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1. 发明申请

WO2008004069A3 SYSTEM AND METHOD FOR DELIVERING A BIFURCATED STENT 审中-公开
标题翻译：用于传递分支的系统和方法
公开(公告)号：WO2008004069A3
公开(公告)日：2009-08-27
申请号：PCT/IB2007001792
申请日：2007-06-29
申请人： MEDINOL LTD , RICHTER JACOB
发明人： RICHTER JACOB
IPC分类号： A61F2/82
CPC分类号： A61F2/856 , A61F2/07 , A61F2/82 , A61F2/954 , A61F2/958 , A61F2230/001
摘要： A system and method for delivering and assembling a bifurcated stent in a bifurcated vessel having a first lumen and a second lumen. The system and method includes the use of three balloon catheters wherein at least one of the catheters is a fixed wire catheter. A first segment of the bifurcated stent having a stem portion, a first leg portion, a longitudinal bore extending therethrough and a branch aperture formed in the side wall is mounted on two of the balloon catheters and delivered to the treatment site where it is implanted into the first lumen. A second segment of the bifurcated stent having a proximal end, a distal end and a longitudinal bore extending therethrough is mounted on the third balloon catheter and is delivered to the treatment site such that the distal end extends into the second lumen and the proximal end extends into longitudinal bore of the first segment. The second segment is then implanted into the second lumen and secured to the branch aperture of the first segment to form a bifurcated stent.
摘要翻译：一种用于在具有第一腔和第二腔的分叉血管中输送和组装分叉支架的系统和方法。该系统和方法包括使用三个气囊导管，其中至少一个导管是固定导线导管。分叉支架的第一段具有杆部，第一腿部，延伸穿过其中的纵向孔和形成在侧壁中的分支孔安装在两个气囊导管上，并被输送到其植入的治疗部位第一个流明。具有近端，远端和延伸通过其延伸的纵向孔的分叉支架的第二段安装在第三气囊导管上并被输送到治疗部位，使得远端延伸到第二腔中，并且近端延伸进入第一段的纵向孔。然后将第二段植入第二腔并固定到第一段的分支孔，以形成分叉支架。

2. 发明申请

WO2006111801A3 A COVERING FOR AN ENDOPROSTHETIC DEVICE AND METHODS OF USING FOR ANEURYSM TREATMENT 审中-公开
标题翻译：内窥镜装置的覆盖及其用于治疗神经病的方法
公开(公告)号：WO2006111801A3
公开(公告)日：2008-11-27
申请号：PCT/IB2006000471
申请日：2006-03-03
申请人： MEDINOL LTD , RICHTER JACOB
发明人： RICHTER JACOB
IPC分类号： A61M29/00 , A61F2/07 , A61F2/91
CPC分类号： A61B17/12022 , A61B17/12118 , A61B17/1215 , A61F2/07 , A61F2/90 , A61F2/91 , A61F2002/075 , A61F2250/0023
摘要： The present invention relates to covered endoprosthetic devices. Covered endoprosthetic devices comprise an endoprosthesis and a sheath. The sheath comprises a central portion and outer portions, wherein the central portion preferentially restricts or causes a restriction of blood flow. Blood flow can be reduced by the central portion of the sheath by varying the permeability of the sheath or by having projections on the sheath that slow blood flow. Permeability may be provided by perforations or holes in the material of the sheath or by varying the polymer structure that makes up the sheath itself. The outer portions of the sheath do not substantially reduce blood flow. Methods of using sheath-covered endoprosthetic devices of the invention to treat aneurysms, especially aneurysms in proximity to small perforator vessels or arteries, are also encompassed.
摘要翻译：本发明涉及覆盖的假体内装置。覆盖的假体内装置包括内假体和护套。护套包括中心部分和外部部分，其中中心部分优先限制或导致血流的限制。通过改变护套的渗透性或通过在鞘上具有减慢血液流动的突起，可以通过鞘的中心部分减少血液流动。渗透性可以通过护套材料中的穿孔或孔提供，或通过改变构成护套本身的聚合物结构来提供。护套的外部部分基本上不减少血流量。还包括使用本发明的护套覆盖的假体内装置来治疗动脉瘤，特别是小穿孔器或动脉附近的动脉瘤的方法。

