , A61B2560/0223 , A61M1/00 , A61M1/14 , A61M1/16 , A61M1/1601 , A61M1/1605 , A61M1/1607 , A61M1/1613 , A61M1/28 , A61M1/34 , A61M1/3403 , A61M1/342 , A61M1/3607 , A61M1/3609 , A61M1/361 , A61M1/3612 , A61M1/3672 , A61M2202/0498 , A61M2205/04 , A61M2205/18 , A61M2205/33 , A61M2205/3303 , A61M2205/3306 , A61M2205/3313 , A61M2205/3331 , A61M2205/3334 , A61M2205/3375 , A61M2205/3523 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2205/60 , A61M2205/70 , A61M2230/00 , A61M2230/005 , A61M2230/06 , A61M2230/20 , A61M2230/207 , A61M2230/208 , A61M2230/65 , B01D61/00 , B01D61/32 , B01D65/02 , B01D2321/12 , B01D2321/40 , G06F19/00
摘要： A use includes monitoring an indicator of fluid volume of a patient via a sensor device, and setting an initial fluid volume removal prescription for a blood fluid removal session based on the monitored indicator of fluid volume. The use may further include transmitting data regarding the indicator of fluid volume from the implantable sensor device to fluid removal device. In some embodiments, the fluid removal device sets or calculated the initial fluid volume removal prescription based on the data received from the implantable sensor. The indicator of fluid volume may be an indicator of tissue fluid volume or an indicator of blood fluid volume.
摘要翻译：一种用途包括通过传感器装置监测患者体液量的指示，以及基于所监测的流体体积的指示器设定用于血液流体清除会话的初始流体体积去除处方。该用途还可以包括将关于流体体积指示器的数据从可植入传感器装置传送到流体移除装置。在一些实施例中，流体移除装置基于从可植入传感器接收的数据设置或计算初始流体体积去除处方。流体体积的指标可以是组织液体体积的指标或血液体积的指标。

10. 发明申请

WO2013019994A2 HEMODIALYSIS SYSTEM HAVING A FLOW PATH WITH A CONTROLLED COMPLIANT VOLUME 审中-公开
标题翻译：血液透析系统具有可控制的体积流量路径
公开(公告)号：WO2013019994A2
公开(公告)日：2013-02-07
申请号：PCT/US2012/049398
申请日：2012-08-02
申请人： MEDTRONIC, INC. , KELLY, Thomas, D. , LYU, Suping , PUDIL, Bryant, J. , MEYER, Thomas, E.
发明人： KELLY, Thomas, D. , LYU, Suping , PUDIL, Bryant, J. , MEYER, Thomas, E.
IPC分类号： A61M1/34 , A61M1/16 , A61M1/38
CPC分类号： A61M1/3482 , A61M1/1696 , A61M2202/0021 , A61M2202/0413
摘要： Systems and methods for the performance of kidney replacement therapy having or using a dialyzer, control components, sorbent cartridge and fluid reservoirs configured to be of a weight and size suitable to be worn or carried by an individual requiring treatment are disclosed. The system for performing kidney replacement therapy has a controlled compliance dialysis circuit, where a control pump controls the bi-directional movement of fluid across a dialysis membrane. The dialysis circuit and an extracorporeal circuit for circulating blood are in fluid communication through the dialysis membrane. The flux of fluid moving between the extracorporeal circuit and the dialysis circuit is modified by the rate at which the control pump is operating such that a rate of ultrafiltration and convective clearance can be controlled. The system provides for the monitoring of an inlet and outlet conductivity of the sorbent cartridge to provide a facility to quantify or monitor the removal of urea by the sorbent cartridge.
摘要翻译：用于进行具有或使用透析器，对照组分，吸附剂盒和流体储器的肾替代治疗的系统和方法，所述透析器，对照组分，吸附剂盒和流体储器被配置为适合由个体穿戴或携带的重量和尺寸治疗被披露。用于进行肾脏替代疗法的系统具有受控的依从性透析回路，其中控制泵控制流体穿过透析膜的双向运动。透析回路和用于循环血液的体外回路通过透析膜流体连通。在体外回路和透析回路之间移动的流体流量通过控制泵运行的速率而改变，使得可以控制超滤和对流间隙的速率。该系统提供了对吸附剂盒的入口和出口电导率的监测，以提供量化或监测吸附剂盒去除尿素的设施。

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