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    • 2. 发明申请
    • CONTAINER AND ONE-WAY VALVE ASSEMBLY FOR STORING AND DISPENSING SUBSTANCES, AND RELATED METHOD
    • 用于储存和分配物质的集装箱和单向阀组件及相关方法
    • WO2005058743A3
    • 2006-04-20
    • PCT/US2004041369
    • 2004-12-10
    • MEDICAL INSTILL TECH INCPY DANIEL CCHAN JULIAN VRODRIGUEZ GIOVANNI
    • PY DANIELCHAN JULIAN VRODRIGUEZ GIOVANNI
    • B65D47/20B65D51/22B67D7/74B67D99/00B67D5/00
    • B65D51/226B65D47/2075
    • A device for storing and dispensing a substance includes a container having a body defining therein a storage chamber for receiving and storing the substance. The container includes a head located at one end of the body and a first passageway that is in fluid communication with the storage chamber of the body and defines a flow path therebetween. The container also includes a pierceable wall located on an opposite side of the passageway relative to the storage chamber, and a first connecting portion for connecting another component thereto. The device also includes a one-way valve assembly that includes a valve body including a body base defining a second passageway and at least one piercing portion engageable with the pierceable wall of the container. The valve assembly includes a second connecting portion that is connectable to the first connecting portion of the container for fixedly securing the valve assembly to the container.
    • 用于存储和分配物质的装置包括具有在其中限定有用于接收和存储物质的储存室的主体的容器。 容器包括位于主体一端的头部和与主体的储存室流体连通并限定其间的流路的第一通道。 容器还包括位于通道相对于储存室的相对侧上的可穿透壁,以及用于将另一部件连接到其上的第一连接部分。 该装置还包括单向阀组件,该单向阀组件包括阀体,该阀体包括限定第二通道的主体基座和与容器的可刺穿壁可接合的至少一个穿孔部分。 阀组件包括可连接到容器的第一连接部分的第二连接部分,用于将阀组件固定地固定到容器。
    • 5. 发明申请
    • DISPENSER AND APPARATUS FOR FILLLING A DISPENSER
    • 用于填充分配器的分配器和装置
    • WO2004101027A3
    • 2005-11-10
    • PCT/US2004014823
    • 2004-05-12
    • MEDICAL INSTILL TECH INCPY DANIEL CCHAN JULIAN V
    • PY DANIELCHAN JULIAN V
    • A61M20060101B65B1/04B65B3/30
    • B65D83/62A61J1/00A61J1/1443B65B3/30B65B31/044B65D83/425
    • A dispenser for holding multiple doses of fluids or other substances, and for dispensing the substances, has a vial, a flexib e ~ adder received within the vial, and a variable volume storage chamber formed between the bladder and vial. A filling valve is coupled in fluid communication 5 with the storage chamber and ~eSnes (1) a normally closed, fluid-tight position hermetically sealing the storage chamber from the ambient atmosphere, and (2) an open position allowing the passage of fluid through the valve both to evacuate the storage chamber and to introduce fluid through the valve to 511 the storage chamber. A pump is coupled in fluid communication with the storage chamber for pumping fluids out of the storage chamber. A dispensing valve is coupled in 10 fluid communication with the pump and defines (1) a normally closed, fluid-tight position preventing the passage of fluid out of the dispenser, and (2) an open position for dispensing pumped fluid therethrough
    • 用于保持多个剂量的流体或其他物质并用于分配物质的分配器具有容纳在小瓶内的小瓶,柔性加热器以及形成在囊和小瓶之间的可变体积存储室。 填充阀与储存室流体连通5连接,并且〜(1)常闭密封的流体密封位置将储存室与环境大气密封,以及(2)允许流体通过的打开位置 所述阀都将所述储存室抽真空并将流体通过所述阀导入所述储存室。 泵与储存室流体连通地联接,用于将流体泵出储存室。 分配阀与泵连通10流体连通并且限定(1)常闭的流体密封位置,防止流体从分配器通过,以及(2)用于分配泵送的流体通过的打开位置
    • 6. 发明申请
    • ONE-WAY VALVE, APPARATUS AND METHOD OF USING THE VALVE
    • 单向阀,装置和使用阀的方法
    • WO2006063000A9
    • 2006-07-20
    • PCT/US2005044167
    • 2005-12-05
    • MEDICAL INSTILL TECH INCPY DANIEL CCHAN JULIAN VADAMO BENOIT
    • PY DANIELCHAN JULIAN VADAMO BENOIT
    • G06Q10/00A23L23/00
    • B67D1/0004B65B39/004B67D1/0007B67D1/0009B67D1/0082B67D1/10B67D1/108B67D1/1279B67D3/04B67D2001/0827F04B43/1238F04B53/1037Y10T137/7761
    • An apparatus has a valve body defining a first passageway, a valve seat, and a flow aperture extending through the valve body and coupled in fluid communication with the first passageway. A valve cover of the apparatus is formed of an elastic material and includes a cover base mounted on the valve body and fixedly secured against movement relative thereto, and a valve portion overlying the valve seat. The valve portion defines a predetermined radial thickness and forms an interference fit with the valve seat. The valve portion and the valve seat define a normally closed, axially-extending valve opening therebetween. The valve portion is movable between a normally closed position with the valve portion engaging the valve seat, and an open position with at least a segment of the valve portion spaced away from the valve seat to connect the valve opening in fluid communication with the flow aperture to thereby allow the passage of fluid from the flow aperture through the valve opening. A hermetically sealed variable-volume storage chamber stores therein multiple portions of the fluid and is connectible in fluid communication with the one-way valve assembly. A pump is coupled between the variable-volume storage chamber and the one-way valve assembly, and is configured to pump discrete portions of fluid from the variable­volume storage chamber, through the flow aperture, and through the valve opening to dispense the portions of fluid through the valve assembly.
