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1. 发明申请

WO2022046394A1 MEDICAL DEVICE AND METHOD FOR ENABLING A CARDIAC MONITORING FEATURE 审中-公开
公开(公告)号：WO2022046394A1
公开(公告)日：2022-03-03
申请号：PCT/US2021/045154
申请日：2021-08-09
申请人： MEDTRONIC, INC.
发明人： GALARNEAU, Michelle M. , GREENHUT, Saul E. , GRINBERG, Yanina , SHELDON, Todd J.
IPC分类号： A61N1/365 , A61N1/372 , A61N1/375 , A61B5/00 , A61N1/37
摘要： A medical device is configured to sense a cardiac signal, determine a monitoring metric representative of activity of at least one heart chamber from the sensed cardiac signal, and determine that the monitoring metric meets expected rhythm criteria. The medical device may enable a monitoring feature of the medical device that is based on processing and analysis of the cardiac signal in response to the monitoring metric meeting the expected rhythm criteria.

2. 发明申请

WO2017189802A1 MULTI-THRESHOLD SENSING OF CARDIAC ELECTRICAL SIGNALS IN AN EXTRACARDIOVASCULAR IMPLANTABLE CARDIOVERTER DEFIBRILLATOR 审中-公开
标题翻译：心脏外科植入式心脏起搏器除颤器心脏电信号的多次阈值检测
公开(公告)号：WO2017189802A1
公开(公告)日：2017-11-02
申请号：PCT/US2017/029762
申请日：2017-04-27
申请人： MEDTRONIC, INC.
发明人： CAO, Jian , EBELING, Timothy A. , GREENHUT, Saul E. , HEINKS, Michael W. , SANCHEZ, Irving J. , SOLHEIM, Paul R. , ZHANG, Xusheng , ARNE, Gerald P.
IPC分类号： A61B5/0456 , A61N1/05 , A61N1/362 , A61N1/365 , A61N1/39
摘要： An implantable medical device system capable of sensing cardiac electrical signals includes a sensing circuit, a therapy delivery circuit and a control circuit. The sensing circuit is configured to receive a cardiac electrical signal and sense a cardiac event in response to the signal crossing a cardiac event sensing threshold. The therapy delivery circuit is configured to deliver an electrical stimulation therapy to a patient's heart via the electrodes coupled to the implantable medical device. The control circuit is configured to control the sensing circuit to set a starting value of the cardiac event sensing threshold and hold the starting value constant for a sense delay interval. The control circuit is further configured to detect an arrhythmia based on cardiac events sensed by the sensing circuit and control the therapy delivery circuit to deliver the electrical stimulation therapy in response to detecting the arrhythmia.
摘要翻译：能够感测心电信号的可植入医疗设备系统包括感测电路，治疗传递电路和控制电路。感测电路被配置为接收心脏电信号并且响应于信号越过心脏事件感测阈值来感测心脏事件。治疗递送电路被配置为经由耦合到可植入医疗设备的电极将电刺激治疗递送到患者的心脏。控制电路被配置为控制感测电路设置心脏事件感测阈值的起始值并且将感测延迟间隔中的起始值保持恒定。控制电路还被配置为基于由感测电路感测的心脏事件来检测心律失常，并且响应于检测到心律失常而控制治疗传递电路传递电刺激治疗。