3. 发明申请

WO2007099439A2 STENT WITH VARIABLE FEATURES TO OPTIMIZE SUPPORT AND METHOD OF MAKING SUCH STENT 审中-公开
标题翻译：具有可变特性以优化支持的STENT和制造这种支架的方法
公开(公告)号：WO2007099439A2
公开(公告)日：2007-09-07
申请号：PCT/IB2007000482
申请日：2007-02-28
申请人： MEDINOL LTD , RICHTER JACOB
发明人： RICHTER JACOB
IPC分类号： A61F2/84 , A61F2/00 , A61F2/02 , A61F2/06 , A61F2/82 , A61F2/90 , A61M5/00 , A61M29/00
CPC分类号： A61F2/91 , A61F2/915 , A61F2002/91533 , A61F2002/91541 , A61F2002/91558 , A61F2230/0054 , A61F2250/0018 , A61F2250/0029
摘要： An intravascular stent especially suited for implanting in lumens having variable characteristics such as curvatures, changing diameters as found in ostial regions or variable wall compliance during systolic cycles. The stent can include an end region which is fabricated to have a greater radial strength than the remaining axial length of the stent. Such a stent is particularly suited for use in ostial regions, which require greater support near the end of the stent. The stent alternatively can include sections adjacent the end of the stent with greater bending flexibility than the remaining axial length of the stent. Such a stent is particularly suited for use in curved arteries. The stent can be constructed with an end that has greater radial strength and sections adjacent the end with greater bending flexibility. Such a stent prevents flaring of the stent end during insertion. The stent can also be constructed to have increased longitudinal flexibility when expanded such that it flexes with the vessel wall during systolic cycles.
摘要翻译：一种血管内支架，特别适用于植入具有可变特征（例如曲率），腔内变化的直径或在收缩期循环期间可变壁依从性的腔内。支架可以包括制造成具有比支架的剩余轴向长度更大的径向强度的端部区域。这种支架特别适用于在支架端部附近需要较大支撑的口部区域。替代地，支架可以包括邻近支架的端部的部分，其具有比支架的剩余轴向长度更大的弯曲柔性。这种支架特别适用于弯曲的动脉。支架可以构造成具有较大径向强度的端部和邻近端部的部分，具有较大的弯曲柔性。这种支架可防止插入期间支架端部的扩张。支架也可以被构造成在膨胀时具有增加的纵向柔性，使得其在收缩期循环期间与血管壁弯曲。

4. 发明申请

WO2005118971A3 HYBRID STENT 审中-公开
标题翻译：混合型
公开(公告)号：WO2005118971A3
公开(公告)日：2006-06-22
申请号：PCT/IB2005001524
申请日：2005-05-31
申请人： MEDINOL LTD , RICHTER JACOB
发明人： RICHTER JACOB
IPC分类号： A61F2/00 , A61F2/02 , A61F2/82 , E04B1/82 , E04B2/02 , F01N1/00
CPC分类号： A61F2/82 , A61F2/91 , A61F2/915 , A61F2002/826 , A61F2002/828 , A61F2002/91541 , A61F2002/91558 , A61F2210/0004 , A61F2250/0031 , A61F2250/0071
摘要： A stent (30) is provided with a series of short pieces (34) or sections connected together by a bioresorbable polymer (36). The stent sections are designed to separate or articulate with time as the polymer biodegrades. The time of separation can be controlled by the characteristics of the bioresorbable polymer to allow the stent to be buried in neo-intima. By using a tube (32) made of a bioresorbable polymer, the continuous covering of the tubing may inhibit embolization in the first few weeks after stent implantation within the walls of a vessel and timing for removal of the tube through formulation of the bioresorbable polymer can be controlled to occur when embolization is no longer a risk. When the detachment of the stent pieces or sections occurs, they are fixedly secured within the vessel and each are able to flex with the vessel independently of the other stent segments.
摘要翻译：支架（30）设置有一系列短块（34）或通过生物可再吸收聚合物（36）连接在一起的部分。支架部分设计成随着聚合物的生物降解而与时间分离或关节。分离时间可以通过生物可吸收聚合物的特性来控制，以允许支架埋入新内膜。通过使用由生物可再吸收的聚合物制成的管（32），管的连续覆盖物可以在支架植入在血管壁内的最初几周内抑制栓塞，并且通过制备可生物再吸收的聚合物罐来移除管的时机当栓塞不再是风险时，控制发生。当发生支架片或部分的分离时，它们被固定地固定在容器内，并且每个能够独立于其它支架段与血管弯曲。

