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1. 发明申请

WO2014111782A1 ARTERIAL SPIN LABELING WITH REDUCED ACOUSTIC NOISE EMISSIONS AND METHOD OF OPERATION THEREOF 审中-公开
标题翻译：具有减少的声音噪声排放的椎体旋转标签及其操作方法
公开(公告)号：WO2014111782A1
公开(公告)日：2014-07-24
申请号：PCT/IB2013/061432
申请日：2013-12-31
申请人： KONINKLIJKE PHILIPS N.V. , PHILIPS DEUTSCHLAND GMBH
发明人： HELLE, Michael Günter , NIELSEN, Tim
IPC分类号： G01R33/563
CPC分类号： G01R33/56366 , G01R33/3854 , G01R33/543
摘要： A magnetic resonance imaging (MRI) system (100, 600) that generates information indicative of a fluid flow in accordance with a pseudo-continuous arterial spin labeling (pCASL) method. The MRI system may include at least one controller (104, 610) configured to generate a pseudo-continuous arterial spin labeling (pCASL) pulse sequence (200) including at least a first gradient (GR) pulse sequence (207) having a sinusoidal waveform including a plurality of cycles, and a second radio frequency (RF) pulse sequence (205) including a half-wave rectified sinusoidal waveform having a plurality of cycles and which is synchronous with the first GR pulse sequence; label at least part of the fluid flow in a labeling region during a labeling mode using the pCASL pulse sequence; acquire label and control image information of the fluid flow at an imaging region proximal to downstream of the labeling region; and/or generate image information in accordance with a difference of the acquired label and control image information. The sinusoidal gradient waveform results in less acoustic noise during execution of the pulse sequence.
摘要翻译：根据伪连续动脉自旋标记（pCASL）方法产生指示流体流动的信息的磁共振成像（MRI）系统（100,600）。 MRI系统可以包括被配置为产生伪连续动脉自旋标记（pCASL）脉冲序列（200）的至少一个控制器（104,610），该脉冲序列（200）至少包括具有正弦波形的第一梯度（GR）脉冲序列（207）包括多个周期，以及第二射频（RF）脉冲序列（205），其包括具有多个周期并与第一GR脉冲序列同步的半波整流正弦波形; 在使用pCASL脉冲序列的标记模式期间在标记区域中标记至少一部分流体流动; 获取标签和控制在标签区域下游的成像区域处的流体流动的图像信息; 和/或根据获取的标签和控制图像信息的差异生成图像信息。正弦梯度波形在执行脉冲序列期间导致较少的声学噪声。

2. 发明申请

WO2019201968A1 AUTOMATIC ARTIFACT DETECTION AND PULSE SEQUENCE MODIFICATION IN MAGNETIC RESONANCE IMAGING 审中-公开
公开(公告)号：WO2019201968A1
公开(公告)日：2019-10-24
申请号：PCT/EP2019/059872
申请日：2019-04-17
申请人： KONINKLIJKE PHILIPS N.V.
发明人： SOMMER, Karsten , SAALBACH, Axel , HELLE, Michael Günter , WEISS, Steffen , SCHÜLKE, Christophe Michael Jean
IPC分类号： G01R33/56 , A61B5/055 , G01R33/565 , G06T7/00
摘要： The invention provides for a magnetic resonance imaging system (100, 300). The execution of machine executable instructions causes a processor (130) controlling the magnetic resonance imaging system to control (200) the magnetic resonance imaging system to acquire the magnetic resonance imaging data (144) using pulse sequence commands (142) and reconstruct (202) a magnetic resonance image (148). Execution of the machine executable instructions causes the processor to receive (204) a list of suggested pulse sequence command changes (152) by inputting the magnetic resonance image and image metadata (150) into an MRI artifact detection module (146, 146', 146"). The MRI artifact detection module comprises at least one neural network, which has been trained using images from failed magnetic resonance imaging protocols and/or magnetic resonance data extracted from the magnetic resonance imaging protocols labeled as failed accessed from a log file (312) which logs the execution of previous magnetic resonance imaging protocols. Execution of the machine executable instructions further causes the processor to receive (206) a selection of a chosen pulse sequence command change (158) from the list of suggested pulse sequence command changes. Execution of the machine executable instructions further causes the processor to modify (208) the pulse sequence commands using the chosen pulse sequence command change.