    • 一种装置具有限定第一通道,阀座和延伸穿过阀体并与第一通道流体连通地联接的流动孔的阀体。 该装置的阀盖由弹性材料形成,并且包括安装在阀体上的盖基座,并且固定地抵靠其相对移动,以及覆盖在阀座上的阀部分。 阀部分限定预定的径向厚度并与阀座形成过盈配合。 阀部分和阀座限定了其间的常闭的,轴向延伸的阀开口。 阀部分可以在与阀座接合的阀部分的常闭位置和打开位置之间移动,打开位置具有与阀座间隔开的阀部分的至少一段,以连接与开口流体连通的阀开口 从而允许流体从流动孔通过阀开口。 气密密封的可变容积储存室在其中存储有多个流体部分,并可与单向阀组件流体连通。 泵连接在可变体积存储室和单向阀组件之间,并且构造成泵送来自可变容积存储室的离散部分的流动孔,并且通过阀开口以分配流体的一部分 通过阀门组件。
    • 7. 发明申请
    • DELIVERY DEVICE AND METHOD OF DELIVERY
    • 交付设备和交付方法
    • WO2005048875A3
    • 2006-06-29
    • PCT/US2004038345
    • 2004-11-15
    • MEDICAL INSTILL TECH INCPY DANIEL CCHAN JULIAN VATWOOD JEFFREY M
    • PY DANIELCHAN JULIAN VATWOOD JEFFREY M
    • A61F20060101A61F9/00A61M35/00
    • B05B11/007A61F9/0008A61M11/007A61M15/08A61M35/003A61M2210/0612B05B11/0043B05B11/0048B05B11/0056B05B11/0072B05B11/3004B05B11/3056B05B11/307B05B11/3074B05B11/3077
    • An ophthalmic delivery device includes a body defining a fluid reservoir and a pump in fluid communication with the reservoir. The delivery device also includes a nozzle that includes a dosage chamber for holding a dosage of fluid, a valve seat, and a valve cover. The valve cover extends about the valve seat and forms an interface therebetween and the valve seat includes an outlet aperture. The interface is in fluid communication with the outlet aperture and the dosage chamber, and at least part of the valve cover is movable between (i) a closed position with the valve cover engaging the valve seat to close the interface and form a fluid-tight seal therebetween, and (ii) an open position with at least part of the valve cover spaced away from the valve seat in response to fluid flowing through the outlet aperture at a pressure greater than a valve opening pressure to allow the passage of pressurized fluid therebetween. The valve seat and the valve cover are dimensioned to dispense the dosage of fluid through the interface at a velocity of equal to or less than 6 meters per second.
    • 眼科输送装置包括限定流体储存器的主体和与储存器流体连通的泵。 输送装置还包括喷嘴,该喷嘴包括用于保持一定量的流体的剂量室,阀座和阀盖。 阀盖围绕阀座延伸并且在它们之间形成界面,并且阀座包括出口孔。 所述界面与所述出口孔和所述剂量室流体连通,并且所述阀盖的至少一部分可在(i)与所述阀盖接合所述阀座的关闭位置之间移动以关闭所述界面并形成流体密封 密封在其间,和(ii)打开位置,其中阀盖的至少一部分响应于流体以大于阀打开压力的压力流过出口孔而与阀座间隔开,以允许加压流体在其间通过 。 阀座和阀盖的尺寸设计为以等于或小于6米/秒的速度通过界面分配流体的剂量。
    • 8. 发明申请
    • CONTAINER AND VALVE ASSEMBLY FOR STORING AND DISPENSING SUBSTANCES, AND RELATED METHOD
    • 用于储存和分配物质的集装箱和阀组件及相关方法
    • WO2006063360A3
    • 2007-04-19
    • PCT/US2005045110
    • 2005-12-12
    • MEDICAL INSTILL TECH INCPY DANIEL CCHAN JULIAN V
    • PY DANIELCHAN JULIAN V
    • B65D5/72
    • B65D35/46B65D47/205B65D47/2056B65D47/2081
    • A container and valve assembly for storing and dispensing substances including edible substances. The container is a tubular body that defines a storage chamber for storing the substance and a head portion for supports the valve assembly. The valve assembly includes a valve body and a valve seat surrounded by a flexible outer cover that includes a valve portion. A seem between the valve portion and valve seat form a one-way release valve wherein a portion of the seam remains closed when the substance is dispensed. To dispense the substance, pressure is applied to the body forcing the substance into the valve assembly, which in turn, controls the flow and release of the substance without exposing the remaining substance to the external atmosphere; thus, the sterility of the storage chamber and remaining substance is maintained, and the shelf life of the substance is increased.