5. 发明申请

WO2005076691A2 LONGITUDINALLY FLEXIBLE STENT 审中-公开
标题翻译：长期灵活的STENT
公开(公告)号：WO2005076691A2
公开(公告)日：2005-08-25
申请号：PCT/IB2004004283
申请日：2004-12-21
申请人： MEDINOL LTD , RICHTER JACOB
发明人： RICHTER JACOB
IPC分类号： A61F2/00
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91508 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2230/0054
摘要： An intravascular stent especially suited for implanting in curved arterial portion. The stent retains longitudinal flexibility after expansion. The stent is formed of intertwined meander patterns forming triangular cells. The cells are adapted to provide radial support, and also provide longitudinal flexibility after expansion. The cells also provide increase coverage of a vessel wall. Loops in the stent are disposed and adapted to cooperate, so that after expansion of said stent within a curved lumen, the stent is curved and cells on the outside of the curve open in length, but narrow in width, whereas cells on the inside of the curve shorten in length, but thicken in width to maintain a density of the stent element area which is much more constant than otherwise between the inside and outside of the curve. The stent also minimizes flaring out by eliminating free loops of the radially supporting circumferential bands of loops.
摘要翻译：血管内支架，特别适用于植入弯曲的动脉部分。支架在扩张后保持纵向弹性。支架由形成三角形细胞的相互缠绕的曲折形图形成。电池适于提供径向支撑，并且还在膨胀后提供纵向柔性。细胞还提供了血管壁的增加的覆盖。支架中的环路被布置并适于配合，使得在支架在弯曲内腔中膨胀之后，支架是弯曲的，并且曲线外侧的细胞的长度开放但宽度窄，而内侧的细胞该曲线长度缩短，但是宽度增加以保持支架元件面积的密度，其在曲线的内部和外部之间比其它情况更加恒定。支架还通过消除径向支撑的圆周环带的自由环来最小化扩口。

6. 发明申请

WO02094128A2 LONGITUDINALLY FLEXIBLE STENT 审中-公开
标题翻译：长期灵活的STENT
公开(公告)号：WO02094128A2
公开(公告)日：2002-11-28
申请号：PCT/IB0201746
申请日：2002-05-21
申请人： MEDINOL LTD , PINCHASIK GREGORY , RICHTER JACOB
发明人： PINCHASIK GREGORY , RICHTER JACOB
IPC分类号： A61F2/84 , A61F2/06 , A61F2/90 , A61F
CPC分类号： A61F2/91 , A61F2/915 , A61F2002/91508 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2230/0054
摘要： An intravascular stent especially suited for implanting in curved arterial portions. The stent retains longitudinal flexibility after expansion. The stent includes a plurality of first circumferential bands containing a pattern of loops at a first frequency and a plurality of second circumferential bands containing a pattern of loops at a second frequency higher than said first frequency, alternating with said first circumferential bands and periodically coupled thereto to form cells. The high frequency elements provide a flexibility after expansions which can be repeatedly stress by the beating heart, with out exceeding the elastic limit of the stent material.
摘要翻译：一种特别适合植入弯曲动脉部分的血管内支架。支架在扩张后保持纵向弹性。所述支架包括多个第一周期带，所述第一周向带包含第一频率的线圈图案，以及多个第二周向带，其包含高于所述第一频率的第二频率的环路图案，与所述第一周向带交替并周期性耦合形成细胞。高频元件在膨胀之后提供柔性，其可以通过跳动的心脏重复应力，超出支架材料的弹性极限。

