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1. 发明申请

WO2004030747A2 CARDIAC VEIN LEAD WITH FLEXIBLE ANODE AND METHOD FOR FORMING SAME 审中-公开
标题翻译：具有柔性阳极的CARDIAC VEIN引线及其形成方法
公开(公告)号：WO2004030747A2
公开(公告)日：2004-04-15
申请号：PCT/US2003/030354
申请日：2003-09-25
申请人： MEDTRONIC, INC.
发明人： HINE, Douglas, S. , SOMMER, John, L. , BASS, Wayne, R. , MORRIS, Mary, M. , MCINTYRE, Peter, B. , PFEIFFER, Carla, C. , LAFOND, Roger , PETERSON, Patricia, K.
IPC分类号： A61N
CPC分类号： A61N1/056 , A61N2001/0585
摘要： A bipolar cardiac vein lead and method of assembly is provided wherein the lead includes a flexible coil anode electrode such that the lead may be advanced through a tortuous pathway. The coil electrode is coupled to a conductor using a method of assembly that minimizes or eliminates rigid components, maintaining flexibility of the distal lead end. Multi-polar cardiac vein leads may include multiple flexible coil electrodes to achieve pacing and/or sensing in the left atrium and the left ventricle or at multiple left heart sites.
摘要翻译：提供了一种双极心静脉引线和组装方法，其中引线包括柔性线圈阳极电极，使得引线可以通过曲折的通路前进。线圈电极使用最小化或消除刚性部件的组装方法联接到导体，保持远端引线端的柔性。多极心静脉引线可以包括多个柔性线圈电极，以实现左心房和左心室或多个左心脏部位的起搏和/或感测。

2. 发明申请

WO2004028618A1 DEPLOYABLE MEDICAL LEAD FIXATION SYSTEM AND METHOD 审中-公开
标题翻译：可配置医疗铅固定系统和方法
公开(公告)号：WO2004028618A1
公开(公告)日：2004-04-08
申请号：PCT/US2003/029578
申请日：2003-09-22
申请人： MEDTRONIC, INC.
发明人： BJORKLUND, Vicki, L. , SOMMER, John, L. , HINE, Douglas, S. , LOVE, Charles, J. , HESS, Douglas, N. , LOKHOFF, Nicolaas, M.
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/058
摘要： An improved medical lead assembly and method of use is provided. The lead assembly includes a lead body, and a spring member positioned adjacent to the lead body. The spring member may be deployed a selectable amount to maintain the lead body in a fixed location within a patient's body. The spring member may be an expandable coil, a mesh structure that is similar to a stent, or any other similar device that may be positioned in a low-profile state during a lead implant procedure. After the lead is positioned at a target destination, the spring member may be deployed an amount that is selected based on the characteristics of the surrounding tissue, including vessel size. According to one aspect of the invention, the lead assembly may provide means for facilitating chronic lead extraction.
摘要翻译：提供了一种改进的医疗引线组件和使用方法。引线组件包括引线体和邻近引线体定位的弹簧部件。弹簧构件可以部署可选择的量以将引线体保持在患者体内的固定位置。弹簧构件可以是可扩张线圈，类似于支架的网状结构或者在引线植入过程期间可以被定位在低轮廓状态的任何其它类似的装置。在引线定位在目标目的地之后，弹簧构件可以展开一定量，该量基于包括容器尺寸的周围组织的特性来选择。根据本发明的一个方面，引线组件可以提供用于促进慢性铅提取的装置。