    • 用于储存和分配包括可食用物质的物质的容器和阀组件。 容器是限定用于储存物质的储存室和用于支撑阀组件的头部的管状体。 阀组件包括阀体和由包括阀部分的柔性外盖包围的阀座。 在阀部分和阀座之间似乎形成单向释放阀,其中当物质被分配时,接缝的一部分保持关闭。 为了分配物质,将压力施加到身体上,迫使物质进入阀组件,这进而控制物质的流动和释放,而不将剩余物质暴露于外部大气中; 因此,保持储存室和剩余物质的无菌性,物质的保存期限增加。
    • 9. 发明申请
    • ONE-WAY VALVE AND APPARATUS AND METHOD OF USING THE VALVE
    • 单向阀和装置以及使用阀的方法
    • WO2007133297A3
    • 2008-02-28
    • PCT/US2007000419
    • 2007-01-05
    • MEDICAL INSTILL TECH INCPY DANIEL CCHAN JULIAN VADAMO BENOITHOULE NATHANIEL
    • PY DANIELCHAN JULIAN VADAMO BENOITHOULE NATHANIEL
    • B65D37/00B65D1/04
    • B67D1/0004B67D1/0082B67D1/10B67D1/108B67D2001/0827F16K15/145
    • A flexible pouch and valve assembly is provided for aseptically storing a substance, dispensing multiple portions of the stored substance therefrom, and maintaining substance remaining in the pouch in an aseptic condition sealed with respect to ambient atmosphere. The flexible pouch and valve assembly are receivable within a relatively rigid housing, and are adapted to cooperate with a pump for pumping discrete portions of substance from the pouch and through the one-way valve to dispense the substance therefrom. The assembly comprises a Flexible pouch defining therein a variable-volume storage chamber sealed with respect to the ambient atmosphere for aseptically storing therein multiple portions of the substance. A one way valve of the assembly includes a valve body defining an axially-extending valve seat and at least one flow aperture extending through the valve body and/or the valve seat. A valve cover is mounted on the valve body, and includes an axially-extending portion formed of an elastic material overlying the valve seat and covering a substantial axially-extending portion thereof. The valve portion defines a predetermined radial thickness and forms an interference fit with the valve seat. The valve portion and the valve seat define an axially-extending seam therebetween forming a normally closed, axially-extending valve opening, and the valve portion is movable radially between (i) a normally closed position with the valve portion engaging the valve seat, and (ii) an open position with at least a segment of the valve portion spaced radially away from the valve seat to connect the valve opening in fluid communication with the at least one flow aperture and thereby allow the passage of substance from the variable-volume storage chamber through the valve opening. In the normally closed and open positions, the one-way valve maintains substance remaining in the variable- volume storage chamber in an aseptic condition and sealed with respect to the ambient atmosphere.
    • 提供了一种柔性袋和阀组件,用于无菌存储物质,从其中分配多部分储存物质,并将残留在袋中的物质保持在相对于环境大气密封的无菌状态。 柔性袋和阀组件可接收在相对刚性的壳体内,并且适于与泵协作,用于泵送物质的离散部分并且通过单向阀从其分配物质。 组件包括柔性袋,其中限定有相对于环境大气密封的可变容积存储室,用于将物质的多个部分无菌存储。 组件的单向阀包括限定轴向延伸的阀座的阀体和延伸穿过阀体和/或阀座的至少一个流动孔。 阀盖安装在阀体上,并且包括由弹性材料形成的轴向延伸部分,该弹性材料覆盖在阀座上并覆盖其基本上轴向延伸的部分。 阀部分限定预定的径向厚度并与阀座形成过盈配合。 阀部分和阀座在其间限定了一个轴向延伸的接缝,形成一个常闭的,轴向延伸的阀门开口,阀部分在(i)与阀座接合的阀部分的常闭位置和 (ii)打开位置,其中所述阀部分的至少一个段与所述阀座径向间隔开,以将所述阀开口与所述至少一个流动孔流体连通,从而允许所述物质从所述可变容积存储器 室通过阀门开口。 在常开和常开位置,单向阀将物质保持在可变容积的储存室中,处于无菌状态,并相对于环境大气密封。