3. 发明申请

WO2019238466A1 ELECTRICAL PROPERTIES TOMOGRAPHY MAPPING OF CONDUCTIVITY CHANGES 审中-公开
公开(公告)号：WO2019238466A1
公开(公告)日：2019-12-19
申请号：PCT/EP2019/064432
申请日：2019-06-04
申请人： KONINKLIJKE PHILIPS N.V.
发明人： HELLE, Michael Günter , KATSCHER, Ulrich
IPC分类号： A61B5/00 , A61B5/04
摘要： The invention provides for a medical imaging system (100, 300) comprising: a memory (110) for storing machine executable instructions (120); and a processor (104) for controlling the medical imaging system. Execution of the machine executable instructions causes the processor to: receive (200) a resting group of B1 phase maps (122) of a region (309) of interest of a subject (318); receive (202) an active group of B1 phase maps (124) of the region of interest of the subject; calculate (204) a resting group of conductivity maps (126) for the region of interest using the resting group of B1 phase maps according to an electrical properties tomography algorithm; calculate (206) an active group of conductivity maps (128) for the region of interest using the active group of B1 phase maps according to the electrical properties tomography algorithm; and calculate (208) a conductivity change mapping (130) for the region of interest using the resting group of conductivity maps and the active group of conductivity maps.

4. 发明申请

WO2015158879A1 MRI INVOLVING THE ACQUISITION OF AN ANGIOGRAPHY WEIGHTED IMAGE AND OF A PERFUSION WEIGHTED IMAGE 审中-公开
标题翻译：涉及摄影加权图像和灌注加权图像的MRI
公开(公告)号：WO2015158879A1
公开(公告)日：2015-10-22
申请号：PCT/EP2015/058359
申请日：2015-04-17
申请人： KONINKLIJKE PHILIPS N.V. , ACADEMISCH ZIEKENHUIS LEIDEN
发明人： HELLE, Michael Günter , VAN OSCH, Matthias Johannes Paulus
IPC分类号： G01R33/483 , G01R33/563
CPC分类号： G01R33/56366 , A61B5/0044 , A61B5/026 , A61B5/055 , G01R33/4838 , G01R33/543 , G01R33/5635
摘要： The present invention provides a method for magnetic resonance (MR) imaging of a subject of interest (120) using arterial spin labeling, comprising the steps of performing a labeling module (200) by applying magnetic and/or radio frequency (RF) fields to the subject of interest (120) for labeling arterial blood in at least a labeling region (144) thereof, performing a first readout module (202) to obtain first MR information of the subject of interest (120) in a region of interest (142) using first parameters, performing a second readout module (204) to obtain second MR information of the subject of interest (120) in a region of interest (142) using second parameters, and performing MR image generation of a region of interest (142) based on the first and second MR information, wherein the first and second parameters of the first and second readout module (202, 204) are chosen to be different parameters. The invention also provides a MR imaging system (110) adapted to perform the above method and a software package for upgrading a MR imaging system (110), whereby the software package contains instructions for controlling the MR imaging system (110) according to the above method.
摘要翻译：本发明提供使用动脉自旋标记对感兴趣对象（120）进行磁共振（MR）成像的方法，包括以下步骤：通过将磁场和/或射频（RF）场施加到用于在至少其标签区域（144）中标记动脉血的感兴趣的主题（120），执行第一读出模块（202）以获得感兴趣区域（142）中的感兴趣对象（120）的第一MR信息（142））使用第一参数，执行第二读出模块（204），以使用第二参数获得感兴趣区域（142）中感兴趣对象（120）的第二MR信息，并且执行感兴趣区域（142）的MR图像生成），其中第一和第二读出模块（202,204）的第一和第二参数被选择为不同的参数。本发明还提供一种适于执行上述方法的MR成像系统（110）和用于升级MR成像系统（110）的软件包，由此软件包含有用于控制根据上述的MR成像系统（110）的指令方法。