3. 发明申请

WO2009121047A1 IMPLANTABLE MEDICAL ELECTRICAL LEAD BODIES PROVIDING IMPROVED ELECTRODE CONTACT 审中-公开
标题翻译：提供改进的电极接触的医疗电气引线体
公开(公告)号：WO2009121047A1
公开(公告)日：2009-10-01
申请号：PCT/US2009/038720
申请日：2009-03-30
申请人： MEDTRONIC, INC. , CLEMENS, William, J. , WERNER, Nicole, L. , LOCH, Deborah, A. , HINE, Douglas, S. , HESS, Douglas, N. , PFEIFFER, Carla, C. , BAXTER, Walton, W.
发明人： CLEMENS, William, J. , WERNER, Nicole, L. , LOCH, Deborah, A. , HINE, Douglas, S. , PFEIFFER, Carla, C. , BAXTER, Walton, W.
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N2001/0585
摘要： A distal section of an implantable medical electrical lead body includes a pair of pre-formed arcuate segments between which an approximately straight segment extends. The approximately straight segment includes a first portion extending distally from a first of the pair pre-formed arcuate segments, a second portion extending from the first portion, a third portion extending from the second to a second of the pair pre-formed arcuate segments. An electrode is coupled to the second portion of the approximately straight segment, and the adjacent first portion has a stiffness which is less than that of the first of the pair pre-formed arcuate segments and preferably less than the stiffness of the third portion, so that, when the distal section of the lead body is implanted, for example, within a cardiac vein, the lead buckles to bring the electrode into closer contact with surrounding tissue.
摘要翻译：植入式医疗电引线主体的远端部分包括一对预先形成的弧形段，大致直线段延伸在该弧形段之间。大致直的部分包括从第一对预成形弧形段向远端延伸的第一部分，从第一部分延伸的第二部分，从该对预成形弧形段的第二部分延伸到第二部分的第三部分。电极耦合到大致直线段的第二部分，并且相邻的第一部分的刚度小于预先形成的一对弓形段中的第一部分的刚度，并且优选地小于第三部分的刚度，因此当引线体的远侧部分植入心脏静脉内时，引线带扣使电极与周围的组织更接近。

4. 发明申请

WO2006012159A1 MULTIPOLAR MEDICAL ELECTRICAL LEAD 审中-公开
标题翻译：多功能医用电线
公开(公告)号：WO2006012159A1
公开(公告)日：2006-02-02
申请号：PCT/US2005/022131
申请日：2005-06-22
申请人： MEDTRONIC, INC. , HINE, Douglas, S. , BRABEC, Scott, J.
发明人： HINE, Douglas, S. , BRABEC, Scott, J.
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N2001/0585
摘要： A pacing lead includes a first pacing cathode coupled to a first conductor, a second pacing cathode coupled to a second conductor, and a flexible anode coupled to a third conductor. The flexible anode has a length less than approximately 10 millimeters and is spaced apart from and proximal to the first pacing cathode and spaced apart from and distal to the second pacing cathode. The spacing between the anode and the first pacing cathode is approximately equal to the spacing between the anode and the second pacing cathode.
摘要翻译：起搏引线包括耦合到第一导体的第一起搏阴极，耦合到第二导体的第二起搏阴极和耦合到第三导体的柔性阳极。柔性阳极具有小于约10毫米的长度，并且与第一起搏阴极间隔开并靠近第一起搏阴极并与第二起搏阴极间隔开并远离第二起搏阴极。阳极和第一起搏阴极之间的间隔大致等于阳极和第二起搏阴极之间的间隔。

5. 发明申请

WO2005016451A1 IMPLANTABLE MEDICAL LEAD CONNECTOR SLEEVES 审中-公开
标题翻译：可伸缩医用引线连接器
公开(公告)号：WO2005016451A1
公开(公告)日：2005-02-24
申请号：PCT/US2004/019265
申请日：2004-06-16
申请人： MEDTRONIC, INC. , HINE, Douglas, S. , SOMMER, John, L. , HESS, Douglas, N.
发明人： HINE, Douglas, S. , SOMMER, John, L. , HESS, Douglas, N.
IPC分类号： A61N1/375
CPC分类号： A61N1/3752
摘要： A connector sleeve includes a lumen adapted to receive a medical lead connector wherein a retention element engages a retention edge formed at a distal end of a connector element included on the lead connector. The connector sleeve further includes a contact element adapted to electrically engage the lead connector element within the lumen and an external conductive surface electrically coupled to the contact element and adapted for electrical engagement within the connector bore of an implantable medical device.
摘要翻译：连接器套管包括适于接收医疗引线连接器的内腔，其中保持元件接合形成在引线连接器上包括的连接器元件的远端处的保持边缘。连接器套筒还包括适于电连接腔内的引线连接器元件的接触元件和电耦合到接触元件的外部导电表面，并且适于电连接在可植入医疗器械的连接器孔内。

