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1. 发明申请

WO2012138100A2 ACTIVIN RECEPTOR TYPE II B INHIBITORS COMPRISING DLK1 EXTRACELLULAR WATER-SOLUBLE DOMAIN 审中-公开
标题翻译：包含DLK1细胞水溶性域的激活受体II型B抑制剂
公开(公告)号：WO2012138100A2
公开(公告)日：2012-10-11
申请号：PCT/KR2012002492
申请日：2012-04-03
申请人： KOREA RES INST OF BIOSCIENCE , ANTIBODY AND RECEPTOR THERAPEUTICS CO LTD , PARK YOUNG WOO , JO KI WON , LEE DONG HEE , LEE EUN KYUNG , JANG SE IL , PARK CHAN WOONG , KIM DONG JIN , KIM HYE NAN , PARK YUN JUNG , PARK JAE EUN , PARK JI HYUNG , YOO SEOK HO , JANG MYEONG HEE
发明人： PARK YOUNG WOO , JO KI WON , LEE DONG HEE , LEE EUN KYUNG , JANG SE IL , PARK CHAN WOONG , KIM DONG JIN , KIM HYE NAN , PARK YUN JUNG , PARK JAE EUN , PARK JI HYUNG , YOO SEOK HO , JANG MYEONG HEE
IPC分类号： A61K39/395 , A61P35/00 , C07K16/28 , C12N15/13
CPC分类号： C07K14/70575 , C07K14/485 , C07K2319/30
摘要： The present invention relates to an activin receptor type II B (ACVR2B) inhibitor which comprises the delta-like 1 homolog (DLK1) extracellular water-soluble domain. More specifically, the present invention relates to an extracellular soluble domain of DLK1; fragments of the extracellular soluble domain of DLK1; mutants of the extracellular soluble domain of DLK1; a composition for suppressing ligand linkage with the ACVR2B receptor, which includes a fragment of the mutants as an active ingredient; and a pharmaceutical composition for prevention and treatment of diseases which comprises the same. The composition of the present invention competitively binds to the ACVR2B receptor and inhibits the binding of an ACVR2B ligand to the ACVR2B receptor, which inhibits protein signalling associated with such ligands, and will be useful for prevention and treatment of diseases associated therewith.
摘要翻译：本发明涉及包含δ-样1同系物（DLK1）细胞外水溶性结构域的激活素受体IIB型（ACVR2B）抑制剂。更具体地，本发明涉及DLK1的细胞外可溶性结构域; DLK1细胞外可溶性结构域的片段; DLK1细胞外可溶性结构域的突变体; 用于抑制与ACVR2B受体的配体键合的组合物，其包含突变体的片段作为活性成分; 以及用于预防和治疗包含该疾病的疾病的药物组合物。本发明的组合物竞争性地结合ACVR2B受体并且抑制ACVR2B配体与ACVR2B受体的结合，其抑制与这种配体相关的蛋白质信号，并且将可用于预防和治疗与之相关的疾病。