7. 发明申请

WO0195833A3 TWO BALLOON CATHETER FOR STAGED STENT EXPANSION 审中-公开
标题翻译：两个膨胀膨胀的膨胀管
公开(公告)号：WO0195833A3
公开(公告)日：2002-06-06
申请号：PCT/IL0100543
申请日：2001-06-13
申请人： MEDINOL LTD , RICHTER JACOB
发明人： RICHTER JACOB
IPC分类号： A61F2/958 , A61M25/00 , A61F2/06 , A61M25/10
CPC分类号： A61F2/958
摘要： A catheter with two balloons for implanting a stent without flaring at the ends of the stent during implantation has an outer balloon overlying an inner balloon. The length of the inner balloon is shorter than the length of the outer balloon and shorter than a stent which is mounted over both balloons. Upon inflation of the inner balloon, the inner balloon expands only the center of the stent. After the center of the stent is expanded, further application of pressure bursts the inner balloon allowing application of pressure to the outer balloon. The outer balloon is then inflated, expanding the ends of the stent.
摘要翻译：具有两个气球的导管，用于在植入期间用于植入支架的端部而不扩张的支架具有覆盖在内气囊上的外气球。内球囊的长度比外球囊的长度短，并且比安装在两个气球上的支架短。内气囊膨胀时，内囊仅扩张支架的中心。在扩张支架的中心之后，进一步施加压力可使内球囊爆裂，从而向外球囊施加压力。然后使外球囊膨胀，扩张支架的端部。

8. 发明申请

WO0193777A3 SERPENTINE COILED LADDER STENT 审中-公开
标题翻译： SERPENTINE卷绕梯子
公开(公告)号：WO0193777A3
公开(公告)日：2002-05-16
申请号：PCT/IL0100518
申请日：2001-06-05
申请人： MEDINOL LTD , RICHTER JACOB , PINCHASIK GREGORY
发明人： RICHTER JACOB , PINCHASIK GREGORY
IPC分类号： A61F2/84 , A61F2/02 , A61F2/82 , A61F2/88 , A61F2/90 , A61M29/00 , A61F2/06
CPC分类号： A61F2/88 , A61F2/91 , A61F2/915 , A61F2002/91508 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/9155
摘要： A serpentine coiled ladder stent (30) is provided, in which the coil is formed from a wound strip of cells (37), wherein the sides (34, 35) of the cells (37) are serpentine windings, wherein the strip is formed of at least two side bands (34, 35) connected to each other, for example by a series of cross struts (36). The cross struts (36) may be positioned slightly askew. Each side band (34, 35) is formed in a serpentine pattern comprising a series of bends (38), wherein upon expansion of the stent (30), the bends (38) of the side bands (34, 35) open to increase the length of each of the individual cells (37) in the helical direction, thereby lengthening the strip in the helical direction to allow the stent (30) to expand without any significant unwinding of the strip.
摘要翻译：提供了蛇形盘绕的梯形支架（30），其中线圈由一个单元（37）的缠绕条形成，其中该单元（37）的侧面（34,35）是蛇形绕组，其中形成该条带至少两个彼此连接的边带（34,35），例如通过一系列交叉支柱（36）。交叉支柱（36）可以稍微偏斜地定位。每个侧带（34,35）形成为包括一系列弯曲部（38）的蛇形图案，其中在支架（30）膨胀时，侧带（34,35）的弯曲部（38）打开以增加每个单个细胞（37）的长度在螺旋方向上，从而使条带沿螺旋方向延长以允许支架（30）膨胀而没有带的任何明显的退绕。