5. 发明申请

WO2020245091A1 SENSOR SYSTEM FOR INCREASING SECURITY IN MR ENVIRONMENTS 审中-公开
公开(公告)号：WO2020245091A1
公开(公告)日：2020-12-10
申请号：PCT/EP2020/065156
申请日：2020-06-02
申请人： KONINKLIJKE PHILIPS N.V.
发明人： DJAJADININGRAT, Johan Partomo , HELLE, Michael Günter , VOGTMEIER, Gereon , WEISS, Steffen , KNOESTER, Jaap
IPC分类号： G01R33/28 , G01R33/038
摘要： The invention is directed to a sensor system (100) for increasing security of a use of at least one magnetic object (102) in vicinity of an MR imaging device (200), wherein at least one magnetic property of the magnetic object (102) can be measure and evaluated in order to increase the safe use of the magnetic object (102) within MR environments.

6. 发明申请

WO2017182303A1 MAGNETIC RESONANCE IMAGING OF ARTERIAL STRUCTURES 审中-公开
标题翻译：动脉结构的磁共振成像
公开(公告)号：WO2017182303A1
公开(公告)日：2017-10-26
申请号：PCT/EP2017/058482
申请日：2017-04-10
申请人： KONINKLIJKE PHILIPS N.V.
发明人： HELLE, Michael Günter , LINDNER, Thomas
IPC分类号： G01R33/563
CPC分类号： G01R33/56316 , G01R33/5635 , G01R33/56366
摘要： The invention provides for a medical imaging system (100, 1200). The medical imaging system comprises: a memory (136) for storing machine executable instructions (170), and a processor (130) for controlling the medical imaging system. Execution of the machine executable instructions causes the processor to: receive (304, 1000) a tagged ASL magnitude image (148) of a region of interest of a subject (118); receive (306, 1002) a control ASL magnitude image (150) of the region of interest of the subject; construct (308, 1004) an arterial image (152) by subtracting the control ASL magnitude image and the tagged ASL magnitude image; construct (310, 1006) an arterial mask (154) using the arterial image by identifying arteries in the arterial image; receive (312, 1008) a phase contrast magnetic resonance image (156, 158, 160) of at least a portion of the region of interest of the subject; and construct a venous image (164) at least partially by setting voxels of the phase contrast image within the at least a portion of the region of interest that are within the arterial mask to the predetermined background value.
摘要翻译：本发明提供了一种医学成像系统（100,1200）。医学成像系统包括：用于存储机器可执行指令（170）的存储器（136）以及用于控制医学成像系统的处理器（130）。机器可执行指令的执行使得处理器：接收（304,1000）对象（118）的感兴趣区域的标记的ASL幅度图像（148）; 接收（306,1002）所述对象的所述感兴趣区域的控制ASL幅度图像（150）; 通过减去所述控制ASL幅度图像和所述标记的ASL幅度图像来构建（308,1004）动脉图像（152）; 通过识别动脉图像中的动脉，使用动脉图像构建（310,1006）动脉面罩（154）接收（312,1008）所述对象的所述感兴趣区域的至少一部分的相位对比磁共振图像（156,158,160）并且至少部分地通过将位于动脉掩模内的感兴趣区域的至少一部分内的相位对比度图像的体素设置为预定背景值来构建静脉图像（164）。

