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    • 7. 发明申请
    • EVALUATING VENTRICULAR SYNCHRONY BASED ON PHASE ANGLE BETWEEN SENSOR SIGNALS
    • 基于传感器信号之间的相位角评估气道同步
    • WO2005018740A1
    • 2005-03-03
    • PCT/US2004/025762
    • 2004-08-10
    • MEDTRONIC, INC.CHINCHOY, EdwardDENO, Curtis, D.CHO, Yong, K.
    • CHINCHOY, EdwardDENO, Curtis, D.CHO, Yong, K.
    • A61N1/365
    • A61N1/368A61N1/3627
    • An implantable medical device evaluates ventricular synchrony by determining a phase angle between at least two sensor signals that reflect mechanical contraction of the ventricles. In exemplary embodiments, two intracardiac impedance signals associated with the right and left ventricles, respectively, with two points within either of the left and right ventricles, or with both the left and right ventricles relative to a reference point, are processed. In such embodiments, fundamental frequency phases of each of the impedance signals may be compared to determine the phase angle between the signals. In some embodiments, the signals are used to dynamically adjust one or more timing intervals, such as a V-V timing interval, for delivery of cardiac resynchronization therapy (CRT) pacing. In such embodiments, the one or more timing intervals are periodically adjusted to reduce or possibly eliminate ventricular dysynchrony as indicated by the phase angle between the sensor signals.
    • 可植入医疗装置通过确定反映心室的机械收缩的至少两个传感器信号之间的相位角来评估心室同步。 在示例性实施例中,处理与左心室和左心室相关联的两个心内阻抗信号,其中左心室和右心室内的两个点,或者与左心室和右心室相对于参考点两者。 在这样的实施例中,可以比较每个阻抗信号的基频相位以确定信号之间的相位角。 在一些实施例中,信号用于动态调整一个或多个定时间隔,例如V-V定时间隔,用于递送心脏再同步治疗(CRT)起搏。 在这样的实施例中,周期性地调整一个或多个定时间隔以减少或可能消除如传感器信号之间的相位角所指示的心室异常。
    • 8. 发明申请
    • COORDINATION OF VENTRICULAR PACING IN A LEADLESS PACING SYSTEM
    • 无铅PACING系统中的静态PAC协调
    • WO2016094175A1
    • 2016-06-16
    • PCT/US2015/063650
    • 2015-12-03
    • MEDTRONIC, INC.
    • SAMBELASHVILI, Aleksandre, T.CHO, Yong, K.SHELDON, Todd, J.
    • A61N1/375A61N1/368A61N1/365
    • A61N1/3682A61N1/36578A61N1/368A61N1/3756
    • An implantable medical system is configured to coordinate ventricular pacing with intrinsic depolarizations of another chamber. The implantable medical system includes a leadless pacing device implanted on or within the ventricle. Another implantable medical device is configured to sense an intrinsic depolarization the other chamber of the heart of the patient, and in response to the intrinsic depolarization of the other chamber, deliver an electrical pulse. The leadless pacing device is configured to detect the electrical pulse delivered by the other implantable medical device and, in response to detecting the electrical pulse delivered by the other implantable medical device, deliver a pacing pulse to the ventricle via at least a first electrode in coordination with the intrinsic depolarization of the other chamber.
    • 可植入医疗系统配置为协调心室起搏与另一个室的内在去极化。 可植入医疗系统包括植入在心室上或心室内的无​​引线起搏装置。 另一种可植入医疗装置被配置为感测患者心脏的另一个腔室的固有去极化,并且响应于另一腔室的固有去极化,传送电脉冲。 无引脚起搏装置被配置为检测由另一可植入医疗装置输送的电脉冲,并且响应于检测由另一可植入医疗装置输送的电脉冲,通过至少第一电极协调地将起搏脉冲输送到心室 与另一个房间的内在去极化。