9. 发明申请

WO0189409A2 BIFURCATED STENT WITH IMPROVED SIDE BRANCH APERTURE AND METHOD OF MAKING SAME 审中-公开
标题翻译：具有改进的侧支撑孔的分叉杆及其制造方法
公开(公告)号：WO0189409A2
公开(公告)日：2001-11-29
申请号：PCT/IL0100456
申请日：2001-05-21
申请人： MEDINOL LTD , RICHTER JACOB , PINCHASIK GREGORY
发明人： RICHTER JACOB , PINCHASIK GREGORY
IPC分类号： A61F2/00 , A61F2/06 , A61F2/82 , A61M29/00 , A61F
CPC分类号： A61F2/856 , A61F2/07 , A61F2/82 , A61F2/852 , A61F2/90 , A61F2/91 , A61F2/915 , A61F2/954 , A61F2/958 , A61F2002/065 , A61F2002/067 , A61F2002/075 , A61F2002/91533 , A61F2002/91558 , A61F2220/0041 , A61F2220/0058 , A61F2230/001 , A61F2240/001 , A61F2250/006 , Y10S623/901 , Y10T29/496 , Y10T29/49826
摘要： A stent (5) for insertion into a blood vessel is made from a sheet having a longitudinal axis and a first portion (10) and a second portion (30). The first portion (10) has a proximal end and a distal end and a first lateral side and a second lateral side with the lateral sides of the first portion substantially parallel to the longitudinal axis and disposed apart from each other a first distance. The second portion (30) has a proximal end (16) and a distal end (17) and a first lateral side and a second lateral side with the lateral sides of the second portion substantially parallel to the longitudinal axis and disposed apart from each other a second distance that is less than the first distance. The proximal end (16) of the second portion (30) communicates with the distal end of the first portion. The first lateral side of the first portion is connected to the second lateral side of the first portion and the first lateral side of the second portion is connected to the second lateral side of the second portion to form the stent. A portion of the distal end of the first portion and a portion of the proximal end of the second portion define a branch aperture.
摘要翻译：用于插入血管的支架（5）由具有纵向轴线的片材和第一部分（10）和第二部分（30）制成。第一部分（10）具有近端和远端以及第一侧面和第二横向侧面，其中第一部分的侧面基本上平行于纵向轴线并且彼此分开设置第一距离。第二部分（30）具有近端（16）和远端（17）以及第一横向侧和第二侧面，其中第二部分的侧边基本上平行于纵向轴线并彼此分开设置第二距离小于第一距离。第二部分（30）的近端（16）与第一部分的远端连通。第一部分的第一侧面连接到第一部分的第二侧面，并且第二部分的第一侧面与第二部分的第二横向侧连接以形成支架。第一部分的远端的一部分和第二部分的近端的一部分限定分支孔。

10. 发明申请

WO2009007850A3 HYBRID STENT HAVING A FIBER OR WIRE BACKBONE 审中-公开
标题翻译：具有纤维或电线背板的混合动力
公开(公告)号：WO2009007850A3
公开(公告)日：2010-03-25
申请号：PCT/IB2008002515
申请日：2008-03-26
申请人： MEDINOL LTD , RICHTER JACOB
发明人： RICHTER JACOB
IPC分类号： A61L31/02 , A61F2/82 , A61L31/04 , A61L31/14
CPC分类号： A61F2/91 , A61F2/915 , A61F2002/828 , A61F2002/91541 , A61F2210/0004 , A61F2250/0071 , A61L31/022 , A61L31/042 , A61L31/148 , C08L67/00
摘要： A stent is provided with a series of short pieces or sections connected together by at least one polymer fiber or wire. The polymer fiber or wire can be biodegradable or durable. The fiber polymers may also contain beads, blobs and bulges in the fibers. The stent sections are designed to separate or articulate with time as the body lumen moves in response to biological and physiological events.
摘要翻译：支架设置有通过至少一种聚合物纤维或线连接在一起的一系列短片或片段。聚合物纤维或线可以是可生物降解的或耐久的。纤维聚合物还可以在纤维中含有珠粒，斑点和凸起。支架部分设计成随着体腔随着生理和生理事件而移动而随时间分离或关节。

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