3. 发明申请

WO2016144575A1 MULTI-CHAMBER INTRACARDIAC PACING SYSTEM 审中-公开
标题翻译：多室内吸入系统
公开(公告)号：WO2016144575A1
公开(公告)日：2016-09-15
申请号：PCT/US2016/019889
申请日：2016-02-26
申请人： MEDTRONIC, INC.
发明人： DEMMER, Wade M. , SHELDON, Todd J. , GREENHUT, Saul E. , REINKE, James D.
IPC分类号： A61N1/375 , A61N1/368 , A61N1/372 , A61N1/362 , A61B5/00 , A61B5/0452
CPC分类号： A61N1/3756 , A61B5/0452 , A61B5/4836 , A61B5/686 , A61N1/3622 , A61N1/3682 , A61N1/3688 , A61N1/37205
摘要： The control module of a first pacemaker included in an implantable medical device system including the first pacemaker and a second pacemaker is configured to set a pacing escape interval in response to a far field pacing pulse sensed by the first pacemaker. The far field pacing pulse is a pacing pulse delivered by the second pacemaker. The pacing escape interval is allowed to continue without restarting the in response to a far field intrinsic event sensed by the first pacemaker during the pacing escape interval. The first pacemaker delivers a cardiac pacing pulse to the heart upon expiration of the pacing escape interval.
摘要翻译：包括在包括第一起搏器和第二起搏器的可植入医疗装置系统中的第一起搏器的控制模块被配置为响应于由第一起搏器感测到的远场起搏脉冲设置起搏逃生间隔。远场起搏脉冲是由第二起搏器提供的起搏脉冲。在起搏逃逸间隔期间允许响应于由第一起搏器感测到的远场固有事件而不重新启动起搏逃生间隔。第一个起搏器在起搏逃生间隔期满后向心脏提供心脏起搏脉冲。

4. 发明申请

WO2016064644A1 FILTERING NOISE FROM A SIGNAL SUBJECTED TO BLANKING 审中-公开
标题翻译：从被遮挡的信号中过滤噪声
公开(公告)号：WO2016064644A1
公开(公告)日：2016-04-28
申请号：PCT/US2015/055622
申请日：2015-10-15
申请人： MEDTRONIC, INC.
发明人： HEMMING, Michael T. , GREENHUT, Saul E.
IPC分类号： A61N1/365 , A61N1/37 , A61B5/0428
CPC分类号： A61B5/7203 , A61B5/04012 , A61B5/0402 , A61B5/0452 , A61B5/0538 , A61B5/1107 , A61B5/686 , A61N1/365 , A61N1/3718
摘要： The disclosure describes techniques and systems for filtering noise from a physiological signal. In one example, one or more processors are configured to receive a signal indicative of physiological activity of a patient, wherein the signal comprises noise at one or more frequencies, and filter the noise from the signal according to a noise rejection model, wherein the noise rejection model predicts the noise at the one or more frequencies. The one or more processors may also be configured to, responsive to initiation of a blanking period for the signal, advance the noise rejection model in time during the blanking period, and, responsive to termination of the blanking period, filter, based on the noise rejection model advanced in time, the noise at the one or more frequencies from the signal.
摘要翻译：本公开描述了用于从生理信号滤波噪声的技术和系统。在一个示例中，一个或多个处理器被配置为接收指示患者的生理活动的信号，其中所述信号包括一个或多个频率的噪声，并且根据噪声抑制模型对来自信号的噪声进行滤波，其中噪声拒绝模型预测在一个或多个频率的噪声。一个或多个处理器还可以被配置为响应于信号的消隐周期的启动，在消隐期间及时推进噪声抑制模型，并且响应消隐周期的终止，基于噪声进行滤波拒绝模式及时提前，噪声在一个或多个频率的信号。

5. 发明申请

WO2016014330A1 SYSTEM AND METHOD FOR TRIGGERED PACING 审中-公开
标题翻译：触发的系统和方法
公开(公告)号：WO2016014330A1
公开(公告)日：2016-01-28
申请号：PCT/US2015/040713
申请日：2015-07-16
申请人： MEDTRONIC, INC.
发明人： GREENHUT, Saul E. , CARNEY, James K.
IPC分类号： A61N1/372 , A61N1/375 , A61N1/362
CPC分类号： A61N1/365 , A61N1/3621 , A61N1/3622 , A61N1/37205 , A61N1/37211 , A61N1/37288 , A61N1/3756
摘要： A medical device system including an intracardiac pacemaker is configured to receive by an implantable medical device sensing module a first cardiac signal using a first pair of electrodes implanted outside the cardiovascular system and identify a P-wave from the first cardiac signal. The system transmits a wireless trigger signal to the intracardiac pacemaker in response to identifying the P-wave. The intracardiac pacemaker delivers a pacing therapy in response to the trigger signal.
摘要翻译：包括心内心脏起搏器的医疗装置系统被配置为使用植入在心血管系统外部的第一对电极并且从第一心脏信号识别P波，由可植入医疗装置感测模块接收第一心脏信号。响应于识别P波，系统向心脏起搏器发送无线触发信号。心脏起搏器响应于触发信号提供起搏治疗。

