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1. 发明申请

WO2009072831A3 NOVEL USE OF FLJ25416 GENE 审中-公开
标题翻译： FLJ25416基因的新用途
公开(公告)号：WO2009072831A3
公开(公告)日：2009-08-20
申请号：PCT/KR2008007196
申请日：2008-12-05
申请人： KOREA RES INST OF BIOSCIENCE , SAMCHULLY PHARM CO LTD , WON MISUN , CHUNG KYUNG-SOOK , KIM YOUNG-JOO , CHOI SHIN-JUNG , YEOM YOUNG IL , KIM SEON-YOUNG , SONG KYUNG BIN , LEE HEE GU , SONG EUN YOUNG , KIM YOUNG HO , CHUN HO KYUNG , YUN CHAE-OK , KIM MOON HEE , JUNG KYEONG-EUN , CHO SUN-JUNG
发明人： WON MISUN , CHUNG KYUNG-SOOK , KIM YOUNG-JOO , CHOI SHIN-JUNG , YEOM YOUNG IL , KIM SEON-YOUNG , SONG KYUNG BIN , LEE HEE GU , SONG EUN YOUNG , KIM YOUNG HO , CHUN HO KYUNG , YUN CHAE-OK , KIM MOON HEE , JUNG KYEONG-EUN , CHO SUN-JUNG
IPC分类号： A61K38/17 , A61P35/00
CPC分类号： G01N33/57484 , A61K31/7088 , A61K38/1709 , C12N15/1135 , C12N15/86 , C12N2310/111 , C12N2310/14 , C12N2710/10343 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158 , G01N2500/00 , G01N2500/04
摘要： Provided are a composition for diagnosing cancer or screening an anticancer drug comprising an FLJ25416 gene or an antibody directed to a protein expressed from the FLJ25416 gene, a composition for treating cancer comprising an inhibitor of the gene or an inhibitor of the protein expressed from the gene and a pharmaceutically acceptable carrier, and a kit for diagnosing cancer comprising at least one of the FLJ25416 gene and the protein expressed from the FLJ25416 gene. The FLJ25416 gene is expressed at high level in specific cancer cells, and induces an increase in proliferation rate of normal cells. The expression of the gene is suppressed, which results in an inhibitory effect on cancer cell growth. Thus, the FLJ25416 gene can be used as a target gene for diagnosis or treatment of cancer.
摘要翻译：本发明提供了用于诊断癌症或筛选包含FLJ25416基因或针对由FLJ25416基因表达的蛋白质的抗体的抗癌药物的组合物，用于治疗癌症的组合物，所述组合物包含所述基因的抑制剂或由所述基因表达的蛋白质的抑制剂和药学上可接受的载体以及用于诊断癌症的试剂盒，其包含FLJ25416基因和由FLJ25416基因表达的蛋白质中的至少一种。 FLJ25416基因在特定癌细胞中高水平表达，并诱导正常细胞增殖速率增加。该基因的表达被抑制，这导致对癌细胞生长的抑制作用。因此，FLJ25416基因可以用作诊断或治疗癌症的靶基因。

2. 发明申请

WO2011149212A3 VEHICLE INTERMEDIATE SHAFT 审中-公开
标题翻译：车辆中间轴
公开(公告)号：WO2011149212A3
公开(公告)日：2012-03-01
申请号：PCT/KR2011003632
申请日：2011-05-17
申请人： KOREA DELPHI AUTOMOTIVE SYSTEM , KIM YOUNG-JOO , KIM HYON-CHUL , JUNG SE-HUN
发明人： KIM YOUNG-JOO , KIM HYON-CHUL , JUNG SE-HUN
IPC分类号： B62D1/16 , B62D1/19
CPC分类号： B62D1/16 , F16C3/035 , F16C29/046 , F16C2326/24
摘要： The present invention relates to a vehicle intermediate shaft, having a clearance reduction structure. The vehicle intermediate shaft includes: a tubular shaft which is opened at the front end thereof and formed with a hollow portion in the longitudinal direction; a solid shaft formed in the shape of a rod and inserted into the hollow portion; and a sliding member mounted between the inner surface of the tubular shaft and the outer surface of the solid shaft. The vehicle intermediate shaft further includes a preload section for pressing the outer surface of the tubular shaft. The preload section includes a pressing member for surrounding the outer surface of the tubular shaft, and a bushing for pressing and surrounding the outer surface of the pressing member. According to the present invention, it is possible to reduce clearances and lashes generated among the solid shaft, the slide member and the tubular shaft, and to prevent from creating noise. In addition, it is possible to improve the riding and handling performances of a vehicle and responsibility of a vehicle. Furthermore, production and quality control costs may be reduced by shortening process.
摘要翻译：本发明涉及具有间隙减小结构的车辆中间轴。车辆中间轴包括：管状轴，其在其前端开口并在纵向方向上形成有中空部分; 形成为杆状并插入中空部的实心轴; 以及安装在管状轴的内表面和实心轴的外表面之间的滑动构件。车辆中间轴还包括用于按压管状轴的外表面的预加载部。预压部包括用于围绕管状轴的外表面的按压部件和用于挤压和围绕按压部件的外表面的衬套。根据本发明，可以减少在实心轴，滑动构件和管状轴之间产生的间隙和睫毛，并且防止产生噪音。此外，可以提高车辆的骑行和处理性能以及车辆的责任。此外，通过缩短处理可以减少生产和质量控制成本。

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