2. 发明申请

WO2012138102A2 DLK1-SPECIFIC HUMAN ANTIBODIES AND PHARMACEUTICAL COMPOSITION CONTAINING SAME 审中-公开
标题翻译： DLK1特异性人体抗体和含有其的药物组合物
公开(公告)号：WO2012138102A2
公开(公告)日：2012-10-11
申请号：PCT/KR2012002496
申请日：2012-04-03
申请人： KOREA RES INST OF BIOSCIENCE , PARK YOUNG WOO , JO KI WON , LEE DONG HEE , YUN SEON HA , SOHN MYUNG HO , KIM KYUNG JIN , KIM DONG JIN , LEE YOO RA , PARK CHAN WOONG
发明人： PARK YOUNG WOO , JO KI WON , LEE DONG HEE , YUN SEON HA , SOHN MYUNG HO , KIM KYUNG JIN , KIM DONG JIN , LEE YOO RA , PARK CHAN WOONG
IPC分类号： C07K16/28 , A61K39/395 , A61P35/00 , C12N15/13
CPC分类号： C07K14/485 , C07K16/28 , C07K2317/21
摘要： The present invention relates to human antibodies that binds specifically to the extracellular water-soluble domain of DLK1 and fragments which include antigen-binding sites thereof; a polynucleotide which encodes for the human antibodies or fragments thereof; a recombinant vector containing the polynucleotide; transformants transformed with the recombinant vector; method for manufacturing the human antibodies or fragments thereof; a pharmaceutical composition for preventing or treating disease which includes the human antibodies or fragment thereof; and diagnostic kits. Human antibodies and fragments which include antigen-binding sites that bind specifically to the extracellular water-soluble domain of DLK1 of the present invention show anti-tumor activity. By significantly raising the binding capacity of the DLK1 extracellular water-soluble domain to the Activin receptor type II B (ACVR2B), utility is demonstrated for prevention and treatment of diseases associated with ACVR2B signal transduction including related metabolic disorders, immune disease, liver diseases, and cancer.
摘要翻译：本发明涉及与DLK1的细胞外水溶性结构域特异性结合的人抗体和包括其抗原结合位点的片段; 编码人抗体或其片段的多核苷酸; 含有多核苷酸的重组载体; 用重组载体转化的转化体; 制造人抗体或其片段的方法; 用于预防或治疗疾病的药物组合物，其包括人抗体或其片段; 和诊断试剂盒。包括与本发明的DLK1的细胞外水溶性结构域特异性结合的抗原结合位点的人抗体和片段显示抗肿瘤活性。通过显着提高DLK1细胞外水溶性结构域与激活素受体IIB（ACVR2B）的结合能力，证明了预防和治疗与ACVR2B信号转导相关的疾病的效用，包括相关代谢紊乱，免疫疾病，肝脏疾病，和癌症。

3. 发明申请

WO2012148122A2 ATPG8 PROTEIN HAVING FUNCTIONS OF INCREASED PRODUCTIVITY, DELAYED AGING, AND RESISTANCE TO STRESS OF PLANT, GENE THEREOF, AND USE THEREOF 审中-公开
标题翻译：具有增加生产力，延迟衰老和抗性的植物，基因及其应用的功能的ATPG8蛋白质及其用途
公开(公告)号：WO2012148122A2
公开(公告)日：2012-11-01
申请号：PCT/KR2012002967
申请日：2012-04-18
申请人： GENOMINE INC , LEE DONG HEE , KIM KOOK JIN , LEE IN CHUL
发明人： LEE DONG HEE , KIM KOOK JIN , LEE IN CHUL
IPC分类号： A01H5/00 , C12N15/29 , C12N15/82
CPC分类号： C07K14/415 , C12N15/8261 , C12N15/8271 , Y02A40/146
摘要： Disclosed in the present invention are an ATPG8 protein having functions of delayed aging, increased productivity, and resistance to stress of a plant, a gene thereof, and a use thereof. The transformed and overexpressed plant body not only shows a feature of increased productivity, but also features of delayed aging and resistance to stress.
摘要翻译：在本发明中公开了具有延迟衰老，生产力提高和抗胁迫作用的ATPG8蛋白及其基因及其用途。转化和过表达的植物体不仅显示生产力提高的特征，而且还具有延迟衰老和抗压力的特征。

4. 发明申请

WO2010005180A3 METHOD AND SYSTEM FOR MANAGING HANDOVER IN RADIO ACCESS NETWORKS 审中-公开
标题翻译：在无线接入网络中管理切换的方法和系统
公开(公告)号：WO2010005180A3
公开(公告)日：2010-03-25
申请号：PCT/KR2009003202
申请日：2009-06-16
申请人： SAMSUNG ELECTRONICS CO LTD , LEE DONG HEE , YEOUM TAE SUN , VAISHALI PAISAL
发明人： LEE DONG HEE , YEOUM TAE SUN , VAISHALI PAISAL
IPC分类号： H04W36/14 , H04W84/04
CPC分类号： H04W36/30 , H04W36/0022 , H04W36/005 , H04W36/0066 , H04W36/0083 , H04W36/14 , H04W80/04
摘要： A method and system for managing handover from a first radio access network to second radio access network is provided. The method includes receiving information associated with one or more neighboring cells from a User Equipment (UE). The information associated with the one or more neighboring cell is measurement reports. Thereafter, the method deciding to perform Handover (HO) based on the measurement reports for the UE from the first radio access network to the second radio access network. Further, the method identifies a target cell from the one or more neighboring cells. The method then determines target cell capabilities. Thereby, the method sends at least one of a handover required message and a relocation required message along with the target cell capabilities to a core network element. The core network element then manages voice bearers and non-voice bearers based on the target cell capabilities.
摘要翻译：提供了一种用于管理从第一无线接入网向第二无线接入网的切换的方法和系统。该方法包括从用户设备（UE）接收与一个或多个相邻小区相关联的信息。与一个或多个相邻小区相关联的信息是测量报告。之后，该方法基于针对UE的测量报告从第一无线接入网决定执行切换（HO）到第二无线接入网。此外，该方法从一个或多个相邻小区识别目标小区。该方法然后确定目标小区能力。从而，该方法将需要切换的消息和需要重定位的消息中的至少一个连同目标小区能力一起发送到核心网络单元。核心网络单元然后基于目标小区能力来管理语音承载和非语音承载。