6. 发明申请

WO2015164295A1 METHOD AND APPARATUS FOR ADJUSTING A BLANKING PERIOD FOR SELECTING A SENSING VECTOR CONFIGURATION IN A MEDICAL DEVICE 审中-公开
标题翻译：用于调整用于在医疗设备中选择感测矢量配置的空白期的方法和装置
公开(公告)号：WO2015164295A1
公开(公告)日：2015-10-29
申请号：PCT/US2015/026745
申请日：2015-04-21
申请人： MEDTRONIC, INC.
发明人： GREENHUT, Saul E. , STADLER, Robert W. , ZHANG, Xusheng
IPC分类号： A61B5/0456 , A61N1/362 , A61B5/042 , A61B5/04
CPC分类号： A61B5/04011 , A61B5/0408 , A61B5/042 , A61B5/0456
摘要： A method and medical device for determining sensing vectors that includes sensing cardiac signals from a plurality of electrodes, the plurality of electrodes forming a plurality of sensing vectors, setting a blanking period and a blanking period adjustment window for the plurality of sensing vectors in response to the sensed cardiac signals, determining first signal differences during the blanking period adjustment window, and adjusting the blanking period in response to the determined first signal differences.
摘要翻译：一种用于确定感测向量的方法和医疗装置，其包括感测来自多个电极的心脏信号，所述多个电极形成多个感测向量，响应于所述多个感测向量设置消隐周期和多个感测向量的消隐周期调整窗口感测到的心脏信号，在消隐期调整窗口期间确定第一信号差，并响应于所确定的第一信号差调整消隐周期。

7. 发明申请

WO2022115217A1 DEVICE AND METHOD FOR ATRIAL TACHYARRHYTHMIA DETECTION 审中-公开
公开(公告)号：WO2022115217A1
公开(公告)日：2022-06-02
申请号：PCT/US2021/057927
申请日：2021-11-03
申请人： MEDTRONIC, INC.
发明人： GREENHUT, Saul E. , GANION, Vincent P. , GRINBERG, Yanina , MATTSON, Alexander R.
IPC分类号： A61B5/363 , A61B5/00 , A61N1/05
摘要： A medical device is configured to sense an acceleration signal and determine at least one frequency metric from the acceleration signal that is correlated to a frequency of oscillations of the acceleration signal. The medial device is configured to determine that the at least one frequency metric meets atrial tachyarrhythmia criteria and detect an atrial tachyarrhythmia in response to at least the frequency metric meeting the atrial tachyarrhythmia criteria.

8. 发明申请

WO2018140343A1 DETECTION OF ELECTROMAGNETIC INTERFERENCE IN A CARDIAC ELECTRICAL SIGNAL BY AN IMPLANTABLE MEDICAL DEVICE 审中-公开
公开(公告)号：WO2018140343A1
公开(公告)日：2018-08-02
申请号：PCT/US2018/014648
申请日：2018-01-22
申请人： MEDTRONIC, INC.
发明人： ZHANG, Xusheng , GREENHUT, Saul E. , HEINKS, Michael W. , SOLHEIM, Paul R.
IPC分类号： A61N1/39 , A61N1/37
摘要： A medical device, such as an implantable cardioverter defibrillator (ICD), starts a timer set to a time interval in response to a cardiac electrical signal crossing a noise threshold amplitude and resets the timer to the time interval in response to each crossing of the noise threshold amplitude by the cardiac electrical signal that occurs prior to the time interval expiring. A control circuit of the medical device determines a parameter of the behavior of the timer and identifies a sensed cardiac event as an electromagnetic interference (EMI) event based on the parameter. The medical device may detect EMI in response to the EMI event and withhold a tachyarrhythmia detection or therapy in response to EMI detection.