6. 发明申请

WO2006044266A1 LEAD STABILIZER AND EXTENSION WIRE 审中-公开
标题翻译：引导稳定器和延长线
公开(公告)号：WO2006044266A1
公开(公告)日：2006-04-27
申请号：PCT/US2005/036242
申请日：2005-10-12
申请人： MEDTRONIC, INC. , HINE, Douglas, S. , BROSTROM, Thomas, D. , BAUER, Ryan, T.
发明人： HINE, Douglas, S. , BROSTROM, Thomas, D. , BAUER, Ryan, T.
IPC分类号： A61N1/05 , A61M25/09
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0578
摘要： A lead stabilization and extension wire that enables the withdrawal of a guide catheter over an electrical medical lead body without dislodging an electrode or sensor from an implantation site or detaching the fixation mechanism and methods of use and a kit are disclosed. The lead stabilizer and retraction wire comprises a wire sheath and an elongated core wire insertable within a sheath lumen. The sheath is insertable within a lead body lumen and includes a movable lead clamp that can engage with a lead connector element and a friction element frictionally engaging the core wire to maintain the extension wire length. The lead stabilizer and retraction wire is insertable into the lead body lumen enabling retraction of the guide catheter over the lead stabilization and extension wire while force is applied through the lead stabilization and extension wire to maintain the distal electrode at the implantation site.
摘要翻译：公开了一种导线稳定和延伸线，其能够引导导管在电气医疗引线体上抽出，而不会从植入部位移除电极或传感器，或者分离固定机构以及使用方法和试剂盒。引线稳定器和回缩线包括线鞘和可插入鞘管内的细长芯线。护套可插入引线体腔内并且包括可移动引线夹，其可与引线连接器元件接合，摩擦元件与芯线摩擦接合以保持延长线长度。引线稳定器和回缩线可插入引线体腔，能够使引导导管回缩到引线稳定和延伸线上，同时通过引线稳定和延伸线施加力，以将远端电极保持在植入位置。

7. 发明申请

WO2005025009A1 MULTI-POLAR ELECTRICAL MEDICAL LEAD CONNECTOR SYSTEM 审中-公开
标题翻译：多极电气导线连接器系统
公开(公告)号：WO2005025009A1
公开(公告)日：2005-03-17
申请号：PCT/US2004/019280
申请日：2004-06-16
申请人： MEDTRONIC, INC. , HINE, Douglas, S. , SOMMER, John, L. , GURLEY, John
发明人： HINE, Douglas, S. , SOMMER, John, L. , GURLEY, John
IPC分类号： H01R13/52
CPC分类号： H01R13/5224 , H01R31/06
摘要： A lead connector including a connector element array is fitted into a selected adaptor from a plurality of adaptors to electrically couple one or more elements of the connector element array, corresponding to one or more selected electrodes from an array of lead electrodes, to one or more contact zones of the selected adaptor in order to facilitate electrical connection with an implantable medical device.
摘要翻译：将包括连接器元件阵列的引线连接器从多个适配器装配到所选择的适配器中，以将来自引线电极阵列的一个或多个所选电极的连接器元件阵列的一个或多个元件电耦合到一个或多个接触区域，以便于与可植入医疗设备的电连接。

8. 发明申请

WO2005023364A1 MULTI-POLAR ELECTRICAL MEDICAL LEAD CONNECTOR SYSTEM 审中-公开
标题翻译：多极电气导线连接器系统
公开(公告)号：WO2005023364A1
公开(公告)日：2005-03-17
申请号：PCT/US2004/019262
申请日：2004-06-16
申请人： MEDTRONIC, INC. , HINE, Douglas, S. , SOMMER, John, Louis
发明人： HINE, Douglas, S. , SOMMER, John, Louis
IPC分类号： A61N1/375
CPC分类号： H01R31/06 , A61N1/3752 , H01R13/5224 , H01R27/00 , H01R2201/12
摘要： A lead connector is terminated proximally by a connector pin and includes a circumferential array of connector pads, each connector pad coupled to an electrode via an elongated insulated conductor. A lumen of an adaptor is adapted to engage the lead connector and includes an electrical contact zone formed therein and positioned for coupling with a one of the array of connector pads, when the connector is engaged within the lumen, in order to facilitate electrical connection of a selected electrode corresponding to the one of the array of connector pads.
摘要翻译：引线连接器由连接器针靠近端接，并且包括连接器焊盘的圆周阵列，每个连接器焊盘通过细长的绝缘导体耦合到电极。适配器的内腔适于接合引线连接器并且包括形成在其中的电接触区域，并且当连接器接合在内腔内时，该内部定位成与连接器焊盘阵列中的一个连接，以便于电连接选择的电极对应于所述连接器焊盘阵列中的一个。