5. 发明申请

WO2011122761A3 GSDL2 PROTEIN HAVING A LIFE-EXTENSION FUNCTION FOR PLANTS AND A STRESS RESISTANCE FUNCTION FOR PLANTS, GENE THEREOF, AND USE THEREOF 审中-公开
标题翻译： GSDL2蛋白具有用于植物的生物延伸功能和植物的抗应力功能，其基因及其使用
公开(公告)号：WO2011122761A3
公开(公告)日：2011-11-24
申请号：PCT/KR2011000593
申请日：2011-01-28
申请人： GENOMINE INC , LEE DONG HEE , KIM KOOK JIN , LEE IN CHUL
发明人： LEE DONG HEE , KIM KOOK JIN , LEE IN CHUL
IPC分类号： A01H5/00 , C07K14/415 , C12N15/29 , C12N15/82
CPC分类号： C07K14/415 , C12N15/8266 , C12N15/8271 , C12N15/8273
摘要： The present discloses a GSDL2 protein with a life-extension function and a stress resistance function for plants, a gene thereof, and a use thereof. Plants transformed with the gene exhibit a property of extended lifespan, a property of production increase such as individual size, and resistance to environmental stress - particularly to oxidative stress and salt stress.
摘要翻译：本发明公开了具有延长寿命和对植物的胁迫抵抗功能的GSDL2蛋白质及其基因及其用途。用该基因转化的植物表现出寿命延长，生产增加的特性，如个体大小，耐环境胁迫 - 特别是对氧化应激和盐胁迫。

6. 发明申请

WO2010095910A3 POLYPEPTIDE HAVING FUNCTION FOR DELAYING ANTHESIS OR SUPPRESSING GROWTH, POLYNUCLEOTIDE ENCODING THE SAME, AND USE THEREOF 审中-公开
标题翻译：具有延迟衰老或抑制生长的功能的多肽，编码其的多核苷酸及其用途
公开(公告)号：WO2010095910A3
公开(公告)日：2011-01-13
申请号：PCT/KR2010001112
申请日：2010-02-23
申请人： POSTECH ACAD IND FOUND , NAM HONG GIL , PARK KYUNG MOK , LEE DONG HEE , KIM JEONG SIK , LIM PYUNG OK
发明人： NAM HONG GIL , PARK KYUNG MOK , LEE DONG HEE , KIM JEONG SIK , LIM PYUNG OK
IPC分类号： C07K14/415 , A01H1/00 , C12N15/29 , C12N15/63
CPC分类号： C07K14/415 , C12N15/827
摘要： The present invention discloses a polypeptide having a function for delaying anthesis or suppressing growth, a polynucleotide encoding the same, and a use thereof. Specifically, the present invention discloses a polypeptide having a function of delaying anthesis or suppressing growth, a polynucleotide encoding the same, a method for manufacturing plants with a phenotype of anthesis delay, a method for manufacturing plants with a phenotype of growth suppression, a selecting transgenic plants, and a method for screening materials which delay anthesis or suppress growth of plants.
摘要翻译：本发明公开了具有延迟开花或抑制生长的功能的多肽，编码该多肽的多核苷酸及其用途。具体地，本发明公开了具有延迟开花或抑制生长的功能的多肽，编码该多肽的多核苷酸，具有开花延迟表型的植物的制造方法，具有生长抑制表型的植物的制造方法转基因植物，以及用于筛选延迟开花或抑制植物生长的材料的方法。

