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1. 发明申请

WO2014204675A1 IMAGING SYSTEM AND METHOD FOR ENHANCED VISUALIZATION OF NEAR SURFACE VASCULAR STRUCTURES 审中-公开
标题翻译：成像系统和方法，用于增强近端表面血管结构的可视化
公开(公告)号：WO2014204675A1
公开(公告)日：2014-12-24
申请号：PCT/US2014/041271
申请日：2014-06-06
申请人： LAWRENCE LIVERMORE NATIONAL SECURITY, LLC
发明人： DEMOS, Stavros
IPC分类号： A61B6/00 , A61B5/02
CPC分类号： A61B5/489 , A61B5/0059 , A61B5/0075 , A61B5/0077 , A61B5/02007 , A61B5/7203 , A61B5/742 , A61B2562/0233
摘要： A sub-dermal structure visualization system and method is disclosed. The system may use an illumination module including: a near-infrared (NIR) light source adapted to substantially uniformly illuminate an imaged area including sub-dermal regions thereof with NIR light; and a first optical system including at least one optical element for controlling at least one of spectral and polarization properties of the NIR light prior to illuminating the imaged area. An imaging module rejects unwanted signals from an imaged area while passing desired optical signals that are to be received by an image acquisition module. The desired optical signals can comprise a vein visualization signal to assist in visualizing a vascular structure below a skin layer of a patient.
摘要翻译：公开了一种皮下结构可视化系统和方法。所述系统可以使用照明模块，所述照明模块包括：近红外（NIR）光源，适于用NIR光基本上均匀地照射包括其皮下区域的成像区域; 以及包括至少一个光学元件的第一光学系统，用于在照射成像区域之前控制NIR光的光谱和偏振特性中的至少一个。成像模块在通过要由图像采集模块接收的所需光信号的同时拒绝来自成像区域的不需要的信号。期望的光学信号可以包括静脉可视化信号，以帮助可视化患者皮肤层下面的血管结构。

2. 发明申请

WO2018175565A1 SYSTEM AND METHOD FOR CONTROLLING DEPTH OF IMAGING IN TISSUES USING FLUORESCENCE MICROSCOPY UNDER ULTRAVIOLET EXCITATION FOLLOWING STAINING WITH FLUORESCING AGENTS 审中-公开
公开(公告)号：WO2018175565A1
公开(公告)日：2018-09-27
申请号：PCT/US2018/023541
申请日：2018-03-21
申请人： LAWRENCE LIVERMORE NATIONAL SECURITY, LLC
发明人： LEVENSON, Richard , DEMOS, Stavros
IPC分类号： G01N21/64 , G01N33/52
CPC分类号： G01N21/6458 , G01N1/30 , G01N21/4795 , G01N33/52 , G01N35/00871 , G01N2021/6439
摘要： A method is disclosed for analyzing a thin tissue sample and adapted to be supported on a slide. The tissue sample may be placed on a slide and exposed to one or more different exogenous fluorophores excitable in a range of about 300 nm - 200 nm, and having a useful emission band from about 350 nm - 900 nm, and including one or more fluorescent dyes or fluorescently labeled molecular probes that accumulate in tissue or cellular components. The fluorophores may be excited with a first wavelength of UV light between about 200 nm - 290 nm. An optical system collects emissions from the fluorophores at a second wavelength, different from the first wavelength, which are generated in response to the first wavelength of UV light, to produce an image for analysis.

3. 发明申请

WO2015191631A1 PERSONAL ELECTRONIC DEVICE FOR PERFORMING MULTIMODAL IMAGING FOR NON-CONTACT IDENTIFICATION OF MULTIPLE BIOMETRIC TRAITS 审中-公开
标题翻译：个人电子设备，用于执行多重生物识别非联系识别的多模式成像
公开(公告)号：WO2015191631A1
公开(公告)日：2015-12-17
申请号：PCT/US2015/034965
申请日：2015-06-09
申请人： LAWRENCE LIVERMORE NATIONAL SECURITY, LLC
发明人： DEMOS, Stavros
IPC分类号： G06K9/00 , G06K19/07
CPC分类号： G06K9/00013 , G06K9/00885 , G06K9/00892 , G06K9/2018 , G06K2009/00932 , H04N5/2354 , H04N7/18
摘要： A hand holdable, portable apparatus for imaging a portion of an anatomy of a person, without physical contact with the anatomy. The apparatus has a housing, a touchscreen display mounted in the housing, and a plurality of illumination modules disposed on the housing and configured to provide illumination beams at different wavelengths and having different polarizations. A camera is supported on the housing and forms an imaging subsystem for capturing a plurality of acquired images produced by illumination from the illumination modules. A processing subsystem analyzes the acquired images and generates a new image which has enhanced contrast of features associated with at least one of a surface biometric trait of the portion of the anatomy, and/or a subsurface biometric trait of the portion of the anatomy. This image(s) can be used for verification of the person's identity by software incorporated in the portable apparatus or by transmitting information generated by the images to a remote data base.
摘要翻译：用于对人的解剖结构的一部分进行成像的手持式便携式装置，而不与身体接触解剖结构。该装置具有壳体，安装在壳体中的触摸屏显示器，以及多个照明模块，其设置在壳体上并被配置为提供不同波长的照明光束并且具有不同的偏振度。相机支撑在外壳上并且形成成像子系统，用于捕获从照明模块照明产生的多个获取的图像。处理子系统分析所获取的图像并生成具有与解剖结构部分的表面生物特征中的至少一个相关联的特征的增强的对比度和/或解剖结构部分的地下生物特征的新图像。该图像可以用于通过结合在便携式设备中的软件来验证人的身份，或者通过将图像生成的信息发送到远程数据库。

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