7. 发明申请

WO2015150065A1 A METHOD ESTIMATING A PSEUDO HOUNSFIELD UNIT VALUE 审中-公开
标题翻译：一种估计PSEUDO HOUNSFIELD单位值的方法
公开(公告)号：WO2015150065A1
公开(公告)日：2015-10-08
申请号：PCT/EP2015/055539
申请日：2015-03-17
申请人： KONINKLIJKE PHILIPS N.V.
发明人： SCHADEWALDT, Nicole , HELLE, Michael Günter , SCHULZ, Heinrich , RENISCH, Steffen
IPC分类号： G06T5/00 , G06T5/50 , G01R33/48
CPC分类号： G01R33/5608 , A61B5/0042 , A61B5/055 , G01R33/481 , G01R33/4828 , G06T5/008 , G06T5/50 , G06T7/0012 , G06T7/11 , G06T2207/10088 , G06T2207/30008 , G06T2207/30024
摘要： The application discloses a method for estimating a pseudo CT Hounsfield Unit value for a volume element within a subject from a plurality of magnetic resonance images having different contrasts. The method comprising the steps of: determination of a relative prevalence of a first tissue class and second tissue class within the volume element from a first magnetic resonance image and second magnetic resonance image respectively. Then a a relative prevalence of a third tissue class is determined within the volume element based on substraction of a relative prevalence of the first and/or second tissue class from a total tissue prevalence. A reference Hounsfield Unit value is provided for the first, second and third tissue class. Finally, a pseudo Housfield value is estimated for the volume element by determining a weighted sum of the first, second and third reference Hounsfield unit value, with weight factors which are based on the determined relative prevalences of the first, second and third tissue class.
摘要翻译：本申请公开了一种用于从具有不同对比度的多个磁共振图像估计被摄体内的体积元素的伪CT Hounsfield单位值的方法。该方法包括以下步骤：分别从第一磁共振图像和第二磁共振图像确定体积元素内的第一组织类别和第二组织类别的相对流行率。然后，基于来自总组织流行率的第一和/或第二组织类别的相对流行率的减小，在体积元素内确定第三组织类别的相对流行率。为第一，第二和第三组织分类提供参考Hounsfield单位值。最后，通过基于所确定的第一，第二和第三组织类的相对流行性的权重因子确定第一，第二和第三参考Hounsfield单位值的加权和来估计体积元素的伪Housfield值。

8. 发明申请

WO2014147508A2 A METHOD FOR K-SPACE SAMPLING 审中-公开
标题翻译： K空间采样的方法
公开(公告)号：WO2014147508A2
公开(公告)日：2014-09-25
申请号：PCT/IB2014/059513
申请日：2014-03-07
申请人： KONINKLIJKE PHILIPS N.V. , PHILIPS DEUTSCHLAND GMBH
发明人： DONEVA, Mariya Ivanova , HELLE, Michael Günter , BOERNERT, Peter
IPC分类号： G01R33/561
CPC分类号： G01R33/5611 , G01R33/4818
摘要： The present invention relates to a magnetic resonance imaging MRI system (100) for acquiring magnetic resonance data from a target volume in a subject (118), the magnetic resonance imaging system (100) comprises: a memory (136) for storing machine executable instructions; and a processor (130) for controlling the MRI system (100), wherein execution of the machine executable instructions causes the processor (130) to: determine an energy distribution (301-305) over a k-space domain of the target volume; receive a reduction factor representing a degree of under-sampling of the k-space domain; derive from the energy distribution (301-305) and the received reduction factor a sampling density function; derive from the sampling density function an energy dependent sampling pattern of the k-space domain; control the MRI system (100) to acquire under-sampled k-space data using a pulse sequence that samples the k-space domain along the derived sampling pattern; apply a compressed sensing reconstruction to the acquired under-sampled data to reconstruct an image of the target volume.
摘要翻译：磁共振成像系统（100）包括：存储器（136），用于存储机器可执行指令 ; 以及用于控制所述MRI系统（100）的处理器（130），其中所述机器可执行指令的执行使所述处理器（130）确定所述目标体积的k空间域上的能量分布（301-305）接收表示k空间域的低采样度的缩小因子; 从能量分布（301-305）和收到的减少因子得出采样密度函数; 从采样密度函数导出k空间域的能量相关采样模式; 控制MRI系统（100）使用沿着导出的采样模式对k-空间域进行采样的脉冲序列来获取欠采样的k空间数据; 对所获取的未采样数据应用压缩感测重建以重建目标体积的图像。

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