7. 发明申请

WO2010041852A3 METHOD AND SYSTEM FOR PERPETUAL COMPUTING USING NON-VOLATILE RANDOM ACCESS MEMORY (NVRAM) 审中-公开
标题翻译：使用非易失性随机存取存储器（NVRAM）进行PERPETUAL计算的方法和系统
公开(公告)号：WO2010041852A3
公开(公告)日：2010-07-29
申请号：PCT/KR2009005684
申请日：2009-10-06
申请人： NOH SAM HYUK , KIM HYOJIN , KIM EUNSAM , CHOI JONG MOO , LEE DONG HEE , MOON YOUNG-JE , DOH IN HWAN , PARK JUNG-SOO
发明人： NOH SAM HYUK , KIM HYOJIN , KIM EUNSAM , CHOI JONG MOO , LEE DONG HEE , MOON YOUNG-JE , DOH IN HWAN , PARK JUNG-SOO
IPC分类号： G06F1/30 , G06F9/06 , G06F12/16
CPC分类号： G06F1/30 , G06F9/3863 , G06F11/1441
摘要： Disclosed are a computing system utilizing a non-volatile random access memory (NVRAM), and an operating method thereof. The present invention provides a perpetual computing environment in which a program is executed on the non-volatile random access memory (NVRAM) in a system in which the entirety or a part of the memory consists of a non-volatile random access memory (NVRAM), and the data and the state of the program being run on the non-volatile random access memory (NVRAM) can be perfectly restored when the system is ended and rebooted.
摘要翻译：公开了利用非易失性随机存取存储器（NVRAM）的计算系统及其操作方法。本发明提供了一种永久性计算环境，其中在其中整个或一部分存储器由非易失性随机存取存储器（NVRAM）组成的系统中的非易失性随机存取存储器（NVRAM）上执行程序，，并且当系统结束并重新启动时，可以完美地恢复在非易失性随机存取存储器（NVRAM）上运行的程序的数据和状态。

8. 发明申请

WO2010120046A3 APPARATUS FOR PRODUCING HIGHER-PURITY CARBON DIOXIDE FOR RECOVERING CARBON DIOXIDE FROM WASTE GAS CONTAINING FLAMMABLE IMPURITIES, AND METHOD FOR RECOVERING HIGHER-PURITY CARBON DIOXIDE USING SAME 审中-公开
标题翻译：用于生产用于从含有可燃性污染物的废气中回收二氧化碳的高倍率二氧化碳的装置以及使用其回收高纯度二氧化碳的方法
公开(公告)号：WO2010120046A3
公开(公告)日：2011-01-06
申请号：PCT/KR2010001563
申请日：2010-03-12
申请人： HONAM PETROCHEMICAL CORP , HANDOK ENG CO LTD , PARK GI CHUL , KIM YEON SEOP , LEE DONG HEE , HWANG YEAL SOON , LEE EUN IL
发明人： PARK GI CHUL , KIM YEON SEOP , LEE DONG HEE , HWANG YEAL SOON , LEE EUN IL
IPC分类号： C01B32/50 , B01D53/92
CPC分类号： B01D53/62 , B01D2256/22 , B01D2257/708 , C01B32/50 , F23G5/50 , F23G7/065 , F23G2207/103 , F23G2207/104 , F23G2207/30 , F23G2208/10 , F23G2900/55003 , F23G2900/55011 , F23J2215/50 , F23L7/007 , Y02C10/04 , Y02E20/322 , Y02E20/344 , Y02P20/152
摘要： The present invention relates to a method and an apparatus for recovering carbon dioxide using pure oxygen, and to a method and an apparatus which produce higher-purity carbon dioxide through a combustion system using pure oxygen, for recovering carbon dioxide from waste gas containing flammable impurities. The apparatus of the present invention comprises: a combustion device for burning VOC in the waste gas containing flammable impurities; an outdoor air suction blower and a burner for increasing the indoor temperature of the combustion device; a pressure reduction valve for reducing the pressure of the waste gas; a mixer for mixing pure oxygen into the waste gas; an oximeter and an oxygen-supplying device; a low explosive limit (LEL) measuring instrument for measuring the VOC concentration in the waste gas; an auxiliary fuel supply device; a recycling air blower; and a heat exchanger for removing moisture from the burnt gas and heating the introduced waste gas.
摘要翻译：本发明涉及使用纯氧回收二氧化碳的方法和装置，以及通过使用纯氧的燃烧系统产生更高纯度二氧化碳的方法和装置，用于从含有可燃性杂质的废气中回收二氧化碳。本发明的装置包括：用于在含有易燃杂质的废气中燃烧VOC的燃烧装置; 室外空气抽风机和用于提高燃烧装置的室内温度的燃烧器; 用于降低废气压力的减压阀; 用于将纯氧混合到废气中的混合器; 血氧计和供氧装置; 用于测量废气中VOC浓度的低爆炸极限（LEL）测量仪器; 辅助燃料供应装置; 回收鼓风机; 以及用于从燃烧气体中除去水分并加热引入的废气的热交换器。