9. 发明申请

WO2018022422A1 CARDIAC ELECTRICAL SIGNAL NOISE DETECTION FOR TACHYARRHYTHMIA EPISODE REJECTION 审中-公开
标题翻译：心律失常性心律失常的心电图信号噪声检测
公开(公告)号：WO2018022422A1
公开(公告)日：2018-02-01
申请号：PCT/US2017/043081
申请日：2017-07-20
申请人： MEDTRONIC, INC.
发明人： GREENHUT, Saul E. , CAO, Jian , ZHANG, Xusheng
IPC分类号： A61N1/02 , A61N1/39 , A61N1/365 , A61N1/37 , A61N1/05 , A61B5/042
摘要： A medical device, such as an extra-cardiovascular implantable cardioverter defibrillator (ICD), senses R-waves from a first cardiac electrical signal by a first sensing channel and stores a time segment of a second cardiac electrical signal acquired by a second sensing channel in response to each sensed R-wave. The medical device determines at least one noise parameter from a group of the stored time segments of the second cardiac electrical signal, detects noise based on the noise parameter, and withholds detection of a tachyarrhythmia episode in response to detecting the noise.
摘要翻译：诸如额外心血管植入式心脏复律除颤器（ICD）之类的医疗设备通过第一感测通道感测来自第一心脏电信号的R波并且存储第二心脏电信号的时间段信号，其响应于每个感测的R波而由第二感测通道采集。医疗设备从第二心电信号的一组存储的时间段中确定至少一个噪声参数，基于噪声参数检测噪声，并且响应于检测到噪声而阻止检测到快速性心律失常事件。

10. 发明申请

WO2016172080A1 METHOD AND APPARATUS FOR DETECTION OF INTRINSIC DEPOLARIZATION FOLLOWING HIGH ENERGY CARDIAC ELECTRICAL STIMULATION 审中-公开
标题翻译：用于检测高能量心脏电刺激的内在分解的方法和装置
公开(公告)号：WO2016172080A1
公开(公告)日：2016-10-27
申请号：PCT/US2016/028246
申请日：2016-04-19
申请人： MEDTRONIC, INC.
发明人： GREENHUT, Saul E. , HEMMING, Michael T.
IPC分类号： A61N1/362 , A61N1/39 , A61N1/37 , A61B5/0452 , G06K9/00
CPC分类号： A61N1/3702 , A61B5/021 , A61B5/04085 , A61B5/0422 , A61B5/0452 , A61B5/0456 , A61B5/0464 , A61B5/1118 , A61B5/686 , A61N1/3621 , A61N1/3622 , A61N1/3625 , A61N1/371 , A61N1/3925 , A61N1/3956 , A61N1/3962 , G06K9/0053 , G06K9/00543
摘要： A medical device is configured to deliver a high-energy electrical stimulation pulse to a patient that produces a post-stimulation polarization signal. A cardiac signal analyzer of the medical device is configured to detect a cardiac electrical signal superimposed on the post-stimulation polarization signal, determine at least one feature of the detected cardiac electrical signal, compare the feature to criteria that differentiate an intrinsic cardiac event during the post-stimulation polarization signal from an evoked response signal and identify the detected cardiac electrical signal as the intrinsic cardiac event if the feature meets the criteria.
摘要翻译：医疗设备被配置为向产生刺激后的极化信号的患者传送高能电刺激脉冲。医疗装置的心脏信号分析器被配置为检测叠加在刺激后极化信号上的心电信号，确定检测到的心电信号的至少一个特征，将该特征与区分在来自诱发响应信号的刺激后极化信号，并且如果特征满足标准，则将检测到的心电信号识别为内在心脏事件。

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