9. 发明申请

WO2003092801A1 APPARATUS AND METHOD FOR FIXEDLY ENGAGING AN IMPLANTABLE ELECTRICAL LEAD 审中-公开
标题翻译：固定接合可植入电线的装置和方法
公开(公告)号：WO2003092801A1
公开(公告)日：2003-11-13
申请号：PCT/US2003/009631
申请日：2003-03-28
申请人： MEDTRONIC, INC.
发明人： KUPPER, Bernhard , HINE, Douglas, S. , SOMMER, John, L. , BJORKLUND, Vicki, L.
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61N2001/0578
摘要： An electrical lead (120) includes an elongate body (106) having a proximal end and a fixation member (206) joined to the elongate body and distally disposed from the proximal end of the elongate body, wherein the fixation member is capable of being extended from and retracted toward the elongate body. A method for fixedly engaging said lead includes advancing an electrical lead into vasculature and extending a fixation member from the body of the electrical lead to fixedly engage the electrical lead within the vasculature. The method may further include retracting the fixation member toward the body of the electrical lead to unengagethe electrical lead within the vasculature and retracting the electrical lead from the vasculature.
摘要翻译：电引线（120）包括细长体（106），其具有近端和固定构件（206），固定构件（206）连接到细长主体并且从细长体的近端向远侧设置，其中固定构件能够延伸从细长体伸出并缩回。用于固定地接合所述引线的方法包括使电引线进入脉管系统并且从电引线的主体延伸固定构件以固定地接合脉管内的电引线。该方法还可以包括将固定构件朝向电引线的主体缩回，以使血管内的电引线不起作用，并将电引线从脉管系统收回。

10. 发明申请

WO2003092800A1 METHOD AND APPARATUS FOR PLACING A LEAD WITH ADJUSTABLE ELECTRODE SPACING 审中-公开
标题翻译：用于配置可调节电极间隔的引线的方法和装置
公开(公告)号：WO2003092800A1
公开(公告)日：2003-11-13
申请号：PCT/US2003/010091
申请日：2003-04-02
申请人： MEDTRONIC, INC.
发明人： HINE, Douglas, S. , SOMMER, John, L. , VAUGHAN, James, H. , MCVENES, Rick, D. , GRANDJEAN, Pierre, A. , VAN VENROOIJ, Paulus
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61F2/88 , A61F2/958 , A61N2001/0585
摘要： A medical electrical lead, which may be useful in coupling an implantable medical device (10), is comprised of a first and second lead. The first lead (202) has a first electrode (204) coupled adjacent a distal end portion thereof. The distal end portion of the first lead is anchorable in the coronarysinus of a patient. The second lead (300) is coupled with and moveable along the first lead (202). The second lead has a second electrode (506) located thereon wherein the position of the first and second electrodes may be varied relative to one another by movement of the second lead along the first lead. A rubber tip (516) holds the relative position of each electrode.
摘要翻译：可用于联接可植入医疗装置（10）的医用电线包括第一和第二引线。第一引线（202）具有邻近其远端部分耦合的第一电极（204）。第一引线的远端部分可锚固在患者的冠状动脉内。第二引线（300）与第一引线（202）耦合并可移动。第二引线具有位于其上的第二电极（506），其中第一和第二电极的位置可以通过第二引线沿着第一引线的移动而相对于彼此变化。橡胶尖端（516）保持每个电极的相对位置。

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