9. 发明申请

WO2010030115A2 TRAJECTORY ADJUSTMENT APPARATUS 审中-公开
标题翻译：轨道调整装置
公开(公告)号：WO2010030115A2
公开(公告)日：2010-03-18
申请号：PCT/KR2009005105
申请日：2009-09-09
申请人： JUNG IN , LEE DONG HEE
发明人： JUNG IN , LEE DONG HEE
IPC分类号： F41G3/26
CPC分类号： F41G1/54 , F41G1/30 , F41G1/345 , F41G1/473 , F41G11/003
摘要： The present invention relates to a trajectory adjustment apparatus. The trajectory adjustment apparatus according to the present invention comprises a mount which is placed on a gun body, a movable member which is placed on top of the mount and wherein a projection is formed in one side thereof, a joint shaft which is inserted in the movable member and permitted to rotate, a rotary shaft which perpendicularly penetrates the rotary shaft and is installed in the mount, an adjustment member which vertically adjusts the turning angle of the movable member, and a trajectory adjustment member. In the trajectory adjustment member, a guide groove where the projection is inserted is diagonally formed on a flat surface thereof and fastened in one side of the mount. The trajectory adjustment member includes a guide plate which horizontally turns the movable member according to the vertical turning of the movable member.
摘要翻译：轨迹调整装置技术领域本发明涉及一种轨迹调整装置。根据本发明的轨道调节装置包括放置在枪体上的支架，放置在支架顶部上的可移动构件，其中在其一侧形成有突起;接合轴，其插入允许旋转的旋转轴，垂直穿过旋转轴并安装在底座中的旋转轴，垂直调节可动构件的旋转角度的调节构件以及轨道调节构件。在轨道调节构件中，突起插入其中的导向槽对角地形成在其平坦表面上并且紧固在支架的一侧中。轨迹调整构件包括导向板，该导向板根据可动构件的垂直转动水平地转动可动构件。

10. 发明申请

WO2009020343A3 DIAGNOSTIC COMPOSITION AND KIT FOR RENAL CELL CARCINOMA 审中-公开
标题翻译：诊断组合物和用于肾细胞癌的药盒
公开(公告)号：WO2009020343A3
公开(公告)日：2009-04-23
申请号：PCT/KR2008004562
申请日：2008-08-06
申请人： DCD INC , KIM DONG SU , CHO NAM HOON , NA HYUNG JIN , CHOI YOUNG DEUK , JANG JAE HO , KIM HYE KYING , PARK MO YOEL , PARK WON MAN , KIM TAE-HOON , LEE DONG HEE , PARK KYUNG MOK
发明人： KIM DONG SU , CHO NAM HOON , NA HYUNG JIN , CHOI YOUNG DEUK , JANG JAE HO , KIM HYE KYING , PARK MO YOEL , PARK WON MAN , KIM TAE-HOON , LEE DONG HEE , PARK KYUNG MOK
IPC分类号： G01N33/574
CPC分类号： G01N33/57438 , C07K16/3038 , C07K16/40 , G01N33/5011 , G01N33/5017 , G01N33/573 , G01N2333/91017
摘要： Disclosed herein are a composition and a kit for diagnosing renal cell carcinoma. The composition and kit employ, as a renal cell carcinoma marker, nicotinamide N- methyltransferase, L-plastin, secretagogin, NM23A, CapG, which is an actin regulatory protein, and/or C4a anaphylatoxin.
摘要翻译：本文公开了用于诊断肾细胞癌的组合物和试剂盒。作为肾细胞癌标记物的组合物和试剂盒使用烟酰胺N-甲基转移酶，L-丝庭蛋白，促分泌素，NM23A，CapG，其是肌动蛋白调节蛋白，和/或C4a过敏毒素。

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